Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT04602325Recruiting
Blood and brain injury biomarker study for inherited metabolic disorders
This trial studies blood and other measurable signs (biomarkers) that may reflect brain injury after certain inherited metabolic conditions. Results may help doctors better detect and understand brain effects from these illnesses, especially episodes that affect the brain.
Washington D.C., District of ColumbiaAges 7–18 - NCT06243003RecruitingPhase 1/Phase 2
Brain radiation for SCLC with brain metastases
This trial tests a new radiation approach for people with small cell lung cancer that has spread to the brain. It combines whole-brain radiation that avoids the memory centers, followed by focused radiation to the tumors, while you also receive standard chemotherapy and immunotherapy.
ShanghaiAges 18 years+ - NCT06087276RecruitingPhase 3
Study of ulixacaltamide for essential tremor
This study tests whether the drug ulixacaltamide can safely reduce tremors in people with essential tremor, a condition that causes shaking of the hands and arms. It is a phase 3 trial, meaning it is in the final stages of testing before possible approval.
Morgantown, West VirginiaAges 18–85 - NCT05199376Recruiting
Cryotherapy treatment for painful, hard-to-remove NF1 tumors
This trial tests whether freezing treatment done through the skin (cryotherapy) can reduce pain and discomfort from certain non-cancer NF1 tumors that can’t be safely removed. You may be able to join if you’re an adult with NF1, a painful or bothersome benign lesion, and can safely undergo procedures like MRI.
LyonAges 18 years+ - NCT02630589Recruiting
Brain implant for severe one-sided ringing that harms daily life
This trial tests an implant that sends sound signals to the brainstem to reduce severe ringing in one ear. It may help people whose one-sided tinnitus has lasted over a year and did not improve with usual treatments like hearing aids and CBT.
GroningenAges 18 years+ - NCT05474066Recruiting
Testing brain function changes before and after deployment
This study looks at how the brain’s attention and information-processing skills change around major military changes. It may help researchers better understand who is affected and how to support performance and recovery.
Ottawa, OntarioAges 18–65 - NCT06121232Recruiting
Nerve stimulation study for chemotherapy-related nerve pain
This study tests a nerve stimulation treatment to see if it can help reduce pain and improve feeling in the feet for people with nerve damage caused by chemotherapy. You will receive the treatment and have some tests to measure how your nerves are working.
Houston, TexasAges 18 years+ - NCT07858708Enrolling by invitation
Vision problems after brain injury
This study looks at vision problems that can happen after a brain injury, like a stroke, traumatic brain injury, or brain tumor. The researchers want to understand how these vision issues affect daily life, which could help improve care.
Prague, Česká RepublikaAges 18–85 - NCT07858292Enrolling by invitation
Fava bean peptides and strength training for seniors
This study tests whether a supplement made from fava beans, combined with a supervised strength training program, can help improve muscle health in older adults. If you are 60 or older and able to do light exercise, you may be able to join.
Maringá, ParanáAges 60 years+ - NCT07858864Recruiting
GLP-1 weight loss drugs and muscle health in obesity
This study looks at how GLP-1 receptor agonist drugs (used for weight loss) affect muscle mass and strength in people with obesity who do not have diabetes. It may help understand if these medications impact muscle health.
Istanbul, KucukcekmeceAges 18 years+ - NCT07871487Recruiting
Brain protein changes after hip or knee replacement surgery
This study looks at whether having hip or knee replacement surgery with spinal anesthesia affects certain proteins in the brain that are linked to memory and thinking. It compares people having surgery with people who have arthritis but are not having surgery, to help understand if the surgery causes any short-term brain changes.
UppsalaAges 55–75 - NCT07868614Recruiting
Comparing brain signal recordings during deep brain stimulation surgery
This study compares a new device for recording brain signals during deep brain stimulation (DBS) surgery with the standard equipment. DBS is a treatment for movement disorders like Parkinson's disease that uses a device to send electrical signals to specific parts of the brain.
Rochester, MinnesotaAges 18 years+ - NCT07866846Recruiting
Ketogenic diet for blood sugar side effects of pasireotide in acromegaly
This study tests whether a low-carbohydrate ketogenic diet can help manage high blood sugar caused by the medication pasireotide, which is used to treat acromegaly. If you are being considered for or already taking pasireotide and your blood sugar is rising, this diet might help you avoid or reduce the need for diabetes medications.
Leiden, South HollandAges 18 years+ - NCT04390646RecruitingPhase 2/Phase 3
Hormone treatment to study thinking in Down syndrome
This trial studies whether a GnRH hormone treatment can improve thinking and memory in people with Down syndrome. It also checks safety and whether the treatment affects brain-related changes seen on MRI.
Lausanne, Canton of VaudAges 16–50 - NCT06030349Recruiting
Breathing support for kids with Down syndrome and sleep apnea
This trial looks at how well non-invasive breathing machines help children with Down syndrome who have obstructive sleep apnea. It tracks their health and sleep over time to see if the treatment works and improves daily life.
DublinAges 6 months–16 years - NCT06253754Recruiting
Study of headache after spinal tap
This trial looks at why some people get a headache after a spinal tap and how treatment might help. It may be an option if you are between 20 and 40 and have this kind of headache.
Umeå, Västerbotten CountyAges 20–40 - NCT06253962Recruiting
Can carotid artery scans predict heart disease?
This study looks at whether ultrasound scans of the carotid artery (the main artery in your neck) can help predict blockages in the heart arteries. If you are getting both a carotid ultrasound and a heart angiogram, you may be able to join.
ShanghaiAges 14–90 - NCT05315752Recruiting
Body fat changes after CPAP-treated sleep apnea improves
This study looks at how bariatric (weight-loss) surgery may change body fat and body shape in people with severe obstructive sleep apnea who use CPAP. It aims to understand what may improve when sleep apnea is better controlled after surgery.
BrusselsAges 18–99 - NCT06255210RecruitingPhase 2
Chemotherapy before surgery for olfactory neuroblastoma
This trial tests whether giving chemotherapy before surgery can help treat olfactory neuroblastoma, a rare type of nose cancer. It aims to see how safe and effective this approach is for people with early to advanced tumors that have not spread to other parts of the body.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT00455104Recruiting
Fabry disease registry for Canadians and eligible adults
This study is a national registry that collects health and medical information from people with Fabry disease. It helps researchers better understand the condition and plan future care and studies.
Calgary, AlbertaAges 5–85 - NCT05638724Recruiting
Long COVID health registry for people of all ages
This study builds a health registry to learn how long COVID affects children, teens, and adults over time. It may help by improving understanding of symptoms and care, even if it does not test a new drug.
Munich, BavariaAges Any age - NCT02829684Recruiting
Register for people with Prader-Willi syndrome
This is a patient registry that collects information about people with Prader-Willi syndrome. It may help researchers better understand the condition and plan future studies.
ToulouseAges Any age - NCT07872839Enrolling by invitation
Study of arm muscle activity in spinal cord injury
This study looks at how arm muscles work together in people with spinal cord injury. It involves mild electrical stimulation to help understand muscle control, which may lead to better treatments.
TaipeiAges 20–65 - NCT03217578Recruiting
Newborn screening for spinal muscular atrophy in Taiwan
This trial offers testing for spinal muscular atrophy (SMA) to newborns. It aims to identify SMA early so families and doctors can act sooner if results suggest the condition.
Kaohsiung CityAges birth–2 weeks
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.