Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT05747261RecruitingPhase 1/Phase 2
Single-dose gene therapy for children with spinal muscular atrophy
This trial tests a one-time gene therapy given through a vein to add a working SMN gene in children with spinal muscular atrophy (SMA). It mainly looks at safety first, and also checks early signs that treatment helps the disease.
MinskAges Up to 8 months - NCT06273176Recruiting
Surgery with or without brain mapping for recurrent glioblastoma
This study is testing whether using a special brain-mapping technique during surgery helps people with recurrent glioblastoma. It compares standard surgery to surgery with mapping to see if it leads to better outcomes for tumors near important brain areas.
San Francisco, CaliforniaAges Up to 90 years - NCT06272149RecruitingEarly Phase 1
Gene Therapy for Infants With Type 2 Gaucher Disease
This trial tests a new gene therapy (VGN-R08b) for infants with Type 2 Gaucher disease, a rare genetic condition that affects the brain and body. The goal is to see if the treatment is safe and can help improve symptoms.
Shanghai, Shanghai MunicipalityAges birth–2 years - NCT07869511Recruiting
Steroid injection behind the eye for light-damage to the retina
This study tests whether a steroid injection behind the eye (a retrobulbar injection) can help people whose retina (the light-sensing layer at the back of the eye) has been damaged by looking at a strong light source, like a laser or bright flash. The treatment aims to reduce swelling and vision problems that can follow such an injury.
Hangzhou, ZhejiangAges 6 years+ - NCT02753335Recruiting
Rehabilitation for complex regional pain syndrome
This study tests a comprehensive rehabilitation program for adults with complex regional pain syndrome (CRPS), a chronic pain condition usually affecting one arm or leg. It looks at how the program affects pain and brain function, aiming to improve daily life.
TromsøAges 18–70 - NCT02426398Recruiting
New brain wave test for early dementia diagnosis
This study tests a new brain wave (EEG) method to help diagnose Alzheimer's disease earlier. It may help find the disease sooner and could lead to better treatment planning.
Sheffield, S YorksAges 18 years+ - NCT07868796Recruiting
A closer look at inherited mitochondrial brain disease
This study collects medical information from people with mitochondrial leukoencephalopathy (a rare genetic disease that damages the brain's white matter) to learn how the disease progresses and how different gene changes affect symptoms. By joining, you can help researchers better understand the condition and improve future care for others.
MilanAges Any age - NCT04810871Recruiting
Surgery for brain tumors that may come back
This study tests whether removing a brain tumor early, before it shows signs of growing back, can help prevent a recurrence. If you have had treatment before and there is still some tumor left, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT07867899Recruiting
Preventing confusion after hip fracture surgery
This study tests whether a medication called dexmedetomidine, given during or after hip fracture surgery, can help prevent confusion (delirium) that sometimes occurs in older patients after surgery. If you are 65 or older and having hip fracture surgery, this treatment might help you recover more clearly.
AarhusAges 65 years+ - NCT07870577Recruiting
Nerve health during bladder cancer treatment
This study looks at nerve problems (peripheral neuropathy) in people with muscle-invasive bladder cancer who receive a combination of two drugs, enfortumab vedotin and pembrolizumab, before or after surgery. The goal is to understand how these treatments affect nerves and to help manage side effects.
Munich, BavariaAges 18 years+ - NCT07872670Recruiting
Virtual reality to help recovery after hip or knee replacement
This study uses virtual reality (a computer-generated 3D environment you wear a headset for) alongside your usual care to help with recovery after hip or knee replacement surgery. It may help reduce pain or improve how well you move after surgery.
Inverness, HighlandsAges 18 years+ - NCT07870044Recruiting
Virtual reality to boost body awareness
This study uses virtual reality to help people feel more connected to their body. It may benefit healthy people or those with spinal cord injury or stroke.
Bosisio Parini, LeccoAges 12–50 - NCT05176704Recruiting
Eye movement tests for Alzheimer's disease
This study looks at how people with Alzheimer's disease move their eyes compared to healthy people. The goal is to develop simple, non-invasive eye-tracking tests that could help diagnose Alzheimer's disease earlier and more accurately.
Montreal, QuebecAges 18 years+ - NCT05717699RecruitingPhase 1
Trial of a virus treatment for DIPG in children
This Phase 1 trial tests a lab-made cancer virus (Ad-TD-nsIL12) in children with DIPG whose tumor keeps growing after standard treatment. It mainly focuses on safety and how the treatment works, and it may help shrink or control the tumor by stimulating the immune system.
Beijing, Beijing MunicipalityAges 1–18 - NCT01574053Recruiting
Global Huntington’s disease registry for gene carriers and controls
This study builds a global record of people who carry the Huntington’s (HD) gene change and people who do not. By comparing them over time, researchers hope to better understand how HD begins and progresses.
Birmingham, AlabamaAges 18 years+ - NCT05805566Recruiting
Study of care for long COVID symptoms in adults
This study follows people who enter a specialized care pathway for long COVID (post-COVID syndrome) to better understand symptoms, needs, and outcomes. It may help improve how multidisciplinary care is organized for long COVID over time.
Pierre-BéniteAges 18 years+ - NCT05717712RecruitingPhase 1
Study virus treatment for newly diagnosed DIPG in children
This Phase 1 trial tests a type of cancer-fighting virus given directly into the tumor for children with newly diagnosed diffuse intrinsic pontine glioma (DIPG). The goal is to see if it can be delivered safely and to learn how the body responds to it.
Beijing, Beijing MunicipalityAges 1–18 - NCT05964764Recruiting
Check which head-injury guidelines work for children
This study tests and confirms Swedish/Norwegian guidelines for treating minor to moderate head injuries in children. It may help doctors decide the safest next steps after an injury, especially for whether and when to use scans and observation.
HaukelandAges Up to 17 years - NCT07872956Recruiting
Yoga app for home cancer rehab
This trial studies a yoga app designed with patient input to help people undergoing cancer treatment exercise at home. It aims to see if the app is practical and helpful for improving well-being during cancer care.
LinköpingAges 18 years+ - NCT07859488Recruiting
Delirium risk after cancer surgery
After surgery for cancer in the belly area, some older adults become confused or have memory problems. This study looks for early signs in the blood that might predict this, so doctors can help prevent it.
Istanbul, IstanbulAges 65 years+ - NCT06281145Recruiting
Stress reduction for breast or colon cancer patients
This study tests a stress-reducing program for people with breast or colon cancer. It uses a technique called heart rate variability biofeedback to help you manage stress during treatment.
BratislavaAges 18 years+ - NCT07853664RecruitingPhase 2/Phase 3
Dexamethasone and diclofenac gel for facial surgery pain
This study tests a gel containing two pain and swelling medicines applied to the skin after facial surgery or facial injury repair. The goal is to see if it provides better pain relief and less swelling than usual care.
DhamarAges Any age - NCT07871149Recruiting
Perimenopausal symptom study for women with sleep apnea
This study tests whether treating sleep apnea can help women with menopause-related symptoms. It uses a home sleep test to check for sleep apnea and may offer treatment options to improve sleep and quality of life.
Chicago, IllinoisAges 18–40 - NCT07869901Recruiting
Sleep and light therapy for recovery in the ICU
This study tests whether helping ICU patients sleep better and keeping their body clock on a normal day-night rhythm can improve recovery after surgery.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.