Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07403188Recruiting
Long-Term Follow-Up Study for KYV-101 Participants
This long-term follow-up study checks on the health and safety of people who have already received the experimental cell therapy KYV-101 in a previous clinical trial. It is a way for them to be monitored over time without any additional treatments.
Denver, ColoradoAges 18 years+ - NCT07404618Recruiting
Video pain relief study for older adults
This study tests a video program to help older adults with ongoing muscle or joint pain learn skills to manage pain and improve daily life. It may be a good fit if pain has been bothering you most days for at least 3 months and gets in the way of your normal activities.
Providence, Rhode IslandAges 55 years+ - NCT07404891Recruiting
Study of ALT001 for knee osteoarthritis pain
This study tests whether a new medicine (ALT001) can safely reduce knee pain from osteoarthritis. If you join, you would stop your current pain medicines and take the study drug or a placebo for a set time, while being closely monitored.
Wuhan, HubeiAges 50–75 - NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT07408024RecruitingPhase 2
TollB-001 tablets for moderate to severe rheumatoid arthritis
This trial tests an experimental tablet, TollB-001, for people with moderate to severe rheumatoid arthritis who have not responded well to standard treatments. The goal is to see if the drug is safe and effective.
Bengbu, AnhuiAges 18–70 - NCT07409142Recruiting
BetterLife FSHD health and research platform
This study creates a patient-driven health and research platform for people with FSHD. It aims to collect information to better understand the condition and improve future research and care.
Randolph, MassachusettsAges 1 year+ - NCT07409818Recruiting
Shoulder calcific tendinitis treatment study
This trial tests a new way to classify calcium deposits in the shoulder tendon using MRI, which may help doctors choose the best treatment. It is for people who are having surgery for this condition.
Istanbul, ZeytinburnuAges Any age - NCT07412782Recruiting
REMS bone scan study for children with bone conditions
This study uses a new ultrasound technology called REMS to check bone health in children aged 5 to 18 who have conditions that weaken bones. It may help find low bone density without radiation.
Florence, TuscanyAges 5–18 - NCT07413302Recruiting
Predicting recovery after back surgery for leg weakness
This study looks at which factors before surgery help predict how well leg weakness improves after a single-level microdiskectomy (minimally invasive back surgery for a slipped disk). It may help you understand what to expect if you are having this procedure.
KavalaAges 18 years+ - NCT07413341RecruitingPhase 1
Study of new drug TI-0032-III for hard-to-treat autoimmune diseases
This early-phase trial tests a new drug called TI-0032-III for people with several autoimmune diseases that haven't gotten better with standard treatments. It aims to see if the drug can safely reduce disease activity and offer a new option for people who have few choices left.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07415837Recruiting
Studying a molecule in muscle diseases and healthy people
This study looks at a molecule called miR-1 in the blood to see if it can help understand muscle diseases. Researchers will compare levels in people with certain muscle conditions and in healthy volunteers.
Clermont-FerrandAges 2 years+ - NCT07415967Recruiting
Dual-task exercise for rotator cuff shoulder pain
This study tests an exercise program that combines shoulder movements with mental tasks (like counting or naming things) to improve pain and function. It is for people with ongoing shoulder pain from common rotator cuff problems.
IstanbulAges 18–65 - NCT07416656Recruiting
Checking blood sugar test accuracy for arthritis patients on sulfasalazine
This study checks if the medicine sulfasalazine affects a blood sugar test (HbA1c) in people with inflammatory arthritis. If you have arthritis, take sulfasalazine, and have higher blood sugar or diabetes, this trial may help understand your glucose levels.
Silkeborg, Central JutlandAges 18 years+ - NCT07416916RecruitingPhase 4
Comparing two ways to inject steroids for frozen shoulder
This trial compares two injection methods for frozen shoulder: one directly into the shoulder joint and one into the buttock muscle. It aims to see which works better for pain and movement.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07419269Recruiting
Comparing donor vs. patient bone grafts for jawbone repair
This trial tests whether donated (allogenic) bone blocks work as well as your own bone to rebuild the jaw so dental implants can be placed. It's for people missing 1-4 teeth where the bone ridge is too thin.
Graz, StyriaAges 18 years+ - NCT07419451Recruiting
Bone health and health knowledge study for older adults
This study looks at how much older adults know about osteoporosis and their overall health understanding. It aims to help improve education and awareness about bone health in aging.
Balıkesir, BandırmaAges 65 years+ - NCT07421713Recruiting
AI and chest x-rays to screen for osteoporosis
This trial tests if an AI software can use a chest x-ray to screen for osteoporosis, compared to the standard DXA bone density scan. It may offer a faster, simpler way to check bone health in people 50 and older.
RotterdamAges 50 years+ - NCT07421752Recruiting
Robot accuracy test in spinal surgery
This trial tests how accurately a robotic system helps place screws in the spine during surgery. It may benefit people who need spinal surgery that involves inserting pedicle screws.
AmiensAges 5 years+ - NCT07422454Recruiting
Database study on facial and skull development in children
This study is building a database of medical information and images from children with certain conditions affecting the face and skull, such as craniosynostosis, achondroplasia, and osteogenesis imperfecta. The goal is to better understand these conditions and improve future care.
ParisAges Any age - NCT07422714Recruiting
Wearable device system for frozen shoulder rehab
This trial tests a wearable device that guides you through exercises to help recover from frozen shoulder. It is designed for people in the 'frozen' phase of the condition.
BeijingAges 40–60 - NCT07423026Recruiting
Remote study using technology to track DMD in young boys
This study uses remote technology, like apps or wearable devices, to monitor motor skills and development in boys with Duchenne muscular dystrophy (DMD). It aims to find better ways to measure how the disease progresses over time without requiring frequent clinic visits.
OxfordAges 1–3 - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+ - NCT07423533RecruitingPhase 2
GenSci120 injection for moderate to severe rheumatoid arthritis
This trial tests a new injection called GenSci120 for people with moderate to severe rheumatoid arthritis who haven't improved enough after trying at least one standard arthritis medication. The goal is to see if this treatment can help reduce joint pain and swelling.
Beijing, Beijing MunicipalityAges 18–70 - NCT07423858Recruiting
E-coach for hip and knee arthritis advice
This study tests a digital coach that gives you personalized advice to manage your hip or knee arthritis. It aims to help you get the right guidance at the right time.
UtrechtAges 45 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.