Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT05360212Recruiting
Fitting a new cochlear implant sound processor using CT anatomy
This study tests a way to set up (fit) a new cochlear implant sound processor using CT scan anatomy. It may help people hear better by tailoring how electrodes are mapped to their inner ear shape.
Madrid, MadridAges 18 years+ - NCT05319678Recruiting
Music and voice testing in cochlear implant users
This study looks at how well cochlear implant users do musical and voice skills, including children and adults who use one or two implants. You might benefit by helping researchers understand how these skills develop and how devices work over time.
Madrid, MadridAges 6 years+ - NCT06682494Recruiting
Oral Cancer Awareness for African Americans
This study aims to raise awareness about oral cancer in the African American community. It will help researchers understand how to better communicate about prevention and early detection.
Richmond, VirginiaAges 18 years+ - NCT06683560Recruiting
3D-printed aligners for cleft lip and palate repair
This study tests whether custom 3D-printed aligners can help shape a baby's cleft lip, gum, and palate before surgery. It aims to make traditional molding treatment more precise and easier for families.
Cairo, AbbasyaAges Up to 1 month - NCT06688578Recruiting
Can a device that makes small noises improve balance and walking?
This study tests whether a device that plays small, random sounds (called stochastic noise) can help people feel steadier and walk better. It is for healthy adults of two age groups — those 60 and older, and those 21–59.
Baltimore, MarylandAges 21 years+ - NCT06682442Recruiting
Chemotherapy-guided radiation for EBV-related nasopharyngeal cancer
This trial tests whether the response to initial chemotherapy can guide the dose of radiation given to patients with Epstein-Barr virus (EBV)-associated nasopharyngeal cancer. The goal is to tailor treatment to reduce side effects while still being effective.
San Francisco, CaliforniaAges 18 years+ - NCT06688175Enrolling by invitationPhase 2
Combining IMRT and lobaplatin chemo for nasopharyngeal cancer
This trial tests whether combining a newer chemotherapy drug (lobaplatin) with standard radiation and chemotherapy is safe and effective for adults aged 65 to 80 with a certain type of nasopharyngeal cancer that hasn't spread to distant organs.
Xiamen, FujianAges 65–80 - NCT06691087Recruiting
Sound perception study for hearing aid users
This study looks at how people with hearing aids perceive sound. It compares results between hearing-impaired and normal-hearing participants to better understand hearing challenges in daily life.
ParisAges 60–75 - NCT06249919RecruitingPhase 1/Phase 2
Study of NS101 for sudden hearing loss
This trial tests an experimental medicine called NS101 for people who have had a sudden, severe hearing loss in one ear that did not get better with standard steroid treatment. The goal is to see if NS101 can help restore hearing better than steroids alone.
Bucheon-siAges 19–70 - NCT06177301RecruitingPhase 3
Comparing two drug combos for recurrent nasopharyngeal cancer
This study compares two combinations of drugs (tislelizumab plus either GX or GP) to see which works better for people with nasopharyngeal cancer that has returned or spread and has not been treated with systemic therapy before.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05482022Recruiting
Test speaking valve effects for people with tracheostomy and brain injury
This study checks whether a speaking valve changes breathing, swallowing, and voice in people who have a tracheostomy after a brain injury. It may help doctors find safer ways to improve communication and function for people who are in a minimal conscious or unresponsive state.
RaananaAges 18 years+ - NCT06676748RecruitingEarly Phase 1
Benzydamine gargle for sore throat after surgery
This trial tests whether a medicated mouthwash or gargle with benzydamine can help prevent a sore throat after surgery. It's for women having surgery with a type of breathing tube called a laryngeal mask airway.
SingaporeAges 21–80 - NCT06678100Recruiting
Swallowing study for adults with Alzheimer's
This study looks at swallowing problems in people with Alzheimer's disease compared to healthy older adults. If you have Alzheimer's, you'll have a swallowing test and your caregiver will answer questions about your daily life.
Nashville, TennesseeAges 60 years+ - NCT06676592Recruiting
3D technology to guide head and neck surgery
This trial tests whether 3D imaging can help surgeons better plan and perform head and neck operations. If you're scheduled for head and neck surgery and standard scans, this study may improve your surgical precision.
Basking Ridge, New JerseyAges 18 years+ - NCT06670521RecruitingPhase 2
Steroids for swallowing problems after breathing tube removal
This trial tests a steroid medication (corticosteroids) to reduce swelling in the voice box after a breathing tube is taken out. It may help improve swallowing and reduce the risk of food or drink going into the lungs.
Aurora, ColoradoAges 18 years+ - NCT06671184Recruiting
Predicting difficult thyroid surgery for less scarring
This trial looks at a tool doctors can use to predict if a certain type of thyroid surgery (through the mouth or under the chin) will be challenging. It helps people who want less visible scarring after their thyroid cancer surgery.
Shanghai, Shanghai MunicipalityAges Any age - NCT06680934Recruiting
CABP2 patient registry and natural history study
This study tracks people with hearing loss caused by changes in the CABP2 gene. It aims to understand how the condition develops over time.
GöttingenAges Any age - NCT06676098Recruiting
Best spot for a guided numbing shot for root canals
This study compares different injection spots for a new device that helps numb lower back teeth before root canal treatment. If you need a root canal on a lower molar or premolar, you may be able to help find the best spot for the numbing shot.
Boston, MassachusettsAges 18 years+ - NCT05884983Recruiting
Check if special CT and nose scope help screen nasopharyngeal cancer
This study tests whether combining a special CT scan with a nose/throat camera exam (nasopharyngeal endoscopy) can better find nasopharyngeal cancer early. You might benefit if the study shows this approach is accurate and safer for screening.
Zhongshan, GuangdongAges 30–69 - NCT06662058Recruiting
Remote hearing test for head and neck cancer patients on cisplatin or radiation
This study tests a remote hearing test to monitor hearing changes in patients with head and neck cancer getting cisplatin chemotherapy and/or radiation. The goal is to catch hearing loss early so treatment can be adjusted.
Atlanta, GeorgiaAges 18 years+ - NCT06663917Recruiting
Testing sound frequency settings for cochlear implant users with a hearing aid
This study tests different ways to set sound frequencies for people who have a cochlear implant and also use a hearing aid in the other ear. The goal is to find which setting helps you hear speech better.
New York, New YorkAges 18 years+ - NCT05847426Recruiting
Testing early hearing support using brain scans in babies
This study helps improve early hearing care by using a simple brain scan test (fNIRS) in babies with permanent hearing loss. It compares different early intervention approaches and aims to find better ways to support hearing development early on.
East Melbourne, VictoriaAges 24 years+ - NCT06651255Recruiting
Algorithm-guided care for bleeding in Von Willebrand disease
This trial tests whether a special algorithm can reduce repeat bleeding from the gut or nose in people with inherited Von Willebrand disease. If you have had serious nosebleeds or digestive bleeding, this study may help find a better way to manage your condition.
Lille, NordAges 18 years+ - NCT06088953Recruiting
Early hearing check for memory clinic patients
This study looks at how to detect hearing loss early in people with mild to moderate memory problems. It may help understand if hearing issues affect thinking skills.
LilleAges 50 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.