Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT04957537Recruiting
Speech and meaning therapy for primary progressive semantic aphasia
This study tests a “semantic rehabilitation” program—therapy focused on improving word meaning and understanding—for people with primary progressive semantic aphasia. If you qualify, it may help slow or improve language difficulties and daily communication.
ToulouseAges 18–100 - NCT06015451Recruiting
Exercise for concussion symptoms and headache
This trial tests whether a carefully supervised exercise program can help people who still have headaches or other symptoms weeks after a mild head injury. If you get symptoms when you try to be active, this study may offer a structured way to help you recover.
TrondheimAges 18–65 - NCT07100730RecruitingPhase 3
A new drug for recurrent glioblastoma vs standard care
This trial tests a new targeted drug, TLX101-Tx, added to standard care for people with glioblastoma that has come back after initial treatment. It aims to see if the combination helps control the tumor better than standard care alone.
Gold Coast, QueenslandAges 18 years+ - NCT07524049Recruiting
Giving Children a Voice in Pediatric Anesthesia
This study listens to what children, their families, and doctors think about anesthesia care (the medication that puts you to sleep during surgery). Researchers want to understand how to make the experience better and less scary for kids having procedures.
Aarau, Canton of AargauAges 6 years+ - NCT07187687Recruiting
Early minimally invasive clot removal for brain hemorrhage
This study tests if removing a large brain clot early using a small tube and clot-dissolving medicine can improve recovery after a hemorrhagic stroke. It is for people with a moderate to large bleed who can start treatment within 12 hours of symptoms.
Guangdong, YuexiuAges 18 years+ - NCT06747884Recruiting
Study for children with myotonic dystrophy
This study looks at how to best measure muscle health and function in children with myotonic dystrophy. It may help prepare for future treatment trials.
Little Rock, ArkansasAges 3–17 - NCT07275047Recruiting
Comparing two pain blocks after lung surgery
This study compares two ways to manage pain after chest surgery (thoracotomy). One method is a single-shot paravertebral block and the other is a new type of block. The goal is to see which provides better pain relief with fewer side effects.
BursaAges 18–65 - NCT07585864Recruiting
Home Activity Monitoring for Older Women
This study uses sensors in your home to track how you perform everyday tasks like cooking and cleaning. Researchers want to better understand how older adults stay active and independent in their daily lives.
Pittsburgh, PennsylvaniaAges 75 years+ - NCT07758660Enrolling by invitationPhase 2
Brain scan study for Alzheimer's research
This study uses brain scans (PET) to look at changes in the brain that may be related to memory problems or Alzheimer's disease. It aims to improve understanding of the disease and may help develop better treatments.
New York, New YorkAges 50 years+ - NCT07690982Recruiting
Posture and movement study for stroke survivors
This study uses a device called PhysioMaster to measure posture and range of motion in people who have had a stroke. It aims to help understand and improve recovery after a stroke.
IstanbulAges 40–70 - NCT07598708RecruitingPhase 2/Phase 3
Cleminorexton for Narcolepsy: A New Treatment Study
This study tests whether a new medication called cleminorexton helps people with narcolepsy (a condition causing severe daytime sleepiness) sleep better and feel more alert. You would take this medication instead of your current narcolepsy drugs for several months to see if it works.
Colorado Springs, ColoradoAges 18–70 - NCT06666348RecruitingPhase 1/Phase 2
Mirdametinib plus vinblastine for untreated low-grade glioma
This trial tests a combination of two drugs (mirdametinib and vinblastine) for children and young adults with a type of slow-growing brain tumor called low-grade glioma that has certain genetic changes. It may be an option for people who have not received any previous treatment for their tumor.
Calgary, AlbertaAges 2–25 - NCT05201534Recruiting
Math and thinking skills training for school-age children
This trial studies interventions to improve math and cognitive (thinking) skills in elementary school children. It includes both children with math learning difficulties and typically developing children, using tests and MRI brain scans for those who can participate.
Palo Alto, CaliforniaAges 6–12 - NCT07011732RecruitingPhase 3
Testing a drug for Alzheimer's-related agitation
This study tests an experimental drug (KarXT) to see if it safely reduces agitation in people with Alzheimer's disease. It may help if you or your loved one experiences restlessness, aggression, or irritability related to Alzheimer's.
Scottsdale, ArizonaAges 55–90 - NCT07580365Recruiting
Virtual Reality Training for Kids With Muscle Diseases
This study tests whether a virtual reality-based exercise program can help children and teens with diagnosed muscle diseases improve their strength and function. Participants use a special exercise bike while wearing a VR headset to make training more engaging.
Bosisio Parini, LCAges 6–18 - NCT07444450RecruitingPhase 3
Study of salanersen for babies with SMA previously treated with gene therapy
This study tests a new medicine called salanersen in babies who have already received gene therapy for SMA. It aims to see if adding salanersen is safe and effective.
Flower Mound, TexasAges birth–7 months - NCT07218094Enrolling by invitation
Exosuit walking study for chronic stroke survivors
This study tests a robotic leg suit (exosuit) to help improve walking after a stroke. You may be eligible if you had a stroke more than 6 months ago and still have trouble walking safely.
Boston, MassachusettsAges 18 years+ - NCT07131696Recruiting
Vagus nerve stimulation for brain bleeding complication
This trial tests if a nerve stimulation device can prevent a dangerous blood vessel spasm after a brain aneurysm bleed. It may help reduce damage and improve recovery.
Birmingham, AlabamaAges 18–65 - NCT07549022RecruitingPhase 1/Phase 2
Testing BMS-986504 for Unresectable Nerve Sheath Tumors
This study tests whether a new drug called BMS-986504 is safe and effective for treating malignant peripheral nerve sheath tumors (MPNST) that cannot be surgically removed. The drug targets a specific genetic change (MTAP deletion) found in these tumors.
Cleveland, OhioAges 12 years+ - NCT07750392Recruiting
Dry needling and gentle laser therapy for recent neck pain
This trial tests two therapies—dry needling (thin needles into muscle knots) and low-level laser/microcurrent (gentle energy) treatment—alone or combined, to relieve acute neck pain from muscle knots (myofascial pain). It aims to reduce pain and improve function for people with recent onset symptoms.
Denpasar, BaliAges 20–45 - NCT07699094Recruiting
Predicting blood pressure changes in spinal cord injury
This study uses a simple finger sensor to monitor blood pressure regulation in people with spinal cord injury. It aims to find a new way to predict and manage blood pressure issues.
The Bronx, New YorkAges 18–75 - NCT07108387RecruitingPhase 2
Stopping or reducing tocilizumab for well-controlled giant cell arteritis
This study compares stopping tocilizumab (Actemra) completely versus reducing the dose in people whose giant cell arteritis has been well controlled for at least a year. The goal is to find out which approach keeps the disease in remission while reducing medication side effects.
Atlanta, GeorgiaAges 50 years+ - NCT07754747Recruiting
Balance training after stroke
This trial compares two types of balance exercises to see which one better improves balance, posture, and reduces the risk of falling in people who had a stroke at least 6 months ago.
RawalpindiAges 40–70 - NCT07694687Recruiting
Studying a tool to spot confusion in intensive care patients
This study tests a new way to check for delirium (sudden confusion) in patients staying in the intensive care unit (ICU). It also looks at how family members can help spot these changes, so the care team can help sooner.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.