Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3132
- Phase 2121
- Phase 1121
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California142
- Arizona65
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT04853251RecruitingPhase 4
Study of corneal cells after a ranibizumab eye implant
This trial checks how well corneal endothelial cells (cells that help keep the cornea clear) do in people with neovascular age-related macular degeneration (nAMD) who are treated with a port-delivery implant that releases ranibizumab. It also helps doctors understand whether this method changes corneal health and stays safe while controlling the eye disease.
Mesa, ArizonaAges 50 years+ - NCT06993597Recruiting
Eye stiffness study in glaucoma patients using a special camera
This study uses a special camera (Brillouin microscopy) to measure how stiff your cornea is. It compares people with different types of glaucoma to those without glaucoma, helping researchers understand the link between corneal stiffness and eye pressure.
Baltimore, MarylandAges 18 years+ - NCT06765980RecruitingPhase 1/Phase 2
Study of KRIYA-825 for geographic atrophy in age-related macular degeneration
This trial tests an experimental drug called KRIYA-825 (also known as VV-14295) for people with geographic atrophy, a late stage of dry age-related macular degeneration that causes vision loss. The study aims to see if the treatment is safe and can help slow the progression of the disease.
Erie, PennsylvaniaAges 55–80 - NCT06806085Recruiting
Study of leftover lens material after SMILE eye surgery
This study looks at how leftover lens material after SMILE eye surgery might affect tiny vision imperfections. It aims to help people with nearsightedness get clearer, sharper results.
Nanchang, JiangxiAges 18–45 - NCT06766539Recruiting
Eye-tracking in surgical care education
This trial uses eye-tracking glasses to study how doctors and medical students learn and work before, during, and after surgery. It may help improve training and patient care.
Hangzhou, ZhejiangAges Any age - NCT06745375Enrolling by invitation
Soft contact lens fit and power study
This study looks at how soft contact lenses fit on the eye and how their power affects vision. It may help you if you wear or want to try soft contact lenses.
Birmingham, UKAges 18–60 - NCT05774704RecruitingPhase 1/Phase 2
Curcumin eye study for people with retinal amyloid deposits
This early-stage study tests whether curcumin (a natural plant compound) can affect eye changes in people who have amyloid deposits in the retina. It aims to see if the treatment is safe and possibly helpful for vision-related outcomes.
Lubbock, TexasAges 40–89 - NCT07753603RecruitingPhase 3
Linsitinib for active moderate to severe thyroid eye disease
This study tests an experimental pill (linsitinib) for people with active thyroid eye disease. Participation may help reduce eye bulging and other symptoms, especially if other treatments haven't worked.
Las Vegas, NevadaAges 18 years+ - NCT07752433Recruiting
Brain stimulation with augmented reality for lazy eye in adults
This trial tests a new treatment for adults with lazy eye (amblyopia) that combines brain stimulation with a special vision game using augmented reality. The goal is to improve vision in the weaker eye.
Porto, Porto DistrictAges 18–40 - NCT05554835Recruiting
Mitochondrial disease registry and history study
This study collects information about people who have a suspected or confirmed mitochondrial disease. It aims to better understand how the disease looks over time, which can help future treatments.
InnsbruckAges Any age - NCT06949579Recruiting
Risk of Eye Bulge in Highly Myopic Europeans
This study looks at the risk of a back-of-the-eye bulge (posterior staphyloma) in people with high myopia. It uses existing eye images to understand the anatomy of highly myopic eyes.
ParisAges 18 years+ - NCT07661056RecruitingPhase 3
A drug trial for adults with Graves' disease
This trial is testing a new drug, BHV-1300, to see if it works and is safe for people with Graves' disease. It might be an option if you have active hyperthyroidism (overactive thyroid) caused by Graves' disease and haven't had certain other treatments.
Burbank, CaliforniaAges 18–70 - NCT05770661Recruiting
Study of eye growth length in children in China
This study looks at how a child’s eye “length” changes as they grow. It may help researchers understand patterns in eye development and who may be at higher risk for future vision problems.
Shanghai, Shanghai MunicipalityAges 3–18 - NCT06043622Recruiting
Healthy eye blood vessel database study
This study uses a special eye scan (OCT angiography) to create a reference database of normal blood vessels in healthy eyes. It helps doctors compare and diagnose eye conditions later.
AmiensAges 18 years+ - NCT05966493RecruitingPhase 2
Lufepirsen gel for persistent corneal epithelial defects
This Phase 2 trial tests whether a treatment gel called NEXAGON (lufepirsen) can improve healing and safety in people with a persistent corneal problem called PCED that hasn’t gotten better despite standard non-surgical treatments. You may be a candidate if your defect has lasted at least 2 weeks and hasn’t improved recently, and if you don’t have certain eye infections or other eye conditions.
Dothan, AlabamaAges 2 years+ - NCT05668455RecruitingPhase 3
Topical treatments for irritated eyes with an eye prosthesis
This Phase 3 study compares two topical (applied to the eye) treatments to reduce inflammation-related irritation in people who wear a permanent eye prosthesis. It may help if your prosthesis-related eye discomfort is ongoing despite basic care like artificial tears.
RennesAges 18–85 - NCT05020158Recruiting
Family Talk support after a serious illness in the family
This trial tests a “Family Talk” support program for families dealing with a child’s life-threatening or life-limiting illness. It aims to help families talk and cope together during the early period after diagnosis or relapse.
StockholmAges 6 years+ - NCT07317934RecruitingPhase 3
Gene therapy for wet age-related macular degeneration
This study tests a one-time gene therapy called LX102 for wet age-related macular degeneration (AMD). It may reduce the need for frequent eye injections and help preserve vision.
Hefei, AnhuiAges 50–80 - NCT06612541Recruiting
Eye imaging test for premature babies at risk of ROP
This study tests a new eye imaging device to check for retinopathy of prematurity (ROP), a condition that can affect vision in premature babies. It may help doctors diagnose ROP earlier and more easily at the bedside.
Nashville, TennesseeAges 6 months–8 months - NCT07496567RecruitingPhase 2/Phase 3
Study of EYE201 for wet age-related macular degeneration
This trial tests a new medicine, EYE201, for people with wet age-related macular degeneration (AMD) that has not been treated before. The study will see if this drug can help improve vision and slow down vision loss.
Gilbert, ArizonaAges 50 years+ - NCT07694375RecruitingPhase 2
Eye drop study to protect corneal cells after cataract surgery
This trial tests an eye drop called CA201A to see if it can prevent loss of cells in the clear front layer of the eye (the cornea) after cataract surgery. The drop contains ascorbic acid, a form of vitamin C, and is given before and after the procedure to help protect the eyesight.
Deakin, Australian Capital TerritoryAges 18–85 - NCT07636590Recruiting
Study of vision changes in limbal stem cell deficiency
This observational study follows patients with limbal stem cell deficiency (a condition affecting cells at the edge of the cornea that help maintain healthy eye surface) to understand how their vision changes over time. Researchers will track your eye health without giving you new treatment.
Carmel, IndianaAges 12–99 - NCT06566339Recruiting
Robotic eye scan for emergency room patients
This study tests a new robotic device that uses light scans (OCT) to look at the front part of your eye. It may help find problems like redness or a foreign body without needing traditional exams.
Durham, North CarolinaAges 18 years+ - NCT04735263RecruitingTeam says not enrollingPhase 2
Testing dark vision changes as a statin response signal
This Phase 2 study looks at whether changes in night/dark adaptation can show early whether high-dose atorvastatin (a statin) is helping intermediate age-related macular degeneration (AMD). If you fit, you may help researchers find an earlier way to tell who is responding.
Boston, MassachusettsAges 50–85
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,904 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.