Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT06347432Enrolling by invitation
Study to help kids with severe cerebral palsy gain independence
This trial tests a power wheelchair training system for children with severe cerebral palsy who cannot walk or use a manual wheelchair. It aims to help them move more independently using switches or a joystick.
Grand Rapids, MichiganAges 5–17 - NCT06344026Enrolling by invitationPhase 1
A cell therapy trial for Parkinson's disease
This trial tests a new treatment made from your own cells to replace damaged brain cells, aiming to improve movement and reduce symptoms. It's for people who have had Parkinson's for at least 4 years and respond well to levodopa.
Tucson, ArizonaAges 40–75 - NCT06341829Enrolling by invitation
Vision and emotions in Parkinson's disease
This study explores how Parkinson's disease affects visual and emotional abilities. It aims to understand these challenges better to improve future care.
Messina, MessinaAges 18–90 - NCT06336525Enrolling by invitation
Sleep health in rural Appalachia and Mississippi Delta
This study examines how sleep is linked to heart and metabolic health in people living in rural Appalachia and the Mississippi Delta. If you are already part of the RURAL Study, you may be able to join this sleep-focused part of the research.
Boston, MassachusettsAges 25–65 - NCT06330324Enrolling by invitation
Reproductive choices for genetic skin conditions
This study looks at the choices families have when they carry a genetic skin condition. It aims to learn more about how prenatal testing and IVF with genetic testing can help.
Maastricht, LimburgAges Any age - NCT06330116Enrolling by invitation
Mouth and throat exercises for snoring and mild sleep apnea
This study tests different forms of oral myofunctional therapy (exercises for your mouth and throat) to find out which works best for reducing snoring and mild to moderate sleep apnea. It may help you breathe better and sleep more soundly.
Köge, Region SjællandAges 18–75 - NCT06326177Enrolling by invitation
Spine, shoulder, and core study for competitive swimmers
This study looks at how the spine, shoulders, and core muscles work together in swimmers. It may help understand how to prevent injuries and improve performance.
Istanbul, KadıköyAges 12–24 - NCT06320782Enrolling by invitation
Diet and belly fat study for overweight adults
This study tests how different diets affect belly fat, thigh muscle, and heart health in people who are overweight. It might help you find a way to eat that improves your health.
Recife, PernambucoAges 20 years+ - NCT06312189Enrolling by invitationPhase 3
Long-term safety study of valbenazine for Huntington's chorea in Canada
This study is for people in Canada who have already been taking valbenazine for Huntington's chorea in a previous study (NBI-98854-HD3006). It tests the long-term safety of the medicine and continues for up to 156 weeks.
Vancouver, British ColumbiaAges 18 years+ - NCT06311877Enrolling by invitation
Berry flavor for taste changes during radiation
This study tests if a berry-flavored product can help manage taste changes caused by radiation therapy for mouth or throat cancer. It may improve your quality of life during treatment.
Tampa, FloridaAges 18–90 - NCT06306157Enrolling by invitationPhase 4
Low dose naltrexone for complex regional pain syndrome
This trial tests whether a low dose of naltrexone, a medication that may help calm overactive immune and pain signals, can reduce pain and improve daily life in people with complex regional pain syndrome (CRPS), a chronic condition that often causes severe pain and swelling.
New York, New YorkAges 18–85 - NCT06305039Enrolling by invitation
Better hearing with two cochlear implants
This study tests how well people with two cochlear implants (or one cochlear implant and one hearing ear) can hear in complex, noisy settings. It aims to improve how these devices help in everyday listening situations.
Bethesda, MarylandAges 18–85 - NCT06300502Enrolling by invitationPhase 1
Monthly injections for NF1 skin bumps
This study tests if a monthly injection of deoxycholate can shrink or reduce the number of visible skin bumps (cutaneous neurofibromas) in people with NF1. It is designed for adults with at least 6 bumps that can be treated and monitored.
Boston, MassachusettsAges 18–85 - NCT06285448Enrolling by invitation
Lecanemab registry and outcome study
This study looks at how well lecanemab (a new Alzheimer's treatment) works in real-world clinics. It also tracks how patients and their care partners do over time. If you are already getting or eligible for lecanemab, you might join with your care partner.
Saint Paul, MinnesotaAges 18 years+ - NCT06270719Enrolling by invitation
Comparing ELEVIDYS to standard care for Duchenne muscular dystrophy
This study compares the gene therapy ELEVIDYS (delandistrogene moxeparvovec) to usual treatments for people with Duchenne muscular dystrophy (DMD). It helps researchers understand how well ELEVIDYS works over time in real-world settings.
Little Rock, ArkansasAges 4 years+ - NCT06270251Recruiting
Modeling tic changes during behavior therapy
This study looks at how tics change during a type of behavior therapy for tics. It may help teens and young adults better understand what happens during treatment.
Minneapolis, MinnesotaAges 12–21 - NCT06267222Enrolling by invitation
Spinal electrical stimulation for spinocerebellar ataxia
This study tests a noninvasive electrical stimulation therapy applied to the spine to see if it can improve movement and coordination in people with spinocerebellar ataxia. It may help with walking and balance.
Rio de Janeiro, Rio de JaneiroAges 18–70 - NCT06261528Enrolling by invitationPhase 1
Light therapy for sleepiness in progressive MS
This trial tests whether a special light therapy can help people with progressive multiple sclerosis who feel sleepy during the day. It aims to improve energy, mood, and sleep patterns.
Dallas, TexasAges 18 years+ - NCT06257420Enrolling by invitation
Low-dose rapamycin for ME/CFS and Long-COVID
This trial tests whether a low dose of rapamycin, a drug that may help regulate the immune system, can improve symptoms in people with ME/CFS or Long-COVID.
Palo Alto, CaliforniaAges 18–65 - NCT06252532Enrolling by invitation
Brain wave study for epilepsy with electrodes
This research study looks at how certain brain waves (called theta oscillations) help you focus and prioritize information. If you have epilepsy that hasn't been controlled with medicines and you already have brain electrodes in place for your epilepsy monitoring, you may be able to join this study to help scientists understand the role of these brain signals.
Chapel Hill, North CarolinaAges 18–80 - NCT06251817Enrolling by invitation
Wideband ear sound test in Thai adults
This study measures how sound travels through the ear in Thai adults with normal hearing or conductive hearing loss. The results will help doctors better understand ear function and improve diagnosis.
Khon KaenAges 18–59 - NCT06247904Enrolling by invitation
Brain stimulation for arm paralysis after spinal cord injury
This study tests a noninvasive brain stimulation method (NIBS) to help people with recent spinal cord injuries regain arm and hand function. It is designed for patients who have some paralysis in their arms but still have some movement or sensation below their injury level.
Elkins Park, PennsylvaniaAges 18–80 - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT06225388Enrolling by invitation
Do compression socks help runners feel less sore?
This study tests whether wearing a compression sock while running can reduce muscle soreness after a run. It may help distance runners recover faster.
Rio de JaneiroAges 18–50
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.