Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT06223074Enrolling by invitationPhase 2
Nasal Steroid Spray for MS Relapses
This study tests a nasal spray form of the steroid methylprednisolone for treating MS relapses. The goal is to see if this new way of taking the medicine works as well or better than standard treatments.
Mexico CityAges 18–65 - NCT06215105Enrolling by invitation
Collecting real-world data on treatments for brain aneurysms
This trial is gathering information from patients who are getting a standard treatment for a brain aneurysm using MicroVention devices. It helps doctors understand how well these treatments work in real life.
Hollywood, FloridaAges Any age - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT06185816RecruitingPhase 2/Phase 3
Non-invasive pulsed radiofrequency for nerve pain
This trial tests a non-invasive treatment called pulsed radiofrequency for people with chronic nerve pain after an injury. It uses a device that sends short bursts of energy to the painful area to help reduce pain without surgery.
Redwood City, CaliforniaAges 18 years+ - NCT06178627Enrolling by invitationPhase 4
Amphotericin B for non-HIV cryptococcal meningitis
This trial tests the drug amphotericin B for people with cryptococcal meningitis who do not have HIV. The goal is to see if this treatment is safe and effective.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06167642Enrolling by invitation
Retinal health and nerve markers in MS patients taking ofatumumab
This study looks at how ofatumumab (Kesimpta) affects the back of the eye (retina) and certain nerve proteins in the blood in people with relapsing multiple sclerosis. It may help doctors understand how well the medication is protecting the eyes and nerves.
Baltimore, MarylandAges 18–70 - NCT06164756Enrolling by invitation
Long-term follow-up of the ketamine for Parkinson's trial
This study follows up on people with Parkinson's disease who took part in an earlier trial testing the effects of ketamine. It looks at how they do over a longer period of time.
New Haven, ConnecticutAges 40–80 - NCT06163508Enrolling by invitation
Long-term follow-up for Q-Cells recipients
This study is for people who have already received Q-Cells treatment. It does not test new treatments; instead, it checks on your health over a long time to see how you are doing.
Dallas, TexasAges Any age - NCT06148311Enrolling by invitationPhase 2
Dexmedetomidine film for autonomic crises in Familial Dysautonomia
This study tests a new dissolvable film containing dexmedetomidine (a medicine that calms overactive stress responses) for people with Familial Dysautonomia who experience sudden episodes called autonomic crises. It aims to treat these crises at home without needing a hospital visit.
New York, New YorkAges 16–80 - NCT06145555Enrolling by invitation
Sleep stabilization therapy for hospitalized depression
This study tests a quick, non-drug sleep therapy for people in the hospital for depression. It aims to help stabilize your sleep to improve your mood and recovery.
StockholmAges 18 years+ - NCT06144957Enrolling by invitation
SLC13A5 deficiency natural history study (US only)
This study follows people with SLC13A5 deficiency (a rare genetic condition that affects brain development) to learn more about the disease over time. It collects health information, assessments, and samples to help understand the condition and plan future treatments.
Palo Alto, CaliforniaAges Any age - NCT06138808Enrolling by invitation
5-sense score validation for epilepsy surgery
This study is for people with epilepsy who are being considered for brain surgery but cannot have a direct surgical approach. It tests a new scoring method (5-SENSE) that uses non-invasive tests like MRI and EEG to see if it can help doctors make better surgery decisions.
Gainesville, FloridaAges 15 years+ - NCT06121492Enrolling by invitationPhase 3
Amino Acid Drink for Muscle Loss in Liver Cirrhosis
This study tests whether taking a daily drink of branched-chain amino acids (a type of protein) can help people with liver cirrhosis who have lost muscle strength and mass. It may help improve muscle size and function.
Bangkok, BangkokAges 18–85 - NCT06117332Enrolling by invitation
AI-Enhanced Vision for People with Visual Implants
This study tests a new AI system designed to improve what people with visual prostheses 'see.' If you have an implanted device like the Argus II or Orion, you may be able to help by coming to the lab for several days of vision testing.
Santa Barbara, CaliforniaAges 18 years+ - NCT06115291Enrolling by invitation
Smell training study for adults with smell loss
This study tests whether a daily smell training routine can help improve your sense of smell. It is open to adults with any kind of smell loss or problem, including those with conditions like COVID-19 or head injury, but not certain brain diseases.
Kansas City, KansasAges 18–80 - NCT06108102Enrolling by invitation
Post-stroke epilepsy research database study
This trial is creating a global research database to learn more about seizures that happen after a stroke. By joining, you help doctors better understand who gets these seizures and how to treat them.
New Haven, ConnecticutAges 18 years+ - NCT06105307Enrolling by invitation
Improving sleep and fatigue for night shift RNs
This trial uses mobile technology and cognitive-behavioral techniques to help night shift nurses improve their sleep and reduce fatigue. If you work night shifts and have a smartphone, you may be eligible to join.
Cincinnati, OhioAges 18 years+ - NCT06104397Enrolling by invitation
Exercise strategies for Parkinson's disease
This study compares different exercise plans to see which works best for people with Parkinson's. You will use an activity tracker and a phone app to track your progress.
Chicago, IllinoisAges 18–89 - NCT06101940Enrolling by invitation
Chinese study tracking myotonic dystrophy type 1 outcomes
This study follows people with myotonic dystrophy type 1 (DM1) over time to learn more about how the disease progresses. It collects health information and samples to help improve care.
Beijing, Beijing MunicipalityAges Any age - NCT06100926Enrolling by invitation
Virtual reality for chronic muscle pain
This study tests whether virtual reality (VR) can help reduce chronic muscle pain that is not caused by cancer. If you have fibromyalgia or similar long-lasting muscle pain, you may be able to join.
Udine, Friuli Venezia GiuliaAges 18–50 - NCT06097013Enrolling by invitation
Brain function study for consciousness disorders
This trial is testing a brain function evaluation system to help understand and possibly improve care for people with disorders of consciousness caused by brain injury, stroke, or lack of oxygen. It is for both acute (recent) and prolonged (lasting) cases.
BeijingAges 14–60 - NCT06096831Enrolling by invitation
Living with stroke: studying healthcare use over time
This study looks at how stroke survivors use healthcare services over time. It hopes to find ways to improve long-term support and care after a stroke.
HaifaAges 18 years+ - NCT06095284Enrolling by invitation
Antiseizure drug use in nursing homes before and after COVID-19
This study looks at how antiseizure medications are prescribed to long-term nursing home residents and how those prescriptions changed during the COVID-19 pandemic. It helps understand if prescribing patterns affected residents' health.
Richmond, VirginiaAges 21 years+ - NCT06084533Enrolling by invitation
Brain inflammation imaging in Parkinson's disease
This study uses a special PET scan to look for signs of brain inflammation in people with Parkinson's disease. It aims to understand how inflammation relates to Parkinson's and may help in developing new treatments.
St Louis, MissouriAges 50 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.