Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,903 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,187
- Phase 1582
- Phase 3466
- Phase 1/Phase 2395
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,903 total
- NCT07150624RecruitingPhase 4
Polyene phosphatidylcholine for liver injury after surgery
This trial tests whether a medicine called polyene phosphatidylcholine can help protect the liver from damage after surgery for liver cancer. It is for people who are having a specific type of keyhole surgery to remove part of the liver.
Hefei, AnhuiAges 18–70 - NCT07151040RecruitingPhase 1/Phase 2
Testing TH9619 for advanced solid tumors
This trial tests a new drug called TH9619 for people with advanced cancers of the colon, head and neck, lung, or stomach. It aims to see if the drug is safe and works against tumors that have already been treated with chemotherapy.
VillejuifAges 18 years+ - NCT07151118Recruiting
Blood test for advanced biliary tract cancer
This study uses a simple blood test (ctDNA) to learn more about the genetic makeup of advanced biliary tract cancers. It may help researchers understand how these cancers respond to treatment, and it doesn't involve any extra drugs or procedures—just blood draws.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07151885Recruiting
Using ultrasound and blood tests to predict varices risk in cirrhosis
This trial tests if a special ultrasound technique combined with liver stiffness and platelet count can predict which patients with cirrhosis have high-risk varices in the esophagus or stomach, potentially reducing the need for repeated endoscopy.
Changchun, JilinAges 18 years+ - NCT07152431Recruiting
Using a special scan to find scar tissue in Crohn's disease
This study uses a special imaging tracer (FAPI) to find scar tissue in the small intestine of people with Crohn's disease. The goal is to see if this scan can help doctors better understand which parts of the intestine are scarred, which may guide treatment decisions.
EdinburghAges 18–90 - NCT07152678RecruitingPhase 2
Brachytherapy with radiation and immunotherapy for esophageal cancer
This trial tests combining brachytherapy (a type of internal radiation) with immunotherapy (nivolumab) for people with advanced esophageal cancer that has not fully responded to initial chemoradiation. The goal is to see if this targeted approach can improve outcomes.
Huwei, Yunlin CountyAges 18–85 - NCT07152834Recruiting
Screening for Alpha-1 Antitrypsin Deficiency in Lung Blockage
This study screens for a rare genetic condition called Alpha-1 Antitrypsin Deficiency in people with lung blockage. It aims to find out if this deficiency is a hidden cause of your breathing problems, which could lead to better treatment options.
Muğla, MenteşeAges 18 years+ - NCT07153016Recruiting
Legal support for caregivers of colorectal cancer patients
This study tests whether giving legal advice and support to caregivers of people with advanced colorectal cancer can help them feel less stressed and more prepared. It is a small first test to see if this kind of help works and is practical.
Minneapolis, MinnesotaAges 18 years+ - NCT07153458Recruiting
Finding new markers for colorectal cancer
This trial is looking for new, non-invasive markers to help detect and predict colorectal cancer. Researchers will study people with colorectal cancer, those with precancerous growths, and healthy people to find better ways to diagnose the disease.
Castellana GrotteAges 18 years+ - NCT07153614Recruiting
Pain management after cancer surgery to start chemo sooner
This trial compares different methods of managing pain after cancer surgery to see which helps patients start chemotherapy sooner. It focuses on people having open abdominal surgery for certain cancers who are scheduled for chemotherapy afterward.
Knoxville, TennesseeAges 18–80 - NCT07153692Recruiting
Brain stimulation for swallowing problems in Parkinson's
This study is testing whether a gentle brain-stimulation technique called tDCS can help people with Parkinson's disease who have trouble swallowing. If you have Parkinson's, multiple system atrophy, or progressive supranuclear palsy and a swallowing problem, this trial may be an option.
Hangzhou, ZhejiangAges 18–100 - NCT07153809Recruiting
Fecal transplant for severe acute pancreatitis recovery
This trial tests whether a fecal transplant (transferring healthy gut bacteria from a donor) can help people with severe acute pancreatitis. It is for adults who are about 2 weeks past the onset of the disease and have started to recover but still have fluid buildup in the pancreas.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07154082RecruitingPhase 2
Combination therapy before surgery for liver cancer
This trial tests if giving a combination of drugs (apatinib and camrelizumab) along with a procedure called TACE before surgery can help treat a certain type of liver cancer. The goal is to shrink the tumor before the operation to improve outcomes.
Wuhan, HubeiAges 18–70 - NCT07154173Recruiting
Gut bacteria study in metastatic colorectal cancer
This study looks at gut bacteria in people with colorectal cancer that has spread (metastatic). It aims to find patterns in the bacteria that may help doctors choose better treatments.
Guangzhou, GuangdongAges 18–75 - NCT07154316RecruitingPhase 2
Short radiation plus drugs for MSS rectal cancer
This trial tests a shorter course of radiation therapy followed by a combination of chemotherapy, immunotherapy, and a pain-relief medication, compared to the standard approach. It is for people with a certain type of rectal cancer that has not spread.
Fuzhou, FujianAges 18–75 - NCT07155148Recruiting
Argentine registry for Crohn's and colitis patients
This study collects information from people diagnosed with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. By joining the registry, you help researchers learn more about these conditions and improve care.
Córdoba, Córdoba ProvinceAges Any age - NCT07155525RecruitingPhase 3
Glue to prevent leaks after pancreas surgery
This trial tests whether a special medical glue (Glubran® 2) applied to the pancreas during surgery can help prevent fluid leaks. It is for people undergoing a Whipple procedure for pancreatic cancer who have a soft pancreas.
Minya, Minya GovernorateAges 18–75 - NCT07156058Recruiting
Personalized therapy after surgery for bile duct cancer
This trial uses a test called MiniPDX, which grows a tiny sample of your tumor in mice to see which drugs work best. After your surgery, you'll receive chemotherapy chosen specifically for your cancer to help prevent it from coming back.
BeijingAges 18 years+ - NCT07156175RecruitingPhase 2
Study of new treatment for microscopic colitis in remission
This study tests whether a new medication (SAR444336) can help adults with microscopic colitis stay in remission longer. It may be an option if you are already taking budesonide and have had flares in the past 8 months.
GhentAges 18 years+ - NCT07157631Recruiting
Tranexamic acid for adults having liver transplant
This trial tests if tranexamic acid, a medicine that helps blood clot, can safely reduce bleeding during adult liver transplant surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07157969RecruitingPhase 2
Immunotherapy and anti-VEGF with or without local therapy for liver cancer
This trial tests a combination of immunotherapy (checkpoint inhibitors) and anti-VEGF therapy (which blocks blood vessel growth to tumors) with or without local treatments (like chemoembolization) for advanced liver cancer. It aims to see if the combination works better than current treatments.
BeijingAges 18 years+ - NCT07158008Recruiting
Weight loss surgery for people with obesity and heartburn
This study compares two weight-loss surgeries for people who have both obesity and severe heartburn or GERD. One surgery combines part of the stomach removal with an anti-reflux wrap, while the other reroutes the stomach to help with weight loss and reflux.
KrakowAges 18–65 - NCT07158164RecruitingPhase 4
Genetic testing for chemotherapy dose adjustment
This trial checks if adjusting the dose of chemotherapy drugs 5-FU or capecitabine based on your DPYD genetic results can improve safety and effectiveness. It’s for people with cancer who are about to start these drugs for the first time.
Belleville, New JerseyAges 18 years+ - NCT07159334Recruiting
Lidocaine vs Nitroglycerin for Pain After Hemorrhoid Surgery
This study compares a lidocaine ointment versus a nitroglycerin (GTN) ointment for pain relief after hemorrhoid removal surgery. It aims to see which works better for patients with advanced hemorrhoids.
Lahore, Punjab ProvinceAges 18–60
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,903 recruiting gastroenterology studies from the U.S. registry right now, out of 12,451 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.