Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT07565753RecruitingEarly Phase 1
Testing a medication to stop bleeding after tonsil removal
This study tests a medicine called tranexamic acid to help stop bleeding in children who had their tonsils removed and are now bleeding more than a day after surgery. Researchers want to see if this medicine can reduce the amount of bleeding and help children recover faster.
Davis, CaliforniaAges 2–17 - NCT07154121Recruiting
5-FU added to tear duct surgery for small tear sacs
This study tests if adding a medicine called 5-FU to standard tear duct surgery helps people with a small tear drainage sac get better results. It might be an option if you have a blocked tear duct and a very small sac.
Guangzhou, GuangdongAges 18 years+ - NCT06161779Recruiting
Reconstructing the hypopharynx after cancer removal
This trial tests a surgical technique using a flap from under your chin to rebuild the hypopharynx after removing cancer. It may help people with hypopharyngeal cancer that has not spread far and who have not had radiation before.
Guangzhou, GuangdongAges 18–80 - NCT07529392Recruiting
Ear nerve stimulation plus rehabilitation for chronic back pain
This trial tests a non-surgical treatment that stimulates a nerve in your ear while you do rehabilitation exercises to reduce chronic back pain. It may help if you've had pain for more than 6 months and pain medications aren't working well enough.
Baden, Lower AustriaAges 30–65 - NCT06306846RecruitingPhase 2
Radiation and immunotherapy before surgery for head and neck cancer
This study tests giving a short course of targeted radiation (SBRT) along with immunotherapy and a targeted drug before surgery for advanced head and neck cancer. The goal is to see if this combination can shrink the tumor and improve outcomes.
Hangzhou, ZhejiangAges 18–70 - NCT07553247Recruiting
Comparing two airway tubes for young children under anesthesia
This study compares two types of soft breathing tubes (laryngeal mask airways) used during surgery in children ages 3–6. Researchers want to see which one works better and is safer for keeping the airway open during anesthesia.
Zagazig, Sharqia ProvinceAges 3–6 - NCT06331351Recruiting
Herbal tea for chronic throat irritation
This trial tests whether a special herbal tea (Jing Si Herbal Tea) can help people with chronic pharyngitis (long-term throat irritation). It aims to see if the tea packets can soothe symptoms and improve throat health.
Chiayi CityAges 20–70 - NCT06275269Recruiting
Comparing two ways to inject steroids for throat narrowing
This trial tests two methods of injecting triamcinolone (a steroid) into the narrowed part of the throat (subglottic stenosis) to see which works better: one guided by a camera during an endoscopy, the other guided by ultrasound. It may help people who have trouble breathing or a hoarse voice due to this condition.
Beijing, Beijing MunicipalityAges 18–65 - NCT07033039Recruiting
Light therapy after nose surgery (rhinoplasty)
This study tests whether using red and infrared light therapy (called photobiomodulation) right after nose surgery can help you heal faster and reduce swelling, bruising, and pain. It is for people who are having a rhinoplasty and are otherwise healthy.
São Paulo, São PauloAges 18–60 - NCT07059195Recruiting
Keeping Neck Bent After Windpipe Surgery
This study tests two simple, non-invasive methods to keep your neck in a comfortable bent position after windpipe surgery. The goal is to reduce tension where the windpipe is reconnected, which may help the area heal better.
SohagAges 6 months–80 years - NCT07177586Recruiting
Comparing two types of laryngeal mask airways for surgery
This trial compares a newer laryngeal mask airway (a device that helps you breathe during surgery) with the traditional inflatable one. It aims to see which one works better and may be more comfortable for patients having routine surgery.
Hangzhou, ZhejiangAges 18–75 - NCT07492914RecruitingPhase 2
Study of pre-surgery drugs for head and neck cancer
This trial tests two medications given before surgery for head and neck cancer. The goal is to see if shrinking the tumor beforehand improves outcomes. If you have operable head and neck squamous cell cancer and are generally healthy, you may be eligible.
Chengdu, SichuanAges 18 years+ - NCT04290130Enrolling by invitation
Study brain signals during audiovisual speech in neurosurgery patients
This study measures brain activity to understand how your brain combines what you see and hear during speech. It may help scientists build better ways to understand and treat problems with speech processing.
Philadelphia, PennsylvaniaAges 21–65 - NCT06959082RecruitingPhase 2
Testing an experimental drug with chemoradiation for head and neck cancer
This trial tests an experimental drug called VS-101 combined with standard radiation and chemotherapy for people with advanced head and neck cancer that hasn't been surgically removed. The goal is to see if adding this drug helps the treatment work better while keeping side effects manageable.
New Haven, ConnecticutAges 18 years+ - NCT07114744Recruiting
Early cochlear implant use trial
This trial studies how well people new to cochlear implants understand speech over time. It may help you if you have severe hearing loss and are about to get a cochlear implant for the first time.
New York, New YorkAges 18–85 - NCT07168473RecruitingPhase 3
A study of DW1807 for year-round allergies and asthma
This trial tests a new medicine called DW1807 for people who have both year-round allergies (like dust mites or pet dander) and asthma. It aims to see if it helps control nasal symptoms and is safe to use.
SeoulAges 19 years+ - NCT07560280Recruiting
Tinnitus from Jugular Vein Narrowing: Diagnosis and Surgery Study
This study evaluates whether neck vein narrowing causes a specific type of tinnitus (ringing in the ears) and tests surgical treatment. If you have persistent tinnitus and imaging shows a narrowed jugular vein, this trial may help determine if surgery could help.
Beijing, Beijing MunicipalityAges 18–75 - NCT05865028RecruitingPhase 2
Test drug APG-157 for abnormal mouth tissue
This Phase 2 trial studies whether APG-157 can safely improve abnormal cells in the mouth (dysplasia) or early cancer-like changes (carcinoma in situ). You may be eligible if you have a visible, biopsy-proven lesion and can take oral medication while meeting blood and health requirements.
Miami, FloridaAges 18 years+ - NCT07533071Recruiting
Study of Timing in Getting Hearing Aid Help
This research examines how delays in getting hearing aids or other listening devices affect people's everyday communication and quality of life. Understanding this may help doctors better support people with hearing loss.
Chicago, IllinoisAges 18 years+ - NCT06248944Recruiting
Italian registry for head and neck cancers
This registry collects information from Italian hospitals about people with head and neck cancers. By joining, you help doctors better understand the disease and improve future treatments.
CandioloAges 18 years+ - NCT06732440Recruiting
Gentle motion therapy for balance problems
This study tests if mild, gentle head movements can help improve your balance and reduce dizziness. It is for people whose balance organs are not working well on one or both sides.
Omaha, NebraskaAges 19–89 - NCT06152627Recruiting
Voice Therapy for Muscle Tension Dysphonia
This study tests a new way of doing voice therapy for people with muscle tension dysphonia — a condition where the muscles around the voice box are too tight, making it hard to speak clearly. The goal is to see if this structured approach helps improve voice function.
Atlanta, GeorgiaAges 14 years+ - NCT06999044Recruiting
Improving chronic rhinitis diagnosis with a nasal allergy test
This study uses a nasal allergen provocation test to help diagnose chronic rhinitis more accurately. If you have allergic rhinitis or are a healthy volunteer, you may help researchers learn how well this test works.
Nanjing, JiangsuAges 18–75 - NCT07392320RecruitingPhase 2
Immunotherapy or chemo pills after chemoradiation for high-risk nasopharyngeal cancer
This trial compares two options—a type of immunotherapy or a chemotherapy pill (capecitabine)—as maintenance treatment after standard chemoradiation for high-risk nasopharyngeal cancer. It aims to see which helps prevent the cancer from coming back.
Guangzhou, GuangdongAges 18–70
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.