Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT07190378Enrolling by invitation
Predicting and tracking steroid-related diabetes
This study looks at how to predict and monitor diabetes caused by steroid medications. It may help if you are about to start taking steroids for a medical condition and do not have diabetes.
Warsaw, WarsawAges 18 years+ - NCT07193069Recruiting
Metformin overdose in the ICU – signs and dapagliflozin effects
This study looks at patients who are in the ICU after taking too much metformin (a diabetes drug), sometimes along with another drug called dapagliflozin (Farxiga). The goal is to understand how overdose affects the body and what signs doctors should watch for.
Saint-Denis, FranceAges 18 years+ - NCT07189234RecruitingPhase 2
Time-restricted eating for better heart health
This trial tests if eating all your meals within a shorter window each day can improve blood sugar, blood pressure, and cholesterol. You may qualify if you have prediabetes or metabolic syndrome and eat over 12 hours daily.
La Jolla, CaliforniaAges 18–75 - NCT07189091RecruitingPhase 4
Reducing IV fluids in ICU patients
This trial tests if lowering the amount of salt water (sodium chloride) given as maintenance fluids or 'fluid creep' can help critically ill adults in the ICU recover better. It compares two ways of managing daily fluids to see which is safer and more effective.
AntwerpAges 18 years+ - NCT07189195RecruitingPhase 1
TR-002 for advanced solid tumors and pancreatic cancer
This trial tests a new drug called TR-002 in people with advanced solid tumors (cancer that has spread) who have run out of standard treatment options. It includes a specific group for people with pancreatic cancer that is no longer responding to chemotherapy.
Sacramento, CaliforniaAges 18 years+ - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07186660RecruitingPhase 2
Studying a new insulin sensitizer for type 1 diabetes
This trial tests an oral medication that may help your body respond better to insulin. It's for people with type 1 diabetes who use an automated insulin pump and are willing to take a daily pill for 12 weeks.
Charlottesville, VirginiaAges 18–45 - NCT07190170Recruiting
Time-Restricted Eating for Weight Loss Maintenance
This study tests whether a time-restricted eating schedule (when you eat all your meals within a certain window each day) helps people keep off weight they've recently lost. Using a smartphone app, you'll log your meals and follow a daily eating window to see if it helps you maintain your weight loss.
New York, New YorkAges 25–65 - NCT07185555Recruiting
Low-carb diet for type 1 diabetes and obesity
This study tests a very low-energy ketogenic diet (a special low-carb, low-calorie diet) in adults with type 1 diabetes and obesity who use an automated insulin pump. It aims to see if this diet helps with weight loss and blood sugar control.
Bari, ItalyAges 18–99 - NCT07192861Enrolling by invitation
Beta pilot study for type 1 diabetes with wearable devices
This study tests how well wearable devices like a smart ring and wristband can track your glucose levels. It may help you better manage your type 1 diabetes without fingersticks.
San Francisco, CaliforniaAges 18 years+ - NCT07187388Recruiting
Electrical stimulation for jaw pain in motor neuron disease
This study tests whether gentle electrical stimulation around the jaw can ease facial pain, improve jaw movement, and help oral health in people with certain motor neuron diseases like ALS or PLS. It may be a good fit if you have jaw pain and meet a few health conditions.
Davie, FloridaAges 18 years+ - NCT04404400RecruitingPhase 3
Hydrocortisone and fludrocortisone for critical illness hormone shortage
This Phase 3 trial tests whether giving hydrocortisone plus fludrocortisone to critically ill ICU patients with suspected “corticosteroid insufficiency” can improve outcomes without relying on steroids already being used. It may help patients whose bodies aren’t making enough stress hormones during severe illness.
GarchesAges 18 years+ - NCT06767774RecruitingPhase 4
Comparing two cholesterol treatments for heart patients
This study compares two different ways of lowering cholesterol: a moderate statin (pitavastatin) plus another drug (ezetimibe) versus a stronger statin alone. The goal is to see which approach is safer regarding the risk of developing new diabetes.
SeoulAges 18 years+ - NCT06938464Recruiting
Probiotics to prevent gestational diabetes in high-risk women
This study tests whether taking probiotics (friendly bacteria) during early pregnancy can help prevent gestational diabetes in women who are at higher risk for it.
Hangzhou, ZhejiangAges 18–50 - NCT06947213Recruiting
Orthorexia nervosa in women with postmenopausal osteoporosis
This study looks at whether women with osteoporosis after menopause have a higher risk of orthorexia nervosa, an unhealthy obsession with healthy eating. It aims to compare women with and without osteoporosis to understand the connection.
IstanbulAges 55–75 - NCT05309395RecruitingPhase 3
Food prescriptions to help Latino families eat affordably
This trial tests whether giving free/covered “food prescriptions” helps multigenerational Latino households lose weight by improving diet within a budget. It may help families who want to eat healthier without worrying as much about grocery costs.
Pasadena, CaliforniaAges 2 years+ - NCT07181213Enrolling by invitation
Genetic links to high blood pressure
This trial is for people who took part in a large study (SCAPIS) and have both a certain genetic trait and high blood pressure. The goal is to understand how your genes may affect blood pressure.
Linköping, Östergötland CountyAges 50 years+ - NCT06575868Recruiting
Can myo-inositol prevent gestational diabetes in pregnancy?
This study tests whether a supplement called myo-inositol (a natural sugar-like substance) can help prevent gestational diabetes in pregnant women with obesity. If you join, you will wear a continuous glucose monitor to track your blood sugar levels and might take the supplement or a placebo.
Boston, MassachusettsAges 18–45 - NCT06587802RecruitingPhase 2
PD-1 antibody and radiation for advanced adrenal cancer
This trial tests a combination of an immunotherapy drug (PD-1 antibody) and radiation therapy for people with adrenal cortical carcinoma that has come back or spread and can't be removed with surgery. The goal is to see if this combination can help shrink or control the cancer when other treatments have stopped working.
Guangzhou, GuangdongAges 18 years+ - NCT07179926Recruiting
Impact of pasireotide on bone health in acromegaly
This trial studies how pasireotide LAR—a drug that controls growth hormone levels—affects bone health in people with acromegaly whose disease is not well-controlled after 6 months of another therapy. It may help patients understand the bone benefits of switching to this treatment.
Rome, RMAges 18 years+ - NCT07175701Recruiting
Reducing ultra-processed foods and tracking blood sugar
This study tests whether reducing ultra-processed foods (like packaged snacks and sugary drinks) can help young adults maintain healthier blood sugar levels. You will wear a small sensor to track your glucose continuously for up to 2 weeks and receive guidance on cutting back on these foods.
Seoul, SeoulAges 20–39 - NCT07179107Recruiting
Staying hydrated for better health
This study looks at whether drinking enough water can improve your health. You'll need to be available at the same time for 8 weeks in a row.
Phoenix, ArizonaAges 20–65 - NCT07181018Recruiting
Metabolic syndrome study in Polish twins
This study looks at how metabolic syndrome (a cluster of conditions like high blood pressure, high blood sugar, and extra belly fat) runs in twins. It aims to better understand genetic and lifestyle factors, and may help you learn more about your own health risks.
Poznan, WielkopolskaAges 15–44 - NCT07178353Recruiting
How bedrest affects leg muscles in young adults
This study looks at how 5 days of complete bedrest changes the leg muscles of healthy young adults. It may help researchers understand muscle loss and how to prevent it.
Kingston, OntarioAges 18–30
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.