Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT05449119Recruiting
Study links gut health, diet, and thinking and movement in seniors
This study looks at how differences in gut bacteria and nutrition may relate to changes in thinking and movement in people over 75 who have a reduced appetite (“small eaters”). It may help doctors better understand what could be contributing to these problems and how nutrition might play a role.
DijonAges 75 years+ - NCT05412823Recruiting
Testing neurologic function after emergency breathing tube placement
This study looks at how well a person’s brain and nerve function works after doctors place an emergency breathing tube. It may help improve care after urgent intubation, especially for people who were functioning fairly well before the event.
JeddahAges 18 years+ - NCT05258396Recruiting
Remyelination study for teens with multiple sclerosis
This study tests whether the brain may “repair” itself (re-myelinate) in children and teens with multiple sclerosis. It uses brain MRI to look for changes and may help clinicians better understand how to treat MS in younger people.
Le Kremlin-BicêtreAges 12–18 - NCT05254353Recruiting
Compare spinal fluid sampling spots in people with brain drains
This study compares different locations for taking small samples of fluid from an external brain drain. It aims to learn which sampling spot gives the most useful results, while helping clinicians improve care for people needing this drain.
LeuvenAges Any age - NCT05237232Recruiting
MRI study of blood vessel changes after ECMO in infants
This study uses a brain MRI with a special blood-vessel scan to see how circulation changes after a life-support machine called ECMO in young children. It may help doctors better understand what happens in the brain after ECMO and improve care.
ParisAges Up to 17 years - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT05026060Recruiting
Test for brain blood flow imaging in children with artery disease
This study uses a special MRI method to measure how much blood is reaching the brain in children with certain artery problems. It may help doctors better assess these conditions during routine care and imaging.
ParisAges Up to 18 years - NCT05020158Recruiting
Family Talk support after a serious illness in the family
This trial tests a “Family Talk” support program for families dealing with a child’s life-threatening or life-limiting illness. It aims to help families talk and cope together during the early period after diagnosis or relapse.
StockholmAges 6 years+ - NCT04861818Recruiting
Testing how exercise timing affects memory in healthy young adults
This study looks at whether the time of day you exercise changes how well you remember things. It asks healthy young adults to do controlled exercise over two lab visits and avoids exercise for a few days to compare results.
Greensboro, North CarolinaAges 18–25 - NCT04781972RecruitingPhase 4
Brain scan study of ADHD effects from methylphenidate
This study uses brain imaging (MRI) to see how methylphenidate affects brain activity in people with ADHD. It may help doctors better understand how this medicine works and who benefits most.
Baltimore, MarylandAges 6–40 - NCT04750551Recruiting
Breathing stimulation to improve arm movement after stroke
This trial studies a breathing-related stimulation method (called BreEStim) to help improve arm and hand movement after stroke. It may help people who still have muscle stiffness in the hand and arm months after a stroke.
Houston, TexasAges 18–75 - NCT04699799Recruiting
Studies how the brain processes smells
This study looks at specific parts of the brain that help connect smells with emotion. You may be able to join if you’re an adult and there are no other limits on your health.
Chicago, IllinoisAges 18 years+ - NCT04578808Recruiting
Tracking unruptured brain aneurysms over three years
This study follows adults with a small, unruptured brain aneurysm to better predict how it may change over time. It may help doctors estimate which aneurysms are more likely to worsen and guide future care.
Marseille, Bouches-du-RhôneAges 18 years+ - NCT04348318Recruiting
Evaluating an advance care plan for ICU patients
This study looks at how well advance care planning documents are put into action for people who stay in the intensive care unit (ICU). If you participated, it may help the hospital improve how patients’ wishes are followed during serious illness.
AarauAges 18 years+ - NCT04317677Recruiting
See if bladder pee timing affects infant sleep
This study checks whether changing or timing bladder emptying (pee/voiding) affects how infants sleep. It may help families and clinicians understand sleep trouble in babies after a breathing/safety event, so care can be better targeted.
BronAges 1 month–1 year - NCT04270734Recruiting
Brain-wave study of hearing timing from babyhood to adulthood
This study looks at brain activity (brain waves) when babies hear sounds with timing, and how that changes with age. It may help researchers understand early brain development in hearing and processing sounds.
AmiensAges birth–1 day - NCT04094428Recruiting
Study of ICU outcomes, deaths, and care costs
This study looks at what happens to people in intensive care, including deaths and hospital resource use. It may help hospitals plan better care and understand the costs of staying in the ICU.
UlmAges Any age - NCT03965988RecruitingPhase 3
Omega-3 oil to help children’s breath-holding spells
This trial studies whether docosahexaenoic acid (an omega-3 fatty acid found in fish oil) can reduce breath-holding spells in children who have just been diagnosed. If it works, it could help lessen how often these spells happen and how severe they are.
TantaAges 1 month–5 years - NCT03807401Recruiting
Prismatic test study to support daily independence after brain injury
This study tests a new vision-related “prismatic adaptation” task to see if it could help people with daily independence after a brain injury. Because you’d be asked to do technical testing, the main goal is to understand how the test works in healthy people.
BronAges 18–70 - NCT03366506Recruiting
Study factors linked to ALS development
This study looks at people who might have amyotrophic lateral sclerosis (ALS) to understand what factors are associated with how the condition starts and develops. If you have a suspected or confirmed ALS diagnosis, it may help researchers learn what influences ALS and potentially guide future prevention or care.
JerusalemAges 12–120 - NCT02766166Recruiting
Study of health status scores in monitored hospital patients
This study looks at how a “health score” measures a patient’s condition and outcomes while they are in the hospital with heart monitoring. It may help doctors better assess risk and track how patients do over time.
Indianapolis, IndianaAges 18 years+ - NCT01434368Recruiting
How the brain and hormones change during puberty
This study follows healthy 8‑year‑olds over time to understand how hormones and brain development change during puberty. Participants will have MRI scans, X‑rays, and other tests to track normal growth.
Bethesda, MarylandAges 7–35 - NCT07161999RecruitingPhase 2/Phase 3
COYA 302 treatment for ALS
This study tests an experimental treatment called COYA 302 for ALS. It aims to see if it can slow down the worsening of muscle weakness and improve daily function. It might be an option for people in the earlier stages of ALS.
Phoenix, ArizonaAges 18–80 - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.