Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06815432RecruitingPhase 1
CAR T cells for recurrent glioblastoma that makes GPC3
This trial tests a treatment made from your own immune cells, called CAR T cells, which are engineered to find and attack brain tumor cells that have a marker called GPC3. It is for patients whose glioblastoma has come back and who are already scheduled to have another surgery to remove the tumor.
Houston, TexasAges 21–70 - NCT06816199Recruiting
Hyperbaric oxygen for traumatic brain injury recovery
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) helps people recover from traumatic brain injury. It aims to see if this treatment is safe and can improve healing for patients starting rehabilitation.
Hangzhou, ZhejiangAges 18–90 - NCT06816641Recruiting
Surgery for spontaneous brain bleed: outcomes and factors
This trial studies how well surgery works for people who have a spontaneous brain bleed (not from injury) and looks at factors that might affect recovery. It may help doctors better predict who benefits from surgery.
SohagAges 20–70 - NCT06816836Recruiting
Measuring leg muscle mass to predict hospital stay after cancer surgery
This study uses ultrasound to measure leg muscle mass before surgery for gynecologic cancers, to see if it can predict how long you'll need to stay in the hospital after the operation.
Kolkata, West BengalAges 50–99 - NCT06817018RecruitingPhase 2
Ginger root extract for chronic sciatica pain
This study tests whether a ginger root extract can reduce pain in people with long-term sciatica. If you have had sciatic pain for at least 3 months and are not on blood thinners, you may be able to join.
Lubbock, TexasAges 18–85 - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT06817382RecruitingPhase 1
Gene therapy for young boys with Duchenne muscular dystrophy
This study tests a one-time gene therapy given by injection into the spinal fluid (intrathecal) for boys with Duchenne muscular dystrophy. It aims to see if the treatment is safe and how it spreads in the body, and may offer a new way to slow the disease.
Little Rock, ArkansasAges 2–4 - NCT06817434Recruiting
Statin treatment for Moyamoya disease study
This study tests if statins (cholesterol-lowering drugs) can help people with Moyamoya disease. The trial will follow patients who receive either surgery or standard care to see if adding a statin improves outcomes.
Beijing, ChinaAges 18–60 - NCT06817642Recruiting
Language recovery in stroke patients in intensive care
This study tests a new language assessment tool to predict how well stroke patients may recover their ability to speak and understand language. It may help identify who could benefit from early speech therapy.
CréteilAges 18–85 - NCT06817707Recruiting
Bladder function study in CANVAS patients
This study looks at bladder problems in people with CANVAS, a rare genetic condition that affects nerves. You will have an ultrasound of your bladder and a test to measure your urine flow.
Nice, Alpes MaritimesAges 18 years+ - NCT06817876Recruiting
Care Buddy: Helping dementia caregivers find support
This study tests a new app called Care Buddy that connects family caregivers of people with dementia to community resources. You'll use the app and share your feedback, which could help make caregiving easier.
Singapore, SingaporeAges 21–80 - NCT06817941Recruiting
Speech and arm exergame for children with cerebral palsy
This study tests a fun 'exergame' that combines speech exercises with arm movements for children with cerebral palsy. It may help improve coordination and communication.
Newark, New JerseyAges 8–17 - NCT06818240Recruiting
Can brain stimulation improve walking after stroke?
This study tests whether a gentle electrical current applied to the scalp (called tDCS) can improve your ability to walk while doing a second task, like talking or carrying something. It is for people who have had a stroke and can walk on their own.
Hong Kong, ChinaAges 50–80 - NCT06818409Recruiting
Blood test to predict confusion after hip fracture surgery
This study looks at a simple blood test called CALLY (CRP-Albumin-Lymphocyte) to see if it can predict which older adults might become confused after hip fracture surgery. The goal is to identify those at risk early so doctors can take steps to prevent or manage delirium.
Ankara, KeçiörenAges 65 years+ - NCT06818838RecruitingPhase 1/Phase 2
Gene therapy for Type 1 Gaucher disease
This study tests a new gene therapy called LY-M001 for adults with Type 1 Gaucher disease. It aims to help the body produce the missing enzyme and reduce symptoms like low blood counts or enlarged organs.
Guangzhou, GuangdongAges 18–60 - NCT06818864RecruitingPhase 1
Deep brain stimulation for memory after brain injury
This trial tests if deep brain stimulation (DBS) can improve memory and thinking for people who have had a traumatic brain injury. DBS uses a small device placed in the brain to send gentle electrical pulses.
Toronto, OntarioAges 18–70 - NCT06819124Recruiting
Study on interactions between people with ALS and their caregivers
This study looks at how people with ALS and their caregivers talk and interact with each other. It may help researchers understand communication challenges and improve support for both.
University Park, PennsylvaniaAges 18–90 - NCT06819475Recruiting
Muscle health study for childhood leukemia survivors
This study uses imaging to look at how well the mitochondria (the tiny power plants inside your muscle cells) are working. It compares survivors of childhood leukemia who have low muscle mass to healthy volunteers, to understand muscle health and find ways to help.
Memphis, TennesseeAges 18 years+ - NCT06819657Recruiting
Remote ischemic conditioning after aneurysm surgery
This trial tests a safe, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your leg) to see if it helps brain recovery after aneurysm surgery. It might reduce secondary damage and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06819670RecruitingPhase 2
Preventing infantile spasms from coming back
This trial tests whether a longer course of steroids can keep infantile spasms from returning in babies who have already responded to standard treatment. It may help reduce the chance of relapse.
Los Angeles, CaliforniaAges 2 months–1.5 years - NCT06819683RecruitingPhase 1
Testing a new oxygen sensor in people with and without mitochondrial myopathy
This study tests a tiny sensor that measures oxygen levels in muscle. It will help researchers understand how oxygen is used during exercise. If you have mitochondrial myopathy or are a healthy volunteer, you might be able to join.
Philadelphia, PennsylvaniaAges 18–65 - NCT06820398Recruiting
Exercise program for kids with cerebral palsy
This trial tests a special exercise program that combines strength training with resistance for children and teens with cerebral palsy. The goal is to see if it helps improve movement, strength, and daily function.
ValenciaAges 10–18 - NCT06819956RecruitingPhase 3
Lower-dose ketorolac for pain in the ICU
This trial tests whether a lower dose of the pain medicine ketorolac can safely control pain for people in the intensive care unit (ICU). If you are in the ICU and have pain, this study might help find a better way to treat it.
Edmonton, AlbertaAges 18 years+ - NCT06820008Recruiting
Using smartphones to track physical changes in ALS
This study uses smartphone apps and digital tools to track physical changes in people with ALS. It aims to better understand how the disease affects daily function, which could help improve future care.
Dublin, DublinAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.