Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT07636590Recruiting
Study of vision changes in limbal stem cell deficiency
This observational study follows patients with limbal stem cell deficiency (a condition affecting cells at the edge of the cornea that help maintain healthy eye surface) to understand how their vision changes over time. Researchers will track your eye health without giving you new treatment.
Carmel, IndianaAges 12–99 - NCT06566339Recruiting
Robotic eye scan for emergency room patients
This study tests a new robotic device that uses light scans (OCT) to look at the front part of your eye. It may help find problems like redness or a foreign body without needing traditional exams.
Durham, North CarolinaAges 18 years+ - NCT04735263RecruitingTeam says not enrollingPhase 2
Testing dark vision changes as a statin response signal
This Phase 2 study looks at whether changes in night/dark adaptation can show early whether high-dose atorvastatin (a statin) is helping intermediate age-related macular degeneration (AMD). If you fit, you may help researchers find an earlier way to tell who is responding.
Boston, MassachusettsAges 50–85 - NCT07075159Recruiting
Hydrocolloid dressings for eye area surgery recovery
This trial tests if a special type of bandage (hydrocolloid dressing) helps heal wounds after eye or face surgery. The goal is to see if it improves healing and comfort.
Lexington, KentuckyAges 18–100 - NCT06976034Recruiting
High-resolution eye camera study for eye conditions
This study uses a new type of eye camera to take very detailed pictures of the front of the eye (cornea, lens, and nearby areas). It is for people with certain eye conditions or for healthy volunteers.
ParisAges 18–80 - NCT06859216Recruiting
Testing AI-made plain language summaries for eye clinic notes
This study tests whether using artificial intelligence (AI) to create easy-to-read summaries of your eye doctor's notes helps people better understand their eye care. If you are an English-speaking patient at the Jules Stein Eye Institute, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT06841250Enrolling by invitation
Early eye changes after first injection for diabetic macular edema
This study looks at how the eyes of people with diabetes-related swelling in the retina change after their very first anti-VEGF injection. By measuring early changes in OCT scans, doctors hope to learn more about how well the treatment works and how to predict outcomes.
SohagAges Any age - NCT06859515Recruiting
Long-term follow-up for wet AMD treatment
This study checks on the long-term safety and effects of a one-time treatment (EXG102-031) for wet age-related macular degeneration. It is only for people who already received that treatment in a previous study.
BeijingAges 50 years+ - NCT06857032Enrolling by invitation
Long-term safety of LASIK-Xtra vs standard LASIK
This study checks the long-term safety and effectiveness of a special type of laser eye surgery called LASIK-Xtra, compared to the standard LASIK procedure. It is meant for people who were in an earlier study of these surgeries from 2014 to 2018.
Frankfurt am Main, HesseAges 18 years+ - NCT06817265RecruitingPhase 3
TNTL for diabetic eye disease (non-proliferative)
This study tests if a drug called TNTL can help people with type 2 diabetes who have early-stage diabetic eye disease (non-proliferative diabetic retinopathy) without severe vision loss. It aims to see if the treatment is safe and effective in slowing or improving the condition.
Xuancheng, AnhuiAges 18–75 - NCT06755190Recruiting
AI help for eye disease decisions
This trial uses artificial intelligence to help doctors make better decisions about eye disease. It analyzes your medical records and images to see how AI can improve care and track disease.
Zhuhai, GuangdongAges Any age - NCT06704503Recruiting
Eye structure changes with different focus
This study looks at how the front part of the eye and the lens change shape when you focus on things at different distances. It may help people who have astigmatism and good vision to understand how their eyes work.
Hangzhou, ZhejiangAges 20–80 - NCT06756009Recruiting
Eye scans to check liver disease and transplant outlook
This study uses advanced eye scans to see if your eyes can give clues about your chronic liver disease and how well you might do after a liver transplant. If you have advanced liver disease or cirrhosis, and are maybe waiting for a transplant, you may join.
Guangzhou, GuangdongAges 18 years+ - NCT06752486RecruitingPhase 1
Gabapentin for pain after laser eye surgery
This study tests if a medicine called gabapentin can safely reduce pain after a type of laser eye surgery called surface ablation. It's looking for adults with stable vision who are generally healthy and have not had previous eye procedures.
GizaAges 18–65 - NCT06694259Recruiting
Laser vs. freezing for retinal detachment repair
This trial compares two methods (laser or freezing) to seal tears in the retina after a procedure to reattach it. It may help people with a specific type of retinal detachment where the tear is in the upper part of the eye.
SplitAges 18 years+ - NCT06613555Recruiting
Eye blood vessel scan study for systemic disease
This study uses an advanced eye scan (OCT-A) to look at tiny blood vessels in the back of the eye. It compares people with systemic blood vessel conditions (like high blood pressure or inflammatory disease) to healthy volunteers, to see if the eye scan can help predict or understand these diseases.
DijonAges 18 years+ - NCT06644196Recruiting
Building an eye image database with new laser technology
This study uses a special laser to take detailed images of the eye. It aims to create a database that could help doctors better understand and diagnose eye conditions like glaucoma, macular degeneration, and retinal diseases.
ParisAges 18 years+ - NCT06600945Recruiting
Comparing two muscle relaxants for cataract surgery
This trial tests if adding magnesium sulfate to a standard muscle relaxant (atracurium) improves local anesthesia for cataract surgery. It may help patients stay comfortable during the procedure.
MinyaAges 20–80 - NCT06530264Recruiting
Comparing methods for tear duct surgery
This trial compares different ways to manage the flap during external dacryocystorhinostomy (a surgery to clear blocked tear ducts). It may help if you have a blocked tear duct, a tear sac infection or a tear sac cyst or fistula.
MinyaAges 18–75 - NCT06555367Recruiting
Scleral lenses for eye surface diseases
This trial tests whether special contact lenses called scleral lenses can help people with certain eye problems, such as an irregularly shaped cornea after surgery or injury. The lenses may improve vision and comfort for those with these conditions.
Hangzhou, ZhejiangAges 18 years+ - NCT06583811Recruiting
Sedatives for staying still during long eye surgery
This trial tests two sedative medications, remifentanil and remimazolam, to see which one better keeps patients still during long eye surgeries. It aims to make surgery safer and more comfortable for you.
CairoAges 40–50 - NCT06450392RecruitingPhase 4
Tranexamic acid for less swelling and bruising after eye socket surgery
This study tests whether giving tranexamic acid (a medicine that helps blood clot) locally or through an IV can reduce swelling and bruising after eye socket surgery.
The Bronx, New YorkAges 18 years+ - NCT06412224RecruitingEarly Phase 1
Testing a new drug for diabetic eye disease after vitrectomy
This trial tests a new medicine, RRG001, given after vitrectomy surgery for severe diabetic eye disease. It aims to see if the drug is safe and helps prevent vision loss.
TianjinAges 20–80 - NCT06031727RecruitingEarly Phase 1
CRISPR gene therapy for wet age-related macular degeneration
This trial tests a new CRISPR-based treatment for wet age-related macular degeneration (AMD). It aims to stop vision loss by targeting the cause of abnormal blood vessel growth in the eye. This study is for people who have already tried anti-VEGF injections but might not be responding well enough.
Shanghai, Shanghai MunicipalityAges 50–80
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.