Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06542276Enrolling by invitation
Single LipiFlow Treatment to Reduce Eye Drop Use
This study tests whether a single LipiFlow treatment (a warm compress machine for the eyelids) can help people with dry eye disease use fewer prescription eye drops. It may be a good option if you have been using drops like Xiidra or Restasis for a long time.
Dakota Dunes, South DakotaAges 25–65 - NCT06511700Enrolling by invitation
Nurse-led eye injections: a new care approach
This trial tests whether specially trained nurses can safely give eye injections instead of doctors. It may make treatment quicker and easier for people who need regular injections for eye conditions.
Sabadell, BarcelonaAges 18 years+ - NCT06429527Enrolling by invitation
Smartphone app for follow-up after cataract surgery
This trial tests whether checking your vision at home with a smartphone app (WHOeyes) and answering a few questions can safely replace a one-week in-person visit after cataract surgery. If you qualify, you'll help doctors see if app-based follow-up is convenient and reliable.
Guangzhou, GuangdongAges 50–80 - NCT06330324Enrolling by invitation
Reproductive choices for genetic skin conditions
This study looks at the choices families have when they carry a genetic skin condition. It aims to learn more about how prenatal testing and IVF with genetic testing can help.
Maastricht, LimburgAges Any age - NCT06275620Enrolling by invitationPhase 2
Testing a gene therapy for X-linked retinitis pigmentosa in males
This trial tests two doses of a gene therapy (AGTC-501) in males who already had one eye treated with a similar gene therapy for X-linked retinitis pigmentosa caused by RPGR mutations. The goal is to see if the treatment is safe and can help preserve or improve vision.
Jacksonville, FloridaAges 12 years+ - NCT06235567Enrolling by invitationPhase 1/Phase 2
Eye drop vs. insert for recovery after cornea crosslinking
This trial compares two ways to manage inflammation after corneal crosslinking for keratoconus: a tiny steroid insert placed in the tear duct versus standard steroid eye drops. It aims to see which option is easier and works just as well.
San Francisco, CaliforniaAges 13–64 - NCT06232616Enrolling by invitation
Eye surgery with steroid implant for membrane-related swelling
This study tests combining vitrectomy (surgery to remove the membrane from the retina) with a dexamethasone implant (a tiny steroid that is placed inside the eye to reduce swelling) for people with a specific type of eye membrane and fluid buildup in the center of the retina.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT06227962Enrolling by invitation
Thinking and quality of life in retinoblastoma survivors
This study looks at how retinoblastoma and its treatment affect thinking skills and quality of life over time. It may help doctors better support survivors and their families.
Amsterdam, North HollandAges 6 months–35 years - NCT06227299Enrolling by invitation
Long-term study of glaucoma surgeries and lasers
This study follows patients over time to see how well different glaucoma treatments (medications, laser, or surgery) work. It may help doctors learn which treatments are best for managing glaucoma and high eye pressure.
Lausanne, Canton of VaudAges 18 years+ - NCT06221592Enrolling by invitation
New glasses for slowing myopia in children
This study is testing the safety and comfort of new glasses with special lenses designed to slow down nearsightedness in children. It compares differences between the new lenses and regular lenses, and the child will wear them for a period of time to see how they feel and if there are any concerns.
Shanghai, Shanghai MunicipalityAges 6–14 - NCT06191094Enrolling by invitationPhase 4
Vabysmo before eye surgery for bleeding in diabetes
This trial tests if an injection of Vabysmo (faricimab) given before surgery can help people with eye bleeding from diabetic retinopathy. It aims to reduce blood in the eye and improve surgery outcomes.
Aurora, ColoradoAges 18 years+ - NCT06167642Enrolling by invitation
Retinal health and nerve markers in MS patients taking ofatumumab
This study looks at how ofatumumab (Kesimpta) affects the back of the eye (retina) and certain nerve proteins in the blood in people with relapsing multiple sclerosis. It may help doctors understand how well the medication is protecting the eyes and nerves.
Baltimore, MarylandAges 18–70 - NCT06117332Enrolling by invitation
AI-Enhanced Vision for People with Visual Implants
This study tests a new AI system designed to improve what people with visual prostheses 'see.' If you have an implanted device like the Argus II or Orion, you may be able to help by coming to the lab for several days of vision testing.
Santa Barbara, CaliforniaAges 18 years+ - NCT06056154Enrolling by invitation
Testing a new artificial lens for cataract surgery
This trial tests a new type of artificial lens (called Asqelio Monofocal) for people having cataract surgery. The lens is designed to give clear distance vision without glasses.
AlicanteAges 22 years+ - NCT06034379Recruiting
Special glasses vs. eye drops for nearsighted kids
This study compares two ways to slow down worsening nearsightedness in children: special electronic glasses versus low-dose atropine eye drops. It may help your child keep their eyesight from getting much worse over time.
HsinchuAges 6–13 - NCT05955638Enrolling by invitation
Dual-focus contacts to slow worsening near-sightedness
This study tests whether dual-focus soft contact lenses can help slow how quickly myopia (near-sightedness) gets worse in young university students. You may be assigned either the dual-focus lens or a control lens, and you would need to wear the lenses most days for set hours.
Bradford, West YorkshireAges 18–21 - NCT05921240Enrolling by invitation
Study on access to vision care for young people with vision needs
This study looks at what gets in the way of getting vision services for children and teens with special vision needs. It will help identify barriers and solutions by using questionnaires and interviews in Chinese.
TaipeiAges 19–99 - NCT05921162Enrolling by invitation
Long-term follow-up after a vision gene eye injection
This study checks how people who previously received a gene therapy eye injection (vMCO-I) are doing over the long term. It may help researchers understand long-lasting effects and safety.
Cuttack, OdishaAges 18 years+ - NCT05893654Enrolling by invitationPhase 1/Phase 2
Melphalan treatment to shrink eye melanoma before other therapy
This early-phase study tests whether melphalan can be used to reduce (shrink) a type of eye cancer called choroidal melanoma before additional treatment. It may help by controlling tumor size while doctors closely monitor the eye and outcomes.
Ribeirão Preto, São PauloAges 18 years+ - NCT05875090Enrolling by invitation
Glaucoma screening study for people aged 55 to 65
This trial offers eye screening for glaucoma in adults between 55 and 65 who live in specific local healthcare areas. The goal is to see how well the screening process works and improves identification of people who may have glaucoma.
LisbonAges 55–65 - NCT05859997Enrolling by invitation
CAR-T cell therapy for active autoimmune disease flare-ups
This study tests an immune-cell treatment (CAR-T, called BRL-301) in people with certain autoimmune diseases that are active and hard to control. It may help your immune system calm down if standard treatments have not worked or your disease has returned.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05839938Enrolling by invitation
Vitamin D study for kids with allergic conjunctivitis
This trial studies whether vitamin D affects the surface of the eye, the eye’s normal germs, eye inflammation, and vision in children with allergic conjunctivitis. If vitamin D helps, it could improve symptoms and eye comfort.
TaichungAges 6–18 - NCT05706220Enrolling by invitation
Eye tests to measure visual speed in multiple sclerosis
This study tests how fast and how accurately your eyes process visual information and how eye movements look in people with multiple sclerosis. It may help researchers understand vision-related effects of MS using objective eye measurements.
Valladolid, ValladolidAges 18–80 - NCT05670626Enrolling by invitation
ICL eye lens fit based on eye measurements
This study looks at how your current eyesight prescription relates to specific front-eye measurements to help choose the right implant (ICL) and its space (vault). It may help patients who have high myopia or astigmatism and can’t safely have LASIK.
Cairo, Cairo GovernorateAges 21–45
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.