Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT07299578Recruiting
Sleep and Ménière's Disease Study
This study explores how sleep problems affect people with Ménière's disease. It involves a simple questionnaire to understand sleep patterns and their impact, which could help doctors provide better care.
StrasbourgAges 18 years+ - NCT07303023RecruitingPhase 3
Personalized neck radiation to prevent cancer spread
This trial tests whether a personalized radiation plan for the neck can prevent cancer from spreading in people with nasopharyngeal carcinoma. It's for those whose cancer hasn't spread beyond the head and neck area.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07304024RecruitingPhase 1/Phase 2
Testing a drug and sound therapy for age-related hearing difficulty
This trial tests whether a combination of an antihistamine (clemastine fumarate) and specially designed sounds can improve how the brain processes hearing in middle-aged adults with mild hearing loss. It might help if you have trouble understanding speech in noisy settings.
Aurora, ColoradoAges 45–65 - NCT07315945Recruiting
Allergic rhinitis severity survey in ENT visits
This study is testing a questionnaire to measure how severe your allergic rhinitis (hay fever) symptoms are during your ear, nose, and throat (ENT) checkups. If you are an adult with allergic rhinitis being seen at the ENT department, you may be asked to fill out the survey to help improve care.
StrasbourgAges 18 years+ - NCT07325539RecruitingPhase 2
Radiation and immunotherapy with chemo for nose and throat cancer
This trial tests combining low-dose radiation with an immunotherapy drug (toripalimab) and chemotherapy for people whose nose and throat cancer has come back or spread. The goal is to see if this combination works better than standard treatments.
Guangzhou, GuangdongAges 18–65 - NCT07326358Recruiting
AI help for doctors finding problems in nose and throat exams
This study uses artificial intelligence to help doctors better see and find issues during nose and throat camera exams. If you are getting this exam and agree to participate, your images may be checked by the AI system to see if it can improve detection.
ShanghaiAges 18 years+ - NCT07327216RecruitingPhase 3
Comparing two inhalations for mouth sores from cancer treatment
This trial tests if an inhaled medication called Sapylin can prevent or reduce severe mouth sores caused by chemoradiation, compared to a standard steroid inhalation. It is for people with advanced nasopharyngeal cancer who have not yet started treatment.
Zhanjiang, GuangdongAges 18–75 - NCT07328854RecruitingPhase 3
Lower versus standard radiation in stage II nasopharyngeal cancer
This trial compares a lower dose of radiation (40.2 Gy) to the standard dose (49.2 Gy) for patients with stage II nasopharyngeal carcinoma that has shrunk after initial chemoimmunotherapy. The goal is to see if the lower dose works just as well while potentially causing fewer side effects.
Hefei, AnhuiAges 18–75 - NCT07328841RecruitingPhase 3
Lower radiation dose study for advanced nasopharyngeal cancer
This trial compares a lower dose of radiation to the standard dose for people with advanced nasopharyngeal cancer that shrank after chemotherapy and immunotherapy. The goal is to see if a lower dose works just as well with fewer side effects.
Guangzhou, GuangdongAges 18–70 - NCT07332247RecruitingPhase 2
Immunotherapy plus chemo then immediate vs selective re-radiation for advanced recurrent NPC
This trial is for people with nasopharyngeal cancer that has come back in the same area. It tests whether giving additional radiation right after chemo plus immunotherapy works better than waiting to see if more radiation is needed later.
Guangzhou, GuangdongAges 18–70 - NCT07335874Recruiting
Hearing screening follow-up for congenital infection in newborns
This study checks if babies who fail their newborn hearing test might have a hidden infection from birth. It looks for cytomegalovirus (CMV), a common virus that can affect hearing, using a simple test.
StrasbourgAges birth–1 month - NCT07340515RecruitingPhase 3
Proton vs standard radiation for advanced nasopharyngeal cancer
This trial is testing whether a newer, more precise type of radiation (proton therapy) works better than standard radiation (IMRT) for people with advanced nasopharyngeal cancer. It also includes chemotherapy and immunotherapy to see if the combination can improve outcomes.
Jinan, ShandongAges 18–70 - NCT07267910Enrolling by invitation
Measuring inner ear function with weak electrical stimulation
This study uses a weak electrical current to test how well your inner ear balance system works. It may help people with certain inner ear conditions like vestibular schwannoma or vestibular neuritis.
HelsinkiAges 18–70 - NCT07348302RecruitingPhase 3
Allergy tablet for dust mite rhinitis and asthma
This trial tests an under-the-tongue tablet for people with dust mite allergies causing moderate to severe nasal symptoms or mild-to-moderate asthma. The goal is to see if it improves symptoms and can replace or reduce the need for allergy medicines.
Nueve de Julio, Buenos AiresAges 12–65 - NCT07356128Recruiting
How people with cochlear implants and hearing aids understand sound
This study tests how well children and adults can use sound from both ears when they have a cochlear implant in one ear and a hearing aid in the other (or a special device that combines both). It looks at how your brain makes sense of sounds to help improve hearing and speech understanding.
Oklahoma City, OklahomaAges 5 years+ - NCT07357558Recruiting
Reproductive health experiences in adults with PCD
This study is a conversation-based research project to understand how reproductive issues affect adults with Primary Ciliary Dyskinesia (PCD), a rare lung condition. By sharing your experiences, you can help doctors and researchers better support patients like you.
SouthamptonAges 18 years+ - NCT07359287Recruiting
Study on antibiotic use for respiratory infections
This study tests a program to help doctors prescribe antibiotics more carefully for common respiratory infections like colds, flu, bronchitis, and sinusitis. It may lead to better treatment for you.
CaenAges Any age - NCT07359586Recruiting
Laryngopharyngeal injury after breathing tube under anesthesia
This study looks at throat and voice box injuries that can happen after having a breathing tube during surgery. It may help doctors understand why some people experience hoarseness, sore throat, cough, or choking after non-ear-nose-throat operations.
Hangzhou, ZhejiangAges Any age - NCT07362979RecruitingPhase 2
Toripalimab with chemo for advanced nasopharyngeal cancer
This trial tests adding toripalimab (an immunotherapy) to two different platinum-based chemotherapy regimens as initial treatment for locally advanced nasopharyngeal carcinoma. The goal is to see if this combination is more effective than standard treatment.
Dongguan, GuangdongAges 18–70 - NCT07364747RecruitingPhase 2
Does acetylcysteine protect hearing during cisplatin chemo?
This trial tests if taking N-acetylcysteine (NAC) can help prevent hearing loss caused by high-dose cisplatin chemotherapy. If you're getting cisplatin and are between 18 and 70, you may be able to join.
Bangkok, BangkoknoiAges 18–70 - NCT07364955Recruiting
Vestibular rehab for acoustic neuroma patients
This trial tests whether a specific exercise program can help with balance and dizziness in people with a benign tumor on the hearing and balance nerve (acoustic neuroma). It may be a good fit if you have a medium to large tumor on one side.
Badalona, BarcelonaAges 18–70 - NCT07379775Recruiting
Testing AAR for nasal obstruction surgery decisions
This trial tests whether a simple device that measures your breathing (AAR) is reliable enough to help doctors decide if surgery is needed for nasal obstruction. It looks at patients who already plan to have surgery to see if this test matches what the surgeon finds.
Draguignan, VarAges 18 years+ - NCT07380269Recruiting
Long-term study of cochlear implant outcomes
This study follows people who get a cochlear implant – a device that helps restore hearing. It tracks how well you hear over time and checks for any long-term benefits or problems.
ShanghaiAges Any age - NCT07383493Recruiting
Treatments for cold and sinus infections
This study tests treatments for the common cold, sinus pain, or sore throat caused by a virus. It compares different options to see which works best for reducing symptoms like runny nose, congestion, and cough.
Clermont-FerrandAges 18–70
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.