Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT06498947Recruiting
Understanding Natural Farsightedness in Kids
This study looks at natural changes in children's eyes that cause mild farsightedness (called "physiological hyperopia") in 6- to 9-year-olds. It aims to understand why some children have this harmless vision difference, which may help with future eye care.
Beijing, Beijing MunicipalityAges 6–9 - NCT06500728Recruiting
Vision involvement in giant cell arteritis
This study looks at how vision is affected in people with giant cell arteritis (GCA) -- a condition where blood vessels become inflamed. It compares those with GCA-related vision loss to people who have similar vision problems but not from GCA, to better understand and treat these eye issues.
Milan, LombardyAges 18 years+ - NCT07804277Recruiting
Comparing two eye pressure tests
This study compares two methods for measuring eye pressure—one using a standard device and one using a newer device—to see if they give similar results. It might help if you need a reliable, comfortable way to monitor your eye pressure.
Jacksonville, FloridaAges 22 years+ - NCT07807111RecruitingPhase 1/Phase 2
Gene therapy for advanced rod-cone dystrophy
This study tests a new gene therapy for people with advanced rod-cone dystrophy, a genetic condition that causes progressive vision loss. The treatment is given as an injection into the eye, and the study aims to see if it is safe and if it can help improve or preserve vision.
GhentAges 18 years+ - NCT07805759Recruiting
Triple action eye drops for allergy symptoms
This trial tests an eye drop called Daydrop Triple Action to see if it helps with eye itching and redness caused by allergies. It might be a good option if you have allergic conjunctivitis and have not used other allergy eye medications recently.
Madrid, MadridAges 18 years+ - NCT07804186RecruitingPhase 3
Adjuvant therapy for high-risk uveal melanoma
This trial is testing a combination of two oral medications (darovasertib and crizotinib) after standard local treatment for high-risk uveal melanoma that has not spread. The goal is to see if this treatment can reduce the risk of the cancer coming back.
Scottsdale, ArizonaAges 18 years+ - NCT07802769Recruiting
MRI brain scans for people with glaucoma
This study uses MRI scans to look at brain structure in people with glaucoma compared to healthy controls. It aims to understand how glaucoma affects the brain over time, which may help improve future treatments.
BordeauxAges 18 years+ - NCT07801625Recruiting
How eyes and nose react to grass allergy
This study looks at how people with and without grass allergies react when a small amount of grass allergen is put into the eye. It aims to understand the immune response in the eyes and nose, which may help improve allergy treatments.
Kingston, OntarioAges 18–70 - NCT07805967Recruiting
Study of rare parkinsonian conditions
This study follows people with certain rare brain conditions that affect movement and thinking, such as multiple system atrophy, dementia with Lewy bodies, progressive supranuclear palsy, and corticobasal degeneration. It aims to learn more about how these conditions progress over time, which may help improve future care.
Changshu, JiangsuAges 18 years+ - NCT06503276RecruitingPhase 2
Orelabrutinib and radiation for a type of eye lymphoma
This trial tests a combination of a targeted drug (Orelabrutinib) and radiation therapy for adults newly diagnosed with a slow-growing lymphoma around the eye. The goal is to see if this approach works well and is safe for people who have not had treatment before.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07796230Recruiting
Testing a new eye camera for people with retinal conditions
This study is testing a new camera system to take pictures of the inside of the eye (the back part where the retina is). It is for people who have eye diseases like age-related macular degeneration, glaucoma, or diabetic retinopathy. The goal is to see how well the camera works in real-world conditions.
Louisville, KentuckyAges 22 years+ - NCT06520410RecruitingPhase 4
Short vitrectomy tool for children's eye surgery
This trial tests a shorter, 18-millimeter tool for vitrectomy surgery in children. It aims to see if this smaller tool is safe and works well for treating various eye problems in kids.
TaoyuanAges birth–18 years - NCT07798323Recruiting
Imaging study for dry age-related macular degeneration
This study uses special eye scans and tests to look for blood vessel problems that may be linked to dry age-related macular degeneration (AMD). It might help find new ways to treat the condition.
Cleveland, OhioAges 50–80 - NCT07798700Recruiting
Biofluid research for brain and movement disorders
This study collects blood, spinal fluid, and other samples from people with brain or movement disorders, their family members, and healthy volunteers. The goal is to find better ways to diagnose and understand these conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07794800Recruiting
Observing eye complications after stem cell transplant
This study observes patients who have had a stem cell transplant to understand and monitor chronic graft-versus-host disease affecting the eyes. It aims to learn more about this condition to improve future care.
Shanghai, Shanghai MunicipalityAges 14 years+ - NCT07796178RecruitingPhase 4
Dry eye relief and comfort after cataract surgery
This study tests a treatment called Lacrifill to see if it helps reduce dry eye symptoms after cataract surgery. You would receive the treatment after your surgery to see if it improves comfort and eye health.
Pittsburg, KansasAges 18–80 - NCT04353960Recruiting
Study of heart rate response during eye muscle surgery
This study looks at how the heart rate changes when eye doctors move the eye muscles during strabismus (eye alignment) surgery. It may help doctors better understand and manage this normal reflex during surgery.
Anchorage, AlaskaAges 1 month–100 years - NCT07784842Recruiting
Comparing two eye muscle surgeries for large outward deviation
This study compares two surgical techniques for correcting large-angle outward eye deviation (exotropia). It aims to see which method is more effective and better maintains eye alignment when looking sideways.
Minya, Minya GovernorateAges Any age - NCT07790211RecruitingPhase 4
Eye drop for tear film stability
This study tests an eye drop to help stabilize the natural tear film on the surface of the eye. It may help people who have normal tear production but could benefit from better tear film stability.
Sioux Falls, South DakotaAges 18 years+ - NCT07790185RecruitingPhase 4
LASIK for nearsightedness: measuring vision and satisfaction
This study tests how well a new type of LASIK (called ray-tracing-guided) improves vision in low light and how satisfied patients are with the results. It is for people with mild to moderate nearsightedness who want to stop wearing glasses or contacts.
Sioux Falls, South DakotaAges 18–45 - NCT07788521Recruiting
Comparing two multifocal contact lenses for reading and distance
This trial compares two daily disposable multifocal contact lenses to see which one provides better vision for reading and distance. If you need multifocal contacts for presbyopia (age-related difficulty focusing on close objects), this study might help you find a more comfortable or clearer option.
Longwood, FloridaAges 40–70 - NCT06539481RecruitingPhase 4
ILUVIEN eye implant for kids with recurrent eye inflammation
This trial tests an eye implant (ILUVIEN) in children and teens ages 6 to 17 who have a type of eye inflammation called uveitis that keeps coming back. The implant releases medicine slowly over time to control inflammation and may help reduce the need for other treatments.
BerlinAges 6–17 - NCT05654025Recruiting
Study of eyesight outcomes after congenital lens dislocation
This follow-up study looks at how vision changes over time in children and adults with congenital lens dislocation, and what complications may occur. It may help doctors better predict outcomes and prevent problems after diagnosis.
Guangzhou, GuangdongAges 3 years+ - NCT06541626Recruiting
Study of CNS inflammatory demyelinating diseases
This study follows people with certain inflammatory conditions of the brain and spinal cord (like MS, NMOSD, or MOGAD) to learn more about their disease. If you join, you will help researchers understand these conditions better.
Guangzhou, GuangdongAges 18–65
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.