Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07125833Recruiting
Cold therapy for shoulder replacement pain
This trial tests if freezing a nerve near the shoulder before surgery can reduce pain after a reverse total shoulder replacement. It may help you recover with less discomfort.
Rockwall, TexasAges 30–85 - NCT07123805Recruiting
Acupuncture for knee replacement recovery
This study tests if adding acupuncture before and after knee replacement surgery helps reduce pain and improve recovery. It may be an option for people having planned knee replacement for osteoarthritis.
Pavia, PaviaAges 18 years+ - NCT07120659Recruiting
Comparing vacuum and tactile massage for chronic neck pain
This study compares two types of massage (vacuum massage and tactile massage) to see which one works better for people with long-term neck pain. If you have had neck pain for at least 3 months, you may be able to join.
Tromsø, TromsAges 21–75 - NCT07120997Recruiting
Prunes to prevent bone loss during perimenopause
This study tests whether eating prunes every day can help prevent bone loss in women going through perimenopause. If you are between 44 and 55, not severely obese, and have irregular periods, you may be able to join.
University Park, PennsylvaniaAges 44–55 - NCT07119255Recruiting
PRP acupuncture for long-term neck pain from muscle tightness
This study tests whether a treatment called platelet-rich plasma (PRP) acupuncture — using your own blood proteins — can reduce chronic neck pain caused by a common muscle condition. It may be a good option if you have had neck pain for months and want a non-surgical approach.
JakartaAges 18–59 - NCT07121556Recruiting
Fat tissue vs fat tissue plus gel for knee osteoarthritis
This trial compares two injections for knee arthritis: one uses your own fat tissue, the other adds a lubricating gel. Researchers want to see if the combination helps pain and function more than fat tissue alone.
BolognaAges 18–75 - NCT07122323Enrolling by invitation
Robot-assisted hip replacement for Legg-Calve-Perthes disease
This trial compares robot-assisted total hip replacement to the usual surgery for people with Legg-Calve-Perthes disease. It aims to see if the robotic arm helps the surgery go more smoothly.
Hangzhou, ZhejiangAges 18–80 - NCT06965985Recruiting
Comparing two hand therapies for tennis elbow
This study compares two gentle hand-on treatments (mobilization and myofascial release) for tennis elbow. It aims to see which one works better for reducing pain and improving function.
Konya, SelçukluAges 18–65 - NCT07109466Recruiting
Virtual balance training to reduce falls in older veterans
This study tests a virtual exercise program that strengthens muscles around your hips to help you keep your balance and reduce falls. It is done at home using video visits, so you don't need to travel.
Baltimore, MarylandAges 65 years+ - NCT07107581Enrolling by invitation
Exactech knee replacement follow-up study
This study is following patients who have or will receive an Exactech total knee replacement. It looks at how well the knee works over time and helps doctors understand long-term results.
DeLand, FloridaAges 18 years+ - NCT05232604Recruiting
Exercise vs local pain exercises for jaw and neck pain
This study compares two types of treatment: aerobic exercise versus exercises aimed at the painful jaw/neck area. It may help people with long-term jaw and neck pain by testing which approach improves pain and function.
Osnabrück, Lower SaxonyAges 18–60 - NCT07108920Recruiting
Balance and Botox for Stiff Knee Gait
This study tests whether botulinum toxin (Botox) injections into the rectus femoris thigh muscle can improve balance and walking in people with a stiff knee gait (a common problem after stroke, brain injury, or multiple sclerosis).
Héricourt, Nord Franche-ComtéAges 18 years+ - NCT07112807Recruiting
Shoulder blade exercise study: Sphere vs. Blade
This study compares two types of exercise (ShoulderSphere and Bodyblade) to improve shoulder blade movement. It is for people who have scapular dyskinesia but no current or recent shoulder pain.
AnkaraAges 18–25 - NCT07106931Recruiting
Early arthritis: identifying the cause quickly
This trial aims to quickly identify the type of arthritis in people with recent joint swelling (less than 12 weeks). It may help doctors start the right treatment sooner.
OsloAges 18 years+ - NCT07111286Recruiting
Imagining movements to help chronic low back pain
This trial tests whether imagining movements (motor imagery) can help improve daily function and reduce pain in people with chronic low back pain. You will participate in a rehabilitation program, and if you are in the motor imagery group, you will also practice mentally rehearsing specific movements.
DijonAges 18 years+ - NCT07111494RecruitingPhase 4
GLP-1 medication for psoriatic arthritis outcomes
This study tests if adding a GLP-1 medication (a type of drug that helps with weight and blood sugar) to your usual psoriatic arthritis treatment can improve your joint and skin symptoms. It is for people with psoriatic arthritis who have not yet achieved good control of their disease and have a higher body weight.
Milwaukee, WisconsinAges 18 years+ - NCT07111325RecruitingPhase 1/Phase 2
iEVs injection for tennis elbow
This trial tests an injection called iEVs for people with tennis elbow (lateral epicondylitis) that hasn't gotten better with physical therapy or anti-inflammatory drugs. It aims to see if the treatment is safe and helps reduce pain.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07111858Recruiting
Pavlik harness vs monitoring for hip dysplasia in babies
This trial compares using a soft brace (Pavlik harness) versus simply monitoring for babies diagnosed with a certain type of hip condition (Graf type 2b or 2c). Researchers want to see which approach leads to better hip development and avoids the need for more intensive treatment.
Royal Tunbridge WellsAges birth–4 months - NCT07115225Recruiting
Shoulder tests for athletes after a dislocation
This study tests a set of physical tests to see how well they measure shoulder function in people who have had a shoulder dislocation and plan to return to sports. It may help you understand if you are ready to go back to your sport safely.
AntwerpAges 16–55 - NCT07112508Recruiting
A dashboard to help physiotherapists improve care
This trial tests a new online dashboard that helps physiotherapists see how their treatment choices compare to others. It aims to improve care for people with muscle, bone, or joint problems in primary care.
LondonAges 18 years+ - NCT07113860Recruiting
Aging expectations and walking program for older couples
This study tests whether a program that combines gentle walking with exercises to rethink aging stereotypes can help couples 65 and older feel better and stay active. If you and your partner live in Barcelona, have internet access, and are willing to try a new approach, you may be eligible.
Barcelona, CataloniaAges 65 years+ - NCT07112742Enrolling by invitation
Laser and exercise for thumb arthritis
This study tests if a special laser treatment plus hand exercises can reduce pain and improve function in people with thumb arthritis. It compares the laser to a placebo laser, so you won't know which group you're in.
KayseriAges 45–75 - NCT07108400Recruiting
Combination therapy for hip osteoarthritis pain and function
This trial tests if combining ultrasound-guided hyaluronic acid injections with laser therapy and rehabilitation can improve hip function and reduce pain in people with hip osteoarthritis. It may be an option if you have moderate hip pain and are not currently taking anti-inflammatory medications.
Catanzaro, CZAges 18–85 - NCT07113405Recruiting
Tea extract and knee strength after downhill jogging
This study tests whether taking a tea extract can help your knee muscles recover faster after a downhill jog. It compares the tea to a placebo to see if it reduces muscle soreness or weakness.
Fribourg, Canton of FribourgAges 18–40
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.