Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05559567Enrolling by invitation
Study for new adults with early myopia and no treatment
This study checks eye measurements (like “axial length,” the distance inside the eye) in adults with new-onset nearsightedness who are not using any myopia-control treatment yet. The results may help guide how myopia-control strategies are best applied.
St Louis, MissouriAges 21–35 - NCT05557721Enrolling by invitation
Micropulse laser for open-angle or pseudoexfoliation glaucoma
This study tests a specific eye laser treatment (micropulse) for people with open-angle or pseudoexfoliation glaucoma. It may help lower eye pressure, and the study also checks whether patients can follow the treatment plan and follow-up visits.
Skövde, Västra Götaland CountyAges 18 years+ - NCT05481827Enrolling by invitationPhase 2
Safety follow-up for GT005 in geographic eye damage
This study checks the long-term safety of GT005, a treatment you received in an earlier study, for geographic atrophy related to age-related macular degeneration. It mainly asks you to come to follow-up visits and confirm how you are doing over time.
Poway, CaliforniaAges 55 years+ - NCT05432245Enrolling by invitation
Glaucoma implant placed during cataract surgery
This trial looks at whether placing a small glaucoma implant at the same time as cataract surgery can better control eye pressure in people with primary open-angle glaucoma. It may help reduce the need for medicines or improve control, depending on how your eyes respond.
Panama CityAges 40 years+ - NCT05254535Enrolling by invitation
Tele-eye screening help for rural clinics with diabetes
This study tests whether adding a structured telehealth program (video eye checks) can improve diabetic eye screening in rural health systems. Your clinic may help the researchers measure changes using shared, de-identified patient data.
Madison, WisconsinAges 18 years+ - NCT05159960Enrolling by invitation
Repeat laser eye treatment study for eligible prior participants
This study is for people who already joined an earlier selective laser eye treatment trial and were able to be followed without needing stronger additional treatments. It looks at the best plan for repeating the laser treatment when appropriate.
Skövde, Västra Götaland CountyAges 18 years+ - NCT05158049Enrolling by invitation
Study of bionic eye outcomes over time
This study follows people who already have an implanted bionic eye device to see how they do over time. It may help researchers understand what to expect day to day and guide future care.
Melbourne E., VictoriaAges Any age - NCT05132660Enrolling by invitationEarly Phase 1
Early eye treatment study for diabetic retinopathy
This early-phase study tests a treatment aimed at preventing or slowing early diabetic eye disease in people with mild, early changes. You may be considered if your diabetes is moderately controlled and your eye tests show early warning signs.
Decatur, GeorgiaAges 30–80 - NCT05074342Enrolling by invitation
Project Open study to improve eye screening for diabetes
This study uses health records to see how to increase eye exam screening for people with diabetes who may be at risk of diabetic retinopathy. It aims to help more people get timely eye checks to prevent vision problems.
Toronto, OntarioaAges 18 years+ - NCT04886492Enrolling by invitation
NMOSD patient registry to help study future treatments
This is a registry that collects health information from adults with neuromyelitis optica spectrum disorder (NMOSD). It aims to better understand NMOSD and support future research, including studies of emerging therapies.
Waltham, MassachusettsAges 18 years+ - NCT04712318Enrolling by invitation
Treatment for lingering blurry vision after trifocal lens
This study tests a treatment to improve vision in people who still have an ongoing focusing problem (residual nearsightedness or farsightedness) about 6 months after receiving a trifocal intraocular lens. It may help if your vision is still reduced despite having the lens implanted.
PristinaAges 20–45 - NCT04693663Enrolling by invitation
Relex-SMILE treatment for leftover nearsightedness after cataract surgery
This trial tests whether Relex-SMILE eye laser surgery can improve nearsightedness that remains after you’ve already had cataract surgery. It’s meant for people with a certain range of leftover nearsightedness, while excluding certain eye problems and prior eye procedures.
PristinaAges 20–70 - NCT04607369Enrolling by invitation
Test using an app to map eye vision blind spots
This trial tests how well an EyeCTester smartphone app can measure vision blind spots and distorted vision compared with standard eye tests. If you qualify, you’ll do short near-vision and “Amsler grid” style tasks in the clinic to help confirm the app is accurate.
Bellaire, TexasAges 18 years+ - NCT04598932Enrolling by invitation
Eye pressure and tissue testing for cornea health
This study uses a special, noninvasive microscope technique to study how your cornea tissue behaves. It may help doctors better understand keratoconus and corneal changes after common eye procedures.
Cleveland, OhioAges 18–60 - NCT04381611Enrolling by invitation
Study of glaucoma surgeries and laser treatments over time
This study looks at people with glaucoma or high eye pressure to understand how surgeries and laser treatments affect long-term outcomes. It may help doctors predict which treatments work best for different patients.
Lausanne, Canton of VaudAges 1–100 - NCT03999801Enrolling by invitationPhase 2
Long-term follow-up for a subretinal eye treatment
This study checks how well a previous eye treatment (RGX-314) lasts over time. There is also an extra “other eye” study for people with age-related macular degeneration affecting both eyes.
Phoenix, ArizonaAges 50 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.