Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT07446400RecruitingPhase 1
Drug interaction study for repinatrabit
This trial tests how repinatrabit interacts with common medications like birth control, metformin, and others. It helps doctors understand safe dosing and potential side effects.
Melbourne, VictoriaAges 18–55 - NCT07166536Recruiting
Study on mental imagery and symptom worsening after concussion
This trial tests whether mental imagery tasks can trigger or worsen headaches and dizziness in people with long-lasting symptoms after a mild traumatic brain injury or concussion. If you still have headaches or dizziness more than 3 months after your injury, this study may help understand how your brain reacts to mental exercises.
Tel AvivAges 18–74 - NCT07613710RecruitingPhase 1
Safety study of Lu AH69593 for healthy adults or narcolepsy
This study tests whether a new medication called Lu AH69593 is safe and well-tolerated in healthy adults and people with narcolepsy type 1. Researchers want to understand how the drug affects the body and whether it could help treat excessive daytime sleepiness.
HelsinkiAges 18–64 - NCT07120880RecruitingPhase 3
Light therapy timing for depression with insomnia
This trial tests whether giving light therapy at a specific time of day can improve both depression and sleep problems. It is for adults with major depression and insomnia who are not currently on antidepressants.
ParisAges 18–65 - NCT07502599Recruiting
Fainting detection and early warning in syncope study
This study tests a new way to detect and warn about fainting in people with certain types of syncope (temporary loss of consciousness). It may help those who have already had a specific fainting evaluation called an ARS assessment.
Rochester, MinnesotaAges 18 years+ - NCT02300766Recruiting
Study of cerebellar mutism in children with brain tumors
This study looks at how children with certain brain tumors develop “cerebellar mutism” after surgery or an open biopsy. The goal is to better understand the syndrome and what might help support recovery.
ViennaAges Up to 18 years - NCT07264283Enrolling by invitationPhase 2
Testing LM11A-31 for progressive supranuclear palsy
This trial tests a drug called LM11A-31 to see if it can help people with progressive supranuclear palsy (PSP), a rare brain condition. You may join if you have had symptoms for 5 years or less, can walk with minimal help, and have good thinking abilities.
San Francisco, CaliforniaAges 41–86 - NCT06908226Enrolling by invitationPhase 3
LP352 for children and adults with DEE
This trial tests a medication called LP352 for children and adults with certain types of epilepsy (Dravet syndrome, Lennox-Gastaut syndrome, or other developmental and epileptic encephalopathies). It's for people who already completed a previous study of LP352 and may benefit from continued treatment.
Little Rock, ArkansasAges 2–66 - NCT07348666Recruiting
Smartphone safety planning for teens at risk
This trial tests a smartphone-based safety planning tool that gives you support right when you need it. It's designed for teens and young adults who are at risk for suicide and are already getting care at participating clinics.
Eugene, OregonAges 13–24 - NCT04732052Recruiting
tDCS treatment for adults with developmental disabilities and aggression
This trial tests whether a non-painful brain stimulation treatment (tDCS) can reduce aggressive behaviors in adults with developmental disabilities. It’s meant for people who have had aggression in the last month and can safely receive the stimulation.
Kingston, OntarioAges 18–65 - NCT07370311Recruiting
Support for Chinese American dementia caregivers on feeding choices
This study tests a decision aid designed to help Chinese American caregivers of older adults with dementia make feeding-related choices, especially near the end of life. It aims to support you in decisions about feeding options.
Austin, TexasAges 21–99 - NCT06531083Recruiting
Early monitoring and physical therapy to prevent jaw stiffness after radiation
This study tests whether a program of early monitoring and physical therapy can help prevent or reduce jaw stiffness (trismus) after radiation therapy for head and neck cancer. It is for patients who are about to start radiation and want to keep their jaw working well.
Edmonton, AlbertaAges 18 years+ - NCT07619599RecruitingPhase 1
PET Scan to Track Lung Cancer Treatment Response
This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.
Duarte, CaliforniaAges 18 years+ - NCT07668882Recruiting
Ultrasound brain stimulation for persistent stuttering
This study tests whether low-intensity focused ultrasound can change brain activity linked to stuttering. It may help people who have not had stuttering treatment in the past year.
Ann Arbor, MichiganAges 18–65 - NCT07217665Enrolling by invitationPhase 2
AADvac1 vaccine for progressive supranuclear palsy
This trial tests a vaccine called AADvac1 for people with progressive supranuclear palsy (PSP), a brain condition that affects movement and thinking. The study wants to see if the vaccine can slow the disease down.
San Francisco, CaliforniaAges 41–86 - NCT06581146Recruiting
Liver health study for boys with XLMTM
This study looks at how the liver works in boys with a serious muscle condition called XLMTM. It checks whether their liver is healthy, which may help doctors better understand the condition and guide future treatments.
Santa Monica, CaliforniaAges Up to 17 years - NCT05628207Recruiting
Test of an acceptable care-scaling plan for people with brain injury
This trial looks at a care approach to see if it is acceptable and workable for adults admitted to the hospital with a traumatic brain injury. It may help improve how care is scaled and delivered after TBI.
Minneapolis, MinnesotaAges 18 years+ - NCT07459764Recruiting
Body clocks study for women with regular periods
This study looks at how your body's internal clocks work together, especially in women. You may help researchers understand coordination between brain and body rhythms.
Stanford, CaliforniaAges 18–30 - NCT07636811RecruitingPhase 2
Mivelsiran for Early Alzheimer's in Down Syndrome
This trial tests a new drug called mivelsiran designed to slow early-stage Alzheimer's disease in adults with Down syndrome. The drug works by targeting amyloid, a protein that builds up in the brain and causes cognitive decline.
Maitland, FloridaAges 40–55 - NCT07583563Recruiting
Observational study of octreotide depot injections for acromegaly
This study watches how patients with acromegaly respond to octreotide, a medication given as injections under the skin. Researchers will collect information about how well the treatment works and any side effects you experience.
AachenAges 18 years+ - NCT07111637Recruiting
AI-assisted MRI for multiple sclerosis care
This trial is testing whether an artificial intelligence tool can improve the quality of MRI scans for people with MS. It aims to make scans faster, better, and more equitable for everyone in the NHS.
LondonAges 18–99 - NCT06138743RecruitingPhase 1/Phase 2
Investigational treatment for adult-onset myotonic dystrophy type 1
This trial is testing a new drug called SRP-1003 for people with myotonic dystrophy type 1 (DM1) who developed symptoms after age 12. The goal is to see if it can reduce muscle problems like myotonia (difficulty relaxing muscles) and improve daily function.
Liverpool, New South WalesAges 18–65 - NCT06131983RecruitingPhase 1/Phase 2
Study drug for facioscapulohumeral muscular dystrophy type 1
This trial is testing an investigational drug, SRP-1001, to see if it helps people with facioscapulohumeral muscular dystrophy type 1 (FSHD1), a condition that causes muscle weakness. The study will check if the drug is safe and if it can slow down the loss of muscle function.
Liverpool, New South WalesAges 16–70 - NCT07758543Recruiting
Facial exercises for improving symmetry in Bell's palsy
This trial tests whether special facial exercises can help people with Bell's palsy regain a more symmetrical face. The exercises focus on muscle control and nerve movement, and may improve recovery when done in the early months.
IslamabadAges 15–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.