Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06809517RecruitingPhase 1/Phase 2
Study of a new antibody plus chemotherapy for leptomeningeal metastasis
This trial tests a combination treatment for cancer that has spread to the lining of the brain and spinal cord (leptomeningeal metastasis). It uses an antibody given directly into the spinal fluid along with a chemotherapy drug, with the goal of targeting the cancer more effectively.
Huizhou, GuangdongAges 21–75 - NCT06809803RecruitingPhase 2
Extended-release sodium oxybate for children with narcolepsy
This trial tests an extended-release medicine (sodium oxybate) to see if it helps children with narcolepsy type 1 feel less sleepy during the day. It is only for children who are seen at the Stanford Sleep Clinic and have a clear diagnosis.
Redwood City, CaliforniaAges 7–17 - NCT06809842Recruiting
Nerve blocks for pain after knee surgery
This study compares two nerve blocks—one to a muscle nerve and one to a skin nerve—to see which works better for pain after knee surgery. If you're having knee surgery, these blocks could help you recover with less pain and fewer side effects.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06810219Recruiting
Brain-computer interface study for ALS communication
This study tests a brain-computer interface (BCI) that uses augmented reality glasses to help people with late-stage ALS communicate. You wear a headset that reads your brain signals and lets you select words or phrases on a screen, giving you a new way to talk to others.
Santa Barbara, CaliforniaAges 18 years+ - NCT06810336RecruitingEarly Phase 1
Pain control after brain surgery: methadone vs remifentanil
This trial compares two medicines, methadone and remifentanil, to see which one works better for pain after brain surgery. It may help improve your recovery and comfort.
Charlottesville, VirginiaAges 18–65 - NCT06810505RecruitingPhase 3
Oral atogepant for preventing migraines in teens
This trial tests an oral medication called atogepant to see if it can prevent migraines in teens aged 12–17. It aims to reduce how often migraines happen and track any side effects.
Huntsville, AlabamaAges 12–17 - NCT06810544RecruitingPhase 1/Phase 2
Study of TNG456 for tumors with MTAP loss
This trial tests a new drug called TNG456, alone or with another drug (abemaciclib), for people whose tumors have lost the MTAP gene. It aims to see if the combination can shrink tumors or slow their growth.
Scottsdale, ArizonaAges 18 years+ - NCT06810817Recruiting
Brain stimulation and talk therapy for post-stroke fatigue
This trial tests whether a combination of gentle brain stimulation (tDCS) and a talking therapy program can help reduce fatigue after a stroke. It aims to find a safe, non-drug way to improve energy and quality of life for stroke survivors.
Hong KongAges 50–80 - NCT06810960Recruiting
Leqembi use in South Korean Alzheimer's patients
This study follows people with Alzheimer's who are already taking Leqembi (lecanemab) after being in the JOY-ALZ study. It collects medical information to check how the treatment works in real-world use.
Nutley, New JerseyAges 19 years+ - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06811610Recruiting
Testing a hearing device with noise-canceling headphones
This trial tests if a portable hearing device using active noise-canceling headphones can accurately measure hearing. It might help by making hearing tests more convenient and accessible.
Xi’an, ShanxiAges 6 years+ - NCT06813235Recruiting
Sleep improvement program for Chinese cancer survivors
This study tests a step-by-step program to help Chinese cancer survivors with mild to moderate sleep problems. The program adjusts to your needs and aims to improve your sleep without strong medication.
Hong KongAges 18 years+ - NCT06813352Recruiting
Using facial expressions to recognize pain in fibromyalgia
This study uses artificial intelligence to look at facial expressions and other body signals to help recognize pain in people with fibromyalgia. It may lead to better ways to measure and treat pain.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06813443Recruiting
Studying cardiomyopathy to find who needs a heart transplant
This study is looking at people with cardiomyopathy to understand which patients are most in need of a heart transplant. By joining, you will help doctors learn more about critical cases and improve care for heart muscle disease.
Bologna, Emilia-Romagna/BolognaAges 12 years+ - NCT06813586Recruiting
Study of cerebral palsy cases in Italy
This study observes children with cerebral palsy to better understand how common it is in Italy. It may help improve care and resources for people with CP.
Brindisi, ApuliaAges 4–18 - NCT06813651RecruitingPhase 2
TBO-309 for stroke with tandem blockage
This trial tests whether adding TBO-309 to standard treatment helps people having a stroke caused by two blockages (one in the neck, one in the brain). It may limit brain damage and improve recovery.
Newcastle, New South WalesAges 18 years+ - NCT06813612Recruiting
Play therapy for kids with specific epilepsy types
This trial tests if a play-based cognitive behavioral therapy can help children ages 6 to 10 with certain types of epilepsy. It may offer a new way to support their emotional and behavioral well-being.
PaviaAges 6–10 - NCT06813677Recruiting
Innsbruck Health Promotion Program
This study is a health promotion program for people living in the Innsbruck area. It aims to help participants improve their overall health and well-being.
InnsbruckAges 18 years+ - NCT06813937Recruiting
Magnetic stimulation for feeling in upper limb amputation
This study tests whether magnetic stimulation can improve sensation in people who have lost an upper limb. It may help restore feeling in the residual limb.
MoscowAges 18–65 - NCT06814015Recruiting
Self-balancing exoskeleton for spinal cord injury
This trial tests a self-balancing exoskeleton (a wearable robotic device) to help people with spinal cord injury stand and walk. It is for people with injury at or above T6, at least 6 months past injury, and a caregiver who can help during the study visits.
West Orange, New JerseyAges 18 years+ - NCT06814665Recruiting
Better diagnosis and care after a first seizure
This study aims to improve how doctors diagnose and treat people after their first suspected seizure. It may help if you've had a recent event that might have been a seizure and haven't been diagnosed with epilepsy before.
BergenAges Any age - NCT06815133Recruiting
Study of zilucoplan in French patients with myasthenia gravis
This trial is for people in France with myasthenia gravis who are already taking zilucoplan. It tracks how well and how safely the medicine works over 3 months in everyday practice.
Nice, Alpes MaritimesAges 18 years+ - NCT06815263Recruiting
Listener training to understand speech in Parkinson's
This trial tests a listener training program to help people better understand speech that is hard to understand due to Parkinson's disease. It may help if you have Parkinson's and a speech problem called hyperkinetic dysarthria.
Tallahassee, FloridaAges 18 years+ - NCT06815302Recruiting
Improving turning and freezing in Parkinson's disease
This study tests whether a 6-week exercise program can help people with Parkinson's disease who experience freezing of gait. You would exercise three times a week to see if it reduces freezing and improves turning.
Tempe, ArizonaAges 50–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.