Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT06679790Recruiting
Understanding changes in Tourette Syndrome over time
This study tracks how tics and related symptoms change over time in people with Tourette Syndrome. It aims to better understand the condition and could help develop better treatments.
Minneapolis, MinnesotaAges 12–17 - NCT06677502Enrolling by invitation
Cerebrolysin for delirium in ICU patients
This trial tests a medicine called Cerebrolysin to see if it helps reduce confusion and agitation (delirium) in patients who are critically ill and being treated in the ICU. It may be an option for you if you are over 18 and have delirium symptoms.
Lubin, Lublin VoivodeshipAges 18–100 - NCT06677216Enrolling by invitation
Botox for jaw muscle pain study
This study tests if Botox injections can reduce pain in the jaw muscles caused by a jaw joint disorder (TMD). If you have this type of pain and are interested in Botox treatment, you may be able to join.
Utrecht, UtrechtAges 18 years+ - NCT06676501Enrolling by invitation
Second side focused ultrasound for essential tremor
This study tests whether a second focused ultrasound treatment on the other side of the brain can safely and effectively reduce tremor in people with essential tremor who already had one treatment. It's for those whose tremor is not well controlled by medication or previous treatments.
BeijingAges 22 years+ - NCT06674603Enrolling by invitation
Cognitive recovery after ICU delirium
This study follows patients who experienced delirium in the ICU to track how their thinking and memory recover over time, and what factors might help or hinder that recovery.
Guiyang, GuizhouAges 18 years+ - NCT06671626Enrolling by invitation
Brain recordings during DBS surgery for Parkinson's
This study records brain activity during deep brain stimulation (DBS) surgery for Parkinson's disease to better understand how the brain controls actions. It might help improve future treatments.
Dallas, TexasAges 18 years+ - NCT06658223Enrolling by invitation
Virtual reality for fibromyalgia pain
This trial tests if using immersive virtual reality can help reduce pain and improve well-being in people with fibromyalgia. If you have fibromyalgia and are over 18, you may be able to join.
Concepción, BiobioAges 18 years+ - NCT06656637Enrolling by invitation
Do memory drills help veterans remember things?
This study tests if doing short memory drills can help veterans with brain injuries or PTSD improve their ability to remember to do tasks. You'll practice on a tablet or computer and see if your memory gets better.
Los Angeles, CaliforniaAges 18 years+ - NCT06649799Enrolling by invitation
Comparing two lasers for cataract surgery in older adults
This study tests two different femtosecond lasers (LenSx and Z8) used during cataract surgery to see how they affect the eye's natural response, including inflammation and pupil size. It is designed for adults over 50 with age-related cataracts of moderate hardness.
Hangzhou, ZhejiangAges 50–80 - NCT06649461Enrolling by invitation
Ozone therapy and splint for carpal tunnel syndrome
This trial tests if adding ozone therapy to a wrist splint helps relieve mild-to-moderate carpal tunnel syndrome symptoms like numbness, tingling, and pain. It compares the combination to a splint alone.
KocaeliAges 18–65 - NCT06649084Enrolling by invitation
Language treatment study for primary progressive aphasia
This study tests a multi-component language treatment for people with primary progressive aphasia (a type of dementia that first affects language). It aims to help improve communication skills with support from a study partner.
Austin, TexasAges Any age - NCT06643858Enrolling by invitation
Normal Chinese Lifespan Brain Chart Study
This study creates a 'normal brain map' by taking MRI scans of healthy people of all ages. It helps doctors understand what a healthy brain looks like at different stages of life.
Beijing, Beijing MunicipalityAges 6–90 - NCT06642519Enrolling by invitation
Brain-computer interface for freezing of gait in Parkinson's
This study tests a brain-computer interface device to help people with Parkinson's disease who experience freezing of gait. The goal is to see if the device can reduce freezing episodes when medication isn't enough.
Toronto, OntarioAges Any age - NCT06642454Enrolling by invitation
Breathing-guided nerve stimulation for Parkinson's disease
This study tests a type of nerve stimulation (vagus nerve) for Parkinson's disease. It compares a method that uses your breathing cycle to deliver stimulation versus standard stimulation. The goal is to see which works better for movement and non-movement symptoms.
Hefei, AnhuiAges 40–80 - NCT06641193Enrolling by invitation
rTMS for arm slowness in early Parkinson's
This trial tests a brain stimulation technique called rTMS to see if it can help improve slowness of movement in the arm and hand. It's for people with early-stage Parkinson's whose symptoms started on the left side and whose main problem is moving slowly.
Shanghai, ChinaAges 50–75 - NCT06635174Enrolling by invitation
Sugar water for pain relief before infant catheter
This study tests if giving a small amount of sugar water (50% dextrose) by mouth can help reduce pain in babies who need a bladder catheter. It might be a gentler way to comfort infants during this procedure.
Muscat, Muḩāfaz̧at MasqaţAges 1 day–3 months - NCT06634004Enrolling by invitation
Using biomarkers to improve surgery outcomes in Moyamoya
This study at Vanderbilt tests whether certain biomarkers (signs in your blood or brain scans) can help tailor care for people with Moyamoya, a condition where blood flow to the brain is reduced. Participants will have brain scans and complete study procedures before and after surgery to improve blood flow.
Baltimore, MarylandAges 18–69 - NCT06633263Enrolling by invitation
Combined therapy for depression and insomnia
This trial tests a combination of two behavioral therapies to improve both depression symptoms and sleep problems. It may help you if you have moderate depression and insomnia and can participate in French-language sessions.
LiègeAges 18–67 - NCT06631807Enrolling by invitation
How blindness affects sleep, dreams, and spatial skills
This study looks at how the number of years a person has been blind affects their sleep, dreams, and spatial abilities. It may help us understand how the brain adapts when vision is lost, which could lead to better support for people with visual impairments.
GenovaAges 18–85 - NCT06627543Enrolling by invitation
Enzyme replacement therapy for heart health in Gaucher type 3
This study looks at how enzyme replacement therapy affects heart function in children with Gaucher disease type 3. It aims to see if the therapy helps keep the heart healthy.
AsyutAges Any age - NCT06625294Enrolling by invitation
Hand therapy after stroke: comparing two approaches
This study compares two types of hand therapy for stroke survivors: one that restricts your good hand to force use of the affected hand, and another that practices tasks with both hands together. The goal is to see which works better for improving hand function.
IslamabadAges 40–60 - NCT06623149Enrolling by invitation
Surgery vs. non-surgery for knee arthritis
This study compares non-surgical treatments with knee replacement surgery for people with knee osteoarthritis. It aims to find out which approach works better.
Copenhagen, CopenhagenAges Any age - NCT06622473Enrolling by invitation
Testing the virtual eggs test for stroke recovery
This trial tests a virtual task called the 'Eggs Test' to see if it can help measure hand and arm function after a stroke. It may help people who are at least 2 weeks past their first stroke and can move their arm enough to do the task.
Florence, FlorenceAges 18–85 - NCT06618157Enrolling by invitation
Brain stimulation study for Parkinson's tremor
This study tests a new way to adjust deep brain stimulation (DBS) for Parkinson's disease. It focuses on people who still have at least mild tremor after their DBS device has been in place for three months or more, to see if targeting specific brain connections can help improve tremor control.
Durham, North CarolinaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.