Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06688344Recruiting
Shock wave therapy after ACL surgery
This trial tests if adding focused shock wave therapy to standard rehab can improve recovery after ACL reconstruction using a hamstring graft. It may help reduce pain and speed up healing.
IstanbulAges 18–45 - NCT05111925Recruiting
Testing after-injury and after-recovery readiness for full duty
This study looks at how well service members are able to return to full physical duty after a low-back or leg injury (or to see readiness in those without an injury). It may help improve return-to-duty planning by measuring changes before and after recovery.
Bethesda, MarylandAges 18–44 - NCT07581535Recruiting
Neck and Eye Exercises for Chronic Ankle Instability
This study tests whether specific exercises for your neck and eye movements can help improve balance and stability in ankles that frequently give way or feel unstable. The goal is to see if these exercises reduce symptoms and improve your ankle function.
Izmir, ÇiğliAges 18–45 - NCT07572851Enrolling by invitation
Exercise Program for Preventing Falls in Older Adults
This study looks at how an exercise and wellness program helps older adults stay stronger and reduce their risk of falling. Researchers will track changes in your physical function and balance over time.
A Lama, PontevedraAges 70 years+ - NCT06732700Recruiting
Initial neck exercises for forward head posture and pain
This study tests if initial neck exercises can improve how well you sense your neck's position (proprioception) and reduce pain in people with forward head posture and chronic neck pain.
Islamabad, FederalAges 18–40 - NCT07094178Recruiting
Steroid vs PRP shots for shoulder tendon pain
This trial compares two treatments for shoulder tendinopathy: a corticosteroid shot or a platelet-rich plasma (PRP) injection. It aims to find which one works better to relieve pain and improve function.
TunisAges 18 years+ - NCT06733597Recruiting
Bone density change after knee replacement with or without cement
This study looks at how bone density in the thigh bone changes after knee replacement surgery, comparing two ways of attaching the new joint (with cement or without). It may help people who have normal bone density or early bone thinning but not full osteoporosis.
Madison, WisconsinAges 55 years+ - NCT06120023Recruiting
Long-term follow-up of the Madison knee replacement system
This study follows patients in France who receive a Madison total knee replacement. It watches how well the knee works and how the patient feels over time, to make sure the implant is safe and effective.
Lyon, RhôneAges 18 years+ - NCT07090616Recruiting
Comparing two knee braces after ACL surgery
This study compares two different knee braces used after ACL surgery to see which one helps people recover better. If you are having your first ACL reconstruction, you may be able to join and help find out if one brace works better than the other.
Chicago, IllinoisAges 18 years+ - NCT06386406Recruiting
A pre-made shoe insert for treating heel pain
This study tests a specially designed shoe insole for people with long-term heel pain from plantar fasciitis that hasn't gotten better with other treatments. It aims to see if the insole can help reduce pain and improve walking comfort.
LuganoAges 18–70 - NCT06387459Recruiting
Fabric knee brace for better walking in older adults
This study tests a soft, fabric knee brace designed to help older adults walk better. If you are 65 or older and have muscle weakness, diabetes-related foot numbness, or knee arthritis, this brace may improve your balance and stability.
Seoul, JongnoAges 65 years+ - NCT06736106Recruiting
Spine surgery recovery markers study
This trial looks at how certain markers of bone and muscle health might predict complications after spinal surgery. It could help doctors better understand which patients are at risk and improve recovery.
BolognaAges 18 years+ - NCT06739148Recruiting
Laser therapy for muscle training in healthy adults
This study tests if adding low-level laser therapy to muscle training with electrical stimulation and blood flow restriction can make your workouts more effective. It is for healthy adults aged 20-40.
TainanAges 20–40 - NCT06992271Recruiting
Comparing two exercise styles on muscle recovery
This study tests two different types of arm exercises to see how they affect muscle soreness and damage. If you've lifted weights before but aren't currently doing chest presses every week, this may help you understand how your body recovers after different workouts.
Old Westbury, New YorkAges 18–35 - NCT07560020RecruitingPhase 2
Surlorian for RYR1 muscle weakness: strength and safety study
This trial tests whether a new drug called Surlorian can improve muscle strength in adults with a rare genetic muscle condition (RYR1-related myopathy). You'd receive either the drug or a placebo and be monitored for safety and changes in muscle function.
Marseille, Bouches-du-RhôneAges 18–65 - NCT07543796RecruitingPhase 2
Pain Relief After Hip Replacement Surgery
This study tests whether a new pain medication called TRD205 works well and is safe for people recovering from hip replacement surgery. If it works, it could offer better pain control after your operation.
Guangzhou, GuangdongAges 18–80 - NCT07548567Recruiting
Nerve Block to Reduce Pain During Below-Knee Fracture Surgery
This study tests a nerve-blocking injection (numbing medicine around the femoral artery nerve in your groin area) to help reduce pain and blood pressure changes during below-knee fracture surgery when a tourniquet (pressure cuff) is used. The goal is to see if this approach makes surgery more comfortable and safer.
AthensAges 18 years+ - NCT07147530RecruitingPhase 4
Powered exercise device for walking in hip disease
This study tests a new powered exercise device designed to help people with hip problems walk better. It may be a good option if you have hip osteoarthritis or avascular necrosis and can do some standing and walking with support.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT07564167Recruiting
Dextrose Injection for Tailbone Pain Relief
This study tests whether injecting dextrose (a sugar solution) under ultrasound guidance can relieve chronic tailbone pain that hasn't improved with standard treatments like physical therapy or medication. The injection is designed to stimulate healing in the painful area.
IstanbulAges 18–75 - NCT07537036Recruiting
Pain Relief Methods for Hip Replacement Surgery
This trial compares two nerve-blocking techniques to reduce pain after hip replacement surgery. Both methods use numbing medication around specific areas near your hip to help you feel more comfortable after the operation.
Tanta, El-GharbiaAges 18 years+ - NCT05733377Recruiting
Non-invasive scans to study back curve during pregnancy
This trial uses a non-invasive imaging scan to measure a common back curvature called lordosis during pregnancy. Researchers will look at how these measurements relate to birth outcomes in low-risk pregnancies.
Alcalá de Henares, MadridAges 20–40 - NCT07588061Recruiting
Neck Pain Treatment: Mobilization and Posture Exercises
This study tests whether combining two types of physical therapy—manual joint mobilization and specific posture-strengthening exercises—can reduce neck and upper back pain and improve how you hold your body. You may qualify if you have persistent neck pain linked to poor posture.
Peshawar, KPKAges 18–45 - NCT06078085Recruiting
Abdominal muscle separation study and rehab program
This trial tests a rehabilitation program for people with abdominal muscle separation (diastasis recti) that is larger than 3 cm. It may help if you are at least one year past childbirth or weight loss and have a BMI under 30.
Mora, Dalarna CountyAges 18–65 - NCT06637579Recruiting
Exercise Program for Walking in Children with Cerebral Palsy
This trial tests a special exercise program (Universal Exercise Unit) plus task-focused training for children with spastic cerebral palsy. It aims to help with walking, balance, and daily activities.
Sialkot, Punjab ProvinceAges 5–15
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.