Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06755697Recruiting
Comparing injection methods for knee osteoarthritis
This trial compares two ways to give dextrose injections for knee osteoarthritis: one into the joint space and one guided by MRI into the tissues around the knee. It aims to see which approach works better for pain and function.
TaipeiAges 45–80 - NCT06756633Recruiting
Breathing and movement study for neuromuscular disease
This study looks at breathing, chest and belly movement, and exercise ability in people with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy, as well as healthy people. The goal is to compare these functions to help understand how these diseases affect the body.
Ankara, ÇankayaAges 5–15 - NCT06758050Recruiting
Core exercises for front knee pain
This study tests whether doing core exercises can help reduce knee pain in people with patellofemoral pain syndrome—pain at the front of the knee that comes on gradually. It is meant for young adults with a healthy weight who have had this type of knee pain for more than 3 months.
GizaAges 18–35 - NCT06758817Recruiting
Nutrition, gut health, and rheumatoid arthritis study
This trial tests if a specific diet can improve your rheumatoid arthritis symptoms by affecting your gut bacteria. You may be eligible if you have active RA and are willing to follow a special meal plan for several weeks.
Lisbon, PortugalAges 18 years+ - NCT06760884Recruiting
Pregnancy and jaw function study
This study looks at jaw joint function, oral habits, and pain in pregnant and non-pregnant women. It aims to understand how pregnancy might affect these issues.
TrabzonAges 18–45 - NCT06762171Recruiting
Knee arthritis treatment for inner and front knee pain
This trial tests a treatment for people with knee arthritis affecting the inner and front parts of the knee. It aims to help relieve pain and improve function without needing a full knee replacement.
Sohag, Sohag GovernorateAges 35–60 - NCT06762730RecruitingPhase 4
Zoledronic acid to prevent bone loss from HIV treatment
This trial tests if zoledronic acid, a drug that strengthens bones, can prevent bone loss caused by starting HIV treatment. It is for people newly diagnosed with HIV who have not yet taken any HIV medication.
HaifaAges 18 years+ - NCT06763419Recruiting
Light therapy for jaw joint pain
This trial tests if a non-invasive light therapy (photobiomodulation) can reduce pain and clicking in the jaw joint. It may help people with jaw pain caused by muscle tension or joint issues.
AlexandriaAges 20–40 - NCT06763601Recruiting
Shoulder treatment for frozen shoulder
This trial tests a new shoulder exercise method for frozen shoulder. If you are between 40–65 years old and have been diagnosed with frozen shoulder, you may be able to join.
AjmanAges 40–65 - NCT06763679Recruiting
Comparing two therapies for frozen shoulder pain
This trial tests whether adding a specific joint mobilization technique to a standard muscle-relaxing method works better for people with frozen shoulder. It aims to help improve shoulder movement and reduce pain.
Lahore, Punjab ProvinceAges 50–60 - NCT06764693Recruiting
Study on treatment with Risankizumab for psoriatic arthritis
This study tests how well a medicine called Risankizumab works for people with psoriatic arthritis. It is for adults who have had symptoms for at least 6 months and have not had enough help from at least one other arthritis medicine.
Quilmes, Buenos AiresAges 18–75 - NCT06764654Recruiting
Comparing two guided surgery methods for back jaw implants
This study compares two types of guided surgery methods for placing dental implants in the back of the jaw (where there are missing teeth). It aims to find which technique works better for patients who need implants in that area.
Alicante, AlicanteAges 18 years+ - NCT06766448Recruiting
Physical therapy for frozen shoulder
This trial tests if a special rehabilitation program helps people with frozen shoulder (adhesive capsulitis). It aims to improve shoulder movement and reduce pain.
RabatAges 18 years+ - NCT06767150RecruitingPhase 4
Bone treatment after stopping denosumab for osteoporosis
This trial tests whether giving zoledronic acid (a bone-strengthening infusion) right after stopping denosumab can help prevent bone loss in women with post-menopausal osteoporosis. It may be a good option if you have finished at least 2 years of denosumab and your doctor says it's safe to stop.
AmiensAges 18 years+ - NCT06767631Recruiting
Muscle and nerve changes after botox for stroke foot tightness
This study looks at how botulinum toxin (botox) injections affect the muscles, tendons, and nerves in the lower leg of people who have had a stroke and have a tight, twisted foot (equinovarus). It aims to understand these changes to improve future treatments.
LeuvenAges 40–60 - NCT06769386Recruiting
Muscle Oxygen in Rheumatoid Arthritis
This study looks at how muscles use oxygen in people with rheumatoid arthritis. You will do some exercise tests to measure your muscle oxygen levels, which may help doctors understand how the disease affects your muscles.
Kırşehir, MerkezAges 18–65 - NCT06769633RecruitingPhase 2
Study of givinostat in young boys with Duchenne muscular dystrophy
This trial tests an experimental drug called givinostat in boys ages 2 to under 6 years with Duchenne muscular dystrophy (DMD). The study looks at how the drug works in the body and if it is safe, with the goal of finding new treatment options for young children.
BrusselsAges 2–6 - NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Taipei, TaiwanAges 20–75 - NCT06773169Recruiting
Testing an app for self-managing chronic conditions
This study tests a smartphone or computer app designed to help people with long-term health conditions like arthritis, heart disease, or stroke manage their own recovery. The goal is to see if using the app improves daily living and reduces disability.
Hamilton, OntarioAges 44–75 - NCT06773676Recruiting
Home laser device study for knee osteoarthritis relief
This study tests whether using a laser device at home can help reduce knee pain and improve function in people with knee osteoarthritis. You would use the device yourself over several weeks to see if it eases your symptoms.
Ashkelon, Southern DistrictAges 50–90 - NCT06773988Recruiting
Long-term monitoring of breathing support at home for Duchenne patients
This study follows adults with Duchenne muscular dystrophy who use a breathing machine (non-invasive ventilation or NIV) at home. It aims to track their health over time to improve care.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06775262Recruiting
chronic fatigue in internal medicine patients
This study looks at people with chronic fatigue who saw a doctor but no physical cause was found. It aims to understand their experiences better.
Almere Stad, FlevolandAges 18 years+ - NCT06775704Recruiting
Studying outcomes of the ROMAX hip resurfacing system
This study tracks how well the ROMAX hip resurfacing system works over time, focusing on patient recovery and X-ray results. It is designed for adults who need hip resurfacing and are generally healthy enough for surgery.
LilleAges 18–65 - NCT06776003Recruiting
Mobility after vertebroplasty vs sham for spine fractures from osteoporosis
This trial compares a procedure called vertebroplasty (injecting bone cement into the broken bone) with a sham (fake) procedure to see how it affects your ability to move and be active. It's for people with recent painful spinal fractures caused by weak bones (osteoporosis).
KoldingAges 50 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.