Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT05757739Recruiting
Open debridement versus Tenex for tennis elbow
This trial compares two ways to treat chronic tennis elbow (lateral epicondylitis). It’s meant to see which option works better for long-lasting pain that affects daily activities.
Burlington, New JerseyAges 18–70 - NCT06746168Recruiting
Better pain control after knee replacement surgery
This study tests a new way to manage pain after total knee replacement. It aims to see if a specific local pain block can reduce the need for strong opioids and improve recovery.
Hasselt, LimburgAges 18–85 - NCT07470021Recruiting
Numbing injection for pain relief after ankle surgery
This study tests whether a numbing injection around the ankle nerves before surgery can reduce pain and help you recover faster after ankle arthroscopy. It is for people having this keyhole surgery and staying in the hospital for a short time.
Hangzhou, ZhejiangAges 18–65 - NCT06989229Recruiting
Nutritional care before and after joint replacement surgery
This trial tests if special nutritional support before and after hip or knee replacement helps you recover faster. It is for people having planned (not emergency) surgery.
Brno, CzechiaAges 18 years+ - NCT06448520Recruiting
Muscle power sprint test in children
This study is measuring how fast and powerful kids' legs are during a short sprint test. Researchers want to collect normal values from healthy children so doctors can compare results in the future.
Rotterdam, South HollandAges 5–12 - NCT06737809Recruiting
Silver-coated hip revision for infection
This trial tests a new silver-coated hip implant for people who need a revision due to a chronic infection around the joint. It may help control the infection while replacing the implant.
BerlinAges 18 years+ - NCT07526831Recruiting
Pain Relief Methods for Knee Surgery: Two Nerve Block Approaches
This study compares two ways of numbing nerves around the knee during surgery to see which method reduces pain better after the operation. Both methods use safe, well-established pain-relief techniques.
Kayseri, TalasAges 18 years+ - NCT07705698Recruiting
Nordic exercise for young female pole vaulters
This study compares two types of Nordic hamstring exercises—one with blood flow restriction and one without—to see which better helps elite young female pole vaulters strengthen their hamstrings and reduce injury risk.
AdanaAges 12–18 - NCT06762392Recruiting
Blood flow restriction for ACL rehab: a pilot study
This study tests whether using a special band that slightly restricts blood flow (blood flow restriction) during rehabilitation can help people recover better after ACL knee surgery. It's a small early study to see if this method is safe and effective.
Valencia, ValenciaAges 18 years+ - NCT07703007Enrolling by invitation
Clear aligners for growing kids with mild underbite
This study tests whether clear aligners can fix a mild underbite in growing children aged 8 to 11. It compares how well the aligners move teeth and jaws compared to other treatments.
Al Mansurah, Dakahlia GovernorateAges 8–11 - NCT06729983Recruiting
Tendon lengthening during reverse shoulder replacement
This study tests whether slightly lengthening a tendon during reverse shoulder replacement improves outcomes. It's for adults getting their first reverse replacement at Loyola sites.
Maywood, IllinoisAges 18 years+ - NCT06967220Enrolling by invitation
Inflammation's effect on muscle in hospitalized patients
This study tests whether inflammation affects muscle loss in older hospitalized patients who are malnourished. It could help find ways to protect muscle strength during a hospital stay.
CopenhagenAges 65 years+ - NCT06010433Recruiting
CERAMENT G treatment tracking study
This study tracks how well the CERAMENT G device works for people getting it as part of their treatment. It helps doctors gather real-world safety and effectiveness information.
San Diego, CaliforniaAges 18 years+ - NCT07026890Recruiting
Virtual reality for elderly with psychomotor disadaptation
This trial tests if using virtual reality can help older adults who have trouble moving and adapting to their surroundings (psychomotor disadaptation syndrome). It aims to improve their care while in a hospital geriatric unit.
DijonAges 65 years+ - NCT07025252Enrolling by invitation
VersaWrap patch for Achilles tendon repair
This trial tests a special wrap (VersaWrap) used during surgery to repair a torn or damaged Achilles tendon. It may help the tendon heal better and could be an option for people who need this type of surgery.
Sacramento, CaliforniaAges 18–90 - NCT07010146RecruitingPhase 2
Estrogen's Effect on Bone Health in FHA
This study tests how estrogen treatment affects bone strength in young women with Functional Hypothalamic Amenorrhea (FHA), a condition where periods stop due to stress, low weight, or over-exercise. Participants who have had very few periods will receive estrogen to see if it improves bone density.
Charlottesville, VirginiaAges 14–30 - NCT07636343Recruiting
Eccentric Training for Heart Failure Recovery
This trial tests a special type of strength training (eccentric exercise, where muscles lengthen under load) for people with heart failure who have reduced pumping ability. The goal is to improve your exercise capacity and heart function safely.
EdegemAges Any age - NCT04720365Recruiting
Home video game rehab to help Parkinson’s walking and balance
This trial tests whether a serious (therapeutic) home video-game program can improve walking and balance problems for people with Parkinson’s disease who still have trouble even with levodopa. It also looks at whether the approach is worth it in real-world care (cost and benefits).
BordeauxAges 18 years+ - NCT07695168Recruiting
Digital course and rehab for knee osteoarthritis
This study tests whether a digital program with special sensors and a digital twin can help reduce knee pain and improve mobility in older adults with knee osteoarthritis. It also includes healthy adults for comparison.
TaipeiAges 20–80 - NCT06715085RecruitingPhase 4
PRGF injections for chronic low back pain
This trial tests whether injections of a blood-based treatment called PRGF can help people with long-term low back pain caused by worn discs. It is for those who haven't gotten relief from standard treatments like medication.
Vitoria-Gasteiz, AlavaAges 18 years+ - NCT06711562Recruiting
Personalized Dosing for Bone and Joint Infection
This study aims to customize anti-infection medication doses for people with bone or joint infections. The goal is to make treatment more effective and reduce side effects.
JinanAges Any age - NCT07504653Recruiting
Game rehab for shoulder blade issues in Frisbee players
This trial tests a fun, game-based rehab program for Ultimate Frisbee players with a shoulder blade condition called scapular dyskinesia. It focuses on improving your shoulder movement and strength through interactive exercises.
Seremban, Negeri SembilanAges 18–40 - NCT07689747Recruiting
Brain training and ankle tests for athletes with weak ankles
This study tests if adding a special computer-based brain training activity to regular ankle function tests can help teenage and young adult athletes who have ongoing ankle problems. If you are a licensed football, basketball, or volleyball player aged 16–25 with chronic ankle instability for at least a year, you may be eligible.
Istanbul, SarıyerAges 16–25 - NCT06483256Recruiting
Outcomes after surgery for biceps tendon injury
This study looks at how well patients do after surgery for a biceps tendon injury, using a specific surgical technique. It may help you understand what results to expect if you have had this type of surgery.
BolognaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.