Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07841470RecruitingPhase 2/Phase 3
Corneal crosslinking for progressive keratoconus or corneal ectasia
This study tests a procedure called corneal crosslinking to slow or stop the progression of keratoconus or corneal ectasia. It might help keep your cornea stable and prevent further vision loss.
Indianapolis, IndianaAges 10–90 - NCT07836452RecruitingPhase 1
Study of a new drug for healthy people and those with Stargardt disease
This study tests a new drug called CITY-RBP4 in healthy volunteers and in people with Stargardt disease (STGD1), a genetic condition that causes vision loss. The goal is to see if the drug is safe and how it affects the body, which may help guide future treatments for Stargardt disease.
Melbourne, VictoriaAges 12–45 - NCT07835607Recruiting
Comparing pet scans and mri for thyroid eye disease
This study compares two PET imaging methods and an MRI to see which better shows inflammation in thyroid eye disease. Participation may help improve detection and monitoring of this condition.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07838181Recruiting
Virtual reality test for visual distortions
This study tests whether a virtual reality (VR) tool can help detect and measure visual distortions (like wavy or bent lines) in people with certain eye conditions. It may offer a more precise way to monitor these changes compared to traditional tests.
New York, New YorkAges 18 years+ - NCT07840209Recruiting
Hand-eye coordination with study contact lenses for baseball and softball players
This study tests whether special multifocal contact lenses, called MiSight, affect hand-eye coordination and sports vision compared to your regular contact lenses. If you play baseball or softball at a high school level or higher, this study may show if these lenses help or change your game.
Columbus, OhioAges 18–38 - NCT07832552Enrolling by invitationPhase 3
Eye drop treatment for pain and swelling after cataract surgery
This study tests a medication given as an injection during cataract surgery to prevent eye pain and swelling. It aims to see if it helps you recover more comfortably.
Kansas City, MissouriAges 18 years+ - NCT07832305Recruiting
Blood pressure targets and eye blood flow during nose surgery
This study looks at how different blood pressure targets during nose surgery affect blood flow to the eye and the optic nerve. It aims to find the safest way to protect eye health during anesthesia.
ÇorumAges 18 years+ - NCT07827040Recruiting
Vision rehabilitation for improving quality of life in low vision adults
This programme helps adults with low vision (not fully correctable by glasses) improve their daily life through a multi-disciplinary team approach. It may help you function better at home and in the community.
Kowloon, Hung HomAges 18–80 - NCT07831876RecruitingPhase 1
Ear nerve stimulation for eye inflammation
This study tests whether gently stimulating a nerve in the ear can help reduce swelling or irritation in the eyes. It may offer a new drug-free way to treat certain types of eye inflammation.
Basking Ridge, New JerseyAges 18 years+ - NCT06338735Recruiting
High-frequency ultrasound for Sjögren's diagnosis
This study uses a special, very high-frequency ultrasound to take detailed images of the small glands that can be affected in Sjögren's syndrome. The goal is to see if this new ultrasound technique can help doctors diagnose Sjögren's more accurately.
PisaAges 18 years+ - NCT07819305Recruiting
Comfort and vision of new daily-wear contact lenses
This study tests a new type of daily-wear contact lens for people with nearsightedness. It will check how comfortable and effective the lenses are for your eyes. If you already wear soft contacts regularly, you may be able to join.
Jacksonville, FloridaAges 18–39 - NCT07825337Recruiting
Futuristic headset to help surgeons see during eye surgery
This study tests whether a futuristic headset that projects digital information can help surgeons see better during eye surgery. You may be able to participate if you are having a standard eye procedure and have no other eye problems that could make surgery riskier.
Brentwood, New YorkAges 18–90 - NCT07819552Recruiting
Virtual reality therapy for adult lazy eye
This trial tests a virtual reality (VR) therapy for adults with lazy eye (amblyopia) caused by a difference in prescription between the two eyes. It uses special glasses to train your eyes to work together, which may improve vision.
Coimbra, Coimbra DistrictAges 18–40 - NCT07818239Enrolling by invitation
How diet affects eye blood vessels
This study looks at how different foods and drinks affect the blood vessels in your eyes. By taking pictures of your retina (the back of the eye) after certain meals, researchers hope to learn more about diet and eye health.
ViennaAges 18 years+ - NCT05592717Recruiting
YUTIQ implant for chronic non-infectious eye inflammation
This trial tests whether a small steroid implant placed inside the eye (YUTIQ 0.18 mg) can control chronic non-infectious uveitis. It may help reduce active inflammation and prevent flare-ups, as long as you’ve had recent signs of active disease and can follow the medication and eye-visit rules.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07809516Recruiting
Pedal pump for leg swelling
This trial tests a device called a 'pedal pump' that helps move fluid out of your legs to reduce swelling. It may help if you have fluid buildup from conditions like heart failure or kidney disease.
Tulsa, OklahomaAges 18 years+ - NCT07812090RecruitingPhase 2
Oral medication for diabetic macular edema
This study tests an oral medication that may reduce swelling in the retina caused by diabetes. If you have diabetic macular edema affecting your central vision, this trial could help you preserve or improve your sight.
McAllen, TexasAges 18–75 - NCT07816692Recruiting
iDose implant for open-angle glaucoma
This study tests a tiny implant, called iDose, that is placed in the eye during a short office procedure to help lower eye pressure in people with open-angle glaucoma or high pressure in the eye (ocular hypertension). It may offer a way to manage pressure without daily eye drops.
Austin, TexasAges 18 years+ - NCT07811726RecruitingPhase 2
Eye drops for wet age-related macular degeneration
This trial tests a new eye drop called NT-101 for people with wet age-related macular degeneration (AMD), a leading cause of vision loss. The goal is to see if the drops can improve vision and reduce fluid in the eye, possibly as a less invasive alternative to injections.
Bonita Springs, FloridaAges 50 years+ - NCT06492863RecruitingPhase 1/Phase 2
Gene therapy (FT-003) for wet AMD
This trial tests a new gene therapy, FT-003, for people with wet AMD. It aims to see if a single treatment can help stop vision loss and may reduce the need for frequent eye injections.
Tianjin, Tianjin,ChinaAges 50–80 - NCT07813598Recruiting
Eye scan study for children with uveitis
This study tests a new, quick eye scan to help doctors spot signs of uveitis (inflammation inside the eye) in children with JIA (a type of arthritis that can affect the eyes). The goal is to make eye exams easier and more accurate for children.
Sheffield, South YorkshireAges 2–16 - NCT07816887Recruiting
Eye gel changes after cataract surgery
This study looks at how the gel-like fluid inside the eye changes after cataract surgery using special eye scans. It may help doctors understand more about eye health after this common procedure.
Créteil, ParisAges 50 years+ - NCT07816224RecruitingPhase 2
Low-dose atropine eye drops for excessive tearing
This study tests whether low-dose atropine eye drops, given nightly for 7 days, can reduce excessive tearing (epiphora) in adults. If you have bothersome tearing not caused by dry eyes, this treatment might offer relief.
Houston, TexasAges 18 years+ - NCT06492876RecruitingPhase 1/Phase 2
Gene therapy trial for diabetic macular edema (DME)
This trial tests a gene therapy for diabetic macular edema (DME), a condition where fluid builds up in the central part of the eye's retina. It aims to improve vision and reduce the need for frequent eye injections.
Tianjin, Tianjin,ChinaAges 18–74
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.