Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT04604834Recruiting
Platelet-rich plasma treatment for corneal nerve damage
This trial studies whether your own platelet-rich plasma can help heal a fragile, slow-to-recover cornea caused by reduced corneal feeling (nerve damage). It may help reduce corneal erosion and improve corneal surface healing.
Monterrey, Nuevo LeónAges 18 years+ - NCT04627428RecruitingPhase 1/Phase 2
Stem-cell–made eye tissue transplant for dry macular degeneration
This early-stage study tests whether a stem-cell–derived transplant to the back of the eye is safe and tolerable in people with dry age-related macular degeneration (AMD). If you qualify, you may receive the transplant and have close follow-up to watch for side effects.
Beverly Hills, CaliforniaAges 55 years+ - NCT04549935RecruitingPhase 4
Testing eye drops and procedures after two-eye surgery
This Phase 4 study looks at a treatment plan around the time of planned surgery on both eyes (called RLE). It may help the researchers learn how safe and effective the approach is for improving eye outcomes after surgery.
Bozeman, MontanaAges 22–75 - NCT03552562Recruiting
Eye blood-flow study in adults with type 2 diabetes
This study measures blood flow and oxygen use in the retina (the light-sensing layer at the back of your eye) in adults with type 2 diabetes and in healthy adults. It may help researchers better understand how diabetes affects the eye.
ViennaAges 18–99 - NCT04050644RecruitingPhase 4
Tested preservative-free vs standard eye drops after cataract surgery
This study compares different anti-inflammatory and pain-relief eye drops after cataract surgery to see which one works better. It focuses on whether preservative-free drops cause fewer problems (like irritation) while still protecting the eye during healing.
Leuven, Vlaams-BrabantAges 60 years+ - NCT03821467Recruiting
Eye scan study to test a new imaging method in healthy adults
This study checks whether a specific eye-scanning technology gives consistent, repeatable results. It enrolls healthy adults to see if the test works reliably before being used more broadly.
Vienna, State of ViennaAges 18–35 - NCT01617408Recruiting
Brain stimulation and vision testing in healthy adults
This study uses brain stimulation and brain imaging (MRI) along with vision tests to understand how the brain supports seeing. You might be eligible if you are a healthy adult and can safely complete MRI and stimulation tasks.
Bethesda, MarylandAges 18–50 - NCT02771236Recruiting
Study of inherited eye conditions in families
This study looks at families who have inherited (passed down) eye conditions, using eye exams and blood tests. It may help researchers understand what causes these conditions and find better ways to diagnose them.
La Jolla, CaliforniaAges 4–120 - NCT03321201Recruiting
Glue or cautery for a first pterygium surgery
This study compares two methods used during surgery for a first-time pterygium (a non-cancer growth on the eye surface): using a special glue versus cauterization. It may help determine which method works better to keep the growth from coming back and to heal more smoothly.
SplitAges 18 years+ - NCT06971939RecruitingPhase 4
Long-term safety of NT-501 implant for MacTel type 2
This study checks the long-term safety and effectiveness of the NT-501 implant for people with MacTel type 2. It is for people who have already been in an earlier NT-501 study, whether they got the real implant or a sham procedure.
La Jolla, CaliforniaAges 18 years+ - NCT02471287Recruiting
Genetics study for inherited eye conditions
This study looks at genes in people with inherited eye conditions and in close family members who may or may not have the condition. It helps researchers understand what causes these eye diseases and how they might be better studied in the future.
Bethesda, MarylandAges 1–120 - NCT04848740Enrolling by invitation
Tested implant for worsening thin corneas
This trial looks at whether placing a donor-like cornea “lenticule” implant can help people whose cornea is getting worse, becoming thin, and causing blurry or reduced vision. The goal is to see if the implant can improve corneal clarity and vision in progressive disease.
PristinaAges 20–60 - NCT05523869RecruitingPhase 2
Eye injection medicine after repeat retinal detachment surgery
This Phase 2 trial tests an injection of topotecan into the eye after surgery for retinal detachment that keeps coming back due to scar tissue (proliferative vitreoretinopathy). It may help improve how the retina heals after difficult, repeat operations when vision is usually very guarded.
Toronto, OntarioAges 18 years+ - NCT05888987Recruiting
New test for severe corneal infection diagnosis
This study tests a new method for identifying bacteria causing severe corneal infections. It may help doctors choose the right treatment faster by improving how the infection is identified from corneal samples.
ReimsAges 18 years+ - NCT07144761Recruiting
Patient feedback study on eyelid lift with Ziplyft™
This study tests a new device called Ziplyft™ for lifting excess eyelid skin. Researchers want to know how satisfied patients and surgeons are with the results.
Miami, FloridaAges 35 years+ - NCT03298737Enrolling by invitation
Study of visual attention and eye movement patterns
This study looks at how your eyes move and how you pay attention to what you see. It may help researchers understand normal eye and attention patterns and how they work.
Rochester, New YorkAges 18–65 - NCT06766357RecruitingPhase 3
Cyclosporin gel for moderate to severe dry eye
This study tests a gel form of cyclosporine for people with moderate to severe dry eye that hasn't improved with other treatments. The gel is applied to the eye to help reduce inflammation and increase tear production.
Xiamen, FujianAges 18 years+ - NCT01757132Enrolling by invitation
Mini telescope implant study for advanced age-related macular loss
This post-approval study tests whether an implantable mini telescope can improve vision in people with advanced age-related macular degeneration that affects the center of vision. You may qualify if your vision loss matches a specific pattern and you can complete required eye training before and after surgery.
Chandler, ArizonaAges 65 years+ - NCT03167203Enrolling by invitationPhase 1/Phase 2
Safety check after stem-cell eye treatment
This study follows people who previously received an embryonic stem-cell–derived treatment for macular (central) vision loss. Its goal is to watch for long-term side effects and better understand how safe the treatment is over time.
Kansas City, MissouriAges 18 years+ - NCT03063216Recruiting
Study of treatment outcomes for children with cataracts
This study looks at children who have cataracts (clouding of the eye lens) and how well treatments and eye care go. You may be able to take part if your child can cooperate with eye exams and does not have certain mental or learning conditions that affect participation.
Shanghai, Shanghai MunicipalityAges 2 months–20 years - NCT03286686Recruiting
Study of thinking and hand skills after brain injury
This study looks at how people with an injury to the back part of the brain (posterior parietal cortex) process what they see and guide their movements. It may help researchers better understand the symptoms and improve future therapies.
BronAges 18–75 - NCT06204926Recruiting
AI predicts SMILE surgery results and risks
This trial tests if an AI program can predict complications and recovery after SMILE eye surgery for nearsightedness. It may help you understand your risks if you are a candidate for this surgery.
Nanchang, JiangxiAges 18–45 - NCT06468397Recruiting
New device for sudden retinal detachment repair
This trial tests a new device for repairing a sudden retinal detachment that affects the central vision. It compares this system to standard surgery, and may be an option if you have a specific type of retinal tear in the upper part of your eye.
East Melbourne, VictoriaAges 50 years+ - NCT07656753RecruitingEarly Phase 1
Gene therapy trial for RLBP1-related retinal dystrophy
This trial tests an injection (PUMCH-E111) for people with a specific genetic form of inherited retinal dystrophy caused by RLBP1 mutations. It aims to see if the treatment is safe and can help preserve vision.
Beijing, Beijing MunicipalityAges 18–55
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.