Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT07115563Recruiting
Amino acid supplement test for Parkinson's disease
This trial tests if taking daily amino acid supplements helps people with Parkinson's disease. You need to be on stable Parkinson's medication for at least 3 months.
Farmington, ConnecticutAges 50–90 - NCT06064890RecruitingPhase 1/Phase 2
Gene therapy trial for genetic frontotemporal dementia
This trial tests a new gene therapy called AVB-101 for people with a specific genetic cause of frontotemporal dementia (FTD). The therapy is given as a one-time injection into the brain to potentially slow or stop the disease.
Columbus, OhioAges 30–75 - NCT07610564RecruitingPhase 1
Testing a New Treatment for Multifocal Motor Neuropathy
This study tests a new medicine called empasiprubart in adults with multifocal motor neuropathy (MMN), a rare condition affecting nerve function. The trial uses ultrasound to see if the medicine can help reduce nerve thickening and improve symptoms.
TbilisiAges 18 years+ - NCT05016908RecruitingTeam says not enrolling
Testing blood and other fluid markers in Duchenne or Becker
This study looks for signals in blood and other body fluids that may help track Duchenne or Becker muscular dystrophy. It may be helpful for patients by improving how future monitoring tests are developed.
Boston, MassachusettsAges 5 years+ - NCT06161519RecruitingPhase 1/Phase 2
PLX038 for brain tumors with MYC or MYCN changes
This study tests a new drug called PLX038 for people with brain or spinal cord tumors that have certain genetic changes (MYC or MYCN) or have come back after treatment. The drug is given as an infusion and targets tumor cells. The study aims to see if the drug is safe and effective for different types of these tumors.
Bethesda, MarylandAges 18–120 - NCT06688435RecruitingPhase 1
Immune cell therapy for hard-to-treat myasthenia gravis
This trial tests a new immune cell treatment (CAR T-cells) for people with generalized myasthenia gravis that has not improved with standard treatments. It aims to reduce symptoms by targeting and calming the immune system's attack on muscles.
JinanAges 18–65 - NCT05091242RecruitingPhase 2/Phase 3
Preventing agitation after anesthesia in babies up to 1 year old
This study tests a way to reduce post-surgery agitation (confusion or restlessness) in babies aged 3 to 12 months who need anesthesia for a procedure. The goal is to make recovery calmer and safer for your baby.
Perth, NedlandsAges 3 months–1 year - NCT07759791Recruiting
Life coaching after stroke to rejoin valued activities
This trial tests a coaching program that helps people who have had a stroke get back into activities they value, like hobbies or social outings. It may help you feel more connected and improve your quality of life.
Kingston, OntarioAges 18 years+ - NCT07143669Recruiting
Screening study for mast cell disease with KIT mutation
This study looks for a specific gene change (KIT D816V) in people with certain allergic reactions or related conditions. It aims to find those who might benefit from future treatments targeting this mutation.
Birmingham, AlabamaAges 18 years+ - NCT07759310Recruiting
Teamwork training for ICU nurses to reduce delirium
This study is testing a training program that helps ICU nurses improve how they prevent and manage delirium (a state of confusion that can happen in hospital). If you are an ICU nurse, this training could help you feel more confident in caring for patients with this condition.
Pisa, PIAges 18 years+ - NCT07759440Recruiting
Two ways to fix a broken eye socket
This study compares two methods surgeons use to fix a broken bone around the eye (orbital fracture). The goal is to see which approach gives patients a better recovery with fewer side effects.
Alexandria, Outside US and CanadaAges 20–50 - NCT07761507Recruiting
Ear stimulation to help wake up after brain bleed surgery
This trial tests a gentle ear stimulation device that may help people regain consciousness after surgery for a brain bleed. It is done while the person is in the hospital and may improve recovery.
BeijingAges 18–75 - NCT07761871Recruiting
Exercise and diet for people with melanoma on immunotherapy
This trial looks at whether adding a program of exercise and nutrition changes can improve quality of life and treatment outcomes for people with melanoma who are starting immunotherapy. If you qualify, you would take part in a structured plan to see if these lifestyle changes help.
LjubljanaAges 18 years+ - NCT07505836RecruitingPhase 3
Meningitis vaccine trial for toddlers aged 12–23 months
This study tests a vaccine that protects against four common types of meningitis (groups A, C, Y, and W135) in toddlers aged 12–23 months. It helps researchers see if the vaccine is safe and works well for young children.
Nanning, GuangxiAges 1 year–1.9 years - NCT06710483Recruiting
Dental care help for youth with disabilities
This study aims to make dental visits easier for youth with intellectual or developmental disabilities. It tests a program to support both patients and their dental providers.
Boston, MassachusettsAges 12–18 - NCT07703137Enrolling by invitation
NAD Supplement for Parkinson's Disease Study
This study tests whether a supplement called NAD (a natural substance that helps cells produce energy) can improve symptoms in people with Parkinson's disease. You would take the supplement daily for several weeks, and researchers will check your movement, thinking, and overall well-being.
Oklahoma City, OklahomaAges 55–85 - NCT07689773RecruitingPhase 2
Can brain training improve smell loss?
This trial tests a type of brain training (called TNS) that uses mild electrical pulses to help improve your sense of smell. If you have smell loss and want treatment, this study may see if TNS can help.
Charleston, South CarolinaAges 18–80 - NCT07505810RecruitingPhase 3
Meningitis vaccine trial for infants 3-5 months old
This trial tests a vaccine that protects against four types of meningococcal bacteria (groups A, C, W, and Y) in healthy babies aged 3 to 5 months. The vaccine is given to help prevent meningitis and other serious infections.
Nanning, GuangxiAges 3 months–5 months - NCT05639478Recruiting
Foot care and exercise program for people with diabetes
This trial tests whether a structured foot-care and exercise program in primary care helps adults with diabetes. It may help you stay more active and reduce foot problems by teaching daily care and safe movement.
Limeira, São PauloAges 18 years+ - NCT06604884Recruiting
Pipeline Vantage device study for brain aneurysms
This study follows people who receive the Pipeline Vantage device to treat a brain aneurysm. It helps doctors learn more about how well the device works in real-life use.
Jacksonville, FloridaAges 22 years+ - NCT05922514Recruiting
Registry for people with spinal fluid leak headache
This registry study collects information from people diagnosed with spontaneous intracranial hypotension (a type of spinal fluid leak headache) to better understand the condition. You may help by providing MRI results and follow-up information over about 3 months.
Rochester, MinnesotaAges 18 years+ - NCT06465199RecruitingPhase 1/Phase 2
Eflornithine and AMXT 1501 for Advanced Childhood Cancers
This trial tests a combination of two drugs (eflornithine and AMXT 1501) for children and young adults with certain types of cancer that have relapsed or not responded to standard treatment, or for a specific brain tumor (DIPG) at diagnosis. The goal is to see if this drug pair is safe and effective.
Birmingham, AlabamaAges Up to 26 years - NCT07713758RecruitingPhase 1
How the body handles repinatrabit with liver or kidney issues
This trial checks how repinatrabit is processed in people with moderate liver problems or severe kidney problems compared to healthy adults. It helps doctors understand if the dose should be adjusted for these conditions.
Miami, FloridaAges 18–65 - NCT07593391RecruitingPhase 3
NNZ-2591 Treatment for Children with Phelan-McDermid Syndrome
This study tests whether a medication called NNZ-2591 can help children with Phelan-McDermid syndrome, a rare genetic condition that affects brain development and learning. Researchers want to see if this drug can improve how children with this condition develop and learn.
Glendale, CaliforniaAges 3–12
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.