Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT06946368Recruiting
Exparel for pain after knee replacement
This study tests if a long-lasting numbing medicine called Exparel, given by the surgeon during knee replacement, helps control pain after surgery. It is for people having their first total knee replacement on one knee due to arthritis.
Cleveland, OhioAges Any age - NCT06600308Recruiting
Walking study for people with facioscapulohumeral muscular dystrophy
This study looks at how walking changes over time in people with facioscapulohumeral muscular dystrophy (FSHD). It aims to understand walking patterns to help improve future care.
DijonAges 18 years+ - NCT06600685Enrolling by invitation
Music therapy for long-term pain
This study tests whether a special type of music therapy (called FMT) can help reduce long-term pain in muscles and bones. If you have had pain for at least 3 months and can speak Swedish or English, this may be an option for you.
Eskilstuna, EskilstunaAges 18 years+ - NCT05895968Recruiting
Barbed Suture for Obese Patients Having Neck Surgery
This trial tests a special type of stitch (called barb suture) used during back-of-neck surgery. It is for people who are obese and need surgery for cervical spinal problems, to see if it helps recovery.
Xi'an, Shannxi ProvinceAges 28–85 - NCT07735429Recruiting
Comparing arm function in wheelchair arm wrestling and archery athletes
This study compares arm speed, strength, and coordination between wheelchair athletes in two sports: arm wrestling and archery. It helps researchers understand how different training affects arm function.
IstanbulAges 18–45 - NCT06596031Enrolling by invitation
Health coaching for people waiting for hip or knee replacement
This study tests whether health coaching can help people who are waiting for hip or knee replacement surgery. It aims to improve your health and wellbeing while you wait for your operation.
SheffieldAges 18 years+ - NCT06947655Recruiting
Tourniquet types for knee replacement surgery
This study compares different types of tourniquets (tight cuffs) used during knee replacement surgery to see how they affect blood loss and how satisfied surgeons are with them.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07405060Recruiting
How age and muscle fatigue affect balance and control
This study looks at how getting older and muscle tiredness change your ability to keep your balance and control your movements. It may help explain why some people are more likely to fall.
TaoyuanAges 20–85 - NCT07453004RecruitingPhase 2
Study of plonmarlimab for frequent gout attacks
This trial tests a new investigational drug called plonmarlimab for people with frequent, painful gout flares who cannot take standard treatments. The goal is to see if it can reduce pain and inflammation from the flare.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06590402RecruitingPhase 4
Nerve blocks for pain relief after kids' knee surgery
This study compares two types of nerve blocks to manage pain after knee surgery in children and teens. It is for patients aged 8 to 18 having a first-time ACL or MPFL reconstruction.
New York, New YorkAges 8–18 - NCT06590701Recruiting
Wrist ligament surgery rehab: early motion study
This study compares two different ways of moving the wrist after surgery to repair a specific wrist ligament (the scapholunate ligament). The goal is to see which type of early motion leads to better recovery.
Zurich, Canton of ZurichAges 18 years+ - NCT06589557Enrolling by invitation
VR therapy for neck disc disease
This study tests a new VR therapy to help people with neck pain caused by cervical disc disease. It aims to improve movement and reduce pain without surgery.
Rzeszów, Al. Rejtana 16CAges 18–65 - NCT07732803Recruiting
Robotic surgery results for bone injuries
This study looks at how well robots can help in surgery for broken bones and other orthopedic injuries. If you are an adult with a fracture and need surgery, you may be able to join.
Hong KongAges 18 years+ - NCT07295184Recruiting
Rebound pain and confusion after hip surgery
This study looks at a way to reduce confusion after hip surgery. If you are having planned hip surgery and get a nerve block for pain, researchers will check if rebound pain affects your recovery in the hospital.
Konya, KaratayAges 18–80 - NCT06568198RecruitingPhase 2
Brain stimulation study for chronic low back pain
This trial tests whether a noninvasive brain stimulation technique called tACS can help reduce chronic low back pain. Participants will have brain scans and receive the treatment over several sessions.
Charlestown, MassachusettsAges 18–60 - NCT07396077Recruiting
Pre-op health boost for elderly spine surgery patients
This trial tests if a 6-week prehabilitation program (exercise and nutrition) before spine surgery helps elderly patients recover better. It is for people 75 or older with long-term lower back problems who need spinal fusion surgery.
Beijing, Beijing MunicipalityAges 75 years+ - NCT06562062Recruiting
New surgery for flexible flat foot
This study tests a modified surgical technique to fix a painful, flexible flat foot in adults who haven't improved with nonsurgical care. It may help by repairing a key ligament on the outside of the knee to support the arch.
Asyut, AssiuuAges 16–65 - NCT06560190Recruiting
Physical therapy after childbirth for active-duty moms
This study tests whether hands-on physical therapy (called orthopaedic manual therapy) can help active-duty moms recover from childbirth. If you join, you'll receive specialized treatment to ease pain and improve movement during the early postpartum months.
San Antonio, TexasAges 18–44 - NCT06556771Recruiting
Comparing two mobilization techniques for neck pain relief
This study compares two hands-on therapy methods (Gongs and Kaltenborn mobilization) to see which one works better for reducing mechanical neck pain. If you have neck pain that gets worse with movement or sitting still, this trial may help find a more effective treatment for you.
Attock City, Punjab ProvinceAges 18–65 - NCT06552533Recruiting
Strengthening with jumps for ankle stability
This trial compares two types of leg exercises to see which better helps athletes with chronic ankle instability that did not heal with usual rehab. You would do resistance training alone or combined with jumping exercises.
Lahore, Punjab ProvinceAges 18–35 - NCT05640336Enrolling by invitation
Antibiotics for early knee or hip joint infections after surgery
This study compares two antibiotic plans for acute (early) infections around an artificial knee or hip, using a procedure to clean the joint and try to keep the implant. It may help find the best approach to control infection and then prevent it from coming back with longer-term antibiotic treatment.
Jacksonville, FloridaAges 18 years+ - NCT06542471Enrolling by invitation
Plates vs rods for pediatric forearm fractures
This trial compares two surgical approaches for kids with broken both forearm bones: using metal plates or a flexible rod inside the bone. It aims to see which method leads to better healing, so you can get back to playing sooner.
CairoAges 9 years+ - NCT07664202Recruiting
Fluoroscopic Endobutton Procedure for Collarbone Injuries
This study is testing a surgical technique called fluoroscopic endobutton repair for outer collarbone fractures or severe acromioclavicular joint dislocations. It aims to see if using a special X-ray during surgery helps improve how the bone heals or the joint is stabilized.
ParisAges 18–65 - NCT06543888Recruiting
Exoskeleton training for walking and daily tasks in older adults
This study tests whether a passive lower-limb exoskeleton can help older adults walk better and do daily activities more easily. You will wear the device during training sessions to see if it improves your movement and independence.
Taoyuan, GuishanAges 60 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.