Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT06966518Recruiting
Ketamine and magnesium for pain control after nose surgery
This study tests whether giving a combination of two medicines (ketamine and magnesium sulfate) during nose surgery can help reduce pain after the operation. It may be a good option for healthy adults having rhinoplasty and looking for better pain control.
CairoAges 18–65 - NCT07569952Recruiting
Nerve Block to Improve Surgical Field in Pituitary Surgery
This trial tests whether blocking a specific nerve in the face (sphenopalatine ganglion) during pituitary tumor surgery improves the surgeon's view and reduces bleeding. Pituitary adenomas are non-cancerous tumors in the brain that are removed through the nose using a camera.
CairoAges 1.8 years–60 years - NCT05913297Recruiting
Checking how Chiari malformation affects airways and sleep in children
This study looks at how Chiari malformation (types 1 and 2) may affect a child’s breathing/airways, the base of the skull, and sleep. The results may help doctors better understand which problems to watch for and how to evaluate them.
Rome, ItalyAges 3–18 - NCT07071298Recruiting
AERA pediatrics registry study
This registry tracks children who have a procedure called endoscopic transforaminal balloon dilation (ETBD) using the AERA device. The goal is to learn more about how this treatment works for young patients.
Palo Alto, CaliforniaAges Up to 18 years - NCT07569939Recruiting
Treatment options for sore throat from viral infection
This study tests different treatments to help ease sore throat pain and symptoms caused by viral throat infections. It aims to find the best way to relieve discomfort when you have pharyngitis, tonsillitis, or a viral sore throat that started recently.
Clermont-FerrandAges 18–70 - NCT07132827RecruitingPhase 3
Study of SHR-1905 for chronic sinusitis with nasal polyps
This trial tests a new injection (SHR-1905) for people with chronic sinusitis and nasal polyps who still have symptoms despite using standard nasal spray treatments. It aims to see if the drug can reduce polyp size and improve symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06981494Recruiting
Study of two medicines for relaxing blood pressure during ear and nose surgery
This trial tests if adding a second medicine, ketamine, to dexmedetomidine helps control blood pressure better during ear or nose surgery. It may lead to safer and smoother anesthesia for patients needing controlled low blood pressure.
SohagAges 18–60 - NCT06422793Recruiting
Does a stomach tube reduce nausea after jaw surgery?
This study tests whether using a thin tube through the nose into the stomach during jaw surgery helps reduce nausea and vomiting after the operation. It's for people having certain types of jaw surgery to correct bite or facial problems.
Halifax, Nova ScotiaAges 16 years+ - NCT06752863RecruitingPhase 4
Study of two drugs for controlled low blood pressure during surgery
This trial compares two medications, labetalol and dexmedetomidine, given as infusions to lower blood pressure during ear, nose, and throat surgeries. The goal is to find which drug works better and safer for patients.
Cairo, Cairo GovernorateAges 20–50 - NCT07317154RecruitingPhase 1
Dendritic cell vaccine for HPV type 6 recurrent respiratory papillomatosis
This Phase 1 trial is testing a vaccine made from your own immune cells (dendritic cells) that may help your body fight the virus causing recurrent papillomas in your voice box. It is for people whose papillomas are caused by HPV type 6, who have had at least one recurrence in the past year.
Scottsdale, ArizonaAges 18 years+ - NCT07010679Enrolling by invitation
How patients decide about sinus surgery
This study looks at how people with long-term sinus problems decide whether to have sinus surgery. Researchers want to understand what matters most to patients when choosing treatment.
Arcadia, CaliforniaAges 18 years+ - NCT05397769RecruitingPhase 2
Test envafolimab with chemoradiation for advanced nasopharyngeal cancer
This trial studies whether adding envafolimab (an immune medicine) to standard chemo and radiation works better for people with locally advanced, untreated nasopharyngeal cancer. It may help the immune system attack the cancer while treatment shrinks it.
Guangzhou, GuangdongAges 18–65 - NCT06958523Recruiting
Apple Health Study for US iPhone users
This study uses your iPhone and optional devices like Apple Watch to collect health data over time. It aims to discover how technology can help monitor and improve health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06961045Enrolling by invitation
Nerve repositioning study for dental implants in lower jaw
This study tests a computer-guided technique to move a nerve in the lower jaw so that dental implants can be placed in areas with thin bone. It looks at whether this procedure causes any numbness afterward.
Tanta, Gharbia GovernorateAges 30–75 - NCT06712979Recruiting
Adding breathing exercises to voice therapy for professionals
This study tests if adding a special breathing exercise (lung volume recruitment) to the Lee Silverman voice therapy program helps voice professionals improve their voice. You may be able to join if you're a voice professional with a healthy voice and no smoking history.
Anápolis, GoiásAges 20–60 - NCT07031349Recruiting
Sleep and airway changes from palate expander treatment
This study tests whether a special palate expander (MARPE) improves sleep and airway function in teenagers with a narrow upper jaw. It may help breathing during sleep.
Konya, MeramAges 15–18 - NCT07025304Recruiting
Study of REFLEX ULTRA 45 for nasal turbinate reduction in China
This trial tests a new device called REFLEX ULTRA 45 that uses radiofrequency energy to shrink the nasal turbinates (the fleshy shelves inside your nose) to help you breathe easier. It is for people with long-term nasal stuffiness who have not gotten relief from nasal sprays.
Guangzhou, GuangdongAges 18–65 - NCT05815927RecruitingPhase 3
Pembrolizumab with targeted radiation for limited head and neck spread
This Phase 3 trial studies whether adding pembrolizumab (an immune medicine) to focused radiation (SABR) can better control head and neck cancer that has spread to only 1–5 spots. It may help some people live longer or delay cancer worsening by treating both the immune system and the specific metastases.
BrusselsAges 18 years+ - NCT05435989Recruiting
High-frequency hearing and speech testing for American English speakers
This study looks at how well people with normal hearing can hear high-pitched sounds and understand speech. If you speak American English and your hearing is normal within a specific sound range, you may be able to take part.
Champaign, IllinoisAges 19–50 - NCT06431698Recruiting
Correcting ear shapes in newborns: comparing two methods
This trial tests two different ways to mold and fix ear deformities in newborns. If successful, your baby could have a more normally shaped ear without surgery.
Caen, NAges Up to 1 month - NCT07528183RecruitingPhase 2
Immunotherapy after chemo and radiation for recurrent nose cancer
This trial tests whether maintenance immunotherapy (PD-1 inhibitor) followed by delayed salvage radiation therapy can help keep your cancer under control after you have already responded to initial chemo-immunotherapy. It is for people with recurrent nasopharyngeal carcinoma that has come back in the nose or neck area, but has not spread to distant organs.
Fuzhou, FujianAges 18–70 - NCT07476209Recruiting
Salivary gland procedure vs light therapy for dry mouth from radiation
This trial compares two treatments—a salivary gland procedure (sialendoscopy) and a light therapy (photobiomodulation)—to prevent dry mouth caused by radiation therapy for head and neck cancer. If you are about to start radiation and meet the dose limits, you may be eligible.
AlexandriaAges 18 years+ - NCT07507578Recruiting
Biology study for head and neck adenoid cystic carcinoma
This study uses advanced tests on tissue and blood samples to understand why adenoid cystic carcinoma (a type of head and neck cancer) spreads. It aims to find new clues that may help improve future treatments.
MilanAges 18 years+ - NCT07498374Recruiting
Drug-eluting stent for eosinophilic sinusitis with nasal polyps
This trial tests a fully dissolvable stent that releases medication inside the sinuses after surgery. It is for patients with a specific type of sinusitis (eosinophilic) and nasal polyps who either need surgery or have had surgery and show early signs of inflammation returning.
Xi'an, ShaanxiAges 18–65
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.