Clinical trials
Heart Failure NYHA Class III clinical trials
Below are recruiting heart failure nyha class iii clinical trials, each written for real people, not researchers. We’re tracking 134 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05873634Recruiting
Using health records and testing to study heart failure types
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
Sacramento, CaliforniaAges 30 years+ - NCT05934487Recruiting
Monitoring device trial for stable heart failure symptoms
This trial tests whether a wearable home monitoring system (myCordella™) can help people with moderate heart failure (NYHA class II or III) by tracking heart pressure and supporting follow-up care. It may help detect changes earlier so clinicians can adjust treatment sooner.
Phoenix, ArizonaAges 18 years+ - NCT06061549RecruitingPhase 1
Gene therapy for stiff heart failure (preserved EF)
This trial tests a one-time gene therapy for people with heart failure who still have normal pumping strength (preserved ejection fraction). It aims to improve how heart cells handle calcium, which may help the heart relax better and ease symptoms.
Durham, North CarolinaAges 50 years+ - NCT06081543Recruiting
Ketogenic vs. Mixed Diet for Heart Failure
This study compares a ketogenic (low-carb, high-fat) diet to a standard mixed diet in people with heart failure. It aims to see if the ketogenic diet can improve heart function and symptoms.
Columbus, OhioAges 18–80 - NCT06297707Recruiting
Aquatic strength training for chronic heart failure
This trial tests whether high-intensity resistance training in water can improve strength and function in people with chronic heart failure. It's designed for those who are stable on medication and not yet in a rehab program.
Cairo, DokkiAges 45–60 - NCT06313684Recruiting
Hybrid cardiac rehab for heart failure patients
This study tests a hybrid cardiac rehab program (both at the clinic and at home) for people with heart failure. It combines supervised exercise sessions with remote support to help improve your heart health and daily function.
SantiagoAges 18 years+ - NCT06455878Recruiting
Mobile app for weight loss in heart failure patients
This trial tests a mobile app that helps you track your diet to manage your weight. It is designed for people with heart failure who are overweight and have recently been in the hospital for their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06479876Recruiting
Home-based heart rehab for heart failure
This study tests a home-based cardiac rehabilitation program for people with heart failure. It aims to help you become more active and manage your condition safely at home.
Nashville, TennesseeAges 18 years+ - NCT06556485Recruiting
Early ablation for heart failure patients with heart pumps or on transplant list
This trial tests whether doing a catheter ablation early (before dangerous heart rhythms start) can help people with severe heart failure who need a heart transplant or already have an ICD. The goal is to see if this can improve outcomes.
Bad OeynhausenAges 18–99 - NCT06578520RecruitingPhase 4
Testing dapagliflozin for heart failure on dialysis
This trial tests whether adding dapagliflozin (a medication that helps protect the heart and kidneys) helps people with heart failure who are also on peritoneal dialysis. It may offer extra support for your heart and kidney health.
ValenciaAges 18 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06661876Recruiting
Heart radiation therapy for heart failure
This trial tests if a low dose of radiation to the heart can help people with advanced heart failure feel better and improve heart function. It is for patients whose heart failure is stable but severe, and who are already on the best medications.
LeuvenAges 18 years+ - NCT06675448Recruiting
Best practices for heart failure with leaky mitral valve
This trial compares two treatment approaches for people with heart failure and a leaky mitral valve (mitral regurgitation). It aims to find which strategy leads to better outcomes. You may be eligible if your heart function is reduced and you have symptoms despite standard treatments.
Falls Church, VirginiaAges 18–99 - NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT06783335Recruiting
Cordella sensor for chronic heart failure
This trial studies a small sensor placed in the lung artery to help manage chronic heart failure. It compares patients who get the sensor to those who receive standard care, to see if the sensor improves outcomes.
Naperville, IllinoisAges 18 years+ - NCT06831825RecruitingPhase 1
Gene therapy for heart failure recovery trial
This trial tests a gene therapy injected into the heart to help it recover after a previous heart attack. It may be an option for people with stable heart failure who are not eligible for standard procedures like stents or bypass surgery.
Houston, TexasAges 18–79 - NCT06884631Recruiting
Heart failure risk assessment with exercise test and kidney health
This study uses a special exercise test, along with heart and kidney measurements, to better predict risks for people with heart failure. It may help your doctors understand your condition and choose the best care for you.
Milan, ItalyAges 18 years+ - NCT06909682Recruiting
AI monitoring with wearables for chronic heart failure
This trial tests an AI system that uses wearable devices and mini-invasive tools to monitor people with chronic heart failure. The goal is to detect changes early and help manage the condition at home.
SalernoAges 19 years+ - NCT06961929Recruiting
Heat and Heart Failure Study
This study looks at how heat affects the body in people with stable heart failure compared to healthy volunteers. It may help researchers understand how to better manage heart failure in daily life.
Dallas, TexasAges 45 years+ - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT07023536Recruiting
Heart rehab program from home for chronic heart failure
This trial tests a cardiac telerehabilitation program for people with chronic heart failure. It is designed to see if doing rehab at home using digital tools helps improve health and quality of life.
SalernoAges 18 years+ - NCT07209098Recruiting
Heart failure study testing CCM therapy
This study tests a therapy called Cardiac Contractility Modulation (CCM) for people with heart failure. It uses a device to help the heart pump more strongly, and researchers compare it to standard care using patient records.
Marlton, New JerseyAges 18 years+ - NCT07247032Recruiting
Heart failure management with remote monitoring
This trial tests whether remote monitoring of your implanted heart device can help your doctors better manage your heart failure. It is for people with certain types of pacemakers or defibrillators who are willing to share their device data remotely.
ParisAges 18–85 - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+
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Common questions
- Are there clinical trials for heart failure nyha class iii?
- Yes. Clin2 currently lists 134 recruiting heart failure nyha class iii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure nyha class iii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure nyha class iii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.