Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,916 recruiting studies in this area right now.
By phase
- Not applicable4,936
- Phase 21,188
- Phase 1583
- Phase 3465
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer148
- Crohn Disease144
- Ulcerative Colitis140
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)107
- Liver Cancer101
- Lung Cancer99
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California461
- Arizona174
- Texas148
- Florida135
- Massachusetts127
- Alabama123
- New York123
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,916 total
- NCT06396806Enrolling by invitation
Sigmoid cancer surgery with or without dye tracing
This trial compares two surgical approaches for sigmoid colon cancer to see if using a special dye to see lymph nodes during surgery leads to better outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06391749Enrolling by invitation
Blood test for multiple cancers in people with symptoms
This trial tests a new blood test (SPOT-MAS) that looks for signs of multiple cancers in people who already have symptoms and are being checked with imaging. If the blood test is positive, you'll get more detailed scans or a biopsy to see if cancer is present.
Ho Chi Minh CityAges 18 years+ - NCT06381882Enrolling by invitation
Human microbiome study after pancreatic surgery
This study looks at how tiny organisms in your gut (the microbiome) affect recovery after surgery for pancreatic cancer or related growths. It may help doctors understand how to improve outcomes for future patients.
NieuwegeinAges 18 years+ - NCT06335862Enrolling by invitation
Surgery to stop windpipe collapse in babies with esophageal atresia
This trial tests a surgery called posterior tracheopexy to prevent the windpipe from collapsing in babies with esophageal atresia and tracheomalacia. It may help your child breathe more easily.
RotterdamAges 8 months+ - NCT06334666Enrolling by invitation
Step counting for fatty liver disease management
This trial tests if using a pedometer to track daily steps can help people with a type of fatty liver disease (called MASLD) become more active and improve their health. It may be a good fit if you are not already very active and want to try a simple way to manage your condition.
Bangkoknoi, BangkokAges 18 years+ - NCT06303583Enrolling by invitationPhase 1/Phase 2
Chemo-radiation followed by immunotherapy for esophageal cancer
This trial tests if giving chemotherapy and radiation before surgery, followed by immunotherapy, can improve outcomes for people with a specific type of esophageal cancer that can be surgically removed.
Hangzhou, ZhejiangAges 18–75 - NCT06283576Enrolling by invitation
Pancreatic cancer early detection with blood test
This trial studies a blood test to find pancreatic cancer early. It may help people who are at risk or have suspicious signs.
StockholmAges 18 years+ - NCT06276764Enrolling by invitation
A study tracking a new procedure for pancreatic cysts (IPMN)
This study follows patients with a type of pancreatic cyst called IPMN who receive the LINFU procedure, a treatment that uses sound waves and microbubbles. Researchers want to see how well it works and monitor safety.
New York, New YorkAges 18–90 - NCT06276140Enrolling by invitation
Iron deficiency anemia and recovery after colorectal cancer surgery
This study looks at how iron deficiency anemia affects recovery after surgery for colorectal cancer. It may help doctors understand if treating this type of anemia before surgery improves outcomes.
KamenitzAges 18 years+ - NCT06269744Enrolling by invitation
Proactive outreach with stool test for colorectal cancer screening
This study reaches out to adults aged 45–75 who are due for colorectal cancer screening. It uses a simple stool test (FIT) to help find cancer early and is offered at certain NYU Langone clinics.
Brooklyn, New YorkAges 45–75 - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Birmingham, AlabamaAges 6 years+ - NCT06242613Enrolling by invitation
Robot vs. laparoscopic surgery for stomach cancer
This study compares robot-assisted surgery to standard laparoscopic surgery for people with stage Ib, II, or III stomach cancer. It aims to see which approach leads to better recovery and outcomes.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06240065Enrolling by invitation
Fiber food trial for short bowel syndrome
This study tests if adding high-fiber foods can help people with short bowel syndrome (a condition where part of the small intestine is missing or removed). You will be asked to eat fiber-rich foods and the study team will see how your body handles them.
Dallas, TexasAges 4 months–17 years - NCT06223022Enrolling by invitation
Nurse phone calls after cancer treatment ends
This trial tests whether regular phone calls from a nurse can help patients after they finish their main cancer treatment. It focuses on breast, colorectal, or prostate cancer that was treated with a goal to cure.
UmeåAges 18 years+ - NCT06215547Enrolling by invitation
Nerve stimulator for nausea and vomiting
This trial tests a device that sends mild electrical pulses to the stomach to help control severe nausea and vomiting caused by gastroparesis (stomach that empties slowly). It is for people aged 18–70 whose symptoms have not improved with medication.
Richardson, TexasAges 18–70 - NCT06191185Enrolling by invitation
Improving colonoscopy follow-up after abnormal FIT
This trial tests a program to help people who had an abnormal FIT stool test follow through with getting a colonoscopy. The goal is to improve cancer screening by providing extra support through a care team and technology.
San Francisco, CaliforniaAges 18 years+ - NCT06179563Enrolling by invitation
On-demand app for IBD patients in remission
This trial tests an app that lets you check in with your IBD care team only when you need to, instead of having regular appointments. It's for people with Crohn's disease or ulcerative colitis who are doing well and have been on the same medication for at least 3 months.
's-Hertogenbosch, North BrabantAges 18 years+ - NCT06165289Enrolling by invitation
Balloon dilation with PRP for Crohn's colon narrowing
This trial tests whether adding a platelet-rich plasma (PRP) injection to the standard balloon dilation procedure can help treat a narrowed section of the colon caused by Crohn's disease. It may offer a way to avoid or delay surgery for some patients.
Guangzhou, GuangdongAges 18 years+ - NCT06160557Enrolling by invitation
Radiation after endoscopic surgery for superficial esophageal cancer
This trial tests if adding radiation therapy after endoscopic surgery (ESD) helps people with early-stage esophageal cancer that had certain high-risk features, like deeper invasion or positive margins. It aims to improve outcomes for those who didn't get a complete cure with surgery alone.
Fuzhou, FujianAges 18–75 - NCT06152991Enrolling by invitationPhase 3
Godex for fatty liver: a Phase 3 trial
This study tests an investigational supplement called Godex Carnitine Orotate Complex to see if it helps people with nonalcoholic fatty liver disease (NAFLD) lower their liver enzymes and reduce liver fat. It may be a good option if you have elevated liver enzymes and evidence of fat in your liver.
SeoulAges 19–74 - NCT06133439Enrolling by invitation
Colorectal cancer screening study for rural Indiana
This study tests a way to improve colorectal cancer screening for people in rural Indiana. It looks at how to better reach those who are due for screening, which can help catch cancer early or prevent it.
Monroe, IndianaAges 45–75 - NCT06132048Recruiting
Testing a smartphone app for cystic fibrosis
This study tests a smartphone app called MuCopilot that helps you track your cystic fibrosis symptoms at home. Researchers want to see if the app is easy to use and can give accurate information about your condition.
RouenAges 18 years+ - NCT06094504Enrolling by invitation
Light therapy for babies with intestinal failure
This study tests whether a special kind of lighting can help babies with intestinal failure. If your baby is born at or after 32 weeks and has or is expected to have intestinal failure, this study may be an option.
Cincinnati, OhioAges Up to 1 year - NCT06090994RecruitingPhase 4
Huaier vs capecitabine to prevent colon cancer return
This study compares two medicines to prevent colorectal cancer from coming back after surgery: a traditional Chinese medicine called Huaier and a standard chemotherapy pill called capecitabine. It is for people with stage 2 colon cancer that was completely removed.
Harbin, HeilongjiangAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,916 recruiting gastroenterology studies from the U.S. registry right now, out of 12,516 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.