Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,903 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,187
- Phase 1582
- Phase 3466
- Phase 1/Phase 2395
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,903 total
- NCT07114627Recruiting
Capecitabine and oxaliplatin study for cancer patients
This study looks at how your genes affect the way your body handles the chemotherapy drug capecitabine when it's taken with oxaliplatin. The goal is to understand if certain genetic differences can impact drug levels, which may help personalize treatment in the future.
RotterdamAges 18 years+ - NCT07114315RecruitingPhase 2
Study of AK130 plus AK112 for advanced pancreatic cancer
This trial tests a combination of two investigational drugs, AK130 and AK112, for people with advanced pancreatic cancer. It may be an option if you have had 1 or 2 prior treatments and are still relatively healthy.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07114939RecruitingPhase 1
A new pet scan for pancreatic neuroendocrine tumors
This study is testing a special type of PET/CT scan using a tracer called FTT to see if it can better find and track pancreatic neuroendocrine tumors that have spread or cannot be removed by surgery. The goal is to improve imaging for people with this type of cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07115043RecruitingPhase 1/Phase 2
Study of AZD6750 for advanced solid tumors
This trial tests a new drug called AZD6750 for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and effective.
Grand Rapids, MichiganAges 18 years+ - NCT07115303Recruiting
Comparing clips vs. sutures for appendix stump closure
This trial compares two ways to close the stump of the appendix during laparoscopic (minimally invasive) appendix removal: using clips versus tying a knot. The goal is to see which method works better and is safer for patients with simple appendicitis.
SohagAges Any age - NCT07115862Recruiting
Pomegranate juice study for mild to moderate ulcerative colitis
This trial tests if drinking pomegranate juice can help people with mild to moderate ulcerative colitis. You may be eligible if your diet is low in fruits and vegetables and you are on stable medications.
Los Angeles, CaliforniaAges 18 years+ - NCT07116096Recruiting
Handgrip strength and blood flow in liver cirrhosis
This study measures how handgrip strength relates to blood flow in the portal vein (the main vein to the liver) in people with liver cirrhosis. It aims to find simple ways to check liver health.
Luoyang, HenanAges 18 years+ - NCT07116486RecruitingPhase 1
Using a new PET scan to guide liver cancer treatment
This trial tests a special PET scan (18F-FSPG) to help guide therapy for people with liver cancer (HCC) who are planning to receive Y90 radioembolization. The scan may help doctors better plan your treatment.
Houston, TexasAges 18 years+ - NCT07117032RecruitingPhase 1
Radiation therapy for cancer-related stomach pain
This trial tests a type of radiation therapy (SBRT) to treat severe stomach pain caused by cancer pressing on nerves near the stomach. It aims to provide pain relief without the need for a standard nerve block procedure.
Cleveland, OhioAges 18 years+ - NCT07117045Recruiting
Low-dose CT scan for pancreatic cancer screening
This study uses artificial intelligence to analyze low-dose CT scans of the abdomen to detect early signs of pancreatic cancer. It may help find cancer before symptoms appear.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07118657Recruiting
Vegan diet's effect on gut health in kids with autoimmune hepatitis
This study looks at how a vegan diet changes the bacteria in the gut and how that affects diet and disease in children with autoimmune hepatitis. Healthy children are included as a comparison group.
New Delhi, National Capital Territory of DelhiAges birth–18 years - NCT07119203Recruiting
Robot vs standard keyhole gallbladder surgery for non-cancerous disease
This trial is comparing two types of keyhole surgery for removing the gallbladder: one done with a robot and the other with standard laparoscopic tools. The goal is to find out which technique leads to a better recovery and fewer complications for people with non-cancerous gallbladder problems like gallstones or polyps.
PortsmouthAges 18 years+ - NCT07119463RecruitingPhase 2
Albumin infusion to reduce complications after gastric cancer surgery
This trial tests whether giving albumin (a protein in the blood) during and after surgery can help prevent complications in people with stomach cancer. It is for those who have surgery to remove their tumor and have normal or near-normal blood albumin levels before surgery.
Changchun, JilinAges 18–80 - NCT07119957Recruiting
Liver cancer study: chemical and social risk factors
This study looks at how chemicals in our environment and life stress might be linked to liver cancer. It is for people with fatty liver disease caused by metabolism or alcohol, who are having a liver biopsy.
AngersAges 18 years+ - NCT07120295RecruitingPhase 4
Study of a new scope for bile duct problems
This trial tests a special scope that helps doctors see inside the bile duct during an ERCP procedure. It may help people with blocked bile ducts that can't be treated with standard methods.
Aurora, ColoradoAges 21 years+ - NCT07121803Recruiting
Special ice cream for esophagus health in diabetes
This study tests whether a special ice cream can help the esophagus (the tube that carries food to your stomach) work better in people with type 2 diabetes. Researchers want to see if the ice cream can improve how food moves down the esophagus.
MoscowAges 18–80 - NCT07122089RecruitingPhase 2
SIRT plus immunotherapy for liver cancer with portal vein clot
This trial tests a two-step approach for liver cancer that has spread into the portal vein. First, you receive internal radiation (SIRT) to shrink the tumor, followed by immunotherapy drugs (durvalumab with or without tremelimumab) to help your immune system fight the cancer. The goal is to see if this combination is safe and effective.
GrenobleAges 18 years+ - NCT07122219Recruiting
Needle exchange access in federal prisons
This study looks at whether making needle and syringe programs easier to use helps more people in prison get clean needles. It's about reducing infection risks for everyone at the participating prisons.
Edmonton, AlbertaAges 18 years+ - NCT07122622Recruiting
Spleen stiffness test to check for dangerous veins in the liver
This trial uses a non-invasive ultrasound test to measure spleen stiffness, which may help find problems with blood pressure in the liver and identify enlarged veins that can bleed. It could help avoid more invasive tests.
Roma, ItaliaAges 18 years+ - NCT07122700Recruiting
Better tests for fatty liver disease in people with metabolic issues
This study compares new, non-invasive tests to standard liver biopsy for diagnosing fatty liver disease in people with type 2 diabetes or other signs of metabolic syndrome. It aims to see if these simpler tests can replace biopsies.
Miami, FloridaAges 18–75 - NCT07124351RecruitingPhase 4
Using a special dye to see cancer during surgery
This trial tests a drug called pafolacianine (CYTALUX) that makes cancer cells glow during surgery. It may help doctors see and remove more cancer from the stomach, esophagus, or appendix. You take the drug before surgery, and a special camera shows the glowing cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT07124611Recruiting
Emotional support study for pancreatic cancer patients
This study offers a brief psychological intervention to help patients with pancreatic cancer manage emotional well-being before surgery. It is designed for newly diagnosed patients who are starting chemotherapy before surgery.
Columbus, OhioAges 18 years+ - NCT07124858Recruiting
Fruquintinib for advanced colorectal cancer
This study tracks how well fruquintinib works for people with advanced colorectal cancer that has spread. It aims to find factors that predict better outcomes, using blood and tumor samples.
Poitiers, FranceAges 18 years+ - NCT07125521Recruiting
Smartphone app study for GERD medication adherence
This study tests whether using a smartphone app called GERDCare helps people with GERD take their medications as prescribed. It may be a good fit if you have typical GERD symptoms like heartburn or regurgitation and are comfortable using a smartphone app.
HanoiAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,903 recruiting gastroenterology studies from the U.S. registry right now, out of 12,451 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.