Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,606 recruiting studies in this area right now.
By phase
- Not applicable4,686
- Phase 21,188
- Phase 1568
- Phase 3457
- Phase 1/Phase 2368
- Phase 4229
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer479
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Hepatocellular Carcinoma (HCC)114
- Colon Cancer112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Chinese University of Hong Kong56
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona190
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,606 total
- NCT07122622Recruiting
Spleen stiffness test to check for dangerous veins in the liver
This trial uses a non-invasive ultrasound test to measure spleen stiffness, which may help find problems with blood pressure in the liver and identify enlarged veins that can bleed. It could help avoid more invasive tests.
Roma, ItaliaAges 18 years+ - NCT07124858Recruiting
Fruquintinib for advanced colorectal cancer
This study tracks how well fruquintinib works for people with advanced colorectal cancer that has spread. It aims to find factors that predict better outcomes, using blood and tumor samples.
Poitiers, FranceAges 18 years+ - NCT07122219Recruiting
Needle exchange access in federal prisons
This study looks at whether making needle and syringe programs easier to use helps more people in prison get clean needles. It's about reducing infection risks for everyone at the participating prisons.
Edmonton, AlbertaAges 18 years+ - NCT07120295RecruitingPhase 4
Study of a new scope for bile duct problems
This trial tests a special scope that helps doctors see inside the bile duct during an ERCP procedure. It may help people with blocked bile ducts that can't be treated with standard methods.
Aurora, ColoradoAges 21 years+ - NCT07125729Recruiting
Early cancer detection test for colorectal cancer
This trial uses two blood tests (Signatera and Haystack) to look for tiny bits of cancer DNA after surgery, to find out if the cancer comes back as early as possible. People with stage II, III, or IV colorectal cancer who have had or will have surgery to remove their tumor may join.
Goodyear, ArizonaAges 18 years+ - NCT07117032RecruitingPhase 1
Radiation therapy for cancer-related stomach pain
This trial tests a type of radiation therapy (SBRT) to treat severe stomach pain caused by cancer pressing on nerves near the stomach. It aims to provide pain relief without the need for a standard nerve block procedure.
Cleveland, OhioAges 18 years+ - NCT07125625Recruiting
Probiotic mixture for children with irritable bowel syndrome
This study tests whether a mixture of two friendly bacteria (probiotics) can improve belly pain and other IBS symptoms in children. If your child qualifies, they may receive the probiotic mixture or a placebo for a period of time.
Bari, BariAges 4–18 - NCT07117045Recruiting
Low-dose CT scan for pancreatic cancer screening
This study uses artificial intelligence to analyze low-dose CT scans of the abdomen to detect early signs of pancreatic cancer. It may help find cancer before symptoms appear.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07122700Recruiting
Better tests for fatty liver disease in people with metabolic issues
This study compares new, non-invasive tests to standard liver biopsy for diagnosing fatty liver disease in people with type 2 diabetes or other signs of metabolic syndrome. It aims to see if these simpler tests can replace biopsies.
Miami, FloridaAges 18–75 - NCT07122024RecruitingPhase 4
Testing a dual therapy for H. pylori treatment
This trial tests a two-drug treatment (keverprazan and amoxicillin) for people who have H. pylori and have not been treated for it before. The goal is to see if this newer combination works well and is safe.
Hangzhou, ZhejiangAges 18–65 - NCT07124611Recruiting
Emotional support study for pancreatic cancer patients
This study offers a brief psychological intervention to help patients with pancreatic cancer manage emotional well-being before surgery. It is designed for newly diagnosed patients who are starting chemotherapy before surgery.
Columbus, OhioAges 18 years+ - NCT07119463RecruitingPhase 2
Albumin infusion to reduce complications after gastric cancer surgery
This trial tests whether giving albumin (a protein in the blood) during and after surgery can help prevent complications in people with stomach cancer. It is for those who have surgery to remove their tumor and have normal or near-normal blood albumin levels before surgery.
Changchun, JilinAges 18–80 - NCT07122089RecruitingPhase 2
SIRT plus immunotherapy for liver cancer with portal vein clot
This trial tests a two-step approach for liver cancer that has spread into the portal vein. First, you receive internal radiation (SIRT) to shrink the tumor, followed by immunotherapy drugs (durvalumab with or without tremelimumab) to help your immune system fight the cancer. The goal is to see if this combination is safe and effective.
GrenobleAges 18 years+ - NCT07116486RecruitingPhase 1
Using a new PET scan to guide liver cancer treatment
This trial tests a special PET scan (18F-FSPG) to help guide therapy for people with liver cancer (HCC) who are planning to receive Y90 radioembolization. The scan may help doctors better plan your treatment.
Houston, TexasAges 18 years+ - NCT07118657Recruiting
Vegan diet's effect on gut health in kids with autoimmune hepatitis
This study looks at how a vegan diet changes the bacteria in the gut and how that affects diet and disease in children with autoimmune hepatitis. Healthy children are included as a comparison group.
New Delhi, National Capital Territory of DelhiAges birth–18 years - NCT07125521Recruiting
Smartphone app study for GERD medication adherence
This study tests whether using a smartphone app called GERDCare helps people with GERD take their medications as prescribed. It may be a good fit if you have typical GERD symptoms like heartburn or regurgitation and are comfortable using a smartphone app.
HanoiAges 18 years+ - NCT07117318Recruiting
NSAIDs with or without a pancreatic stent to prevent pancreatitis after ERCP
This trial tests whether using rectal NSAIDs (a type of painkiller) with or without a small tube (stent) in the pancreas can prevent pancreatitis after ERCP. It's for people who are at higher risk for this complication.
Beijing, Beijing MunicipalityAges 18–90 - NCT07119346Recruiting
Nerve block for pain after feeding tube surgery in children
This trial tests whether a nerve block (EOI) given before surgery can reduce pain after a feeding tube procedure in children. It aims to help kids recover more comfortably.
SeoulAges 3–17 - NCT07116564RecruitingPhase 4
Enhanced recovery after laparoscopic gynecological surgery
This study tests whether a special set of recovery steps (called an ERAS protocol) can help you leave the hospital sooner after your laparoscopic gynecological surgery. If you qualify, you'll receive this enhanced recovery plan instead of standard care.
Karachi, SindhAges 20–60 - NCT07115862Recruiting
Pomegranate juice study for mild to moderate ulcerative colitis
This trial tests if drinking pomegranate juice can help people with mild to moderate ulcerative colitis. You may be eligible if your diet is low in fruits and vegetables and you are on stable medications.
Los Angeles, CaliforniaAges 18 years+ - NCT07124351RecruitingPhase 4
Using a special dye to see cancer during surgery
This trial tests a drug called pafolacianine (CYTALUX) that makes cancer cells glow during surgery. It may help doctors see and remove more cancer from the stomach, esophagus, or appendix. You take the drug before surgery, and a special camera shows the glowing cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT07124754Recruiting
Predicting lymph node spread in early stomach cancer
This study tests if artificial intelligence can predict whether early-stage stomach cancer has spread to lymph nodes. It also evaluates how well doctors assess the cancer. If the technology works, it could help guide treatment decisions.
Shijiazhuang, None SelectedAges 18 years+ - NCT07125001Recruiting
Mango study for Hispanic/Latino teens' health
This study looks at whether eating mango every day for 12 weeks can improve gut health and heart health in Hispanic/Latino teens who are overweight. Participants will be asked to eat a mango product and take daily photos.
Davis, CaliforniaAges 12–19 - NCT06935994RecruitingPhase 2
Aspirin for Fatty Liver Disease (MASLD)
This study tests whether aspirin can help people with MASLD, a type of fatty liver disease linked to conditions like diabetes and obesity. It aims to see if aspirin can improve liver health without causing harm.
Taichung, TaiwanAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,606 recruiting gastroenterology studies from the U.S. registry right now, out of 12,023 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.