Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT07849413Recruiting
Visual hallucinations in Lewy body diseases
This study looks at why some people with Lewy body diseases (like Parkinson's or dementia with Lewy bodies) see things that aren't there. It uses brain scans and tests to learn more, which might help improve future care.
New York, New YorkAges 18–90 - NCT07850570Recruiting
Custom jaw plates for jaw fracture repair
This trial tests two types of custom-made plates used to fix broken jawbones. One is titanium (a strong metal) and the other is PEEK (a medical plastic). Both are shaped to fit your jaw. The goal is to help the bone heal properly after surgery.
Al Mansurah, Dakahlia GovernorateAges 18–50 - NCT07845032Recruiting
Online coping skills for dementia caregivers
This study tests an online program that teaches skills to help you cope with the stress of caring for someone with dementia or memory loss. It aims to see if becoming more flexible in your thinking can reduce your distress.
Logan, UtahAges 18 years+ - NCT07844590Recruiting
Early breathing problem detection in ALS
This study tests new ways to find breathing problems early in people with ALS. It uses MRI scans and other checks to see how the disease affects breathing muscles, which could help doctors treat symptoms sooner.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07846007Recruiting
Ultrasound brain stimulation for Parkinson's disease
This study tests a non-invasive ultrasound treatment that gently stimulates a small part of the brain to see if it can improve Parkinson's symptoms like movement and stiffness. It may be an option for people who have not had brain surgery yet.
Toronto, OntarioAges 18–90 - NCT07847424Recruiting
Daily heat therapy for people reducing physical activity
This study tests whether daily heat therapy (sauna sessions) can help maintain fitness and health when people temporarily reduce their physical activity. If you are a healthy adult, you might be able to join and contribute to understanding how heat affects the body.
Provo, UtahAges 18 years+ - NCT05780905RecruitingPhase 4
Semaglutide study for brain blood flow in type 2 diabetes
This trial tests whether semaglutide changes blood flow in the brain and the brain’s “barrier” (how well the brain is protected) in people with type 2 diabetes. It may help researchers understand brain-related effects of diabetes treatment using scans and blood tests.
Seattle, WashingtonAges 40–65 - NCT06443268Recruiting
Stroke and quality of life study with caregivers
This study looks at quality of life for people who have had a recent stroke or mini-stroke, and their caregivers. You and a close relative or friend both take part in interviews and surveys over time.
Zurich, Canton of ZurichAges 18 years+ - NCT06444776Recruiting
Taste and saliva changes during radiotherapy for head & neck cancer
This study looks at how radiation therapy for head and neck cancer changes your sense of taste and saliva. It aims to better understand and manage these side effects.
Aarau, Canton of AargauAges 18 years+ - NCT06383689Recruiting
Improving comfort during epilepsy monitoring
This study tests if changing how we give placebo pills during long hospital monitoring can make the experience better and less stressful for people with epilepsy. The goal is to improve care for those who need this test before epilepsy surgery.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
La Jolla, CaliforniaAges 21–75 - NCT06440070Recruiting
Ultrasound-guided needle thread release for carpal tunnel
This trial tests a new, less invasive way to release the tight ligament in the wrist that causes carpal tunnel syndrome. It uses ultrasound to guide a curved needle and thread to cut the ligament, which may lead to less pain and faster recovery.
Guangzhou, GuangdongAges 40–70 - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT05177055Recruiting
Sleep program for delayed sleep timing with mental health symptoms
This study offers a sleep-focused program to people whose sleep schedule is significantly shifted later than desired (delayed sleep phase disorder) along with moderate to severe mental health symptoms. It aims to see if treatment for the sleep problem can help in people already getting psychiatric care.
Bergen, TertnesAges 18–80 - NCT06451887Recruiting
Predicting brain swelling after stroke treatment
This study looks at how to predict dangerous brain swelling after endovascular treatment for large artery stroke. It uses CT scans to identify patients at risk, which could help doctors monitor and treat them more closely.
Hangzhou, ZhejiangAges 18–80 - NCT06451172RecruitingEarly Phase 1
New antibiotic eye drops for drug-resistant eye infections
This trial tests a new type of antibiotic eye drop for people with serious eye infections that don't respond to standard antibiotics. It aims to see if these drops can safely treat the infection and help improve vision.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT03610763Recruiting
Training brain recovery after arm nerve repair
This study tests a way to help your brain and nerves work better after an arm/hand nerve repair that is already in the long-term (chronic) recovery stage. It may help improve hand and arm function by targeting “neuroplasticity,” meaning the brain’s ability to adapt after injury.
Louisville, KentuckyAges 18 years+ - NCT04005508Recruiting
Study sleep apnea and heart outcomes in high-risk atrial fibrillation
This trial looks at how obstructive sleep apnea (OSA, a breathing problem during sleep) relates to heart outcomes in people with atrial fibrillation (AF). It may help doctors better predict risk and choose safer care for people who are high cardiovascular risk.
SingaporeAges 22–99 - NCT06455488Recruiting
Ventricular tachycardia management outcomes registry
This registry collects information about how ventricular tachycardia (a fast heart rhythm from the lower chambers) is managed and the results of different treatments. Participating can help improve future care.
Chicago, IllinoisAges 18 years+ - NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT06456684Recruiting
AV133 PET scan study in early Parkinson's disease
This study uses a special PET scan to look at a protein (VMAT2) in the brain that is linked to Parkinson's disease. It helps researchers understand early changes in people with newly diagnosed Parkinson's or those at high risk of developing it.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06374433Recruiting
How the brain learns: a brain stimulation study
This study explores how the brain learns and adapts (called brain plasticity) using a non-invasive brain stimulation technique. It may help understand learning and perception in healthy young adults.
MilanAges 18–35 - NCT06456814Recruiting
Study on how brain aneurysms form, grow, and rupture
This study looks at medical records from multiple hospitals in China to understand how brain aneurysms develop and when they might rupture. It may help researchers find better ways to predict and treat them.
GuangzhouAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.