Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,879 recruiting studies in this area right now.
By phase
- Not applicable4,909
- Phase 21,183
- Phase 1583
- Phase 3465
- Phase 1/Phase 2392
- Phase 4235
- Phase 2/Phase 3112
Top conditions
- Colorectal Cancer494
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer146
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer100
- Lung Cancer99
- Pancreas Cancer94
- Ovarian Cancer90
- Esophageal Squamous Cell Carcinoma88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University90
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center59
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California463
- Arizona177
- Texas147
- Florida134
- Massachusetts128
- New York123
- Alabama122
- Maryland86
- Ohio78
- Pennsylvania72
Recruiting studies7,879 total
- NCT07461233Recruiting
Gut Health and Synbiotics in Hemodialysis
This study tests whether taking a special mix of friendly bacteria and prebiotics (called synbiotics) can help improve gut health in people on hemodialysis. It may reduce inflammation and other complications related to kidney disease.
Taichung, Wuqi DistrictAges 18 years+ - NCT06484660Recruiting
Less invasive surgery for complex anal fistula
This study tests a less invasive surgical method (a mucosal advancement flap) for treating complex anal fistulas. It aims to see if this approach works well for people who have a single fistula tunnel and haven't had this type of operation before.
Palma de Mallorca, Balearic IslandsAges 18 years+ - NCT06481072Recruiting
Digital therapy for kids with chronic stomach pain
This trial tests a digital (online) therapy program to help children with chronic stomach pain. It's designed for kids ages 8 to 14 who have been diagnosed with a functional abdominal pain disorder and can use a computer or tablet at home.
GothenburgAges 8–14 - NCT07465705RecruitingPhase 3
Comparing two bowel prep options for colonoscopy the same day
This trial compares two different bowel cleansing preparations taken the same day as your colonoscopy: mannitol vs Plenvu. It aims to see which one works best and is safe.
AnderlechtAges 18 years+ - NCT06617182RecruitingPhase 2
Thalidomide and glutamine for radiation bowel injury
This trial tests whether combining thalidomide and glutamine helps people with bleeding caused by past radiation treatment to the abdomen or pelvis. The medication may reduce inflammation and help healing.
Xi'an, ShaanxiAges 18–80 - NCT06464822Recruiting
Effects of weight-loss surgery on urinary symptoms
This study looks at whether weight-loss surgery can improve urinary symptoms like needing to pee often or suddenly. It is for people with severe obesity who are already being seen at a specific clinic for bariatric surgery.
Hong KongAges 18 years+ - NCT07337811Recruiting
Selective removal of rectal cancer after radiation and chemotherapy
This trial tests how well a precise surgery removes the remaining rectal cancer after you have had radiation and chemotherapy. It is for people whose tumor has shrunk a lot but is still there, and the tumor is very low in the rectum.
Guangzhou, GuanggongAges 18–75 - NCT04708288Recruiting
Study of a dissolving bile-duct stent
This study tests a new type of stent that dissolves over time for the bile or pancreatic duct. It aims to see if the stent is safe and works well.
HelsinkiAges 18 years+ - NCT06446050RecruitingEarly Phase 1
Modified stem cells for advanced colorectal cancer
This trial tests a new treatment using special stem cells (modified to boost your immune system) for people with advanced colorectal cancer. It is for patients who are 18 or younger and whose cancer has not responded to or cannot be treated with standard therapies.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06215404Recruiting
Fluid management during liver transplant for less blood loss
This trial tests different ways of managing fluids during liver transplant surgery to see if it can reduce blood loss. It may be helpful for patients with end-stage liver disease who are waiting for a transplant.
TaipeiAges 18–75 - NCT06420258RecruitingPhase 4
Deeper intubation for cervical esophageal cancer removal
This study tests if inserting the endoscope deeper helps remove early-stage cervical esophageal cancer or precancerous cells more effectively. It may offer a safer, less invasive option for you.
Fuzhou, FujianAges 18–80 - NCT07459504RecruitingPhase 2
Smart diets for kids with fatty liver disease
This study compares different diet plans to see which works best to reduce fat in the liver of children and teens with MASLD (a type of fatty liver disease). If your child drinks sugary beverages often and has certain health risks like being overweight or having high cholesterol, this trial may help find a healthy eating plan that works.
Grand Rapids, MichiganAges 11–17 - NCT06968234Recruiting
Liver disease breath test study
This study uses a special breath test to learn about chronic liver disease. If you have liver disease or cirrhosis, you may be able to help by providing a breath sample.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06970678RecruitingPhase 1/Phase 2
A new way to ease pain and speed recovery after sleeve gastrectomy
This study tests whether adding two pain-management methods—a sedative infusion and a nerve block around the stomach—can help you recover faster and more comfortably after sleeve gastrectomy surgery. If you're eligible, you'll receive the extra treatment on top of standard anesthesia.
AlexandriaAges 18–60 - NCT06382012RecruitingPhase 2/Phase 3
Fosaprepitant for nausea in the emergency room
This study tests if a drug called fosaprepitant can help people in the emergency room whose nausea and vomiting don't improve with standard medicine. It may be an option if you still feel sick 2 hours after your first nausea treatment.
The Bronx, New YorkAges 18 years+ - NCT05632861RecruitingPhase 2
Trial drug for biopsy-proven nonalcoholic steatohepatitis
This Phase 2 trial studies HuHuangLianzonggan Capsule to treat nonalcoholic steatohepatitis (NASH), a liver inflammation caused by fat buildup. You may be eligible if you have confirmed NASH on a recent liver biopsy and meet specific liver fat, lab, and health-condition limits.
Hefei, AnhuiAges 18–75 - NCT06986447Enrolling by invitation
Non-invasive tests for serious liver disease
This study is testing whether advanced imaging and other non-invasive methods can properly identify people with significant liver scarring due to metabolic liver disease or alcohol-related liver disease. It may help find better ways to track liver health without repeated needle biopsies.
Chandler, ArizonaAges 18–80 - NCT06364306Recruiting
Open vs. robotic repair for medium to large belly hernias
This trial compares two ways to repair medium to large ventral hernias (bulges in the belly wall): open surgery (with a cut) versus robotic-assisted surgery (using small tools and a camera). The goal is to see if the robotic approach leads to better recovery.
Kempten (Allgäu), BavariaAges 18 years+ - NCT06367309Recruiting
Comparing two mesh techniques for ventral hernia repair
This trial is comparing two minimally invasive surgery techniques for fixing ventral hernias (a bulge in your belly wall). One technique places the mesh inside the belly, the other places it outside the belly lining. The goal is to see which approach leads to better recovery.
Basel, Canton of Basel-CityAges 18 years+ - NCT06356545Recruiting
Study of children with chronic diarrhea in China
This study looks at children with ongoing diarrhea to better understand the causes and find better ways to diagnose and treat it. It will use advanced testing to learn more about the condition.
Shanghai, Shanghai MunicipalityAges 1 month–3 years - NCT06340217Recruiting
Washed Microbiota Transplant for Diabetic Stomach Paralysis
This trial tests a new treatment called washed microbiota transplantation for diabetic gastroparesis, a condition where the stomach empties slowly due to diabetes. If you have had diabetes for over a year and struggle with bloating or feeling full quickly, this study may explore whether transplanting healthy gut bacteria can help relieve your symptoms.
Nanjing, JiangsuAges 18–100 - NCT06349486Recruiting
Comparing new treatments for H. pylori infection
This trial compares three different medication combinations to see which works best for treating H. pylori infection. If you have H. pylori and haven't been treated yet, you may be able to join.
Kaohsiung CityAges 18 years+ - NCT06347770RecruitingPhase 1
Oral Gan Shuangbi for recovery after C-section
This trial tests an oral herbal medicine (Gan Shuangbi) to see if it helps your intestines work normally again after a C-section. It may speed up recovery after delivery.
Guangzhou, GuangdongAges 18–45 - NCT06614036RecruitingPhase 4
Remimazolam vs. Midazolam for sedation during upper GI endoscopy
This study compares two different sedative medicines, remimazolam and midazolam, to see which works better for people having a routine upper GI endoscopy (a camera test to look at your stomach and esophagus). If you are scheduled for this procedure and need sedation, you may be able to join.
Apeldoorn, GelderlandAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,879 recruiting gastroenterology studies from the U.S. registry right now, out of 12,351 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.