Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT07419633Recruiting
Study on supplements to improve strength and thinking in older adults
This trial tests if two supplements, HMB and 2-HOBA, taken alone or together, can help improve muscle strength and mental function in healthy adults over 65. The goal is to see if these supplements can improve overall quality of life.
Montreal, QuebecAges 65 years+ - NCT07416656Recruiting
Checking blood sugar test accuracy for arthritis patients on sulfasalazine
This study checks if the medicine sulfasalazine affects a blood sugar test (HbA1c) in people with inflammatory arthritis. If you have arthritis, take sulfasalazine, and have higher blood sugar or diabetes, this trial may help understand your glucose levels.
Silkeborg, Central JutlandAges 18 years+ - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+ - NCT07419269Recruiting
Comparing donor vs. patient bone grafts for jawbone repair
This trial tests whether donated (allogenic) bone blocks work as well as your own bone to rebuild the jaw so dental implants can be placed. It's for people missing 1-4 teeth where the bone ridge is too thin.
Graz, StyriaAges 18 years+ - NCT07424742Recruiting
Toothless upper jaw implant study without bone grafts
This trial tests a way to place dental implants in the upper jaw where bone is thin (4-6 mm height) without needing a bone graft. It uses special self-tapping implants to lift the sinus floor gently through the implant site.
Sanaa, Sanaa GovernorateAges 18–80 - NCT07418632Recruiting
Motion training for neck pain using smart classification
This study tests a special motion-training program for people with neck pain. It uses a computer to classify and guide your movements, which may help reduce pain better than usual care.
LjubljanaAges 18–65 - NCT07423858Recruiting
E-coach for hip and knee arthritis advice
This study tests a digital coach that gives you personalized advice to manage your hip or knee arthritis. It aims to help you get the right guidance at the right time.
UtrechtAges 45 years+ - NCT07416916RecruitingPhase 4
Comparing two ways to inject steroids for frozen shoulder
This trial compares two injection methods for frozen shoulder: one directly into the shoulder joint and one into the buttock muscle. It aims to see which works better for pain and movement.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07424352Recruiting
Rotational exercise for knee osteoarthritis
This study tests a special rotational exercise device to see if it can improve knee function and reduce pain in people with knee osteoarthritis. It involves supervised sessions at the university and may help you move better without surgery.
Aurora, ColoradoAges 40–70 - NCT07419451Recruiting
Bone health and health knowledge study for older adults
This study looks at how much older adults know about osteoporosis and their overall health understanding. It aims to help improve education and awareness about bone health in aging.
Balıkesir, BandırmaAges 65 years+ - NCT07424703Recruiting
Bright Light Therapy for Teen Scoliosis
This study tests whether using a special bright light device at certain times of day can help improve spine curvature in teenagers with scoliosis. It is for adolescents who are night owls and have mild to moderate scoliosis.
Zhejiang, ZhejiangAges 10–15 - NCT07425613Recruiting
Neck movement before and after disc surgery
This study looks at how neck movement control changes after a common surgery (ACDF) for a damaged disc. It compares people having surgery with those who have neck pain but are not having surgery, to understand how the neck moves before and after treatment.
LjubljanaAges 18–65 - NCT07419399Recruiting
Radiofrequency treatment for belly muscle separation after childbirth
This study tests if a non-invasive radiofrequency treatment can help close the gap in belly muscles (diastasis recti) in women who are 6 months to 1 year postpartum. It aims to improve muscle function and appearance without surgery.
Valencia, ValenciaAges 20–45 - NCT07416357Recruiting
Knee OA ultrasound study for Turkish adults
This study tests whether a standard set of ultrasound measures for knee osteoarthritis is reliable and valid for Turkish patients. It may help doctors better assess knee OA using ultrasound.
Izmir, İzmirAges 45 years+ - NCT07418684Recruiting
Comparing two versus four 3D miniplates in jaw surgery
This trial compares using two custom titanium miniplates versus four to fix the upper jaw after surgery to correct jaw and teeth misalignment. The goal is to see which approach provides better stability and healing.
CairoAges 18–40 - NCT07422714Recruiting
Wearable device system for frozen shoulder rehab
This trial tests a wearable device that guides you through exercises to help recover from frozen shoulder. It is designed for people in the 'frozen' phase of the condition.
BeijingAges 40–60 - NCT06769386Recruiting
Muscle Oxygen in Rheumatoid Arthritis
This study looks at how muscles use oxygen in people with rheumatoid arthritis. You will do some exercise tests to measure your muscle oxygen levels, which may help doctors understand how the disease affects your muscles.
Kırşehir, MerkezAges 18–65 - NCT06804564Recruiting
Cold vs warm water for muscle pain recovery
This trial compares cold water and warm water immersion to see which helps recover from muscle soreness after exercise. If you are a healthy young man with moderate muscle pain from working out, this study may help you recover faster.
Biała Podlaska, Lublin VoivodeshipAges 18–25 - NCT06820073Recruiting
Stretching study for office workers with neck or back pain
This study tests if a gentle stretching method using a special hammock can help reduce neck and back discomfort for people who sit at work. It's looking for volunteers who have some aches but no serious diagnoses.
Zaragoza, ZaragozaAges 18–65 - NCT03915106Recruiting
Quality of life in teens with scoliosis needing brace or surgery
This study looks at how much day-to-day quality of life changes for people with adolescent idiopathic scoliosis who either need a brace or need surgery. It uses a short questionnaire to understand how treatment affects comfort, activity, and overall well-being.
ShatinAges Any age - NCT06507072Recruiting
Adaptive rock climbing for kids with arm differences
This study tests whether adaptive rock climbing can help children with arm or hand differences improve their physical function and confidence. It aims to find fun and effective ways to support your child's development.
Los Angeles, CaliforniaAges 6–16 - NCT06776887Recruiting
Virtual reality exercises for burn recovery on legs
This trial tests whether virtual reality exercises can help people with leg burns improve balance and reduce depression and anxiety. It is for people who had a large thermal burn on their lower body at least 3 months ago.
GizaAges 35–55 - NCT07409103RecruitingPhase 2
Testing ELV001 for active rheumatoid arthritis
This study tests a new medication, ELV001, for people with active rheumatoid arthritis who haven't improved enough with methotrexate and a TNF inhibitor. The goal is to see if different doses of ELV001 are safe and can help reduce joint pain and swelling.
Gilbert, ArizonaAges 18–75 - NCT07412704RecruitingPhase 1/Phase 2
Study of BMS-986528 for hard-to-treat rheumatoid arthritis
This trial tests a new drug called BMS-986528 for people with rheumatoid arthritis that is difficult to treat. It aims to see if the drug can help when other treatments haven't worked well.
La Jolla, CaliforniaAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.