Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,473 recruiting studies in this area right now.
By phase
- Not applicable9,815
- Phase 2785
- Phase 1573
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia152
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California674
- Massachusetts306
- New York293
- Florida277
- Texas270
- Maryland245
- Arizona213
- Alabama212
- Illinois193
- Pennsylvania177
Recruiting studies12,471 total
- NCT07086742Recruiting
Testing a smart mask that measures oxygen and pulse
This study tests a new 'smart mask' that can measure your oxygen levels and pulse rate. It is for healthy adults to see how well the mask works compared to standard devices.
GenkAges 18–65 - NCT07087002RecruitingPhase 1
GPC2-CAR T cells for children and young adults with relapsed medulloblastoma
This trial tests a new type of cell therapy called GPC2-CAR T cells for children and young adults whose medulloblastoma or related brain tumor has come back or not responded to standard treatment. The goal is to see if these specially designed immune cells can find and attack the tumor.
Palo Alto, CaliforniaAges 1–30 - NCT07087106RecruitingPhase 4
Glucose use in the brain of people with MS
This study uses a special PET scan to see how the brain uses sugar (glucose) in people with multiple sclerosis (MS) compared to healthy volunteers. It may help researchers understand energy changes in the brain related to MS.
Boston, MassachusettsAges 18–70 - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT07087743Recruiting
Virtual reality rehab for walking after stroke
This study uses virtual reality to help people who have had a stroke improve their walking. It provides feedback on how you push off with your feet, which may strengthen your walking pattern.
Galveston, TexasAges 20 years+ - NCT07087769Recruiting
Improving walking symmetry after stroke with special devices
This study uses special devices and feedback to help people who have had a stroke walk more evenly (symmetrically). It tests if these tools can improve walking patterns and balance.
Galveston, TexasAges 20 years+ - NCT07087821Recruiting
Epilepsy self-management study for depression
This study tests two programs (UPLIFT and PACES) that help people with epilepsy manage depressive symptoms. If you have epilepsy and mild-to-moderate depression, you may be able to join.
Brooklyn, New YorkAges 18 years+ - NCT07087912RecruitingPhase 4
Dengue vaccine safety in people with autoimmune rheumatic diseases
This study tests the safety and immune response of a dengue vaccine in people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are on low-dose or no immune-suppressing medications. It also includes healthy volunteers for comparison.
São Paulo, São PauloAges 12–59 - NCT07087873Recruiting
Testing brain stimulation for memory problems in inflammatory diseases
This trial tests if a gentle electrical current applied to the scalp can improve memory and thinking in people with certain inflammatory conditions that affect the brain and spinal cord.
Beijing, Beijing MunicipalityAges 18–60 - NCT07088107Recruiting
Brain training with TMS and fNIRS for arm recovery after stroke
This trial uses a brain-computer interface (TMS and fNIRS) to help people with chronic stroke regain arm function. It tests if combining brain stimulation with real-time brain activity feedback can improve movement.
Hong KongAges 18–80 - NCT07088250Recruiting
Statins for Treating Brain Bleeding
This trial tests if the statin drug atorvastatin can help people recover from a type of stroke called a brain bleed. It is for adults who have a moderate-sized bleed in the upper part of the brain and can start taking the drug within 48 hours of symptoms.
Anqing, AnhuiAges 18–80 - NCT07088835Recruiting
Safety study of ear-worn seizure monitor
This study tests a new ear-worn sensor to monitor brain activity. It will see if the device is safe and easy to use for recording seizures. Healthy volunteers and people with suspected seizures are both needed.
New York, New YorkAges 18–70 - NCT07089095Recruiting
Choosing rehab after a stroke: your preferences matter
This study looks at what matters to you when choosing rehabilitation care after a recent stroke. By joining, you can help doctors understand how to better support people like you in recovery.
TaipeiAges 18 years+ - NCT07089303Recruiting
Alzheimer's brain imaging study (AD-MINER)
This study uses advanced brain imaging to learn more about Alzheimer's disease. It looks at people with normal memory, mild memory problems, or Alzheimer's dementia to find better ways to diagnose and track the disease.
Beijing, Beijing MunicipalityAges 55–90 - NCT07089797Recruiting
Sleep app support for cancer caregivers
This trial tests a mobile app with nurse support to help cancer caregivers manage their sleep. The app uses cognitive behavioral therapy for insomnia (CBT-I) to teach skills for better sleep.
ShanghaiAges 18 years+ - NCT07090057Recruiting
Targeting the plantaris muscle in ankle surgery for children
This study tests if removing the plantaris muscle during surgery improves ankle movement in children with tight heel cords. It aims to see if this extra step leads to better outcomes.
Edmonton, AlbertaAges 4–17 - NCT07090200Recruiting
Rehabilitation program for COPD with heart or blood vessel disease
This study tests a rehabilitation program for people with COPD who also have heart or blood vessel problems. It aims to help you breathe better and improve your overall health.
Wuhan, HubeiAges 18 years+ - NCT07090356Recruiting
Soft tissue therapy versus stretching for athletes with piriformis syndrome
This study compares two techniques—instrument-assisted soft tissue mobilization and PNF stretching—to see which works better for reducing pain and improving movement in athletes with piriformis syndrome. It may help if you are an athlete with ongoing buttock or hip pain that makes sitting uncomfortable.
Lahore, Punjab ProvinceAges 18–35 - NCT07090395Recruiting
Expanding use of EVO oral appliance for severe sleep apnea
This trial tests whether an EVO oral appliance can treat severe obstructive sleep apnea in people who haven't used other treatments recently. It aims to see if the device works for a wider group of patients.
New York, New YorkAges 18–80 - NCT07090551Recruiting
Mouthguard for jaw and neck muscle pain from grinding
This study tests whether a custom mouthguard (occlusal splint) can reduce pain and tension in the jaw and neck muscles. It is for people with bruxism (teeth grinding) and myofascial pain, a type of muscle pain in the jaw area.
IstanbulAges 18–50 - NCT07090733Recruiting
Nerve blocks for shoulder surgery: comparing breathing and pain relief
This study compares three different nerve blocks to see which one causes less breathing trouble and provides better pain relief after arthroscopic shoulder surgery. It may help patients who are having shoulder surgery and want to avoid side effects like muscle weakness.
Tanta, El-GharbiaAges 21–65 - NCT07091045Recruiting
Robot-Assisted Foot-Ankle Training for Stroke Recovery
This trial tests a robot-assisted training program for the foot and ankle in people who have had a stroke at least 6 months ago. The goal is to improve movement and walking by using special exercises guided by a robotic device.
Istanbul, IstanbulAges 40–65 - NCT07091149Recruiting
Digital insomnia treatment for children ages 6–12
This study tests a digital cognitive behavioral therapy program (NiteCAPP Jr) for children ages 6–12 who have insomnia. It aims to see if the program is feasible, acceptable, and helpful for improving sleep and daytime function.
Tampa, FloridaAges 6–12 - NCT07091318RecruitingEarly Phase 1
CBT for insomnia in type 1 diabetes
This study tests whether cognitive behavioral therapy for insomnia (CBTi) can improve sleep in people with type 1 diabetes. It may help those who have poor sleep quality and use a continuous glucose monitor.
Chicago, IllinoisAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,473 recruiting neurology studies from the U.S. registry right now, out of 19,792 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.