Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT05371977Recruiting
Deep sclerectomy or trabeculectomy for normal tension glaucoma
This trial compares two types of glaucoma surgery to lower pressure and protect vision in people with normal tension glaucoma. If your glaucoma is not well controlled on drops, you may be considered to help find which surgery works better and more safely.
HelsinkiAges 55–100 - NCT06359548Recruiting
Repositioning the retina's inner layer for macular hole repair
This study tests a surgery for people with a small macular hole (a break in the retina's center). The surgeon repositions the inner layer of the retina to help the hole heal. It may be an option if you are between 50 and 80 and have not had eye surgery before.
ShanghaiAges 50–90 - NCT06359795Recruiting
PET Scan for Thyroid Eye Disease Activity
This study uses a special PET/CT scan (with a tracer called 18F-AlF-FAPI) to see how active your thyroid eye disease is. It may help doctors better understand and manage the condition.
Beijing, Beijing MunicipalityAges 18–80 - NCT06364878Recruiting
Non-invasive diagnosis for eye infections
This study tests a new, non-invasive (no needles or surgery) way to diagnose a type of eye infection called microbial keratitis. It may help find the cause faster so you get the right treatment sooner.
ArendalAges 18 years+ - NCT05828251Recruiting
Treating a fresh macular hole sooner or later
This study looks at how to manage a full-thickness macular hole that started recently, comparing different timing (“subacute” care) to see which approach helps vision best. You may be considered if your hole is small and new, and you can follow required eye positioning after treatment.
Glostrup Municipality, CopenhagenAges 18 years+ - NCT06367530Recruiting
Trilateral retinoblastoma: incidence and outcomes
This study looks at how often trilateral retinoblastoma (a rare form that affects the brain as well as the eye) happens and what the outcomes are. It may help doctors better understand this condition.
Amsterdam, North HollandAges Any age - NCT02014389Recruiting
Testing pupil measurements with colored light in eye exams
This study checks how well a device can measure how your pupils respond to colored light. It may help improve eye testing, especially when monitoring certain vision and nerve conditions.
Tel LitwinskyAges 18–80 - NCT05405868RecruitingPhase 3
Nicotinamide for early to moderate open-angle glaucoma
This trial tests whether nicotinamide (a form of vitamin B3) can slow vision changes from open-angle glaucoma. It compares nicotinamide versus a placebo (inactive pill) in adults with early to moderate disease.
Belfast, Northern IrelandAges 18 years+ - NCT06412224RecruitingEarly Phase 1
Testing a new drug for diabetic eye disease after vitrectomy
This trial tests a new medicine, RRG001, given after vitrectomy surgery for severe diabetic eye disease. It aims to see if the drug is safe and helps prevent vision loss.
TianjinAges 20–80 - NCT06410833RecruitingPhase 4
Combination therapy for resistant Sjögren's in children
This trial tests a combination of two medicines, rituximab then belimumab, for children and teens with Sjögren's syndrome that hasn't improved with other treatments. The goal is to see if this two-step approach can better control symptoms like joint pain, skin rashes, and blood problems.
Beijing, Beijing MunicipalityAges 5–18 - NCT06417502Recruiting
China pediatric rheumatic disease registry study
This study collects information from children with rheumatic and immune system diseases in China to better understand these conditions. By participating, you help researchers learn more about how to diagnose and treat these diseases.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT06370104Recruiting
Online therapy for recent suicidal thoughts or behavior
This study tests a remote therapy program for people who have had suicidal thoughts or behaviors in the past month. It aims to provide timely support without needing to see a therapist in person.
Amsterdam, South HollandAges 16 years+ - NCT07851532Recruiting
Vision screening for farsightedness in kindergarten children
This study checks kindergarten children for hyperopia (farsightedness) to find those who may need glasses or other vision help. It aims to catch vision problems early so they can be treated.
BeijingAges Any age - NCT06429969Recruiting
Vitreous fluid chemicals in eye diseases
This study looks at the chemicals in the fluid inside your eye (vitreous) using a special scan. It aims to find patterns that might help doctors understand certain eye diseases better.
Wuhan, HubeiAges 40–90 - NCT07844148RecruitingPhase 3
Comparing two eye injections for wet age-related macular degeneration
This study compares two eye injection treatments for wet age-related macular degeneration (AMD), a condition that causes vision loss. The trial aims to see if the new drug GNR-139 works as well as the standard treatment Eylea.
Cheboksary, CheboksaryAges 50 years+ - NCT07848555Recruiting
Skin and eye tolerance study for a cosmetic product
This study tests a cosmetic product to see if it is gentle on the skin and eyes and if it causes blackheads or pimples. It may be a good option if you have oily, acne-prone skin and are looking for a product that is unlikely to irritate.
Osasco, São PauloAges 18–45 - NCT07844317Recruiting
AI eye check for diabetic retinopathy
This trial tests an AI system that automatically checks eye photos for signs of diabetic retinopathy, a diabetes complication that can harm vision. If you have diabetes, this study may help detect the condition earlier and prevent vision loss.
Jacksonville, FloridaAges 22 years+ - NCT07842536Recruiting
Goji berry extract for dry eye disease
This trial tests whether a supplement made from goji berries can help people with dry eye disease. Dry eyes happen when your eyes do not make enough tears or the tears evaporate too quickly, which can cause discomfort and blurry vision. The study aims to see if this natural supplement improves symptoms and signs of dry eye.
Hong Kong, Hong KongAges 18–60 - NCT07847073RecruitingPhase 4
Comparing eye drops for glaucoma and their effect on the optic nerve
This trial tests two eye drops—Rhopressa (netarsudil) and timolol—at lowering eye pressure in people with open-angle glaucoma. The study uses a special camera to see if treatment helps protect the nerve cells in the back of the eye.
Bloomington, IndianaAges 18 years+ - NCT07843849RecruitingPhase 4
Steroid treatment for diabetic macular edema
This study tests whether a steroid medication can help reduce swelling in the back of the eye caused by diabetic macular edema, a complication of type 2 diabetes. If you qualify, you may receive this treatment to potentially improve your vision.
Nashville, TennesseeAges 18 years+ - NCT07844655Recruiting
Wellness study for PSP and CBD
This study explores how wellness activities, like exercise, might help people with progressive supranuclear palsy (PSP) or corticobasal degeneration (CBD). Participation involves filling out electronic questionnaires and engaging in exercise, with the goal of improving quality of life.
Vancouver, British ColumbiaAges 19 years+ - NCT07843381Recruiting
Testing a new drug for Sjögren's syndrome with lung disease
This clinical trial tests a new drug called telitacicept for people who have both Sjögren's syndrome and interstitial lung disease. The drug aims to reduce the immune system's attack on your body and may help improve lung symptoms.
BeijingAges 18–70 - NCT06451172RecruitingEarly Phase 1
New antibiotic eye drops for drug-resistant eye infections
This trial tests a new type of antibiotic eye drop for people with serious eye infections that don't respond to standard antibiotics. It aims to see if these drops can safely treat the infection and help improve vision.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05516004RecruitingPhase 2
Cornea strengthening treatment study for thinning corneas
This Phase 2 study tests whether a procedure called PXL‑Platinum 330 can safely and effectively strengthen corneas that are thinning (such as keratoconus or related conditions). It aims to see if the treatment can help stabilize or improve the cornea’s shape while keeping side effects low.
Boca Raton, FloridaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.