Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07635368Recruiting
Blood Markers in Newborns With CMV Infection
This research study examines blood samples from newborns to identify biological markers (proteins and genetic signals) that could help detect and understand congenital cytomegalovirus (CMV) infection—a virus some babies are born with. Finding these markers might help doctors identify infected infants earlier and develop better treatments.
CopenhagenAges birth–4 weeks - NCT06689865Recruiting
Hearing aid study for adults with mild to moderate hearing loss
This study tests four different ways to provide over-the-counter hearing aids to adults with mild-to-moderate hearing loss. It aims to find the best approach to help people hear better and improve their quality of life.
Aurora, ColoradoAges 40 years+ - NCT06695455Recruiting
Can music help people with Parkinson's swallow better?
This trial tests if a rhythmic sound cue can reduce rolling (a swallowing problem) in people with Parkinson's. If you have trouble with solid foods but not severe liquid aspiration, you may qualify.
Saint-Sébastien-de-Morsent, NormandyAges 18 years+ - NCT03480971RecruitingPhase 2
Tempol to reduce mouth and other side effects from radiation and cisplatin
This Phase 2 trial tests tempol to lessen harmful side effects caused by head-and-neck radiation and the chemotherapy drug cisplatin. If you qualify, you may receive tempol during treatment to help protect normal tissues and reduce toxicity.
La Jolla, CaliforniaAges 18 years+ - NCT07625657Recruiting
CLIKX System for Ear Tube Placement Surgery
This trial tests a new device called CLIKX that helps doctors place small tubes in the eardrum to treat ear fluid and hearing problems. The study will evaluate whether this device works safely and effectively for patients needing ear tube surgery.
Louisville, KentuckyAges 6 months+ - NCT07626437RecruitingPhase 3
Cold and Flu Symptom Relief Medicine Trial
This study tests a combination medicine containing pain reliever, caffeine, and allergy medication to help ease nasal congestion and other cold or flu symptoms. You'd take the medicine for a short period and report how well it works.
Belo Horizonte, Minas GeraisAges 18–60 - NCT07627971RecruitingPhase 1/Phase 2
Gene therapy for GJB2-related hearing loss in young children
This study tests an experimental gene therapy (SKY-GJB2) designed to treat hearing loss caused by mutations in the GJB2 gene. The therapy is given directly to children ages 9 months to 7 years who have significant bilateral hearing loss, and researchers will monitor safety and whether hearing improves.
Bethesda, MarylandAges 9 months–7 years - NCT07627087Recruiting
Balance and Navigation Skills After Vestibular Implant
This study tests how a vestibular implant—a small device that helps with balance—affects your ability to navigate spaces and your thinking skills. Researchers will give you cognitive tests before and after using the implant to see if it helps you move and think more clearly.
GenevaAges 18–80 - NCT07625462Recruiting
How hearing affects brain development in children
This research study looks at how hearing—whether typical or affected by hearing loss—shapes how children's brains grow and develop. Researchers will compare brain development in children with normal hearing, hearing aids, cochlear implants, and other hearing devices.
ShanghaiAges Up to 18 years - NCT07625423RecruitingPhase 1
Gene therapy injection for advanced head and neck cancer
This trial tests a new treatment where a specially designed virus carrying an anti-cancer gene is injected directly into tumors in the head and neck area. It's for patients whose cancer has come back or spread after prior chemotherapy and who cannot have surgery or radiation.
Chengdu, ChinaAges 18–65 - NCT07627399Recruiting
Best Care Practices for Stroke in Regular Hospital Units
This study tests whether following best-practice guidelines for stroke care in regular hospital units (rather than specialized stroke centers) helps patients recover better. Researchers will track how well patients do when they receive standardized stroke care protocols.
Antequera, MálagaAges 18 years+ - NCT06702085Recruiting
Lifestyle changes for older adults with tinnitus and metabolic syndrome
This study tests whether lifestyle changes (like diet and exercise) can help older adults who have both metabolic syndrome and chronic tinnitus (ringing in the ears). It is for people 65 and older with class 1 obesity and long-term ear ringing in both ears.
Dokki, Giza GovernorateAges 65–75 - NCT03745534Recruiting
Cochlear implant after Gamma Knife for vestibular schwannoma
This pilot study looks at how well cochlear implants work for hearing restoration in people who previously received Gamma Knife treatment for a tumor called vestibular schwannoma. It may help doctors understand what hearing results to expect after surgery.
Vienna, State of ViennaAges 18 years+ - NCT03745560Recruiting
Test hearing testing during surgery to guide cochlear implant decisions
This study uses a special hearing test done during surgery for vestibular schwannoma to help decide what hearing treatment you need afterward. It may help guide whether a cochlear implant is a good option for hearing rehabilitation.
Vienna, AustriaAges 18–99 - NCT06704256Recruiting
Using neck muscle scans to predict frailty before ENT surgery
This study looks at neck CT scans to see if muscle size can help predict frailty in people having ear, nose, or throat surgery. It may help doctors better prepare for your recovery.
New York, New YorkAges 18 years+ - NCT07620210Recruiting
Swallowing Therapy and Pressure Ball Training After Stroke
This study tests whether a swallowing therapy program (CTAR) combined with a pressure ball exercise helps older adults who had a stroke recover their ability to swallow safely. Many stroke survivors struggle with swallowing, which can lead to serious health problems, so this research aims to find better ways to help.
Tainan, Tainan CityAges 65–90 - NCT07618078Recruiting
Personalized Cancer Risk Assessment for Nasopharyngeal Cancer
This study helps doctors predict which patients with nasopharyngeal cancer (a cancer of the upper throat) will benefit most from additional chemotherapy after radiation treatment. It uses a special blood test and imaging to create a personalized risk score for each patient.
Beijing, Beijing MunicipalityAges 18–75 - NCT07620353Recruiting
Study of OROSEDAL for sore throat and mouth sores
This study observes how well OROSEDAL, a topical oral medication, works for sore throats and minor mouth ulcers or sores that have lasted less than 15 days. You'll be asked to track your pain relief while using the product your doctor prescribes.
Multiple LocationsAges 8 years+ - NCT06709690Recruiting
AI-powered PET/MR scanner for children with suspected cancer
This study tests a new, fast, and quiet AI-powered PET/MR scanner to take detailed pictures of children with suspected cancer. It aims to make the imaging experience easier and more comfortable for kids.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT06709092Recruiting
Testing Lupatadine for dust mite allergies
This study tests a new tablet (Lupatadine Fumarate) for people with nasal allergies caused by dust mites. It looks at how well the medicine works and what it does in the body.
Nanjing, JiangsuAges 18–65 - NCT07606547Recruiting
Swallowing Strength Training for Parkinson's Disease
This study tests whether a mouth and throat muscle-strengthening device called EMST helps people with Parkinson's disease who have difficulty swallowing. Stronger throat muscles may make swallowing safer and easier.
MünsterAges 18 years+ - NCT07611604Enrolling by invitation
Walking and Balance Changes in Long-Term Dizziness
This study measures how dizziness and balance problems affect the way people walk and move. Researchers compare people with chronic vestibular disease (long-term inner ear or balance nerve problems) to healthy volunteers to understand these differences better.
Istanbul, KüçükçekmeceAges 18–65 - NCT07608861Recruiting
Numbing Block to Reduce Pain Medicine During Nose Surgery
This study tests whether a special numbing injection in the upper jaw (bilateral maxillary block) helps reduce the amount of pain medication needed during septorhinoplasty—a surgery to reshape the nose and straighten the septum. The goal is to find ways to use less strong pain medication during surgery.
Yenimahalle, AnkaraAges 18–65 - NCT07604155Enrolling by invitation
Bone grafting for sinus lift in dental implants
This trial tests two ways to add bone in your upper jaw so dental implants can be placed. Researchers compare custom-made bone blocks to bone particles to see which works better for your bone growth.
TantaAges 20 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.