Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT05615610Recruiting
Electrical stimulation therapy for brain and arm recovery after stroke
This trial tests whether painless electrical nerve stimulation placed on the skin can improve thinking (cognitive function) and arm movement in people living with long-term stroke. If you qualify, you may receive this non-drug therapy and be assessed for changes in memory/thinking and upper-limb movement.
Hong KongAges 50–80 - NCT05332249Recruiting
Registry for Degenerative Spine Disease in the Neck and Low Back
This study is a registry (a way to collect health information) for people with wear-and-tear (“degenerative”) problems in the neck and/or low back. It may help doctors better understand these conditions and improve future care plans.
Seoul, KoreaAges 18–100 - NCT05556655Recruiting
Brain stimulation and how it changes memory task performance
This study tests how a brain stimulation method affects how well you do thinking and memory tasks. You would complete cognitive testing before and after the stimulation, and the researchers look at whether your performance changes.
Fort Collins, ColoradoAges 18–65 - NCT05613686Recruiting
Brain stimulation after stroke to help arm movement
This trial tests a non-painful brain stimulation therapy to improve arm movement after a stroke. It may help people recover motor function when starting within a few months and meeting safety and participation requirements.
TaipeiAges 20 years+ - NCT05606068Recruiting
Cooling sleeve to help prevent nerve damage from paclitaxel
This trial tests a limb “cryocompression” system (a cooling and gentle pressure device) to help prevent chemotherapy-related nerve pain and numbness. It’s for people starting weekly paclitaxel, and may help those trying to avoid or reduce peripheral neuropathy.
SingaporeAges 21–80 - NCT05283174Recruiting
Blood thinner use during stroke to predict outcomes
This study looks at how people doing well on certain blood thinners do when they have a stroke or bleeding while taking them. It will measure medication levels in your blood to understand stroke severity and recovery in the short and long term.
TaipeiAges 20 years+ - NCT05578560Recruiting
Virtual reality rehab after vestibular schwannoma surgery
This trial studies whether virtual reality (VR) exercises can help people recover movement and balance after surgery for a vestibular schwannoma. If you’re eligible, you may be asked to use VR as part of your rehabilitation program.
PragueAges 18 years+ - NCT05502718Recruiting
Exercise program for cervical dystonia treated with botulinum toxin
This trial studies whether a structured exercise program can help people with cervical dystonia (involuntary neck muscle tightening) who are already being treated with botulinum toxin type A. It may help improve how you move and function, alongside your usual injections.
Ankara, AltındağAges 18 years+ - NCT07228754Recruiting
Stroke caregiver expectations study
This study looks at how realistic caregivers' expectations are for people recovering from a stroke, within the first 6 months. It may help understand what caregivers need to know to better support their loved one.
Ankara, YenimahalleAges 18–75 - NCT05328401Recruiting
Laser acupuncture for shoulder pain after stroke
This trial tests whether laser acupuncture can reduce shoulder pain in people recovering from a stroke. It compares outcomes while making sure participants are not using certain pain medicines or shoulder injections that could affect results.
Keelung, TaiwanAges 20 years+ - NCT05152823Enrolling by invitationPhase 1/Phase 2
Gene therapy for IGHMBP2-related nerve conditions
This early-phase study tests a gene therapy meant to treat people who have IGHMBP2 gene changes. It aims to improve the way the nervous system works and to see if the treatment is safe, especially in young children.
Columbus, OhioAges 2 months–14 years - NCT04831242Recruiting
Monitoring newborn health in intensive care
This study checks how a newborn’s body changes over time in an intensive care unit, using routine monitoring. Your child may benefit by being closely observed, and the results may help improve care for future newborns.
CambridgeAges Any age - NCT04936646Recruiting
Brain stimulation study for long-term nerve pain
This trial tests whether a form of brain stimulation (rTMS) can reduce chronic nerve pain that has lasted more than a year and hasn’t improved with standard treatments. It may help people whose usual pain medicines are stable but still not working well.
Grenoble, IsèreAges 18–80 - NCT05102916Recruiting
Registry for neuromuscular disorder patients in Switzerland
This study is a patient registry that collects health information from people diagnosed with a neuromuscular disorder in Switzerland. It helps researchers better understand these conditions and how they vary from person to person.
Aarau, Canton of AargauAges birth+ - NCT04916652Recruiting
Study brain flexibility in Chinese toddlers using special scans
This study uses MRI brain scans to look at how “neural flexibility” develops in typically developing toddlers. It compares toddlers who drink a specific formula gum or regular cow’s milk to understand how diet may relate to brain development.
Shanghai, Shanghai MunicipalityAges 2.7 years–2.8 years - NCT05191121Enrolling by invitation
Rehab program to improve arm and trunk control after spinal injury
This trial helps people with recent traumatic spinal cord injury improve arm movement and trunk (upper body) stability using a training program that includes electrical stimulation. If you’re early after injury and can safely use stimulation, you may benefit from more controlled movement for daily tasks.
Englewood, ColoradoAges 18 years+ - NCT05192759Recruiting
Theta-burst brain stimulation for walking freezing in Parkinson’s
This trial tests whether a specific type of noninvasive brain stimulation (theta-burst TMS) can improve “freezing of gait,” where walking suddenly stops. It may help by targeting brain circuits involved in movement, especially if your symptoms persist despite stable medication.
Hefei, AnhuiAges 40–85 - NCT05124964Recruiting
Quality of life study for newly diagnosed brain germ cell tumors
This study looks at how life quality changes in children and young adults after a new diagnosis of a brain germ cell tumor. It may help doctors understand which supports improve day-to-day well-being.
BeijingAges 3–30 - NCT05203965RecruitingEarly Phase 1
Brain imaging study testing mavoglurant in alcohol risk
This early-stage study uses brain scans to understand how brain signaling tied to alcohol vulnerability works, and it tests mavoglurant, a medicine that blocks a brain receptor. Results may help researchers learn why some people are more vulnerable to alcohol problems.
Hartford, ConnecticutAges 18–45 - NCT05194254Recruiting
MRI eye-tracking study for social thinking in autistic children
This study uses MRI to measure how children’s eyes track during tasks, aiming to better understand social thinking in autism. It includes both autistic participants and children with very low autism scores to compare results.
Amiens, PicardieAges 10–20 - NCT04914585Recruiting
3D CT scan test to automatically identify spine bones
This study checks whether a computer can automatically spot and label the bones in your spine using 3D information from a CT scan. It may help surgeons work faster and more accurately before spine surgery.
JerusalemAges 18 years+ - NCT04750564Recruiting
BreEStim to help arm movement after long-term stroke
This pilot study tests a type of nerve stimulation (BreEStim) to improve arm and finger movement in people with chronic stroke-related stiffness. It may help if you have persistent, measurable muscle tightness and are medically stable.
Houston, TexasAges 18–75 - NCT05091112Recruiting
Study of nerves during low back surgery
This study looks at tiny nerves in the low back during planned lumbar spine surgery. It may help researchers better understand nerve pathways that contribute to low back pain and nerve-related symptoms.
Aberdeen, ScotlandAges 18 years+ - NCT04737889RecruitingPhase 2
Rituximab plus lenalidomide, methotrexate, and temozolomide for brain lymphoma
This Phase 2 study tests a combination treatment to shrink primary central nervous system lymphoma that starts in the brain, spinal cord, meninges, or eye. It may help patients who have not had anti-cancer treatment yet, but it requires specific cancer type and health conditions.
Zhengzhou, HenanAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.