Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT06713902Recruiting
Extracellular vesicles in fibrin gel for cartilage repair
This trial studies whether adding special healing particles (extracellular vesicles) to a natural gel can help repair cartilage in people with knee or hip osteoarthritis. It looks at patients already scheduled for surgery or regenerative treatments like PRP.
Milan, MIAges 18 years+ - NCT05812885Recruiting
TENS for long-lasting low back pain
This study tests whether transcutaneous electrical nerve stimulation (TENS), a non-drug pain treatment using small electrode pads on the skin, can help people with low back pain. You may be eligible if your back pain has lasted at least 3 months and your pain is at least moderate.
West Hartford, ConnecticutAges 18–60 - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT06714747Recruiting
Soft tissue prediction for jaw surgery
This trial tests a new way to predict how facial soft tissues will change after jaw surgery using advanced imaging. It may help people needing orthognathic surgery to understand the likely aesthetic outcome.
Bologna, Emilia-RomagnaAges 18 years+ - NCT07596693RecruitingPhase 1
KXV01 injection for advanced solid tumors
This early-stage trial tests KXV01, a personalized cancer treatment made from your own immune cells, for advanced solid tumors that have not responded to standard treatment. The goal is to see if it can help control your cancer and learn about its safety.
ShanghaiAges 18–70 - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07599865RecruitingPhase 2
Bubble study for knee infection after joint replacement
This trial tests if a contrast agent used in ultrasound can help surgeons see pockets of infection around knee implants during revision surgery. It may help doctors do a better job cleaning out the infection.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07595718Recruiting
Using health data and AI to predict major diseases
This study uses your health information and artificial intelligence to help predict the onset of major diseases. By joining, you could help improve early detection and prevention for conditions like diabetes, heart disease, and cancer.
Seoul, Seoul Special CityAges 30–65 - NCT07602933Recruiting
Light Therapy for Muscle Fatigue from Electrical Stimulation
This study tests whether light therapy can reduce muscle fatigue and damage caused by electrical muscle stimulation. Researchers want to see if this non-invasive light treatment helps muscles recover faster.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07596953Recruiting
TECAR therapy for long-term neck pain and stiffness
This study tests whether TECAR therapy—a heat-based treatment that uses electrical energy—can reduce neck pain and improve movement in people with chronic neck stiffness. TECAR stands for capacitive and resistive energy transfer, a non-invasive technique that may help relieve pain and restore mobility.
Jeddah, Al ZahraaAges 20–40 - NCT07601906Recruiting
Blood Flow Exercise Therapy After Knee Replacement Surgery
This study tests whether special exercises that temporarily reduce blood flow to your leg can help you recover better after knee replacement surgery. It focuses on reducing pain and improving your ability to bend and straighten your knee.
Lahore, Punjab ProvinceAges 50–65 - NCT07599059Enrolling by invitation
AI-assisted ultrasound therapy for frozen shoulder
This trial tests a new AI-assisted ultrasound therapy for frozen shoulder (adhesive capsulitis). It aims to see if this non-invasive treatment can help improve shoulder stiffness and movement without the need for surgery or injections.
TaipeiAges 18 years+ - NCT07598474Recruiting
Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Faisalābad, Punjab ProvinceAges 40–60 - NCT07600632Recruiting
Hip Replacement Surgery Outcomes Using Short Stem
This study reviews results from hip replacement surgery using a special short implant inserted through a small front-of-hip incision. Researchers want to understand how well this approach works and how long the implant lasts.
BolognaAges 18 years+ - NCT07600229Recruiting
Barefoot Walking vs. Standard Care for Heel Pain
This study compares barefoot walking to standard conservative care (like stretching and supportive shoes) for plantar fasciitis—a common cause of heel pain. Researchers want to see if walking barefoot helps reduce pain and improve function in people with persistent heel discomfort.
Carlow, Carlow CountyAges 18–70 - NCT07597343Recruiting
Helping You Stick With Hip Pain Exercise Treatment
This study tests new ways to help people with lateral hip pain (pain on the outer side of the hip) stay motivated and consistent with their exercise program. The goal is to understand what helps patients do their exercises regularly so they can feel better.
Leicester, LeictershaireAges 18 years+ - NCT07597850RecruitingPhase 2
TCM formula versus HMB supplement for muscle strength in older adults
This study compares a traditional Chinese medicine formula with HMB (a muscle-building supplement) to see which helps preserve muscle strength and bone health in adults aged 65 and older who are starting to show signs of frailty. Both treatments aim to help you stay stronger and more active as you age.
TaipeiAges 65 years+ - NCT07598539Recruiting
Knee replacement recovery care at UPMC
This study compares different rehabilitation plans after knee replacement surgery to find the best way to help you recover. If you're having knee replacement at a UPMC hospital and plan to use UPMC for your rehab, this trial may be for you.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07600437Recruiting
Muscle and Joint Problems in Musicians Study
This research study examines how common muscle, joint, and bone problems are among people who play musical instruments. Researchers will ask you questions and may do physical assessments to understand which musicians are most affected and why.
Multiple LocationsAges 18 years+ - NCT07597356Recruiting
AI Video Analysis of How Children Move and Develop
This study uses artificial intelligence to analyze videos of children performing simple movements and activities. Researchers want to see if this new video-based method can accurately assess how well children's bodies are developing and moving.
Istanbul, BeykozAges 5–10 - NCT07600359Recruiting
Physical therapy techniques for sacroiliac joint pain
This study compares two hands-on physical therapy techniques to reduce lower back pain, improve walking, and restore function in people with sacroiliac joint dysfunction (a condition affecting the joint connecting your spine to your pelvis). You'll receive treatment and be assessed to see which technique works better.
Islamabad, Punjab ProvinceAges 25–45 - NCT07597538Recruiting
How Hip Replacement Changes Knee Position and Function
This study examines whether getting a hip replacement changes how your knee aligns and functions. Researchers will compare knee imaging before and after your surgery to understand this connection.
Asyut, Asyut GovernorateAges Any age - NCT07598487Enrolling by invitation
Physical Therapy Techniques for Stroke Recovery and Balance
This study compares two types of physical therapy to help people regain trunk control and balance after a stroke. Participants will receive either PNF (a hands-on technique using rhythmic movements) or NDT (another hands-on technique focusing on movement patterns) to improve stability.
Faisalabad, Punjab ProvinceAges 40–65 - NCT04001842Recruiting
Tested new jaw bone repair to support future dental work
This trial is studying a method to rebuild part of the lower jaw using a blood-supply bone replacement, so you can later get dental rehabilitation. It’s for adults who need a sizable, tumor-free jaw bone reconstruction and who can safely undergo surgery.
AlexandriaAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.