Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT06477952RecruitingPhase 1/Phase 2
Dronabinol for sleep apnea
This study tests whether dronabinol, a cannabis-like medicine, can help people with moderate sleep apnea breathe better at night. It may be an option for those who haven't found other treatments helpful.
Chicago, IllinoisAges Up to 65 years - NCT07758920RecruitingPhase 2
New tablet for long-term shingles pain
This trial tests a new tablet called HL-1186 for treating post-herpetic neuralgia (long-lasting pain after shingles). It compares the new drug to pregabalin, a standard treatment, to see if it's safer and more effective.
BeijingAges 18 years+ - NCT07758114Recruiting
Prenatal education on environmental exposures
This study provides education about everyday environmental exposures during pregnancy. It aims to help women make safer choices for their health and their baby's health.
Galveston, TexasAges 18 years+ - NCT07756775Recruiting
Comparing two imaging tests for stroke diagnosis
This study compares two imaging methods, magnetic resonance imaging (MRI) without contrast dye and a carotid ultrasound (Doppler), to see which one is better at finding blocked arteries in the neck that can cause strokes. The results may help doctors choose the best test for people who have had a stroke or a mini-stroke.
Sohag, Sohag GovernorateAges 18 years+ - NCT07458503Recruiting
Brain stimulation plus arm therapy for stroke recovery
This study tests a new combination treatment for people who had a stroke more than six months ago and still have arm weakness. It uses a gentle electrical current on the head (tDCS) along with a therapy that encourages use of the affected arm. The goal is to improve arm movement and daily function.
Belém, ParáAges 40–80 - NCT07757477Recruiting
Sunlight for vitamin D in kids with cerebral palsy
This study tests whether sunlight exposure can help raise vitamin D levels in young children with cerebral palsy. It aims to see if more sunlight can improve their health and well-being.
Jakarta Pusat, DKI JakartaAges 1–5 - NCT07435129RecruitingPhase 2
Study of apitegromab for people with FSHD
This study tests whether a drug called apitegromab can help improve muscle function in people with facioscapulohumeral muscular dystrophy (FSHD). It is for adults aged 18-60 who have mild to moderate symptoms and can walk or run 10 meters in 5 seconds or less.
Austin, TexasAges 18–60 - NCT07756905Recruiting
Motor control exercises with and without tape for sciatica
This study tests whether adding kinesio tape (a flexible, supportive tape) to a motor control exercise program helps reduce sciatica pain more than exercises alone. It may help improve movement and reduce pain in your leg.
SialkotAges 35–50 - NCT07757763Recruiting
Slow jogging for breast cancer survivors
This study looks at whether slow jogging (a gentle form of running) can help breast cancer survivors sleep better. You'll be asked to use a smartphone app to track your activity and sleep, and you may be assigned to a jogging group or a usual-care group.
Taipei, Taipei CityAges 20 years+ - NCT07758816Recruiting
Better treatments for Gaucher disease with lung or bone problems
This study looks at how standard treatments for Gaucher disease affect lung problems, bone damage, and parkinson-like symptoms. It aims to find better ways to treat these complications and improve quality of life.
New Haven, ConnecticutAges 3 months–75 years - NCT06656702RecruitingEarly Phase 1
Psilocybin for depression in amyotrophic lateral sclerosis
This trial tests whether psilocybin, a psychedelic drug, can safely help with depression in people with ALS. It also looks at how the drug affects your symptoms and quality of life over six months.
Baltimore, MarylandAges 18 years+ - NCT02257866Recruiting
Study of blood vessel inflammation over time
This study looks at different types of blood vessel inflammation (vasculitis) to learn more about why they happen and how they progress. By joining, you may help doctors better understand these conditions and improve future treatments.
Bethesda, MarylandAges 3 years+ - NCT06469801Recruiting
Portable MRI for brain injury in children on ECMO
This study uses a portable MRI to look for brain injuries in children on ECMO (a heart-lung support machine). It may help doctors detect problems early and improve care.
Kansas City, MissouriAges birth–17 years - NCT07227857RecruitingPhase 1/Phase 2
Study of a new medicine for children with KCNT1-related epilepsy
This study tests a new medicine (S230815) given by lumbar puncture (spinal tap) to see if it helps reduce seizures in children with a specific genetic cause of epilepsy. It is for children aged 2 to 12 who have not responded well to other treatments.
Orange, CaliforniaAges 2–12 - NCT07757178Recruiting
Dementia lived experiences study
This study explores the personal stories and experiences of people with dementia, their families, and caregivers to help improve care and support. Participation involves sharing your experiences in interviews or other tasks.
Nottingham, EnglandAges 18–99 - NCT07758270Recruiting
Brain scan study for multiple sclerosis treatment switch
This study looks at how a new pill for multiple sclerosis (MS) affects brain inflammation and immune cells. It may help people who are already taking an MS medication but want to switch to a different one.
St Louis, MissouriAges 40–70 - NCT04222413RecruitingPhase 1
Study of metarrestin for advanced solid tumors
This study tests an experimental drug called metarrestin for people with solid tumors that have spread or come back after standard treatment. It may help by targeting a protein involved in cancer cell growth.
Fairway, KansasAges 12–120 - NCT07357662Recruiting
Exercise video games for foot strength and balance in older adults
This study tests how playing fun exercise video games (exergames) can improve foot muscle activity, balance, and ability to move around in older adults who are otherwise healthy.
Tarsus, Mersi̇nAges 65–80 - NCT06085144Recruiting
Emgality for migraine in breastfeeding women
This trial studies how the migraine medication Emgality (galcanezumab) passes into breastmilk and whether it is safe for nursing babies. It may help new mothers who need migraine treatment while breastfeeding.
San Francisco, CaliforniaAges 18–45 - NCT05658497Recruiting
MS pregnancy registry for Vumerity (diroximel fumarate) exposure
This study collects information about pregnancies in people with multiple sclerosis (MS) who were exposed to Vumerity (diroximel fumarate) or who were not on MS medicines during pregnancy. It helps researchers understand pregnancy outcomes and safety in these situations.
Aurora, ColoradoAges Any age - NCT07759063Enrolling by invitation
Self-paced walking study for stroke or brain injury survivors
This study tests a new way to help people who have had a stroke or brain injury walk with a more even step. It uses a treadmill that adjusts to your own pace, which may improve your walking symmetry.
Omaha, NebraskaAges 19–75 - NCT05544526RecruitingPhase 1
CAR T cell treatment for brainstem spinal cord tumor in children
This Phase 1 trial tests CAR T cells designed to attack a specific target (GD2) on a rare childhood brain/spinal tumor called DMG with a certain gene change (H3K27M). It is mainly designed to check safety and early signs of effectiveness after prior treatments.
LondonAges Up to 16 years - NCT07727395RecruitingPhase 3
Clot-busting drug after successful clot removal for stroke
This trial tests whether giving a clot-busting drug (alteplase) directly into the brain artery after a successful clot removal improves recovery in people with severe stroke. It is for patients who have had a thrombectomy and still have a large blocked artery in the front of the brain.
An GiangAges 18 years+ - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.