Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT07181733Recruiting
BNP in Teens with Metabolic Syndrome
This study is looking at how heart function tests taken in the first month of life relate to metabolic syndrome (a group of conditions like high blood pressure and blood sugar) in teens. Researchers will use data already collected from when you were a baby.
Pavia, paviaAges 13–18 - NCT07179471Recruiting
Fake Carbs Practice with MiniMed 780G for Kids with T1D
This trial tests whether using a practice 'fake carbs' method helps children and teens with type 1 diabetes manage their glucose levels better with the MiniMed 780G insulin pump in auto mode.
Athens, AtticaAges 7–19 - NCT07182175Enrolling by invitation
Heart health during adrenal tumor surgery study
This study looks at how different types of adrenal tumors might affect the heart during and after surgery. It aims to help doctors understand and reduce the risk of heart injury in patients having these tumors removed.
BeijingAges 18 years+ - NCT07183579Recruiting
Finding the right dose of burosumab for XLH
This study looks at how young people with X-linked hypophosphataemia (XLH) respond to different doses of burosumab. The goal is to find the best dose to manage the condition.
NottinghamAges 2–18 - NCT07182526RecruitingPhase 2
Quercetin or alpha lipoic acid for PCOS symptoms
This trial tests adding quercetin or alpha lipoic acid to standard PCOS care to see if they improve symptoms and blood markers. It may help women who have irregular periods or signs of excess androgens like acne.
Baghdad, KarkhAges 18 years+ - NCT07180316Recruiting
Comparing robotic vs. laparoscopic surgery for weight loss revision
This trial compares two types of surgery (robotic and laparoscopic) to see which leads to fewer problems after a second weight-loss operation. It is for people who need to revise their first bariatric surgery to a Roux-en-Y gastric bypass.
LyonAges 18–70 - NCT07176234Enrolling by invitation
Linking exercise for better stress management in teens
This study tests whether a home-based exercise program can help African American teens (ages 11–16) manage daily stress. It compares the program to a healthy lifestyle education group.
Columbia, South CarolinaAges 11–16 - NCT07179926Recruiting
Impact of pasireotide on bone health in acromegaly
This trial studies how pasireotide LAR—a drug that controls growth hormone levels—affects bone health in people with acromegaly whose disease is not well-controlled after 6 months of another therapy. It may help patients understand the bone benefits of switching to this treatment.
Rome, RMAges 18 years+ - NCT07179107Recruiting
Staying hydrated for better health
This study looks at whether drinking enough water can improve your health. You'll need to be available at the same time for 8 weeks in a row.
Phoenix, ArizonaAges 20–65 - NCT07178353Recruiting
How bedrest affects leg muscles in young adults
This study looks at how 5 days of complete bedrest changes the leg muscles of healthy young adults. It may help researchers understand muscle loss and how to prevent it.
Kingston, OntarioAges 18–30 - NCT07181018Recruiting
Metabolic syndrome study in Polish twins
This study looks at how metabolic syndrome (a cluster of conditions like high blood pressure, high blood sugar, and extra belly fat) runs in twins. It aims to better understand genetic and lifestyle factors, and may help you learn more about your own health risks.
Poznan, WielkopolskaAges 15–44 - NCT07183761RecruitingPhase 2
Stem cell therapy for diabetic nerve pain
This study tests whether umbilical cord stem cells can help people with diabetic nerve damage in their legs who haven't gotten enough relief from standard treatments. It aims to improve symptoms like numbness, pain, and tingling.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT07175701Recruiting
Reducing ultra-processed foods and tracking blood sugar
This study tests whether reducing ultra-processed foods (like packaged snacks and sugary drinks) can help young adults maintain healthier blood sugar levels. You will wear a small sensor to track your glucose continuously for up to 2 weeks and receive guidance on cutting back on these foods.
Seoul, SeoulAges 20–39 - NCT07176923RecruitingEarly Phase 1
Gene editing for familial chylomicronemia syndrome (FCS)
This study tests a new gene-editing treatment called CS-121 for people with FCS whose triglycerides remain very high despite standard therapy. It aims to lower triglyceride levels by editing the APOC3 gene.
Hefei, AnhuiAges 18–55 - NCT07179692RecruitingPhase 1
CEA-targeted CAR-T therapy for advanced solid tumors
This trial tests a type of immunotherapy called CAR-T, which is designed to recognize and attack cancer cells that have a protein called CEA on their surface. It's for people with advanced cancers like colorectal, esophageal, gastric, pancreatic, lung, or bile duct cancer who have tried at least two standard treatments.
Hefei, AnhuiAges 18 years+ - NCT07180355RecruitingPhase 1
Gene therapy trial for Friedreich's ataxia
This trial tests a gene therapy called SGT-212 for people with Friedreich's ataxia. It aims to help treat the condition by delivering a working copy of the gene.
Los Angeles, CaliforniaAges 18–40 - NCT07179640RecruitingPhase 1/Phase 2
Testing ALE1 for hypophosphatasia in healthy people and patients
This trial tests a new medicine called ALE1 for hypophosphatasia (HPP), a rare bone condition. It first checks safety in healthy volunteers, then tests if the medicine helps people with HPP.
WürzburgAges 18–50 - NCT07182149RecruitingPhase 1
Testing a new drug for advanced solid tumors
This trial tests a new drug called NRM-823 for people with several types of advanced cancer that have stopped responding to standard treatments. The goal is to see if the drug is safe and how well it works.
Denver, ColoradoAges 18 years+ - NCT07183228Recruiting
Eatit weight-loss program for obesity
This trial tests a dietitian-led program called Eatit to help people with obesity lose weight and improve their eating habits. It's designed for adults who meet certain weight and health criteria.
Stockholm, Stockholm CountyAges 18 years+ - NCT06949891Recruiting
Keto diet for acromegaly
This trial tests if a ketogenic (very low-carb) diet can help lower IGF-I levels in people with acromegaly who are already on stable medication. If you have acromegaly and your IGF-I levels are still above normal despite treatment, this diet might offer an additional way to manage your condition.
RotterdamAges 18 years+ - NCT05827796RecruitingPhase 1/Phase 2
Testing IN10018 plus chemo with an added antibody in pancreatic cancer
This Phase 1/2 trial tests a new medicine (IN10018) and a specific added antibody (KN046) together with standard chemotherapy for advanced pancreatic cancer. It aims to see whether this combination can better control the cancer and how safely it can be given.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06212479Recruiting
Whole-body MRI for Preventive Health Screening
This study uses whole-body MRI to see if it can find health issues early in people without symptoms. The goal is to learn if this scan can help predict clinically important conditions in routine preventive care.
Watertown, MassachusettsAges 18 years+ - NCT06458010RecruitingEarly Phase 1
Gene therapy trial for inherited high cholesterol
This trial tests a new gene therapy called YOLT-101 for people with familial hypercholesterolemia, a genetic condition that causes very high cholesterol. The treatment aims to lower cholesterol levels and reduce heart risks.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06610162Recruiting
Metabolic responses to fasting and overfeeding in women
This study looks at how women's bodies burn energy (thermogenesis) when they fast or eat a lot. Researchers want to understand how these processes differ in premenopausal vs. postmenopausal women.
Aurora, ColoradoAges 18–65
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.