Oncology
Cancer clinical trials
Studies of cancers and tumors of every type and site, from prevention to treatment. We’re tracking 20,651 recruiting studies in this area right now.
By phase
- Not applicable9,821
- Phase 24,456
- Phase 12,741
- Phase 1/Phase 21,690
- Phase 31,400
- Phase 2/Phase 3281
- Phase 4262
Top conditions
- Breast Cancer1,231
- Cancer660
- Prostate Cancer655
- Colorectal Cancer493
- Lung Cancer426
- Ovarian Cancer340
- Multiple Myeloma330
- Gastric Cancer300
- Pancreatic Cancer294
- Acute Myeloid Leukemia293
- Hepatocellular Carcinoma284
- Solid Tumor258
- Advanced Solid Tumor257
- Cervical Cancer231
- Head and Neck Cancer227
- Endometrial Cancer205
- Advanced Solid Tumors195
- Esophageal Cancer193
Leading sponsors
- M.D. Anderson Cancer Center452
- Fudan University314
- Sun Yat-sen University291
- Memorial Sloan Kettering Cancer Center289
- National Cancer Institute (NCI)286
- Mayo Clinic239
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences151
- City of Hope Medical Center144
- AstraZeneca133
- University Health Network, Toronto125
Where studies are running
- California1,426
- Texas641
- Arizona511
- Florida449
- Alabama419
- New York411
- Massachusetts339
- Maryland329
- New Jersey268
- Pennsylvania240
Recruiting studies20,651 total
- NCT04973306RecruitingPhase 2/Phase 3
Chemo-immunotherapy before surgery versus chemo-radiation
This trial compares adding immunotherapy to standard chemo-radiation before surgery for locally advanced, operable esophageal squamous cell cancer. It aims to improve how well the tumor responds and whether patients do better after surgery.
ShanghaiAges 18–75 - NCT04973293Recruiting
Pre-surgery immunotherapy plus chemo and blood-vessel medicine for lung cancer
This study tests whether giving sintilimab (an immune therapy) combined with bevacizumab (a blood-vessel–targeting medicine) plus chemotherapy before surgery can improve outcomes for resectable lung cancer. It’s meant for people with specific lung cancer types and good health for surgery, and it avoids certain cancer types and immune-related risks.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04974671RecruitingPhase 2
SBRT radiation for limited cancer growth on immunotherapy
This trial tests whether targeted external-beam radiation (SBRT) can control a small number of progressing kidney cancer spots while you continue immune checkpoint inhibitor immunotherapy. It may help shrink or stop those specific “oligoprogressive” lesions and prolong benefit from your current immunotherapy.
New Haven, ConnecticutAges 18 years+ - NCT04974866RecruitingPhase 2
Targeted pills for advanced adenoid cystic cancer that keeps growing
This Phase 2 trial studies targeted “tyrosine kinase inhibitor” pills for adenoid cystic carcinoma that has spread or cannot be cured with surgery or radiation and is growing despite prior treatment. It’s looking for whether these pills can shrink tumors or slow progression and is mainly for adults with measurable disease on recent scans.
Qingdao, ShandongAges 18–90 - NCT04975152RecruitingPhase 1
Cemiplimab before surgery for Merkel cell and skin cancers
This early-phase study tests cemiplimab (an immune therapy that helps your immune system attack cancer) given before surgery. It aims to shrink tumors and improve outcomes for people with Merkel cell cancer or certain locally advanced skin squamous cell cancers (CSCC).
Tampa, FloridaAges 18 years+ - NCT04976296Recruiting
Monitoring minimal residual disease after lung cancer surgery
This study checks whether a special blood/tissue test called MRD (minimal residual disease, meaning tiny leftover cancer signals) can help monitor lung cancer after surgery. It may help doctors spot relapse earlier after your tumor has been fully removed.
Guangzhou, GuangdongAges 18 years+ - NCT04977180RecruitingPhase 2
Beta blocker and lisinopril to protect the heart in AML
This Phase 2 study tests whether a blood-pressure medicine plan (a beta blocker plus lisinopril) can protect the heart in people newly diagnosed with acute myeloid leukemia (AML) who are starting anthracycline chemotherapy. It looks at heart safety by requiring a good heart scan before treatment and careful medication eligibility.
Charlottesville, VirginiaAges 18 years+ - NCT04977375RecruitingPhase 1/Phase 2
Anti–PD-1 treatment plus focused radiation for recurrent glioblastoma
This trial tests a cancer-immunotherapy medicine (an anti–PD-1 antibody, similar to pembrolizumab) combined with precisely targeted radiation to treat glioblastoma that has come back or progressed. It may help your immune system recognize and attack the tumor while the radiation targets the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT04977791Recruiting
Study how drug resistance develops in lung cancer immunotherapy
This study looks at lung tumor tissue and blood to understand why immune checkpoint drugs can stop working in non-small cell lung cancer. It may help researchers find better ways to predict and overcome drug resistance.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04979078Recruiting
Light therapy to ease chemotherapy hand-foot skin reaction
This study tests whether a light-based therapy (photobiomodulation) can reduce pain and skin irritation from hand-foot syndrome/hand-foot skin reaction in people getting chemotherapy or targeted medicines. It may help you heal sooner and feel more comfortable while treatment continues.
Hasselt, LimburgAges 18 years+ - NCT04979156Recruiting
Laser removal of bladder tumors in one piece
This trial studies using a specific laser technique to remove bladder tumors “en bloc” (in one piece) during a procedure. It may help reduce leftover tumor tissue and improve how safely the tumor can be removed for people with certain small, papillary bladder tumors.
Kansas City, KansasAges 18 years+ - NCT04980716RecruitingPhase 3
Heart-based early intervention for stage III lung cancer using heart signals
This trial tests an early heart-focused intervention guided by a special heart recording (impedance cardiography) in people with locally advanced, unresectable stage III non-small cell lung cancer. The goal is to improve heart-related safety during planned radiation and chemotherapy, with or without immunotherapy.
Guangzhou, GuangdongAges 18–75 - NCT04980287Recruiting
Surgery trial for colon cancer spread to stomach-area fat
This trial studies whether a specific surgery that removes the colon’s associated tissue (and part of the nearby stomach-area tissue) improves outcomes for certain colon cancer cases that are at risk of spreading there. If you qualify, your doctors will compare your treatment approach as part of the study to see if it helps.
Wuhan, HubeiAges 18–75 - NCT04982744Recruiting
Li-Fraumeni and related syndrome patient registry
This is a research registry that collects information from people who have Li-Fraumeni or similar inherited cancer syndromes. It helps doctors better understand these conditions and improve future care.
Bologna, Emilia-RomagnaAges Any age - NCT04981119Recruiting
Test apheresis for CAR T manufacturing in HLA-A2 solid tumors
This trial studies how a process called apheresis is used to make CAR T cells for people with certain solid tumors. It is designed for tumors that have lost a specific immune marker (HLA-A*02), which may affect how well CAR T therapies work.
Gilbert, ArizonaAges 18 years+ - NCT04981509RecruitingPhase 2
Check if 3 medicines help advanced kidney cancer
This Phase 2 trial tests whether combining bevacizumab, erlotinib, and atezolizumab can shrink or control advanced kidney cancer. It’s aimed at people with certain kidney-cancer subtypes (including HLRCC-related cases or papillary kidney cancer) and who have not had many prior targeted or immune treatments.
La Jolla, CaliforniaAges 12 years+ - NCT04982653RecruitingPhase 2
Stitch type study to prevent hernia after liver surgery
This trial compares two ways of closing the belly incision after open liver surgery to see which best lowers the chance of getting an incisional hernia (a bulge near the scar). It may help by guiding surgeons toward the closure method that prevents hernias better.
Houston, TexasAges 18 years+ - NCT04983121RecruitingPhase 2
Neoadjuvant pyrotinib plus ARX788 for HER2-positive breast cancer
This Phase 2 trial studies whether combining pyrotinib with ARX788 given before surgery can work better and be safe in people with HER2-positive breast cancer. It’s designed for tumors that did not respond well enough to earlier trastuzumab and pertuzumab treatment.
Shenyang, LiaoningAges 18–75 - NCT04983199Recruiting
Tablet and app program during palliative radiation for cancer pain
This study checks whether a mobile app and wearable sensor can help collect patient-reported outcomes during palliative radiation for cancer pain. It may help researchers better understand symptoms and pain control from the patient’s perspective.
Toronto, OntarioAges 18 years+ - NCT04985032Recruiting
Radiation after lumpectomy for selected breast tumors
This trial tests a shorter, focused type of radiation (APBI using SBRT) after lumpectomy for certain early breast cancers. It may help by targeting only the part of the breast where the tumor was, rather than treating the whole breast, while keeping safety and cancer control in mind.
Stuart, FloridaAges 50–100 - NCT04984551RecruitingPhase 2
Training plus support to improve palliative care for advanced cancer
This trial studies whether a program called Project ECHO can improve the quality of palliative care (comfort-focused care) for people with advanced cancer and their caregivers in underserved areas. It also involves training local health care providers so they can better support patients and families over time.
Houston, TexasAges Any age - NCT04986293Recruiting
CPAP or BiPAP to reduce motion during radiation
This study tests whether using a breathing machine (CPAP or BiPAP) can help keep you still during radiation treatment. This may improve how accurately radiation is delivered for certain cancers treated with curative intent.
Groningen, Provincie GroningenAges 18 years+ - NCT04985058Recruiting
Study of abemaciclib plus hormone therapy in breast cancer
This study uses real-world health records to learn about outcomes in people with hormone-receptor positive, HER2-negative breast cancer who were treated with abemaciclib along with hormone (endocrine) therapy. It may help doctors better understand how well this treatment works outside of clinical trials.
AthensAges 18 years+ - NCT04986657Recruiting
Whole genome testing to help diagnose AML or MDS
This study checks whether adding whole genome sequencing (reading a person’s DNA more broadly) alongside standard genetic tests improves the diagnosis process for AML or MDS. It may help doctors decide on the best next steps when AML/MDS is suspected.
St Louis, MissouriAges 18 years+
Common questions
- How many cancer clinical trials are recruiting?
- Clin2 is tracking 20,651 recruiting oncology studies from the U.S. registry right now, out of 31,668 we cover in this area in total.
- What does “Cancer” cover here?
- Studies of cancers and tumors of every type and site, from prevention to treatment. We group each study into cancer based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a cancer trial near me?
- Use the search to filter cancer studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.