Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06641999Recruiting
Tinnitus implant study for adults with chronic tinnitus and hearing loss
This trial tests if a special implant can reduce tinnitus loudness in adults who have had chronic tinnitus for at least 6 months and have some hearing loss. You may qualify if your tinnitus is severe and not helped by standard treatments like hearing aids or therapy.
Edegem, BelgiumAges 18 years+ - NCT06636734RecruitingPhase 2
Lovastatin plus pembrolizumab for advanced head and neck cancer
This trial tests whether adding lovastatin (a cholesterol-lowering drug) to pembrolizumab (an immunotherapy) works better than pembrolizumab alone for head and neck cancer that has come back or spread. It's for people who haven't had immunotherapy before and aren't already on a statin.
Atlanta, GeorgiaAges 18 years+ - NCT06634823RecruitingEarly Phase 1
Steroid injection for chronic cough study
This study tests whether a steroid shot into the neck muscles can help people with a long-lasting, unexplained cough. It is for adults who have tried other treatments and still cough.
Charleston, South CarolinaAges 18 years+ - NCT06630013Recruiting
Ultrasound test for swallowing problems in patients with a tracheostomy
This study tests if a new ultrasound score can help diagnose swallowing disorders in patients who are difficult to wean from a breathing tube and have a tracheostomy. It may help doctors better assess swallowing without more invasive tests.
Beuvry, BeuvryAges 18 years+ - NCT06628414Recruiting
Brain stimulation study for tinnitus relief
This study tests whether a gentle brain stimulation technique called tDCS can help people with tinnitus. Volunteers will receive either real or fake stimulation to see if it reduces tinnitus symptoms.
NottinghamAges 18 years+ - NCT06623799Recruiting
Allergic rhinitis, help-seeking, and mental health study
This study looks at how people with allergic rhinitis (hay fever) seek help and how that relates to their mental health. Researchers hope to learn more about the connection between allergies, anxiety, and depression over time.
West Palm Beach, FloridaAges 4–100 - NCT06603935Enrolling by invitation
Digital medicine for allergic rhinitis management
This trial tests a digital platform to help manage allergic rhinitis (nasal allergies) and sinusitis. It's for adults whose symptoms are not well controlled despite treatment.
West Palm Beach, FloridaAges 18–65 - NCT06608017RecruitingPhase 2/Phase 3
Yupingfeng powder for allergic rhinitis
This trial tests whether Yupingfeng powder, a traditional Chinese herbal remedy, can help relieve allergic rhinitis symptoms like sneezing and a runny nose. It may be an option if your allergic rhinitis is linked to a deficiency in lung and spleen energy (a concept in Chinese medicine).
ShatinAges 18 years+ - NCT06600919Recruiting
Music therapy app for anxiety before ENT surgery
This study tests whether listening to calming music through a phone app before ENT surgery can help prevent anxiety. It is for adults who are scheduled for ear, nose, or throat surgery.
Saint-DenisAges 18 years+ - NCT06604494Recruiting
Spotting fistulas early after throat cancer surgery
This study tests whether measuring a substance called a "cytokine" in fluid draining from the surgery site can help find a fistula (an abnormal opening) early after throat cancer surgery. If fistulas are found quickly, they can be repaired sooner, which may help you recover better.
Clermont-FerrandAges 18 years+ - NCT06607146Recruiting
Computer training to improve hearing after cochlear implant
This study tests whether practicing listening exercises on a computer can help adults who just got a cochlear implant understand speech better and feel more satisfied with their hearing. If you are getting a cochlear implant at Mayo Clinic in Rochester, MN, you might be able to join.
Rochester, MinnesotaAges 18 years+ - NCT06614582Enrolling by invitation
Long-term nose tube study for children with weak muscle tone
This study looks at the long-term safety and effectiveness of a nose tube (nasopharyngeal airway) for children who have obstructive sleep apnea due to weak muscle tone. It's for children who already used this device in a previous study.
Ann Arbor, MichiganAges 3–23 - NCT06589804RecruitingPhase 3
Testing cetuximab plus pembrolizumab for advanced head and neck cancer
This trial tests whether adding cetuximab to the standard drug pembrolizumab works better for head and neck cancer that has spread or come back after treatment. It is for people whose cancer did not respond to platinum chemotherapy and whose tumors have a certain immune marker (PD-L1).
Little Rock, ArkansasAges 18 years+ - NCT06598319Recruiting
Pulsed field ablation for chronic rhinitis
This trial tests a new treatment that uses pulsed energy to target a nerve in the back of the nose to help with chronic rhinitis (long-term runny or stuffy nose). It is for people whose symptoms have not been controlled by nasal steroid sprays.
Colorado Springs, ColoradoAges 18–85 - NCT06592599RecruitingPhase 2
Drug combo for EBV-related nasopharyngeal cancer
This trial tests a combination of three drugs (gemcitabine, docetaxel, and toripalimab) as a first treatment for a type of nasopharyngeal cancer linked to the Epstein-Barr virus. The goal is to see if this combination helps shrink tumors before other treatments like radiation.
Palo Alto, CaliforniaAges 18 years+ - NCT06600295Recruiting
Taste changes and nutrition in new cancer patients
This study looks at how cancer and its treatments affect taste and nutrition. It aims to find ways to help patients maintain good nutrition during treatment.
DijonAges 18 years+ - NCT06599021Recruiting
Swallowing problems in older adults: a study
This study is looking at swallowing difficulties in people over 60. If you have trouble swallowing, you may be invited to try a simple exercise to help. The study first checks how common these problems are and how serious they are.
GothenburgAges 18 years+ - NCT06126627Recruiting
Brain and voice study for teachers with vocal fatigue
This study looks at how vocal fatigue affects the brain and voice in teachers. It uses MRI and voice tests to understand these changes.
BonnAges 21–39 - NCT06580210Recruiting
Seawater spray with essential oils for stuffy nose
This trial tests a seawater and essential oil spray to clear a stuffy nose caused by a cold, sinus infection or allergies. The spray is meant to help you breathe easier without strong medicines.
BayeuxAges 12 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06572423Recruiting
Personalized focused radiation for head and neck cancer
This trial tests a personalized, very precise radiation treatment (called PULS-Pal) for head and neck cancer that cannot be cured with standard therapies. It aims to shrink tumors and help with symptoms while limiting side effects.
Los Angeles, CaliforniaAges 18 years+ - NCT06567821RecruitingPhase 2/Phase 3
Using navigation to improve balloon sinus surgery accuracy
This trial tests whether using a navigation system during balloon sinus surgery makes the procedure more accurate for people with chronic sinusitis. It may help improve outcomes for those who have not had sinus surgery before.
Los Angeles, CaliforniaAges 18 years+ - NCT06580509RecruitingEarly Phase 1
Spray medicine for bleeding after tonsil removal in children
This study tests if a sprayed form of the medicine tranexamic acid (which helps blood clot) can stop bleeding after tonsillectomy in children. It is for children ages 2 to 17 who come to the emergency room with bleeding that starts more than a day after surgery.
San Antonio, TexasAges 2–17 - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.