Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,599 recruiting studies in this area right now.
By phase
- Not applicable4,683
- Phase 21,187
- Phase 1568
- Phase 3457
- Phase 1/Phase 2366
- Phase 4228
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer478
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Colon Cancer114
- Hepatocellular Carcinoma (HCC)112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- Chinese University of Hong Kong55
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona189
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,599 total
- NCT06869694Recruiting
Energy ct scan for stomach cancer diagnosis
This study uses a special type of ct scan (energy ct) to help doctors see stomach cancer more clearly. If you have been diagnosed with stomach cancer and are scheduled for surgery, this imaging test may help guide your treatment.
Zhengzhou, ChinaAges 18 years+ - NCT06868875Recruiting
Small bowel MRI data sharing study
This study asks permission to use past MRI scans of your small bowel for research. It aims to improve how we understand and diagnose bowel conditions.
LondonAges 16 years+ - NCT07315893Recruiting
Closing stomach defects with a stitching device
This trial tests a special stitching tool to close holes in the stomach after removing abnormal growths. It may help patients heal better after a routine procedure to remove suspicious tissue.
Tel AvivAges 18 years+ - NCT07315854RecruitingPhase 2
Immunotherapy combo plus chemo for untreated stomach cancer
This trial tests a new combination of two immunotherapy drugs (iparomlimab and tuvonralimab) plus chemotherapy for people with advanced stomach or gastroesophageal junction cancer who have not had prior treatment. It aims to see if this combination can shrink tumors and help people live longer.
Beijing, Beijing MunicipalityAges 18–80 - NCT07319442Recruiting
German registry for inflammatory bowel disease
This is a long-term registry study that follows people with chronic inflammatory bowel diseases to better understand the conditions and improve care. By joining, you help researchers learn more about how these diseases affect patients over time.
HamburgAges 18 years+ - NCT07319078Recruiting
Online treatment for kids with stomach pain
This study tests an internet-based program to help children and teens with certain long-term stomach conditions, like irritable bowel syndrome (IBS) or ongoing stomach pain. It aims to see if online tools can reduce symptoms and improve daily life.
StockholmAges 8–17 - NCT07322848RecruitingPhase 3
Comparing two TACE methods for liver cancer patients with TIPS
This trial tests whether a newer targeted chemotherapy bead method (DEB-TACE) works better than standard chemo beads (cTACE) for people with liver cancer who already have a TIPS shunt in place. It aims to find a treatment that controls tumors while being safe for patients with this shunt.
Guangzhou, GuangdongAges 18–75 - NCT07317193Recruiting
Genetic causes of adult bile duct disease
This study looks for new genes that might cause abnormal liver test results or specific bile duct diseases in adults, when standard testing hasn't found a clear cause. It also uses healthy blood donors as a comparison group.
Milan, MilanoAges 18–65 - NCT07322627Recruiting
Esophageal cancer genetics and treatment outlook study
This study looks at a specific gene (ALDH2) in people with esophageal cancer to see if it affects how well they respond to treatment. It may help doctors better predict outcomes and personalize care.
TaipeiAges 18–99 - NCT07317011Recruiting
Active referral for hepatitis B patients
This trial aims to connect adults with chronic hepatitis B to proper care. It tests an active referral program for patients hospitalized in specific departments in Bergamo, Italy, or attending certain clinics, to see if it improves follow-up and treatment.
BergamoAges 18–100 - NCT07324785Recruiting
Link between sugar substances and stomach problems in diabetes
This study looks at how sugar-related substances (called advanced glycation end products) might affect stomach muscle function in people with diabetes who have gastroparesis (slow stomach emptying). It compares them to people without diabetes to better understand the link.
Yangzhou, JiangsuAges 18–75 - NCT07318389RecruitingEarly Phase 1
Tracking tumor resistance in metastatic colorectal cancer
This trial studies how colorectal cancer that has spread becomes resistant to treatment. By taking biopsies over time, researchers hope to find new ways to target the cancer and help patients live longer.
Houston, TexasAges 18 years+ - NCT07317414RecruitingPhase 2
Beta-alanine for advanced liver cancer
This trial tests whether beta-alanine, a natural supplement, can help people with advanced liver cancer that cannot be removed by surgery. It aims to see if the treatment can slow tumor growth and improve outcomes.
Beijing, Beijing MunicipalityAges 18–75 - NCT07317609RecruitingPhase 1
Immunotherapy plus chemo before endoscopic resection for esophageal cancer
This trial tests a treatment plan that combines immunotherapy with chemotherapy before possible endoscopic surgery. It is for people with a specific type of esophageal cancer that has not been treated before and is either potentially removable or not suitable for standard surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07324824RecruitingPhase 2
Sintilimab plus bevacizumab before surgery for liver cancer
This trial tests two drugs, sintilimab and bevacizumab, given before surgery to treat liver cancer that can be removed. It's for people with a certain stage of liver cancer who haven't had other treatments.
Guangzhou, GuangdongAges 18 years+ - NCT07316621Recruiting
Crohn's disease risk study for close relatives
This study follows close family members of people with Crohn's disease to see if they develop early signs of the condition. It uses blood tests and checkups to detect Crohn's earlier.
RomaAges 16–35 - NCT07321431Recruiting
Finding the best time to check gallbladder function
This study is looking for people with healthy gallbladders and bile ducts to find the best time to measure how well the gallbladder works. It uses a simple ultrasound test and does not involve any drugs or procedures.
Lanzhou, GansuAges 18–70 - NCT07320586RecruitingPhase 2
Carilizumab and chemo for advanced gastric cancer
This trial tests a combination of carilizumab (an immunotherapy) and albumin paclitaxel (a chemotherapy drug) for people with advanced stomach or gastroesophageal junction cancer that has gotten worse after first-line treatment. It aims to see if this second-line option can help control the cancer.
Jinan, ShandongAges 18–75 - NCT07317687Recruiting
Rapid HIV, Hep C, and Syphilis Testing in Street Medicine
This trial offers free rapid testing for HIV, hepatitis C, and syphilis during street medicine visits. It helps find infections early so you can get connected to care.
Harpers Ferry, West VirginiaAges 18 years+ - NCT07324096Recruiting
Screening for pancreatic cancer in people with new diabetes
This study screens people with recent diabetes who are at high risk for pancreatic cancer. It uses a CT scan to find cancer early, when it may be easier to treat.
Rochester, MinnesotaAges 50–85 - NCT07323407Recruiting
Brain stimulation for hard-to-treat constipation with bodily distress
This trial tests if a gentle electrical current applied to the scalp can improve severe constipation in people who also experience persistent physical symptoms (like pain or bloating) that cause high worry. It is for those who have not gotten relief from standard laxatives.
Xi'an, ShaanxiAges 18–80 - NCT07322978Recruiting
Blood Clots in Veins of the Gut During Pancreatitis
This study looks at how often blood clots form in veins near the gut (called splanchnic venous thrombosis) in people with acute pancreatitis. It also checks if the clots are linked to how severe the pancreatitis is. The goal is to help doctors better understand and possibly prevent these clots.
Hyderabad, TelanganaAges 18–85 - NCT07317492Recruiting
Hemorrhoids and varicose veins study
This study looks at the connection between hemorrhoids and varicose veins. It may help researchers understand if these conditions are related and how to better treat them.
Aydin, EfelerAges 18 years+ - NCT07319364RecruitingPhase 1
Fecal transplant study for cancer treatment side effects
This trial tests whether fecal transplants (putting healthy donor bacteria into your gut) can help with side effects like diarrhea, constipation, or nausea caused by cancer treatments. It is for people with advanced gastrointestinal cancer who are about to start their fourth round of chemo or targeted therapy.
Zhejiang, HangzhouAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,599 recruiting gastroenterology studies from the U.S. registry right now, out of 11,991 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.