Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07616583Recruiting
Vertebral Fracture Treatment with Precise Cement Injection
This study tests a new method for treating recent spine fractures caused by weak bones (osteoporosis). A surgeon injects special cement into the broken vertebra to stabilize it and reduce pain. You'll be one of the first to receive this standardized technique.
Beijing, Beijing MunicipalityAges 50–80 - NCT07615361Enrolling by invitation
Tooth Graft and Laser Therapy for Dental Implants
This study tests whether material from extracted teeth, combined with low-level laser treatment, can help bone heal better before dental implants are placed. The goal is to improve implant success and reduce bone loss after tooth removal.
Istanbul, UskudarAges 18–65 - NCT07614672Enrolling by invitation
Instrument-Assisted vs. Manual Massage for Heel Pain
This study compares two hands-on treatment techniques for plantar fasciitis—a common cause of heel pain. Researchers want to see which approach works better to reduce pain and improve how you walk.
Islamabad, FederalAges 19–64 - NCT07613333Recruiting
Exercise Program for New Mothers
This study tests an exercise program designed for women who have given birth within the past 2 years. Researchers want to learn how exercise affects energy levels and overall health after pregnancy.
Waukesha, WisconsinAges 18 years+ - NCT07616401Recruiting
Bone-Strengthening Drugs and Biomarkers in Postmenopausal Osteoporosis
This study tests two injectable medications (romosozumab and abaloparatide) that help strengthen bones in women after menopause. Researchers will also look at blood markers to understand why some women respond better to treatment than others.
Miano, LombardyAges 50 years+ - NCT07614945Recruiting
Reflexology for Pain and Sleep in Fibromyalgia
This study tests whether reflexology—a massage technique applied to specific points on the feet and hands—can help reduce pain and improve sleep in women with fibromyalgia. Fibromyalgia causes widespread muscle pain and sleep problems, and this trial explores whether reflexology might offer relief.
Al Mansurah, Dakahlia GovernorateAges 18–65 - NCT07615322Recruiting
Smartphone Use, Posture, and Breathing in College Students
This study explores how smartphone addiction affects posture and breathing in young adults. Researchers will measure your posture, breathing patterns, and smartphone habits to understand if heavy phone use changes how you stand and breathe.
Maltepe, IstanbulAges 18–35 - NCT07618403Recruiting
Physical Therapy for Knee Arthritis
This study tests whether a structured physical therapy program helps knee arthritis pain and function. Researchers will also look at how your expectations about treatment affect your results.
Ankara, YenimahalleAges 50 years+ - NCT07615829Recruiting
Dance Exercise and Health Benefits in Women
This study examines how regular dance exercise affects overall health and wellbeing in women. Researchers want to understand if dancing can improve physical fitness, mood, and other health markers.
Trikala, KariesAges 35–70 - NCT07619846Recruiting
Chin Bone Rings for Dental Implants in Back Teeth
This surgery uses a special bone ring taken from your chin to build up bone in your back upper jaw, so dental implants can be placed in one procedure instead of two. This may reduce surgery time and help your implants succeed better.
Damascus, GovernorateAges 18–70 - NCT07615491Recruiting
Safety and effectiveness study of spinal implants and bone materials
This study tracks how well spinal implants (Titania systems) and bone-filling materials (BONEGRAFT) work after surgery and whether patients experience any problems. Researchers will follow patients after cervical or lower spine surgery to confirm these devices are safe and effective in real-world use.
IzmirAges 18 years+ - NCT06706037Recruiting
Reformer exercise for chronic muscle and joint pain
This study tests if Reformer Pilates exercises can reduce pain for people with long-term muscle or joint pain. It may help you feel better and move more easily.
Ankara, Select StateAges 30–50 - NCT06706531Recruiting
Dry needling plus physical therapy for plantar fasciitis
This study tests whether adding dry needling (a technique using thin needles to release muscle knots) to standard physical therapy works better than physical therapy alone for treating long-term heel pain known as plantar fasciitis.
Rawalpindi, Punjab ProvinceAges 18–35 - NCT06706492Recruiting
Muscle oxygen and frailty in kidney transplant patients
This study looks at how well muscles use oxygen and how frailty affects kidney transplant recipients, especially those with weak breathing muscles. It may help understand why some patients feel more tired or weak after transplant.
AnkaraAges 18–65 - NCT04191395Recruiting
Study of treatments for long-term inflammatory diseases
This study looks at how chronic inflammatory illnesses progress over time and how treatments affect symptoms and disease markers. You may be invited if you’re receiving care for certain bowel, joint, or skin inflammatory conditions at the hospital.
BesançonAges 18 years+ - NCT06707870Recruiting
Neck exercises for chronic pain relief
This trial compares two different treatments for long-lasting neck pain: a special exercise that helps with neck posture (cervical retraction) and a gentle manual therapy technique (facet oscillatory mobilization). It aims to find which method is better at reducing pain and improving neck movement.
Peshawar, KPKAges 35–50 - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06708377Recruiting
Dry needling and massage for jaw joint pain
This trial tests whether dry needling combined with myofascial massage therapy can help relieve pain and improve jaw movement in people with temporomandibular joint (TMJ) dysfunction. It compares this treatment to standard care to see which works better.
Islamabad, FederalAges 25–45 - NCT06707363Recruiting
Psychological factors and pain after orthopedic surgery
This study looks at how your thoughts and feelings affect your pain after orthopedic surgery. Researchers want to understand these factors to improve care for future patients.
Krakow, MalopolskaAges 18–65 - NCT03976245RecruitingPhase 4
Tested new advanced treatment options for rheumatoid arthritis
This trial studies advanced medicines for rheumatoid arthritis (RA) in people whose RA is still active despite several standard treatments. It may help by testing whether a different advanced option can better control symptoms and joint inflammation.
London, OntarioAges 18 years+ - NCT01706692Recruiting
Study registry for targeted treatments in psoriasis patients
This trial is a registry that collects information from adults with plaque psoriasis or psoriatic arthritis who are starting a new biologic or other systemic treatment. It helps researchers understand how these treatments are used in real life and what outcomes they may have.
AarauAges 18 years+ - NCT04081896Recruiting
Rehab program for adults with spine pain
This trial studies whether a prescribed physical therapy (rehab) program helps people with spine pain. It may help by improving pain and function when a clinician has already recommended rehabilitation.
San Diego, CaliforniaAges 18–89 - NCT06612853Recruiting
Sleep Quality Scale Validation for Spine Patients
This study tests a single question about sleep quality to see if it works well for people with spine problems. You will fill out a simple questionnaire and may help improve how sleep is measured in future spine care.
Zurich, Canton of ZurichAges 14 years+ - NCT06683222Recruiting
How muscle and bone talk to each other in healthy women
This study looks at how signals from muscles affect bone health in women of different ages. It aims to understand why bone density changes over time.
MontpellierAges 20–89
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.