Clinical trials
Positive Pressure Ventilation clinical trials
Below are recruiting positive pressure ventilation clinical trials, each written for real people, not researchers. We’re tracking 75 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06430554Recruiting
Personalized ventilation for ARDS patients on breathing machines
This trial tests a personalized ventilation method that adjusts how the breathing machine delivers air based on your lung's air and blood flow match. It aims to improve breathing for people with moderate to severe ARDS who are already on a ventilator and will be placed on their stomach.
Nanjing, JiangsuAges 18–85 - NCT06939335RecruitingPhase 3
Testing a breathing method during CPR after cardiac arrest
This trial tests whether a specific breathing technique (PEEP) during CPR helps improve outcomes for adults who have a cardiac arrest outside the hospital and are being treated by emergency medical teams.
Ostend, West-FlandresAges 18 years+ - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT07603310Recruiting
PEEP levels in ARDS based on lung response
This study tests whether adjusting ventilator settings based on how well your lungs respond can improve oxygen and reduce damage in patients with moderate to severe ARDS, within the first 36 hours of diagnosis.
Rancagua, Región del Libertador General Bernardo O’HigginsAges 18 years+ - NCT07867730Recruiting
Breathing exercises help people on ventilators with stiff lungs
This study tests two breathing exercises, inspiratory muscle training and positive expiratory pressure, for people in the ICU on a breathing machine. It aims to see if these exercises can improve breathing and recovery for patients with restrictive lung disease.
IslamabadAges 18–60 - NCT07047092RecruitingPhase 3
CPAP vs. NIV for sleep apnea in COPD after breathing failure
This trial compares two breathing devices (CPAP and NIV) for people with both COPD and sleep apnea who recently needed breathing help in the hospital. The goal is to see which device works better at preventing future breathing emergencies.
ParisAges 18–84 - NCT07233304Recruiting
Lung opening procedure safety in children on breathing machines
This trial tests a lung opening procedure (alveolar recruitment maneuver) in children on a breathing machine to see if it's safe and helpful. It compares how well the procedure works with different machine settings.
Canuelas, Buenos AiresAges 1 month–14 years - NCT07193719RecruitingPhase 1/Phase 2
Personalized breathing support for kids after heart surgery
This study tests a personalized breathing technique to improve lung function and heart performance in children who have had heart surgery or are on ECMO. The goal is to find the best way to open up the lungs safely.
BerlinAges birth–18 years - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+ - NCT07130123Recruiting
Endotracheal suction during extubation in the ICU
This study compares different methods of suctioning the breathing tube during extubation (removal of the tube) in patients who have been on a ventilator for more than 48 hours. It aims to find the best way to clear the airway while taking the tube out.
Orléans, LoiretAges 18 years+ - NCT05612256Recruiting
Measuring breathing pressure in newborns using EIT
This study uses a painless electrical sensor method (EIT) to help find the best positive end-expiratory pressure setting for newborns on a ventilator. The goal is to improve how the ventilator supports breathing in the early days of life.
BaselAges birth–4 weeks - NCT06733168Recruiting
Electric imaging to guide breathing machine settings for ARDS
This trial tests whether using a special imaging technique (electrical impedance tomography) to set the breathing machine's pressure can improve oxygen levels and lung function in patients with moderate to severe ARDS, a serious lung condition.
HanoiAges 18 years+ - NCT04136717Recruiting
Test if FreeO2 helps keep oxygen levels in range
This study looks at whether adding FreeO2 can help keep your oxygen saturation (a measure of oxygen in the blood) within a target range while you use breathing support like NIV or CPAP. It may help reduce time spent either too low or too high in oxygen levels.
Québec, QuebecAges 18 years+ - NCT06611527Recruiting
Breathing therapy to improve lung function after heart surgery
This study tests a breathing treatment using mild air pressure after heart surgery to help your lungs work better and reduce complications. It may be an option for people at higher risk for lung problems or those with early breathing issues after surgery.
São Paulo, São PauloAges 18 years+ - NCT06442657Recruiting
Preventing bedsores in patients placed on their stomach
This trial tests a new way to prevent bedsores (pressure injuries) while patients lie on their stomachs for breathing support. It's for adults in the ICU with severe lung problems who are on a ventilator.
CaenAges 18–110 - NCT06448988Enrolling by invitation
Lung function in two surgical positions
This study measures how well your lungs work while you are lying on your back versus in the side-lying park-bench position during brain or spine surgery. It aims to help doctors understand which position is easier for you to breathe in.
RomeAges 18 years+ - NCT05958563Recruiting
CPAP may prevent COPD flare-ups in COPD-OSA overlap
This study tests whether using continuous positive airway pressure (CPAP) can reduce acute COPD flare-ups in people who also have sleep apnea. It may help by improving breathing during sleep and lowering the chance of worsening lung symptoms.
AngersAges 40 years+ - NCT05224323Recruiting
Testing a lung opening breathing pattern in early ARDS
This study looks at a specific breathing event (“avalanche phenomenon”) when the lungs are opened in people with early, moderate-to-severe ARDS. The goal is to understand what’s happening in the lungs and whether it can guide better care.
PoitiersAges 18 years+ - NCT07060833Recruiting
Sound to check breathing pressure in premature babies on bubble CPAP
This study is testing whether the sound of the bubbles in a CPAP machine can tell doctors how much pressure is being delivered to a premature baby's lungs. If it works, this could help doctors make sure babies are getting the right amount of breathing support without extra procedures.
Montreal, QuebecAges 6 months–7 months - NCT07490925Recruiting
Breathing Machine Strategy to Protect the Heart in ARDS
This trial tests a special breathing machine strategy that uses pressure measurements from a small tube in your esophagus (food pipe) to protect your heart's right side while treating ARDS caused by pneumonia. It may help if you have severe lung failure and need a ventilator.
BeijingAges 18 years+ - NCT06703814Recruiting
Protective breathing support during robot surgery
This trial tests a special way of breathing support during robot-assisted surgery to protect your lungs. It's for people who are at higher risk of lung problems after surgery.
Innsbruck, TyrolAges 18 years+ - NCT05098717Recruiting
PEEP settings guided by lung pressure in pulmonary fibrosis
This trial tests whether using lung-pressure measurements to adjust ventilator PEEP (a breathing-support setting that keeps airways open) can help people with pulmonary fibrosis who are on a breathing machine for acute respiratory failure. It may improve breathing comfort and oxygenation by finding the best PEEP level for you.
ModenaAges 18–90 - NCT06684119Recruiting
Testing best breathing tube pressure for children on a ventilator
This trial uses a special imaging tool (EIT) to find the best air pressure in the breathing tube for children on a ventilator. It aims to improve lung function in children with a lung condition called PARDS.
Los Angeles, CaliforniaAges birth–18 years - NCT07673250Enrolling by invitation
Personalized breathing settings for ECMO patients
This study tests whether personalized breathing machine settings can improve outcomes for people on ECMO (a heart-lung support machine). It is designed for patients who have had or are waiting for a lung or heart transplant.
La Jolla, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for positive pressure ventilation?
- Yes. Clin2 currently lists 75 recruiting positive pressure ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a positive pressure ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a positive pressure ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.