Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06953505Recruiting
At-home ammonia monitoring for inherited metabolic disorders
This trial tests a device for measuring ammonia levels at home in people with rare metabolic conditions that cause high ammonia. It aims to make monitoring easier and more convenient for patients.
Portland, OregonAges 12 years+ - NCT06958523Recruiting
Apple Health Study for US iPhone users
This study uses your iPhone and optional devices like Apple Watch to collect health data over time. It aims to discover how technology can help monitor and improve health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06962098RecruitingPhase 2
Study of isuzinaxib for diabetic kidney disease
This trial tests an investigational drug called isuzinaxib (APX-115) for people with type 2 diabetes and diabetic kidney disease (DKD). The goal is to see if it can help protect kidney function. Participants must have stable kidney lab values and be on certain blood pressure or diabetes medications.
Ansan-siAges 19 years+ - NCT06955416RecruitingPhase 2/Phase 3
REAMBERIN for rehydration in diabetic ketoacidosis
This trial tests a solution called REAMBERIN to help rehydrate people with diabetic ketoacidosis (DKA). If you are 18–75 and have DKA with very high blood sugar and acidic blood, you may be able to join.
ArkhangelskAges 18–75 - NCT06953999RecruitingPhase 3
Testing immunotherapy plus chemo for metastatic pancreatic cancer
This trial tests a new immunotherapy drug called ivonescimab combined with chemotherapy, with or without another experimental drug (AK117), for people with pancreatic cancer that has spread. The goal is to see if adding these therapies can help shrink tumors or slow the cancer's growth.
Harbin, HeilongjiangAges 18–75 - NCT06959615RecruitingPhase 1/Phase 2
Study of JAB-23E73 for KRAS-Altered Advanced Tumors
This trial tests an experimental pill (JAB-23E73) for people with advanced solid tumors that have a specific KRAS gene change. It aims to see if the drug can shrink or slow the growth of these cancers.
Hefei, AnhuiAges Any age - NCT06953089RecruitingPhase 2
Combination therapy study for advanced solid tumors
This trial is testing two new drugs (DB-1311 with BNT327 or DB-1305) in people with certain advanced or metastatic solid tumors that have not responded to prior treatments. It aims to see if the combination shrinks tumors or slows cancer growth.
Los Angeles, CaliforniaAges 18 years+ - NCT06824623Recruiting
Preventing dehydration after ileostomy surgery
This trial tests a program to help patients with a new ileostomy avoid dehydration and hospital readmission by providing extra support and education.
Legnano, ItalyAges 18 years+ - NCT06959901Recruiting
Health tracking app study for Hispanic teens
This trial tests a mobile app that helps teens keep track of their health habits, like physical activity and eating. It is designed for Hispanic or Latino teens ages 12-18 who have a BMI in a certain range and own an iPhone.
Houston, TexasAges 12–18 - NCT06958328RecruitingPhase 3
Higher dose radiation for locally advanced pancreatic cancer
This trial tests whether giving a higher dose of radiation to the pancreas is safe and effective for people with locally advanced pancreatic cancer who have already had chemotherapy without progression.
Gilbert, ArizonaAges 18 years+ - NCT06961591Recruiting
Cooking skills for long-term weight loss in young adults with ID
This program teaches cooking skills to help young adults with intellectual disabilities lose weight and keep it off for 2 years. You’ll learn to prepare healthier meals with support from a family member or caregiver.
Kansas City, KansasAges 18–35 - NCT06961071RecruitingPhase 1/Phase 2
Parathyroid transplant for low parathyroid hormone
This trial tests whether a donated parathyroid gland can help people with low parathyroid hormone (hypoparathyroidism) control their calcium levels and reduce symptoms. Participants will receive transplant and short-term immune-suppressing drugs.
San Francisco, CaliforniaAges 18 years+ - NCT06960005Enrolling by invitation
Exercise to improve muscle and reduce falls in thyroid disease
This study tests whether a special exercise program can help older women with thyroid disease improve muscle strength, quality of life, and reduce falls. You would do supervised rhythm-based multitask exercises (like stepping and moving to music) several times a week.
GistrupAges 65 years+ - NCT06954844Enrolling by invitation
Study of ear stimulation for weight-related health in young adults
This study tests whether a gentle electrical stimulation of the ear (tVNS) can affect how the body handles weight. It aims to understand the brain and body changes related to obesity. Participants will receive the stimulation and undergo brain scans.
BonnAges 18–40 - NCT06953180Recruiting
Epigenetics, aging, and disease prevention study in Kazakhstan
This study looks at how your genes and environment affect your risk for non-communicable diseases like heart disease or diabetes. It aims to predict your biological age and help create personalized prevention plans.
Almaty, KazakhstanAges 18–69 - NCT06958640Enrolling by invitation
Da Qing offspring health study
This study looks at the health of children, grandchildren, and great-grandchildren of people who took part in a diabetes prevention study in Daqing, China. It aims to understand how their family history affects their health over time.
Beijing, Beijing MunicipalityAges Any age - NCT06957691RecruitingPhase 2
Fezolinetant for hot flashes in men on hormone therapy
This study tests a medication called fezolinetant to see if it reduces hot flashes in men undergoing hormone therapy for prostate cancer. If you experience frequent hot flashes, this treatment might help alleviate them.
Boston, MassachusettsAges 40 years+ - NCT06953232Recruiting
Protein drink for heart and brain in midlife women
This study tests a special protein drink (whey with milk fat globule membrane) to see if it helps your heart and brain after a high-fat breakfast. It might help you if you are a postmenopausal woman at moderate risk for heart disease.
Loughborough, LeicestershireAges 50–75 - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT06953193Recruiting
Comparing anesthesia types for pancreas surgery
This study compares two types of anesthesia for people having pancreatoduodenectomy surgery. It tests whether adding an epidural to general anesthesia can help prevent low blood pressure during the operation.
Mexico City, Mexico CityAges 18 years+ - NCT06957548Enrolling by invitation
Heart and diabetes risk in Cameroon adults
This study looks at risk factors for heart disease and diabetes in adults living in or from Cameroon. It involves a simple screening to better understand your health.
Douala, Littoral RegionAges 18 years+ - NCT06954909Enrolling by invitation
Hydration self-assessment for firefighters
This study looks at how well firefighters can check their own hydration using urine color. You may help by providing urine and blood samples over a few days.
Phoenix, ArizonaAges 18–65 - NCT06954584RecruitingPhase 3
Fluzoparib with or without bevacizumab or diet for advanced ovarian cancer
This trial tests if adding bevacizumab (a drug that blocks blood vessel growth) or a special diet to fluzoparib (a PARP inhibitor) works better than fluzoparib alone for women with advanced ovarian cancer whose tumors have specific genetic features (HRD-positive or HRD-negative). It is for patients who have already responded well to initial chemotherapy.
Wuhan, HubeiAges 18 years+ - NCT06961084RecruitingPhase 2
I-124 PET/CT scan for diagnosing thyroid cancer
This trial tests whether a new type of scan (I-124 PET/CT) can better detect thyroid cancer compared to standard scans. It may help doctors decide on the best treatment, such as radiation therapy or surgery.
San Francisco, CaliforniaAges 13 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.