Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,896 recruiting studies in this area right now.
By phase
- Not applicable4,922
- Phase 21,186
- Phase 1581
- Phase 3466
- Phase 1/Phase 2394
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer492
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer100
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University90
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida134
- Massachusetts128
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,896 total
- NCT06796114Recruiting
Biomarkers in advanced liver cancer treated with tremelimumab/durvalumab
This study is looking for people with advanced liver cancer (hepatocellular carcinoma) who have not yet had systemic treatment. Participants will receive a combination of two immunotherapy drugs: tremelimumab and durvalumab (the STRIDE regimen). The goal is to find biomarkers that can predict how well the cancer responds to this treatment.
BesançonAges 18 years+ - NCT06797193Recruiting
Ultrasound technique to find liver blood pressure
This trial tests a new ultrasound technique called SHAPE to see if it can detect high blood pressure in the liver (portal hypertension) without needing an invasive procedure. It may help people who are already scheduled for a standard liver pressure measurement.
Scottsdale, ArizonaAges 18 years+ - NCT06797206Recruiting
CF in pregnancy and child health study
This study follows women with cystic fibrosis (CF) during pregnancy and after birth, and checks on their babies and young children. The goal is to learn more about how CF affects pregnancy and child development.
LondonAges Any age - NCT06798155Recruiting
Music to prevent pain after anal surgery
This study tests whether listening to a specific set of music before and after surgery for hemorrhoids, fistula, or anal fissure can help reduce pain. You would use a phone or tablet app to listen to short music sessions.
Saint-DenisAges 18 years+ - NCT06798545Recruiting
Study of a new navigation system for pancreas EUS
This trial is testing a new navigation system to help doctors see the pancreas during an endoscopic ultrasound (EUS) exam. The system may make it easier to spot lesions or other problems in the pancreas.
StrasbourgAges 18 years+ - NCT06799637RecruitingPhase 1/Phase 2
Study of XNW28012 for advanced solid tumors
This trial tests a new drug called XNW28012 for people with advanced solid tumors that have not responded to or caused side effects from standard treatments. It aims to see if the drug can shrink tumors or slow their growth.
Hefei, AnhuiAges 18 years+ - NCT06799793Recruiting
AI screening for early colorectal cancer detection
This study uses an artificial intelligence model to analyze test results from the fecal immunochemical test (FIT) to help find colon cancer early. You may benefit if you are 50-69 and had a positive FIT result as part of a screening program.
Bologna, BolognaAges 50–69 - NCT06800326Recruiting
Comparing MRI and ultrasound for Crohn's treatment response
This trial compares two types of scans—MRI and ultrasound—to see how well they detect changes in Crohn's disease after treatment. If you've had one of these scans already and need another to check your response to therapy, you may be able to join.
LondonAges 16–99 - NCT06800469Recruiting
Gut bacteria study in pancreatic cancer surgery patients
This trial looks at gut bacteria in people having surgery for pancreatic cancer. It aims to understand how these bacteria might affect recovery or treatment outcomes.
Bologna, BOAges 18 years+ - NCT06800807Recruiting
Beliefs about thinking in teens with eating disorders
This study looks at how teens with eating disorders think about their own thoughts (called metacognition). It compares their responses to a group of teens without eating disorders to better understand the role of certain beliefs in these conditions.
Oggebbio, VerbaniaAges 12–17 - NCT06800911Recruiting
Metacognitive beliefs in obesity
This study explores how thinking patterns and beliefs about one's own thoughts may be linked to obesity. It aims to understand the role of metacognition in people with severe obesity.
Oggebbio, VerbaniaAges 18–65 - NCT06801067RecruitingPhase 1
Testing SER-155 for immunotherapy-related diarrhea
This trial tests an investigational oral medication (SER-155) for people whose diarrhea is caused by immunotherapy. It aims to calm the gut and reduce symptoms without needing stronger drugs.
Basking Ridge, New JerseyAges 18 years+ - NCT06801899Recruiting
Total vs. partial Whipple for high-risk pancreatic cancer
This trial compares removing the entire pancreas (total pancreatectomy) versus removing only the head (standard Whipple) for certain cancers of the pancreas, bile duct, or ampulla. It is for people whose surgeon thinks the pancreas connection after surgery is likely to leak, which can cause serious complications.
MünsterAges 18 years+ - NCT06802731Recruiting
Testing a tool to measure liver inflammation in NAFLD
This trial studies a device called LivQ-box to see if it can accurately measure liver inflammation in people with nonalcoholic fatty liver disease (NAFLD). It compares the device's results to a liver biopsy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06802887Recruiting
Long-term study of ustekinumab for Crohn's and colitis
This study follows patients with Crohn's disease or ulcerative colitis who started taking ustekinumab between February 2019 and March 2021, to see how well it works over time.
Bologna, BolognaAges 18 years+ - NCT06802991Recruiting
Optimized post-discharge care for older colon cancer patients
This trial tests better nutrition and follow-up care for older patients after colon cancer surgery. It focuses on people who are somewhat frail and at risk for poor nutrition, to see if extra support at home can improve recovery.
HerlevAges 65 years+ - NCT06803147Recruiting
Stopping Surveillance for Low-Risk Barrett's Esophagus
This study is testing whether it's safe to stop regular surveillance endoscopies for people with low-risk Barrett's esophagus. If you have a short Barrett's segment without any dysplasia, you may be able to avoid future procedures.
AmsterdamAges Any age - NCT06803108Recruiting
Pyramidal vs continuous exercise for fatty liver
This study compares two exercise programs to see which works better for people with fatty liver disease and obesity. It may help improve liver health through different workout styles.
GizaAges 37–51 - NCT06803368Recruiting
Recovery and maintenance strategies for chronic hepatitis B
This trial is for people with chronic hepatitis B who have already cleared the virus with interferon treatment. It tests ongoing strategies to help maintain their health and prevent the virus from coming back.
Beijing, Beijing MunicipalityAges 18–65 - NCT06803550Recruiting
Recovery program after anal surgery
This trial tests a special recovery program after surgery for common non-cancerous anal conditions like hemorrhoids, anal fissures, or fistulas. The goal is to see if this approach helps you heal faster and feel better.
Al MansurahAges 18–65 - NCT06803589RecruitingEarly Phase 1
Growth hormone for hard-to-treat stomach paralysis
This study tests if growth hormone can help people with long-term stomach paralysis (gastroparesis) that hasn't improved with standard care. It looks at whether the treatment reduces symptoms like nausea and feeling full too quickly.
Phoenix, ArizonaAges 18–65 - NCT06803771Recruiting
Pancreatic health monitoring after diabetes diagnosis
This study follows people newly diagnosed with type 2 diabetes to check their pancreas health using blood tests and MRI scans. It aims to find any early signs of pancreatic disease.
Sandbach, CheshireAges 50–84 - NCT06803927Recruiting
Detecting Barrett's esophagus with a non-endoscopic device
This trial tests a device that collects cells from the esophagus using a swallowed capsule, which may detect Barrett's esophagus without a standard endoscopy. It is for people who are already scheduled for an endoscopy.
Cordova, TennesseeAges 18 years+ - NCT06804733Recruiting
Personalized exercise for inflammatory bowel disease
This study tests whether a personalized aerobic exercise program (like walking or cycling) can help people with mild or inactive Crohn's disease or ulcerative colitis feel better. It lasts 12 weeks and is designed for people who don't currently exercise regularly.
Ningbo, ZhejiangAges 18–65
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,896 recruiting gastroenterology studies from the U.S. registry right now, out of 12,425 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.