Clinical trials
Transplant; Failure, Heart clinical trials
Below are recruiting transplant; failure, heart clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04438213RecruitingPhase 2
Ertugliflozin for chronic heart failure with added urine testing
This Phase 2 trial studies whether the medication ertugliflozin can help people with chronic heart failure. You would be asked to follow a set treatment plan and complete repeated urine (and other) testing to see how your body responds.
New Haven, ConnecticutAges 18 years+ - NCT06149195Enrolling by invitation
Heart scan for managing heart failure
This trial tests a special heart scan (18F-MFBG) to see if it can help doctors better manage heart failure. You may qualify if you have chronic heart failure with a weak heart pump and are planning to get a defibrillator.
Chengdu, SichuanAges 18–80 - NCT06105580Recruiting
Pacing methods for heart failure with wide QRS
This trial compares two ways to pace the heart in people with heart failure and a wide QRS (a sign the heart's electrical signals are slowed). The goal is to see which method better reduces the risks of death, heart failure hospitalization, or needing a heart transplant.
BarcelonaAges 18 years+ - NCT06081543Recruiting
Ketogenic vs. Mixed Diet for Heart Failure
This study compares a ketogenic (low-carb, high-fat) diet to a standard mixed diet in people with heart failure. It aims to see if the ketogenic diet can improve heart function and symptoms.
Columbus, OhioAges 18–80 - NCT05934487Recruiting
Monitoring device trial for stable heart failure symptoms
This trial tests whether a wearable home monitoring system (myCordella™) can help people with moderate heart failure (NYHA class II or III) by tracking heart pressure and supporting follow-up care. It may help detect changes earlier so clinicians can adjust treatment sooner.
Phoenix, ArizonaAges 18 years+ - NCT05627440Recruiting
Protein diet program to improve muscle strength in heart failure
This trial tests whether adding dietary protein can help skeletal muscles recover and function better in people living with heart failure. It may help with strength, muscle wasting, and overall ability to do daily activities.
Boston, MassachusettsAges 18–100 - NCT05873634Recruiting
Using health records and testing to study heart failure types
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
Sacramento, CaliforniaAges 30 years+ - NCT05873881RecruitingPhase 3
Colchicine and vitamin B1 for ischemic heart failure
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Hamilton, OntarioAges 45 years+ - NCT04970888Recruiting
Exercise program to improve thinking and brain blood flow in heart failure
This trial tests whether doing a combined mental (cognitive) and physical exercise program can improve thinking and how well blood flows to the brain in people with chronic heart failure. It may help by strengthening both brain function and physical capacity while your heart condition stays stable.
Montreal, QuebecAges 50 years+ - NCT05677100Recruiting
Aortix device for acute heart failure
This trial is testing a small pump placed in the aorta to help the kidneys remove extra fluid when standard IV diuretics aren't working well enough for severe heart failure. It may help you if you're hospitalized and still very congested (swollen, fluid buildup) despite strong water pills.
Phoenix, ArizonaAges 21 years+ - NCT05647213RecruitingPhase 1
Skin biopsy study of stem-cell therapy for congenital heart disease
This early study takes a small skin sample to make a personalized type of heart stem cells in the future. It is testing whether this approach is safe and feasible for people with complex single-chamber congenital heart disease and advanced heart failure.
Rochester, MinnesotaAges 18–40 - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Los Angeles, CaliforniaAges Up to 21 years - NCT05568069Recruiting
Study of defibrillator implants for non-ischemic weak heart
This study looks at whether implantable defibrillators can reduce dangerous heart rhythms in people with non-ischemic cardiomyopathy (heart weakness not caused by blocked heart arteries), a heart scar, and very low pumping strength despite best treatment. It compares different approaches to choosing which patients should receive these devices.
High Wycombe, BuckinghamshireAges 18 years+ - NCT05451979Recruiting
Exercise training at home for kids after heart transplant
This trial tests a home-based, short bursts exercise program (HIIT using the MedBIKE™ system) for children who had a heart transplant at least 6 months ago. It may help improve fitness and safety after transplant, while checking which kids can participate without heart rhythm or symptom problems.
Edmonton, AlbertaAges 10–18 - NCT05285878Enrolling by invitationPhase 2
Fingolimod to protect kidney function after kidney transplant
This trial tests whether fingolimod can reduce kidney scarring and preserve kidney function after a new kidney transplant. It focuses on people who are in the early period after transplant who may be at risk for scarring in the kidney.
Houston, TexasAges 18–65 - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT04848844Recruiting
Congenital heart disease transplant registry study for adults
This study collects and shares anonymous information about adults being considered for a heart transplant because of a congenital (from birth) heart problem or an inherited heart muscle condition. The goal is to better understand these patients and support research that may improve care.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04656080Recruiting
Test heart and lung exercise capacity after transplant
This study uses a treadmill or stationary bike test to measure how well your heart and lungs work after a heart transplant. It may help researchers see whether this type of testing is safe and useful in transplant follow-up.
Dallas, TexasAges 18 years+ - NCT04493385Recruiting
Heart transplant after a hepatitis C–positive donor
This trial follows people who receive a heart from a donor whose blood tested positive for hepatitis C. It also includes people getting a heart transplant again, and it aims to learn about outcomes and safety for these specific transplant situations.
Dallas, TexasAges 18 years+ - NCT04180085RecruitingPhase 2
Belatacept to protect kidneys in heart transplant patients
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
BordeauxAges 18 years+ - NCT04066127Enrolling by invitation
Heart transplant study comparing two types of heart storage
This trial tests whether using a different method to store a donated heart before transplant improves outcomes. It compares “non-ischemic preservation” versus standard cold storage for people getting a new heart.
Lund, Skåne CountyAges 18 years+ - NCT03586336Recruiting
Remote lung fluid monitoring to guide heart failure treatment
This study tests a wearable vest that measures fluid in your lungs to help doctors adjust water-pill treatments for heart failure. It aims to reduce hospital stay and improve recovery.
San Francisco, CaliforniaAges 18 years+ - NCT03103932Recruiting
Blood test–guided discharge for people hospitalized with heart failure
This trial checks whether using a blood test (a “biomarker”) can help doctors decide when it’s safe to send people home after a hospital stay for worsening heart failure. It may help reduce avoidable readmissions while keeping you safe.
Ottawa, OntarioAges 18 years+ - NCT03102125RecruitingPhase 4
Testing causes of heart transplant graft problems with scans
This study looks at why heart transplant “grafts” can start to malfunction again after transplant. If you qualify, you may undergo MRI and related heart testing to help researchers find ways to detect or understand graft dysfunction.
La Jolla, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for transplant; failure, heart?
- Yes. Clin2 currently lists 266 recruiting transplant; failure, heart studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transplant; failure, heart trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transplant; failure, heart trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.