Clinical trials
Invasive Mechanical Ventilation clinical trials
Below are recruiting invasive mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 130 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07098611Recruiting
New tool to predict readiness for breathing tube removal
This study tests a new scoring tool to help doctors decide when a patient on a breathing machine is ready to have the tube removed safely. It is for patients who are currently in the process of being weaned off the ventilator.
Punta ArenasAges 18–89 - NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT06754670Recruiting
How low phosphate affects breathing after ventilator use
This study looks at how low phosphate levels in the blood affect your ability to breathe on your own when coming off a ventilator. If you are already getting better and ready to start breathing without the machine, the results may help doctors understand and manage your recovery better.
BeijingAges 18 years+ - NCT05211661Recruiting
Study breathing muscle changes in people on a ventilator
This study looks at how the diaphragm (a key breathing muscle) changes during and after being on a breathing machine in the ICU. It may help researchers understand why breathing can get weaker after ventilation and how to measure it safely (including with MRI).
AachenAges 18–75 - NCT07372794Recruiting
Lung imaging-guided breathing therapy for patients on ventilators for weeks
This study tests whether using a special lung imaging technique called EIT can help guide breathing exercises and physical therapy for people who have been on a breathing machine for 21 days or more. The goal is to see if this approach helps your lungs work better and speeds up recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT02735707RecruitingPhase 3
Adaptive trial for severe pneumonia care in intensive care
This study tests ways to improve treatment for adults with severe pneumonia that lands them in the ICU, adjusting the plan as results come in. It may help your care team find better treatments for lung infection and breathing/heart support needs.
Jacksonville, FloridaAges 18 years+ - NCT06531005Recruiting
Checking breathing to predict when a breathing tube can be removed in the ICU
This study looks at how well current breathing measures predict a patient's readiness to have their breathing tube removed in the intensive care unit (ICU). It aims to make the decision to remove the tube safer and more accurate.
Altindağ, AnkaraAges 18 years+ - NCT06837402Enrolling by invitation
Non-invasive ventilation in Argentine ICUs: an observational study
This study looks at how non-invasive breathing support (like a mask or machine) is used in ICUs across Argentina. It helps doctors understand patterns of care so they can improve treatment for patients with breathing problems.
CABA, Buenos AiresAges 18 years+ - NCT06969443Recruiting
Studying rehab practices in the intensive care unit
This study watches how patients in the intensive care unit are helped to move and strengthen their muscles (rehabilitation) during their stay. It does not give any new treatment or medicine, but simply documents what usual care looks like for people who need a breathing tube for more than two days.
ParisAges 18 years+ - NCT06757166Recruiting
Non-invasive respiratory support for COVID-19 breathing failure
This study tests if non-invasive breathing support (like a mask or high-flow oxygen) can help hospitalized patients with low oxygen levels due to COVID-19, without needing a breathing tube. It aims to see how well it works and what risks it may have.
Rotterdam, South HollandAges 18 years+ - NCT07265882Recruiting
Bedside test for breathing tube patients
This trial uses a simple bedside test to evaluate patients who are on a breathing machine and not breathing on their own. It may help doctors better understand and manage acute respiratory failure.
Pavia, PaviaAges 18–90 - NCT05668637Recruiting
AI tool to support care decisions for ventilated adults
This study tests an artificial intelligence (AI) software that helps clinicians make care decisions for people who are on a breathing machine. It may help teams respond faster and more consistently when complex breathing support is needed.
Cleveland, OhioAges 18 years+ - NCT05785637Recruiting
Home sleep testing after starting noninvasive breathing support
This study checks breathing/sleep measurements done at home for people who recently started a machine that helps them breathe without an endotracheal tube. It may help the team confirm how well home monitoring works after hospital setup of this breathing support.
GarchesAges 18 years+ - NCT06421012Recruiting
Extra oxygen before breathing tube suctioning in the ICU
This study looks at whether giving extra oxygen before a breathing tube suctioning procedure (called tracheal aspiration) helps patients in the ICU who are on a breathing machine. It aims to make the procedure safer and more comfortable.
ParisAges 18 years+ - NCT06914336Recruiting
Liver ultrasound to check fluid buildup in ventilated patients
This trial uses an ultrasound of your liver to see if there is extra fluid or pressure in your veins that might make it harder to breathe. It may help doctors understand how to better manage the breathing machine for people who have been on it for more than a day.
BrestAges 18 years+ - NCT07326215Recruiting
A study of a device that removes carbon dioxide from the blood
This trial tests a device called PrismaLung+ that helps remove extra carbon dioxide from the blood of patients on breathing machines. It may help people whose lungs are struggling despite gentle ventilation settings.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06464224Recruiting
Breathing effort patterns in patients coming off the ventilator
This study observes how your breathing effort changes as doctors try to remove you from the breathing machine (ventilator). It helps understand why some patients have trouble breathing on their own after being on the ventilator.
Rio de JaneiroAges 18 years+ - NCT05492344Recruiting
Ultrasound-guided breathing support for severe lung failure
This study tests whether using an ultrasound scan to guide a breathing machine settings can improve care for people with moderate or severe ARDS, a serious lung condition. If you qualify, the team will compare the ultrasound-guided approach to standard ventilator care in the ICU.
BrusselsAges 18–100 - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT07596589RecruitingPhase 3
Remimazolam sedation for breathing-machine patients in ICU
This study tests whether a sedative medication called remimazolam helps patients on breathing machines (ventilators) in the ICU recover better and have fewer complications. You would receive this medication to keep you calm and comfortable while on the ventilator.
Nanjing, JiangsuAges 18 years+ - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT06790875Recruiting
Comparing two ventilator settings for lung health in ARDS
This study tests two methods of adjusting a ventilator to see which one may better protect the lungs of patients with ARDS. It will help doctors learn how to set the machine to reduce strain on the lungs.
Wuhan, HubeiAges 18–80 - NCT07245888Recruiting
Studying pneumonia in ventilated ICU patients
This study looks at different types of lung infections in ICU patients on breathing machines. By analyzing fluid from your lungs, researchers hope to better understand pneumonia and improve treatment.
LimogesAges 18 years+
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Common questions
- Are there clinical trials for invasive mechanical ventilation?
- Yes. Clin2 currently lists 130 recruiting invasive mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a invasive mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a invasive mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.