Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,273 recruiting studies in this area right now.
By phase
- Not applicable891
- Phase 2156
- Phase 3103
- Phase 148
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma74
- Dysphagia67
- Hearing Loss61
- Tinnitus29
- Head and Neck Cancer24
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,273 total
- NCT03704207Recruiting
Testing a diagnostic workup to guide care for PCD
This study checks whether using “PCD diagnostics” helps clinicians make better care decisions for people being evaluated for PCD. You might be able to join if you’re referred for PCD diagnosis and can complete the study steps.
Nashville, TennesseeAges 1 year+ - NCT03502590Recruiting
Test of a throat breathing device for people with neck radiation
This study tests how well a specific airway device works during general anesthesia for people who had radiation therapy to the neck. It may help improve safety and comfort during planned surgeries.
LivingstonAges 18 years+ - NCT03429036Recruiting
Collecting head and neck tissue samples for research
This study collects tissue and fluid samples from people with head and neck disorders to help researchers learn more about these conditions. By donating leftover samples from your regular medical care, you can help advance research without extra procedures.
Washington D.C., District of ColumbiaAges 3–120 - NCT03306082Enrolling by invitation
Test whether guided programming improves cochlear implant settings
This study checks whether an imaging-guided method can help tune your cochlear implant to improve hearing performance compared with the usual programming approach. It mainly looks at adults who already have a cochlear implant and have shown expected improvements with standard setup.
Nashville, TennesseeAges 18–90 - NCT03439865RecruitingEarly Phase 1
Ivacaftor for sinus problems linked to faulty CFTR
This early-phase study tests whether ivacaftor can improve chronic sinus disease caused by problems with a specific body channel called CFTR. It may help some people whose sinus imaging, cultures, and prior sinus surgery match the study’s criteria.
Birmingham, AlabamaAges 18 years+ - NCT03511807Recruiting
Tests sound and mild electrical stimulation for tinnitus relief
This study tests whether adding sound and/or mild electrical stimulation can reduce tinnitus (ringing or other noises in the ear). It is looking for adults who have had tinnitus for at least 6 months and can complete questionnaires about what they feel.
Irvine, CaliforniaAges 18 years+ - NCT03050268Recruiting
Study of childhood cancer risk in families
This study looks at inherited (family) risk for childhood cancers, including families with early cancers or known cancer risk conditions. It may help researchers understand why some children get cancer and improve future risk detection and care.
Memphis, TennesseeAges Any age - NCT03101722Enrolling by invitation
Huperzine A for hearing loss, tinnitus, and mild memory issues
This trial tests whether huperzine A can improve hearing-related symptoms along with tinnitus (ringing) and mild cognitive (memory/thinking) problems. If you have mild-to-moderate hearing loss plus bothersome constant tinnitus and some cognitive decline, this study may help researchers see if the treatment makes a difference.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT02734537RecruitingPhase 2
Radiation with or without cisplatin after head and neck surgery
This trial studies whether adding cisplatin (a chemotherapy medicine) to radiation therapy helps people with stage III–IVA squamous cell cancer of the head and neck after they’ve had surgery. It’s meant to lower the risk of the cancer coming back.
Birmingham, AlabamaAges 18 years+ - NCT03011541Recruiting
Stem cell treatment for damaged retina or optic nerve
This study looks at stem-cell treatment to help vision in adults whose retina or optic nerve damage is not expected to improve on its own. You may be a candidate if your eye exam shows documented, stable or slowly changing damage and you can safely complete follow-up eye visits.
Westport, ConnecticutAges 18 years+ - NCT03010150Recruiting
Blood tests and swallowing exercise check-ins for head and neck cancer
This study looks at whether giving swallowing exercises and checking in with questionnaires can help people with metastatic (spreading to neck lymph nodes) head and neck cancers do the exercises correctly. It also uses blood tests to better understand adherence and progress over time.
Houston, TexasAges 18 years+ - NCT02818400Recruiting
Face transplant evaluation for severe facial tissue loss
This trial studies face tissue transplantation for people who have lost facial tissue that cannot be fixed with standard surgical methods. It focuses on how the face looks and works after surgery, and it may help restore function and appearance when other options aren’t enough.
AmiensAges 18–50 - NCT02960737Recruiting
Training for swallowing problems after stroke
This trial studies whether a specific oral training program can improve swallowing after a stroke. It’s mainly for people whose swallowing trouble has lasted for several weeks after their stroke.
UmeåAges 18 years+ - NCT02193542Recruiting
Study of breathing tube and epidural difficulty in childbirth
This study observes how often pregnant people have a difficult airway (trouble placing a breathing tube) or difficult neuraxial placement (like an epidural) during childbirth. It helps doctors improve safe delivery care.
Boston, MassachusettsAges Any age - NCT02310399Recruiting
Auditory brainstem implant for children without cochleae or hearing nerves
This study looks at whether an auditory brainstem implant (ABI) can help children hear sounds and develop listening/communication skills when the usual inner-ear hearing structures or hearing nerves are missing or not working. It may help some children who cannot benefit from a cochlear implant, but spoken language may not be the main outcome.
New York, New YorkAges 1.5 years–21 years - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age - NCT01365169Recruiting
How activity level and daily function relate to cancer survival
This study looks at how physical activity (movement during the day) and a clinician-rated “day-to-day function” score relate to overall survival in people with certain cancers. It may help doctors understand who benefits most from activity-focused care and better monitoring.
Houston, TexasAges 18 years+ - NCT02128906RecruitingPhase 2
Radiation plus chemo choices for throat cancer, using a tumor marker
This trial compares two treatment combinations given with radiation for certain cancers of the throat. It also uses a lab test on the tumor (ERCC1) to help choose and study which treatment works better.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT02038166Recruiting
Measuring nasal function in adults with chronic sinus symptoms
This study tests a specialized way of measuring how your nasal lining responds in people with chronic rhinosinusitis (long-lasting sinus inflammation). The goal is to see whether the nasal measurement is usable and safe, and to help better understand chronic sinus disease.
Birmingham, AlabamaAges 18 years+ - NCT01473784Recruiting
Robot-assisted mouth and throat surgery for head and neck tumors
This trial studies using a robot-assisted operation through the mouth to diagnose or treat certain non-cancer (benign) and cancer (malignant) tumors in the head and neck. It may help some people avoid more invasive surgery by using an approach that reaches the throat and voice box area through the mouth.
Columbus, OhioAges 18 years+ - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT01694940Recruiting
Mitochondrial disease registry and sample collection study
This trial builds a large database and collection of lab results, and possibly tissue samples, from people with suspected or diagnosed mitochondrial conditions. It helps researchers learn more about these disorders and mitochondrial DNA changes, which may improve future diagnosis and treatments.
San Diego, CaliforniaAges Any age - NCT00807482Recruiting
Study of lung disease causes in primary ciliary dyskinesia
This study looks at how primary ciliary dyskinesia (PCD—a lifelong problem with tiny lung “sweepers”) affects the lungs. You may be able to join if you strongly seem to have PCD based on symptoms, or if you’re a healthy person with a close family member who has confirmed PCD.
Chapel Hill, North CarolinaAges Any age - NCT00598351Recruiting
Study tracks changes in NF2 using repeated brain scans
This study follows people with neurofibromatosis type 2 (NF2) over time to learn how the condition changes, using repeat MRI scans. The information may help researchers understand disease patterns and improve future treatments.
Bethesda, MarylandAges 8–75
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,273 recruiting otolaryngology studies from the U.S. registry right now, out of 2,079 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.