Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07870785Recruiting
Comparing viewing range of two progressive lenses in older adults
This study tests two types of progressive lenses (which help you see at different distances) to see how they affect your field of vision. It may help you find glasses that work better for daily tasks like reading and using a computer.
Seville, AndalusiaAges 52–67 - NCT05204459Recruiting
MRI and eye-scan study for MS and related conditions
This trial uses brain MRI and eye imaging tests to study research markers in people with multiple sclerosis (MS) and related neurologic conditions. It may help researchers better understand these diseases and how they change over time.
Los Angeles, CaliforniaAges 18 years+ - NCT06243497Recruiting
Comparing eye fluid and tear markers before and after UCP
This study compares levels of inflammatory markers (cytokines) in the fluid inside your eye and your tears before and after a procedure called UCP (ultrasound cycloplasty) to treat glaucoma. It aims to understand how the eye responds, which may lead to better treatments for high eye pressure.
Guangzhou, GuangdongAges Any age - NCT07854899Recruiting
Study of advanced retinal degeneration natural history
This study follows people with advanced retinal degeneration (RCD) to learn how the disease progresses over time. It does not test a new treatment, but the information may help design future treatments.
GhentAges 18 years+ - NCT04739319Recruiting
Study of age-related macular degeneration changes
This study looks closely at how age-related macular degeneration (AMD) develops and changes over time by taking detailed eye measurements. It may help researchers better understand disease progression, especially for people who already have AMD.
East Melbourne, VictoriaAges 18 years+ - NCT07858708Enrolling by invitation
Vision problems after brain injury
This study looks at vision problems that can happen after a brain injury, like a stroke, traumatic brain injury, or brain tumor. The researchers want to understand how these vision issues affect daily life, which could help improve care.
Prague, Česká RepublikaAges 18–85 - NCT01243931Recruiting
Eye scan guided laser surgery for surface cornea scars
This study tests a laser procedure guided by an eye scan to improve vision caused by surface (front) cornea cloudiness or irregularities. It may help some people whose vision problem is mainly in the outer cornea and can be safely treated without reaching deep tissue.
Portland, OregonAges 18 years+ - NCT02141308Recruiting
OCT eye imaging for rare retinal and choroid diseases
This trial studies rare diseases affecting the retina or choroid using detailed eye scans (OCT). It may help doctors better understand how these conditions look in the eye and how imaging findings relate to vision.
Portland, OregonAges 7–100 - NCT02253030Recruiting
Eye scan study for newly diagnosed wet AMD
This study uses a special eye scan (OCT angiography) to look at new, abnormal blood vessel growth in people with wet age-related macular degeneration (wet AMD) who have not been treated yet. It may help researchers better understand the disease and how it changes over time.
Portland, OregonAges 50–100 - NCT06264024Recruiting
Combined laser and crosslinking for keratoconus
This trial tests a new combined treatment for keratoconus that includes both a surface laser (phototherapeutic keratectomy) and corneal collagen crosslinking (CXL). It may help strengthen your cornea and improve vision.
OsloAges 18 years+ - NCT07873697Recruiting
Gum disease and dry eye study
This study looks at whether people who have gum disease (periodontitis) are more likely to have dry eye disease. If you have both conditions, taking part could help doctors understand how they might be connected and improve care.
Sulaymaniyah, As Sulaymaniyah GovernorateAges 30–65 - NCT06264427Recruiting
Study of metabolism issues in Greenland
This study looks at the genes and physical traits of people in Greenland with type 2 diabetes or severe obesity. It aims to better understand these conditions to improve care.
Nuuk, SermersooqAges 18 years+ - NCT07869511Recruiting
Steroid injection behind the eye for light-damage to the retina
This study tests whether a steroid injection behind the eye (a retrobulbar injection) can help people whose retina (the light-sensing layer at the back of the eye) has been damaged by looking at a strong light source, like a laser or bright flash. The treatment aims to reduce swelling and vision problems that can follow such an injury.
Hangzhou, ZhejiangAges 6 years+ - NCT06275373Recruiting
Teprotumumab for thyroid eye disease study
This study tests if the drug teprotumumab can help with symptoms of thyroid eye disease, such as bulging eyes, pain, or double vision. It is for adults who are beneficiaries of the Department of Defense (DOD).
Bethesda, MarylandAges 18 years+ - NCT06068179RecruitingPhase 2/Phase 3
Can a new combo help Graves' disease go into remission?
This trial tests a combination of two medicines (methimazole and mycophenolate) to see if they can help people with newly diagnosed Graves' disease go into remission faster and more safely. If you are newly diagnosed and haven't had treatment yet, this study might offer a way to get better control of your condition.
Xiamen, FujianAges 18–60 - NCT05714449Recruiting
Eye patch and vision training for children with amblyopia
This study compares two treatments for amblyopia (lazy eye) in children: wearing an eye patch and a special vision training called foveation therapy. It aims to see which treatment better improves vision in children with strabismic amblyopia, which is a type of lazy eye caused by misaligned eyes.
New York, New YorkAges 4–16 - NCT07868198Recruiting
Understanding family decisions about corneal donation in palliative care
This study explores what influences family members' or close friends' decisions about corneal donation for patients in palliative care. It aims to improve how donation is discussed and supported.
Paris, ParisAges 18 years+ - NCT07867080RecruitingPhase 3
Gene therapy injection for diabetic macular edema
This trial tests a one-time gene therapy injection into the eye for adults with diabetic macular edema (DME), a condition where fluid builds up in the retina and blurs vision. The goal is to reduce the need for frequent eye injections and help maintain vision over time.
Scottsdale, ArizonaAges 18 years+ - NCT05733182Recruiting
Lamp color test to prevent nearsightedness in kids
This study tests whether the color of a reading lamp can help reduce how likely children are to become or worsen nearsightedness (myopia). Your child’s eyes may be followed over time to see if the lamp type affects eye measurements.
Hong Kong, KowloonAges 4–18 - NCT06294405Recruiting
Intraocular Lens Implant Registry
This study collects information from patients who have had an intraocular lens (an artificial lens placed inside the eye during cataract surgery) to track how different lenses perform over time. It helps doctors understand which lenses work best for patients.
AugsburgAges 18 years+ - NCT06298890Recruiting
Dry eye pattern after cataract surgery
This study looks at how dry eye symptoms change after cataract surgery. It is for older adults (50–90) having simple cataract surgery for the first time, without other eye problems or certain health conditions.
KaunasAges 50–90 - NCT05710198RecruitingPhase 3
Citicoline eye drops to slow vision field loss in glaucoma
This Phase 3 trial tests whether citicoline 2% eye drops can help slow worsening of the visual field in adults with open-angle glaucoma. If you qualify, you would be monitored with repeated eye tests to see if your vision field stays more stable over time.
Milan, MIAges 18 years+ - NCT06269419Recruiting
Diabetes eye disease natural progression study
This study follows people with type 2 diabetes to understand how diabetic retinopathy (an eye disease caused by diabetes) changes over time without treatment. It may help if you have no other eye issues causing new blood vessels and are not planning for certain eye procedures.
Chengdu, SichuanAges 18–75 - NCT06237829Recruiting
Testing touch aids for people who are blind
This study tests how well touch-based aids help people who are blind or visually impaired understand math plots. The goal is to see if these tools work better for everyday use.
Newark, DelawareAges 16 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.