Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT07396337RecruitingPhase 2
Study of QHRD106 injection for acute ischemic stroke
This trial tests an investigational drug, QHRD106, given as an injection for people who have had a moderate-to-severe acute ischemic stroke. It aims to see if the drug can help recovery when given within 24 hours after the stroke starts, and it is for patients who are not receiving standard clot-busting treatment.
Nanjing, JiangsuAges 18–80 - NCT07396376RecruitingPhase 1/Phase 2
Testing ELU42 spray for diabetic foot ulcers
This study tests a new topical spray (ELU42) to help heal diabetic foot ulcers. It may be a good option if you have a non-infected, non-ischemic ulcer and your blood sugar is reasonably controlled.
O'Fallon, IllinoisAges 18–75 - NCT07397351RecruitingPhase 2
Inhaled Aroxxen to protect the heart during stent placement
This trial tests whether an inhaled medication called Aroxxen® can protect your heart during a planned stent procedure. It may help reduce stress on the heart muscle.
Saint PetersburgAges 50–80 - NCT00556530Recruiting
Study genes and severity in 22q11.2 deletion
This study looks at how genetic differences affect how severe 22q11.2 deletion syndrome is for different people. It may help researchers understand what drives symptom severity and guide future care.
New York, New YorkAges Any age - NCT07397715Recruiting
Ultrasound signs of adenomyosis and related symptoms
This study uses ultrasound to look for signs of adenomyosis (a condition where the uterine lining grows into the muscle wall) and see how those signs relate to symptoms. It may help doctors better diagnose and treat the condition.
SosnowiecAges 18 years+ - NCT07397754Recruiting
Salty condiments study for blood pressure health
This study tests whether specially designed salty condiments can help manage blood pressure. If your blood pressure is mildly high and you’re not on medication for it, you might be a good fit.
SingaporeAges 50–75 - NCT07397845Recruiting
Stents vs drug-coated balloons for small or complex heart vessels
This trial compares two treatments—stents and paclitaxel-coated balloons—for people with narrowed heart arteries that are small, long, or complex. It aims to find which option works better to restore blood flow.
Lucerne, Canton of LucerneAges 18 years+ - NCT01429727Recruiting
Virtual registry for recent SCAD patients at Mayo Clinic
This study is a virtual registry (a way to collect and track real-world health information) for people diagnosed with SCAD at Mayo Clinic. It may help researchers better understand SCAD in groups that are often underrepresented and in urgent, recent cases.
Rochester, MinnesotaAges 18 years+ - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Chicago, IllinoisAges 18 years+ - NCT01757730Recruiting
MRI test to measure soft tissue stiffness
This trial uses a special type of MRI to estimate how stiff certain soft tissues are in the body. You may benefit by helping doctors better measure tissue stiffness, which can relate to different health problems.
Columbus, OhioAges 18 years+ - NCT00230620Recruiting
Study of inherited bleeding disorder genes in HHT families
This study looks at DNA (genetic material) in families affected by hereditary hemorrhagic telangiectasia (HHT). It aims to understand the genetic basis of HHT and why it runs in families.
LondonAges Any age - NCT01694940Recruiting
Mitochondrial disease registry and sample collection study
This trial builds a large database and collection of lab results, and possibly tissue samples, from people with suspected or diagnosed mitochondrial conditions. It helps researchers learn more about these disorders and mitochondrial DNA changes, which may improve future diagnosis and treatments.
San Diego, CaliforniaAges Any age - NCT02098252Recruiting
Study for treating brain blood vessel malformations (AVMs)
This study is looking at treatment options for people who have an abnormal cluster of blood vessels in the brain (an AVM). It may help participants by offering a structured treatment approach, depending on the AVM type and recent symptoms.
Jacksonville, FloridaAges 5 years+ - NCT00178594Recruiting
Testing bleeding and clotting issues in people
This study looks at how the body stops bleeding or forms clots in people with bleeding or clotting disorders. It may help researchers understand these conditions better and improve evaluation tests.
Houston, TexasAges 1 day–98 years - NCT01384721Recruiting
CT scan study for heart artery disease risk
This study uses a CT heart scan (with a calcium score) to better understand risk in people with suspected coronary artery disease. You may be asked to have scan-based measurements and then be followed for at least a year.
Milan, MIAges 18 years+ - NCT01241305Recruiting
One-Time DNA Study for Different Types of Vasculitis
This trial collects a one-time DNA sample to better understand vasculitis, which are illnesses where blood vessels become inflamed. It may help researchers find why these conditions happen and how they differ across people.
Los Angeles, CaliforniaAges 7 years+ - NCT00923507Recruiting
Study of blood cancers’ natural course and next treatment needs
This study follows people with certain slow-growing blood cancers (CLL/SLL, LPL/WM, and related conditions) to understand how they progress and what leads to needing treatment. It may help doctors predict changes over time and plan care more effectively.
Bethesda, MarylandAges 18–110 - NCT01805739Recruiting
Imaging tests for people before aortic valve replacement
This trial studies heart imaging tests (from multiple types of scans) for people who have a narrowed aortic valve and are being checked for a valve replacement through the catheter (often called TAVI). It may help doctors better plan the procedure and understand heart function before treatment.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT01192048Recruiting
Study genetics in congenital heart disease
This study looks at how genes may contribute to congenital heart disease. It may help researchers better understand causes and risk in families like yours.
Columbus, OhioAges Any age - NCT01143454Recruiting
Study unusual heart conditions and related genetic traits
This study looks at people with unusual or rare heart problems, or people with a family history of these issues. Doctors and researchers may collect and study your blood or tissue (and possibly store samples) to learn what causes the condition and how it may affect the heart.
Washington D.C., District of ColumbiaAges 1–100 - NCT01158482Recruiting
Track outcomes after placing or removing an IVC filter
This study follows adults who are getting an IVC filter placed or removed. It aims to better understand how patients do after the procedure, both in the short term and longer term.
Stanford, CaliforniaAges Any age - NCT01756222Recruiting
Bicuspid aortic valve registry for adults
This study is a registry that collects health information from adults with bicuspid aortic valve disease. It may help doctors better understand outcomes and guide future care for patients and families affected by this condition.
Ann Arbor, MichiganAges 18 years+ - NCT01621594Recruiting
Testing new radiation methods for heart CT images
This trial studies newer ways to take heart and blood vessel CT scans while using radiation more carefully. It may help improve image quality for people needing coronary CT angiography.
Bethesda, MarylandAges 18–100 - NCT01534299Recruiting
Registry study for kidney nerve treatment candidates
This is a study that collects information from people who may receive a kidney-nerve procedure to help treat high blood pressure. If you qualify as a candidate and consent, the study helps doctors understand how the treatment is used in real-world care.
Homburg, SaarlandesAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.