Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT06709365Recruiting
Comparing two surgeries for complex ankle breaks in older adults
This trial tests two ways to fix complicated ankle and lower leg fractures in people over 65. It compares using a nail through the heel versus plates and screws to see which helps you heal and move better.
SohagAges 1–2 - NCT06709690Recruiting
AI-powered PET/MR scanner for children with suspected cancer
This study tests a new, fast, and quiet AI-powered PET/MR scanner to take detailed pictures of children with suspected cancer. It aims to make the imaging experience easier and more comfortable for kids.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07608432RecruitingPhase 3
Testing a New DMD Treatment Given Every 4 Weeks
This study tests whether a new medicine called zeleciment rostudirsen can help ambulatory (walking) males with Duchenne muscular dystrophy (DMD). The medicine is given as an intravenous infusion (through a vein) every 4 weeks and works by helping the body produce a protective muscle protein.
Hillsborough, North CarolinaAges 4–18 - NCT05423587Recruiting
Knee artery procedure for long-lasting knee arthritis pain
This study looks at whether blocking small blood vessels in the knee (genicular artery embolisation) can reduce pain from knee osteoarthritis when other non-surgical treatments haven't helped. It also checks safety and whether people can tolerate the imaging tests needed for the procedure.
ReadingAges 45 years+ - NCT05980793Recruiting
Nerve Treatment for Finger Joint Osteoarthritis
This study tests if a procedure that quiets the nerves around a painful finger joint (PIP joint denervation) can reduce pain and improve hand function for people with osteoarthritis. It offers a possible alternative before considering more invasive surgery.
StockholmAges 18 years+ - NCT07611747RecruitingPhase 4
Ultrasound Screening to Prevent Heart Disease in Rheumatic Patients
This study tests whether using ultrasound to look at arteries in the neck can help prevent heart attacks and strokes in people with inflammatory joint diseases like rheumatoid arthritis or lupus. Researchers will use the results to guide treatment decisions.
Alicante, AlicanteAges 50 years+ - NCT07603674Recruiting
Personalized Primary Care for Muscle and Joint Pain
This trial tests whether tailoring musculoskeletal pain treatment to each patient's unique needs in primary care works better than standard care. You'll work with your regular doctor to find the approach that works best for your specific pain.
StockholmAges 18 years+ - NCT07604714Recruiting
Shoulder Replacement Surgery: Testing a Bone-Removal Technique
This trial compares two surgical approaches for reverse total shoulder replacement—a procedure that replaces a damaged shoulder joint. Researchers are testing whether removing part of a shoulder bone (the coracoid) helps improve your arm's ability to rotate inward after surgery.
AnnecyAges 18 years+ - NCT07611526Recruiting
How Your Body Responds to Special Exercise After Knee Surgery
This study looks at how tired your leg muscles get during a new type of exercise training (called blood flow restriction training) after knee replacement surgery. The goal is to understand how this training affects your recovery and strength.
Bonn, North Rhine-WestphaliaAges 18–85 - NCT07608809Recruiting
Blood Flow Restriction Training vs. Pilates for Shoulder Pain
This study compares two exercise approaches—one using special wraps to limit blood flow during exercise, and standard Pilates—to treat shoulder impingement syndrome (a common condition causing shoulder pain with overhead movements). The goal is to see which method works better at reducing pain and improving shoulder function.
RāshidAges 4 months–1.1 years - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT07611006Recruiting
Shoulder Stability Training With and Without Electrical Stimulation
This study tests whether adding electrical muscle stimulation to shoulder stability exercises helps people with loose, unstable shoulders feel better and move more reliably. You'll do exercises to strengthen the muscles that support your shoulder joint.
TaipeiAges 20–50 - NCT07605650Recruiting
Fascia Release Technique for Forward Head Posture
This study tests whether adding a specialized soft-tissue technique (IASTM) to standard physical therapy helps improve forward head posture better than therapy alone. Forward head posture is when your head juts forward, which can cause neck pain and stiffness.
Giza, Giza GovernorateAges 18–30 - NCT07609758Enrolling by invitation
Study of Hip Socket Fractures in Children
This research study collects information about children who have broken their hip socket (the cup-shaped bone that holds the thighbone). Researchers at University of Utah hospitals want to understand how these fractures heal and what outcomes children have over time.
Salt Lake City, UtahAges 3–18 - NCT07608107Recruiting
Foot Pressure Monitoring for Pelvic Fracture Recovery
This study uses special shoe insoles that measure pressure and weight distribution to help doctors understand how people with pelvic fractures heal and recover their ability to walk. The goal is to improve care and outcomes for patients like you.
Philadelphia, PennsylvaniaAges 65 years+ - NCT07604948Recruiting
Blood Flow Restriction Training for Basketball Recovery
This study tests whether briefly restricting blood flow to the legs (using an arm cuff on the thigh) can help male basketball players recover faster and improve leg strength after games. Researchers want to see if this technique, called ischemic preconditioning, reduces fatigue and speeds healing.
Guangzhou, GuangdongAges 18–25 - NCT07603973Recruiting
Smartphone App to Help Manage Knee Osteoarthritis
This study tests whether a smartphone app that provides information and self-management tools helps people with knee osteoarthritis feel better and manage their condition. You would use the app at home to learn exercises, track symptoms, and get support.
Oslo, OsloAges 50 years+ - NCT07609329Recruiting
Nutritional Support Before Sarcoma Surgery
This study tests whether special nutritional supplements given before surgery for bone or soft tissue sarcoma (a type of cancer) can help your body heal better and recover faster. You'll take oral supplements for at least a week before your planned surgery.
BrnoAges Any age - NCT07609394Recruiting
Duchenne and Becker Muscular Dystrophy Health Records Study
This study collects electronic health records (medical information already in your doctor's computer system) from people with Duchenne or Becker muscular dystrophy, or female carriers of these conditions. Researchers will use this data to better understand the diseases and improve care over time.
Little Rock, ArkansasAges Any age - NCT07603947Recruiting
How Head Posture Affects Balance and Walking
This study looks at how forward head posture (when your head leans forward) impacts your balance and the way you walk. Researchers will measure your head position and analyze your walking patterns to understand this connection.
GizaAges 18–35 - NCT06696287Recruiting
6-minute hand and arm test in fibromyalgia
This study tests a simple 6-minute hand and arm exercise (pegboard and ring test) in people with fibromyalgia. It helps researchers understand how well you can use your hands and arms during daily activities.
KırşehirAges 18–65 - NCT06711575Recruiting
Personalized antibiotics for spinal infections
This trial is studying how to personalize the dose of anti-infection drugs for people with spinal infections. The goal is to find the best treatment for each patient to improve outcomes and reduce side effects.
JinanAges Any age - NCT06711562Recruiting
Personalized Dosing for Bone and Joint Infection
This study aims to customize anti-infection medication doses for people with bone or joint infections. The goal is to make treatment more effective and reduce side effects.
JinanAges Any age - NCT04692714Recruiting
Cemented vs cement-free robotic knee replacement surgery
This trial compares two ways surgeons can attach a knee replacement using robotic-assisted surgery: with cement or without cement. It may help improve how well the new knee lasts and how patients recover after a first-time knee replacement.
LyonAges 50–80
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.