Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT05858983RecruitingPhase 1/Phase 2
Gene therapy for certain RPE65 inherited eye conditions
This early-stage trial tests a gene therapy aimed at treating inherited retinal dystrophy caused by changes in the RPE65 gene on both copies. It may help slow vision loss or improve eye function, but the study is mainly about safety and learning how the treatment works.
Beijing, Beijing MunicipalityAges 8–45 - NCT05554133Recruiting
Optical guidance study for oral biopsy planning
This study tests a “precision optical” method to help guide an oral biopsy in people with abnormal or potentially cancerous mouth spots. It may help clinicians target the right area to sample, making diagnosis more accurate.
Houston, TexasAges 18 years+ - NCT05635812Recruiting
Brain and eye tests of facial emotion recognition in autism
This study uses brain and eye measurements to understand how people recognize facial expressions, including in autism and related conditions. It may help researchers find markers that better explain autism-related symptoms and differences in processing emotions.
DijonAges 7–50 - NCT04833491Recruiting
Eye measurements before cataract surgery and vision quality after
This study uses very specific eye measurements done before cataract surgery to see how they relate to the clarity of vision after surgery. It may help surgeons choose the best surgical approach and improve visual outcomes.
HangzhouAges 2–90 - NCT04959838Recruiting
Study of job stress in eye doctors and trainees
This study looks at job stress among ophthalmologists (eye doctors) and ophthalmology residents. It may help improve working conditions and support for people in eye care.
Clermont-FerrandAges 18–65 - NCT05037370Recruiting
Compare two eye laser procedures for vision correction
This study compares two types of laser surgery for vision problems (PRK versus another approach called “WFO ablation”) to see which works better for clear sight. You may be a candidate if you meet specific eye measurements and can return for follow-up visits.
San Antonio, TexasAges 21–50 - NCT05072262RecruitingPhase 4
Topical anti-inflammatory eye drops after corneal transplant
This study tests whether anti-inflammatory eye drops (nepafenac, an NSAID) can help reduce swelling in the macula (the sharp-vision part of the eye) after certain cornea transplant surgeries. It compares outcomes in adults having DSAEK or DMEK who can safely use the study drops.
OsloAges 18 years+ - NCT04704648Recruiting
Surgery for a one-eye surface tumor in people with HIV
This study looks at whether removing a suspected pre-cancer/cancer growth on the surface of the eye can be done safely in people living with HIV. It is a feasibility (safety and practical) study, helping doctors refine the best surgical approach and follow-up.
KampalaAges 18 years+ - NCT05300698Recruiting
Eye imaging test: MRI compared with ultrasound
This study compares two ways to look at the layers of your eye: MRI and a special, non-contact ultrasound. It may help find which test gives clearer information for diagnosing or evaluating eye conditions.
Paris, ParisAges 18 years+ - NCT05419713Recruiting
Test of how the brain processes depth and space
This study tests how people perceive depth and space using visual tasks. It may help researchers better understand normal (or well-corrected) vision and how the brain handles visual information.
Louisville, KentuckyAges 18–40 - NCT04648124Recruiting
MRI brain scan study in hereditary retinal vision loss
This study uses functional MRI (a type of brain scan) to understand how the brain processes vision in people with inherited retinal disorders. You might be included if you are an adult with hereditary retinal degeneration and are planning certain vision-related treatments soon.
Paris, PARISAges 18 years+ - NCT04985487Recruiting
Safety follow-up for brolucizumab in neovascular AMD
This study tracks the real-world safety of brolucizumab in adults with neovascular age-related macular degeneration (nAMD). If you’re already prescribed this medicine, the study may help confirm it continues to be safe and well-tolerated over time.
Daegu, Dalseo GuAges 18–100 - NCT05562947RecruitingPhase 3
Ranibizumab port implant for wet macular degeneration in Chinese adults
This Phase 3 study tests whether a small eye implant that delivers medicine on a schedule (the port delivery system) with ranibizumab works better and safely in people with wet age-related macular degeneration. It’s designed for patients who have already been treated recently with anti-VEGF injections and need continued control.
BeijingAges 50 years+ - NCT04307238Recruiting
Anesthesia types and eye response after planned ENT surgery
This study compares different types of general anesthesia by checking how your pupils (the black part of the eye) respond after surgery. It may help doctors understand which anesthesia options are better for eye-related side effects after planned ear, nose, or throat operations.
Vienna, State of ViennaAges 18–99 - NCT03653650Recruiting
Platelet-rich plasma for stubborn corneal surface wounds
This trial studies injecting your own platelet-rich plasma into the eye to help a persistent corneal surface defect heal. It may help if you have a recurring or nerve-related corneal ulcer, but it’s not for certain ulcer types or active eye infections.
Monterrey, Nuevo LeónAges Any age - NCT05916391RecruitingPhase 1
Gene therapy for diabetic macular swelling affecting vision
This early-stage (Phase 1) study tests a new gene therapy to improve vision for adults with diabetic macular edema. It mainly looks at whether the treatment can be safely given and may help your vision over time.
Tianjin, Tianjin,ChinaAges 18 years+ - NCT03662776Enrolling by invitation
How past eye-cancer treatment affects survivors’ well-being
This study looks at how different treatments for one affected eye retinoblastoma may affect survivors’ emotional and social functioning. It may help doctors understand which treatment approaches are linked with better day-to-day well-being over time.
New York, New YorkAges 8–17 - NCT05180994RecruitingPhase 1/Phase 2
Infliximab eye drops after first corneal transplant
This trial tests infliximab—given as eye drops—after a first corneal transplant to see if it can improve healing and eye outcomes. It may help people at risk of inflammation after surgery, but it also requires careful screening for infection and medication safety.
Montreal, QuebecAges 18–80 - NCT05136209Recruiting
Surgery for children’s cataracts: with or without vitrectomy
This trial compares two surgical techniques to treat cataracts present since birth in children, to see which approach works better. It may help your child by improving surgical outcomes and recovery.
Guangzhou, GuangdongAges 1 month–18 years - NCT05136950Recruiting
Tracking side effects after secondary lens surgery for cataracts
This study follows children who had congenital cataract surgery to see how often glaucoma-related side effects happen after getting a secondary intraocular lens. It may help doctors better prevent and catch eye pressure problems after these surgeries.
GuangzhouAges 1.5 years–14 years - NCT04487249Recruiting
Vision therapy trial for intermittent outward eye turning
This trial tests whether a structured vision therapy program can improve control of intermittent outward eye turning (intermittent exotropia) in children. You may be placed into one of the study groups (randomized), and the results will help doctors understand who benefits most and how well it works.
Birmingham, AlabamaAges 8–16 - NCT04628663Recruiting
Dexmedetomidine and eye pressure during spine surgeries
This study looks at whether a specific anesthesia-related medicine (dexmedetomidine) affects eye pressure during planned spine operations done with the patient lying face-down under general anesthesia. It may help doctors choose safer anesthesia to reduce risks related to eye pressure changes.
Athens, AtticaAges 18–90 - NCT04332783Recruiting
Study of vision errors during visual search tasks
This study asks people to complete visual search tasks to understand how certain types of visual mistakes happen in order. You might help researchers learn how to reduce these errors, which could guide better visual support in the future.
Berkeley, CaliforniaAges 18 years+ - NCT04275232Enrolling by invitationPhase 3
Plasma treatment for a rare eye condition from Type 1 deficiency
This trial studies donated blood-plasma samples as a treatment for ligneous conjunctivitis caused by Type 1 plasminogen deficiency. It may help reduce or improve the eye inflammation and growths linked to this specific genetic problem.
St. John's, Newfoundland and LabradorAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.