Clinical trials
Traumatic Brain Injury (TBI) Patients clinical trials
Below are recruiting traumatic brain injury (tbi) patients clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07625995RecruitingPhase 2
Fluid management strategies for traumatic brain injury patients
This study tests two different approaches to managing fluids given to brain injury patients in the ICU—one more restrictive and one more liberal—to see which is safer and more effective. The goal is to find the best balance that protects the brain while supporting overall health.
BrusselsAges 18 years+ - NCT07296783Enrolling by invitation
Tracking recovery in older adults with traumatic brain injury
This study observes older adults (65+) who have had a recent head injury to understand how they recover over time. It may help improve care for seniors with brain trauma.
San Francisco, CaliforniaAges 65 years+ - NCT06981897Enrolling by invitation
Early cognitive rehab for moderate brain injury recovery
This trial tests whether starting cognitive rehabilitation early after a moderate traumatic brain injury helps improve thinking, memory, and daily function. If you're an adult with a moderate brain injury who is medically stable, this study may help you regain skills faster.
Cairo, ManialAges 18 years+ - NCT06817837Enrolling by invitation
Can hypnosis help adults with brain injury?
This study tests if hypnosis can help adults with stroke or traumatic brain injury who have symptoms like anxiety, trouble sleeping, pain, or behavior issues. Researchers want to see if it's a feasible and useful addition to usual care.
Tinlot, LiègeAges 18 years+ - NCT05929833Enrolling by invitation
Brain injury education program for recovery at home
This study tests a recovery-focused brain injury education and support program for people with traumatic brain injury (TBI) who plan to go home after hospital stay. If you qualify, you and a caregiver/friend may get training and therapy support aimed at improving recovery.
Durham, North CarolinaAges 18 years+ - NCT05786729Enrolling by invitationPhase 1/Phase 2
Aerobic exercise program after traumatic brain injury
This trial tests whether a supervised aerobic exercise plan is safe and helpful for people recovering from traumatic brain injury (TBI). It may help improve physical fitness and functioning through regular walking and aerobic training.
Bakersfield, CaliforniaAges 18–60 - NCT05616910Enrolling by invitationPhase 2
Inhaled nitric oxide for microvascular problems after brain injury
This Phase 2 study tests whether inhaled nitric oxide can improve tiny blood-flow problems in the brain after traumatic brain injury. If you qualify, you may receive inhaled nitric oxide and be monitored for safety and recovery.
Philadelphia, PennsylvaniaAges 18–75 - NCT03502967Enrolling by invitationEarly Phase 1
Hyperpolarized carbon-13 brain scan for recent traumatic brain injury
This early study tests a special brain imaging scan that looks at brain metabolism after a recent concussion/traumatic brain injury (TBI). It may help researchers understand what’s happening in the brain soon after injury.
Dallas, TexasAges 18–60 - NCT06790095Enrolling by invitationPhase 2
Testing Cyclosporine for Moderate to Severe Brain Injury
This study tests a drug called cyclosporine to see if it can help people with moderate to severe traumatic brain injury. You may be eligible if you have a brain injury seen on CT and can start treatment within 24 hours.
San Francisco, CaliforniaAges 18–65 - NCT07345481Recruiting
Learning new connections in brain injury
This study tests whether people with an acquired brain injury can learn new connections between symbols and words using a computer-based learning method. The goal is to see if this approach can help with cognitive rehabilitation.
Arnhem, GelderlandAges 18–75 - NCT05628207Recruiting
Test of an acceptable care-scaling plan for people with brain injury
This trial looks at a care approach to see if it is acceptable and workable for adults admitted to the hospital with a traumatic brain injury. It may help improve how care is scaled and delivered after TBI.
Minneapolis, MinnesotaAges 18 years+ - NCT05323149RecruitingPhase 3
Tranexamic acid for non-penetrating brain injury after trauma
This Phase 3 study tests whether tranexamic acid can improve outcomes after traumatic brain injury. It may help by reducing bleeding and related damage soon after the injury in adults with mild to moderate cases.
Asyut, AssuitAges 18–65 - NCT05933629Recruiting
Training mental health providers to deliver an online TBI group program
This study helps test whether community mental health clinicians can learn and successfully deliver an online emotion-regulation group program for people with traumatic brain injury (TBI). It may help improve access to structured support when in-person group care is hard to reach.
New York, New YorkAges 18 years+ - NCT03694626Recruiting
Test a light-response study to measure and track light sensitivity
This study aims to objectively measure how your pupils respond to light and how your eye muscles react using recording tests. It may help confirm the cause of light sensitivity (especially after a brain injury) and better track how it responds to care.
Iowa City, IowaAges 18–80 - NCT05566431Recruiting
Check monitoring for high brain pressure after child head injury
This study looks at a way of measuring and responding to high pressure inside the brain in children after a non-penetrating head injury. It may help doctors decide which monitoring approach works best for children who are very sick right after injury or become worse quickly.
Seattle, WashingtonAges 1–12 - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+ - NCT06381674Recruiting
Wearable tech for balance rehab after concussion
This study tests whether a wearable device can help people with balance and vision problems after a mild concussion. You will use the device to guide your own exercises and help improve your recovery.
Portland, OregonAges 18–60 - NCT06511804Recruiting
Blood vessel function and brain blood flow in neurocritical patients
This study looks at how blood vessel function relates to brain blood flow in patients in intensive care with brain injuries or conditions. It aims to find better ways to monitor patients using non-invasive tools.
Louisville, KentuckyAges 18–100 - NCT06920784Recruiting
Prismatic glasses therapy for brain injury rehabilitation
This trial tests whether wearing special prismatic glasses during cognitive exercises can help people recovering from a traumatic brain injury. It is designed for patients who are still in the early stages of recovery and have a certain level of consciousness and attention.
BariAges 18 years+ - NCT07176936Recruiting
Can ear stimulation improve hearing in noise?
This study tests whether a gentle, noninvasive ear stimulation device can help people hear speech better in noisy places. It is for people who have had a traumatic brain injury or those with normal hearing.
Gainesville, FloridaAges 25–55 - NCT07311486Recruiting
Blood test for better care after mild head injury
This study uses a blood test to help doctors better understand and manage mild traumatic brain injury (concussion). If you had a mild head injury in the past 12 hours and have certain symptoms, researchers want to check if a new blood-based approach can improve care.
Madrid, MadridAges 18 years+ - NCT06819904Recruiting
Combined talk therapy and balance rehab for mild TBI
This trial tests a new type of therapy that combines acceptance and commitment therapy (a counseling approach) with vestibular rehabilitation (exercises for balance and dizziness). It's designed for people with mild traumatic brain injury who still have symptoms like dizziness, anxiety, or memory problems.
Pittsburgh, PennsylvaniaAges 18–49 - NCT06433622Enrolling by invitation
Platelet transfusion for severe brain injury on blood thinners
This trial tests whether giving a platelet transfusion to patients with severe traumatic brain injury who are on antiplatelet medication can improve how well their blood clots. You may qualify if you have a serious brain bleed and are taking a medication like aspirin or clopidogrel.
Lancaster, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for traumatic brain injury (tbi) patients?
- Yes. Clin2 currently lists 95 recruiting traumatic brain injury (tbi) patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a traumatic brain injury (tbi) patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a traumatic brain injury (tbi) patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.