Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06401993Recruiting
Brain connection study of tinnitus treatment with Chinese medicine
This study tests a traditional Chinese medicine treatment called 'Dao qi Tong Luo' for chronic tinnitus. It uses a safe brain scan (fNIRS) to see how the treatment affects brain connections related to hearing.
HangzhouAges 20–55 - NCT06714149Recruiting
How nitrogen pollution affects pollen allergies
This study looks at how pollution from nitrogen in the environment affects pollen allergies in Belgium. It may help explain why your allergy symptoms change depending on where you live.
Leuven, Vlaams-BrabantAges 18 years+ - NCT03916809Recruiting
Voice and swallowing therapy device during head and neck cancer treatment
This trial tests whether using a mouth-based training device (called EMST150) during planned radiation (with or without chemotherapy) can help people with head and neck cancer with swallowing and related muscle function. It may be useful if you’re starting radiation for a cancer in the mouth, throat, or voice box area.
Milwaukee, WisconsinAges 18 years+ - NCT04083417RecruitingPhase 4
Sore throat study comparing antibiotics versus no antibiotics
This trial looks at whether phenoxymethylpenicillin (an antibiotic) helps people with a certain type of sore throat more than not using antibiotics. You may qualify if your symptoms match a likely bacterial cause and a rapid test for strep is negative.
JönköpingAges 15 years+ - NCT06716125Recruiting
Lifestyle changes for obese men with sexual and hearing issues
This trial tests whether lifestyle changes can help obese men who have both sexual difficulties and ringing in the ears. It might improve your overall health and these symptoms.
Dokki, Giza GovernorateAges 35–45 - NCT07599696Recruiting
Speech Amplification Devices for Parkinson Disease
This research study tests special amplification devices designed to help people with Parkinson disease or related conditions speak more clearly. The goal is to improve how well others can understand your speech.
East Lansing, MichiganAges 50 years+ - NCT07601412Recruiting
Understanding Immune Response to Respiratory Viruses in Older Adults
This study examines how the body's natural defense system (specifically a type of immune protein) responds to common respiratory viruses like flu and cold in older adults. Researchers will analyze nasal samples that are already being collected as part of routine care to better understand why older people sometimes have different immune responses to these infections.
LyonAges 60 years+ - NCT07603167Enrolling by invitation
Photon-Counting CT Scans for Laryngeal Cancer Staging
This study tests a new type of CT scanner (photon-counting CT) to better visualize laryngeal cancer before surgery. The goal is to improve how doctors stage and plan treatment for throat cancer.
RozzanoAges 18 years+ - NCT07588672Recruiting
Allergy Blocker Spray for Seasonal Nasal Allergies
This trial tests whether PL-14, a new nasal spray, works better than saline spray at relieving seasonal allergy symptoms like sneezing, itching, and congestion. If it works well and is safe, it could offer patients a new way to manage allergies during pollen season.
Normal, IllinoisAges 18–75 - NCT07590024RecruitingPhase 3
Personalized Cancer Treatment Guidance for Nasopharyngeal Cancer
This trial tests whether a special analysis of blood markers and imaging scans can help doctors choose the best combination of chemotherapy and radiation for nasopharyngeal cancer. The goal is to improve outcomes by tailoring treatment to each patient's specific cancer characteristics.
Beijing, Beijing MunicipalityAges 18–65 - NCT06427577Recruiting
Study of ZhenQiFuZheng for allergic rhinitis
This trial tests if a traditional Chinese medicine called ZhenQiFuZheng can help people with allergic rhinitis by changing their gut bacteria. Researchers will collect samples to understand how it works.
Nanjing, JiangsuAges 18–65 - NCT07584499RecruitingPhase 1
New drug test for children with EGFR-positive solid tumors
This study tests a new cancer drug called Becotatug Vedotin in children ages 2–18 with certain types of solid tumors (cancers that form in organs or tissues) that have an EGFR protein. The drug is designed to find tumors with this protein and attack cancer cells while sparing healthy ones.
Guangzhou, GuangdongAges 2–18 - NCT07581821RecruitingPhase 2
Immunotherapy plus targeted drugs for advanced nasopharyngeal cancer
This trial tests a combination of three drugs (sintilimab, anlotinib, and chemotherapy) for nasopharyngeal cancer that has returned or spread after initial treatment. The goal is to see if this combination helps slow or shrink the cancer.
Zhuhai, GuangdongAges 18–65 - NCT07579364Enrolling by invitation
Voice Outcomes After Vocal Cord Surgery
This study follows people who have had surgery to improve one-sided vocal cord paralysis or atrophy—a condition where one vocal cord doesn't move properly or has shrunk. Researchers track how well your voice works and your quality of life over 2 years after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT03988764Recruiting
Checking monogenic diabetes wrongly labeled as type 1
This trial looks at people who were diagnosed with diabetes before age 25 as either type 1 or “not sure which type.” It may help confirm whether the cause is genetic (monogenic) rather than type 1, which can change treatment choices.
Montreal, QuebecAges 1 day–25 years - NCT06725966Recruiting
Personalized treatment for persistent BPPV
This trial tests a new way to treat a common inner ear condition called BPPV that hasn't improved with standard head maneuvers. It aims to help people whose dizziness keeps coming back.
Santiago de Compostela, A CoruñaAges 18–100 - NCT06725979Recruiting
Palatal expansion for sleep disorders in children
This trial tests if a treatment that widens the upper jaw (palatal expansion) can improve sleep problems in children who have a narrow upper jaw.
Rijeka, Primorje-Gorski Kotar CountyAges 2–18 - NCT04855838Recruiting
Study of swallowing problems after neck spine surgery
This study looks at how swallowing recovers after surgery on the front of the neck spine after a trauma. Some people may also be followed more closely if a swallowing test shows a problem a few weeks after surgery.
UmeåAges 18 years+ - NCT06726005Recruiting
3D jaw study for sleep breathing problems
This study looks at how a small lower jaw and large overbite relate to sleep-related breathing issues, using 3D scans and functional appliances.
Rijeka, Primorje-Gorski Kotar CountyAges 10–14 - NCT06726551Recruiting
AI to recognize key structures in ear surgery
This study uses artificial intelligence to analyze videos from ear surgeries that were done under a microscope. It aims to help doctors better identify important structures during operations.
Guangzhou, GuangdongAges 6 months–100 years - NCT07572357Recruiting
Testing a New Self-Fit Hearing Aid with a Smartphone App
This study evaluates the RH210 hearing aid, which you fit yourself using a smartphone app. It's designed for people with mild-to-moderate hearing loss who want a simpler, app-based approach to managing their hearing.
Macquarie Park, New South WalesAges 18 years+ - NCT07574476Enrolling by invitation
Fasting Time and Pain After Tonsil Surgery
This study looks at whether the length of time patients fast (don't eat or drink) before tonsil removal surgery affects how much pain they experience afterward. Researchers hope to find the best fasting approach to reduce post-surgery discomfort.
Columbus, OhioAges Up to 18 years - NCT07569952Recruiting
Nerve Block to Improve Surgical Field in Pituitary Surgery
This trial tests whether blocking a specific nerve in the face (sphenopalatine ganglion) during pituitary tumor surgery improves the surgeon's view and reduces bleeding. Pituitary adenomas are non-cancerous tumors in the brain that are removed through the nose using a camera.
CairoAges 1.8 years–60 years - NCT07575334Recruiting
Acupuncture for sudden hearing loss
This trial tests whether acupuncture can help restore hearing in people who suddenly lost hearing in one ear within the past few days. If you've had sudden unexplained hearing loss, this study may help determine if acupuncture is an effective treatment.
ShanghaiAges 18–70
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.